SI2260101T1 - MicroRNA (miRNA) miR-21 test za diagnostiko - Google Patents

MicroRNA (miRNA) miR-21 test za diagnostiko

Info

Publication number
SI2260101T1
SI2260101T1 SI200930690T SI200930690T SI2260101T1 SI 2260101 T1 SI2260101 T1 SI 2260101T1 SI 200930690 T SI200930690 T SI 200930690T SI 200930690 T SI200930690 T SI 200930690T SI 2260101 T1 SI2260101 T1 SI 2260101T1
Authority
SI
Slovenia
Prior art keywords
microrna
mir
mirna
diagnostic
therapeutic purposes
Prior art date
Application number
SI200930690T
Other languages
English (en)
Inventor
Thomas Thum
Johann Bauersachs
Stefan Engelhardt
Carina Gross
Original Assignee
Julius-Maximilians-Universitaet Wuerzburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Julius-Maximilians-Universitaet Wuerzburg filed Critical Julius-Maximilians-Universitaet Wuerzburg
Publication of SI2260101T1 publication Critical patent/SI2260101T1/sl

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    • AHUMAN NECESSITIES
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    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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SI200930690T 2008-02-27 2009-02-26 MicroRNA (miRNA) miR-21 test za diagnostiko SI2260101T1 (sl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US3183508P 2008-02-27 2008-02-27
EP20080003570 EP2096171A1 (en) 2008-02-27 2008-02-27 MicroRNA (miRNA) and down-stream targets for diagnostic and therapeutic purposes
US3334008P 2008-03-03 2008-03-03
PCT/EP2009/051986 WO2009106477A1 (en) 2008-02-27 2009-02-19 Microrna (mirna) and down-stream targets for diagnostic and therapeutic purposes
PCT/EP2009/001590 WO2009106367A1 (en) 2008-02-27 2009-02-26 Microrna (mirna) and downstream targets for diagnostic and therapeutic purposes
EP09714079.2A EP2260101B1 (en) 2008-02-27 2009-02-26 Microrna (mirna) mir-21 for diagnostic and therapeutic purposes

Publications (1)

Publication Number Publication Date
SI2260101T1 true SI2260101T1 (sl) 2013-10-30

Family

ID=39639202

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200930690T SI2260101T1 (sl) 2008-02-27 2009-02-26 MicroRNA (miRNA) miR-21 test za diagnostiko

Country Status (24)

Country Link
US (10) US8236777B2 (sl)
EP (3) EP2096171A1 (sl)
JP (2) JP6033527B2 (sl)
KR (1) KR101697482B1 (sl)
CN (1) CN102027113B (sl)
AU (1) AU2009218704C1 (sl)
BR (1) BRPI0907565B1 (sl)
CA (2) CA2716643C (sl)
CY (1) CY1114426T1 (sl)
DK (1) DK2260101T3 (sl)
EA (1) EA020335B1 (sl)
ES (1) ES2436885T3 (sl)
HK (1) HK1150857A1 (sl)
HR (1) HRP20130766T1 (sl)
IL (1) IL207704A (sl)
ME (1) ME01600B (sl)
MX (2) MX336299B (sl)
MY (1) MY159454A (sl)
NZ (1) NZ588185A (sl)
PL (1) PL2260101T3 (sl)
PT (1) PT2260101E (sl)
SI (1) SI2260101T1 (sl)
UA (1) UA100727C2 (sl)
WO (2) WO2009106477A1 (sl)

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EP2096171A1 (en) 2008-02-27 2009-09-02 Julius-Maximilians-Universität Würzburg MicroRNA (miRNA) and down-stream targets for diagnostic and therapeutic purposes
WO2011017697A1 (en) * 2009-08-07 2011-02-10 New York University Compositions and methods for treating inflammatory disorders
CN102038959B (zh) * 2009-10-26 2012-12-19 中国科学院上海生命科学研究院 let-7/miR-98家族在制备治疗FAS基因相关疾病的药物中的应用
WO2011126842A2 (en) * 2010-03-30 2011-10-13 Regulus Therapeutics Inc. Targeting micrornas for the treatment of cardiac disorders
WO2011154553A2 (en) 2010-06-11 2011-12-15 Cellartis Ab Novel micrornas for the detection and isolaton of human embryonic stem cell-derived cardiac cell types
US8815826B2 (en) 2010-07-23 2014-08-26 Regulus Therapeutics, Inc. Targeting microRNAs for the treatment of fibrosis
KR20140004646A (ko) * 2010-12-15 2014-01-13 미라젠 세러퓨틱스 잠금 뉴클레오티드를 포함하는 마이크로rna 억제제
SI3211082T1 (sl) * 2011-04-25 2021-08-31 Sanofi Spojine mikroRNA in postopki za spreminjanje delovanja MIR-21
ES2651515T3 (es) * 2011-09-06 2018-01-26 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. La familia miARN-212/132 como diana terapéutica
KR20140091688A (ko) 2011-10-06 2014-07-22 미라젠 세러퓨틱스 인코포레이티드 마이크로rna 조절에 의한 전신 에너지 항상성의 제어
EP2592145A1 (en) * 2011-11-11 2013-05-15 Medizinische Hochschule Hannover Medicament for the treatment of cardiac disease
MX2014006130A (es) * 2011-11-22 2015-04-13 Intermune Inc Metodos de diagnostico y tratamiento de la fibrosis pulmonar idiopatica.
JP2015501843A (ja) * 2011-12-13 2015-01-19 オハイオ・ステイト・イノベーション・ファウンデーション miR−21およびmiR−29a、エキソソーム阻害、およびがん転移に関する方法および組成物
EP2836219A1 (en) * 2012-04-10 2015-02-18 INSERM - Institut National de la Santé et de la Recherche Médicale Methods for the treatment of nonalcoholic steatohepatitis
BR112014026639A8 (pt) * 2012-04-25 2018-01-16 Regulus Therapeutics Inc compostos , métodos de inibição da atividade de mir-21 , método para diminuir a expressão de colágeno , método para tratar , prevenir ou atrasar o início de uma doença , método de tratamento de um distúrbio fibroproliferativo e usos de um composto.
ES2801875T3 (es) 2012-06-21 2021-01-14 Miragen Therapeutics Inc Inhibidores basados en oligonucleótidos que comprenden un motivo de ácido nucleico bloqueado
CA2782942C (en) * 2012-07-12 2019-08-27 Canadian Blood Services Method for inducing immune tolerance using polymer-modified antigenic leukocytes
UA116639C2 (uk) 2012-10-09 2018-04-25 Рег'Юлес Терап'Ютікс Інк. Способи лікування синдрому альпорта
US11007221B2 (en) 2013-07-12 2021-05-18 Canadian Blood Services Acellular pro-inflammatory compositions, process for making same and methods of using same
EP3060664B1 (en) 2013-10-25 2021-07-07 Sanofi Microrna compounds and methods for modulating mir-21 activity
WO2015086828A1 (en) * 2013-12-12 2015-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and treatment of diabetic cardiomyopathy using mir-424/322
CA2954440A1 (en) 2014-07-10 2016-01-14 Canadian Blood Services Combination therapy of acellular pro-tolerogenic and pro-inflammatory preparations for modulating the immune system
CA2960387A1 (en) * 2014-09-08 2016-03-17 MiRagen Therapeutics, Inc. Mir-29 mimics and uses thereof
EA201791644A1 (ru) 2015-01-20 2018-01-31 Мираджен Терапьютикс, Инк. Ингибиторы mir-92 и их применение
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