SI2038260T1 - Stereoselektivna sinteza (S)-1-metil-3-fenilpiperazina - Google Patents

Stereoselektivna sinteza (S)-1-metil-3-fenilpiperazina

Info

Publication number
SI2038260T1
SI2038260T1 SI200730428T SI200730428T SI2038260T1 SI 2038260 T1 SI2038260 T1 SI 2038260T1 SI 200730428 T SI200730428 T SI 200730428T SI 200730428 T SI200730428 T SI 200730428T SI 2038260 T1 SI2038260 T1 SI 2038260T1
Authority
SI
Slovenia
Prior art keywords
phenylpiperazine
methyl
stereoselective synthesis
stereoselective
synthesis
Prior art date
Application number
SI200730428T
Other languages
English (en)
Inventor
Vliet Michiel Christian Alexander Van
Gerardus Johannes Kemperman
Goedheijt Marcel Schreuder
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of SI2038260T1 publication Critical patent/SI2038260T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
SI200730428T 2006-06-16 2007-06-14 Stereoselektivna sinteza (S)-1-metil-3-fenilpiperazina SI2038260T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06115607 2006-06-16
PCT/EP2007/055914 WO2007144409A1 (en) 2006-06-16 2007-06-14 Stereoselective synthesis of (s)-1-methyl-3-phenylpiperazine
EP07730171A EP2038260B1 (en) 2006-06-16 2007-06-14 Stereoselective synthesis of (s)-1-methyl-3-phenylpiperazine

Publications (1)

Publication Number Publication Date
SI2038260T1 true SI2038260T1 (sl) 2011-01-31

Family

ID=36781960

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200730428T SI2038260T1 (sl) 2006-06-16 2007-06-14 Stereoselektivna sinteza (S)-1-metil-3-fenilpiperazina

Country Status (13)

Country Link
US (1) US20100036126A1 (sl)
EP (1) EP2038260B1 (sl)
JP (1) JP5216762B2 (sl)
CN (1) CN101472901B (sl)
AR (1) AR061378A1 (sl)
AT (1) ATE479663T1 (sl)
DE (1) DE602007008898D1 (sl)
ES (1) ES2349484T3 (sl)
MX (1) MX2008016121A (sl)
PL (1) PL2038260T3 (sl)
SI (1) SI2038260T1 (sl)
TW (1) TW200815370A (sl)
WO (1) WO2007144409A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102153620A (zh) * 2005-09-26 2011-08-17 住友化学株式会社 光学活性的哌嗪化合物的制造方法
AR066005A1 (es) 2007-04-11 2009-07-15 Organon Nv Un metodo para la preparacion de un enantiomero de una benzazepina tetraciclica

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189199C (nl) * 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
DE60125915T2 (de) * 2000-02-21 2007-10-11 Nissan Chemical Industries, Ltd. Verfahren zum herstellen von chinolinderivaten und deren intermediaten
HUP0401921A3 (en) * 2001-09-14 2008-03-28 Medichem Sa Intermediate compounds for the preparation of mirtazapine and the production methods thereof
US7041826B2 (en) * 2003-06-02 2006-05-09 Aurobindo Pharma Ltd. Process for preparing 1-methyl-3-phenylpiperazine using a novel intermediate
UA83666C2 (ru) * 2003-07-10 2008-08-11 Н.В. Органон Способ получения энантиомерно чистого миртазапина

Also Published As

Publication number Publication date
MX2008016121A (es) 2009-01-15
DE602007008898D1 (de) 2010-10-14
JP2009539939A (ja) 2009-11-19
US20100036126A1 (en) 2010-02-11
ATE479663T1 (de) 2010-09-15
TW200815370A (en) 2008-04-01
PL2038260T3 (pl) 2011-02-28
CN101472901A (zh) 2009-07-01
ES2349484T3 (es) 2011-01-04
AR061378A1 (es) 2008-08-20
CN101472901B (zh) 2011-08-03
WO2007144409A1 (en) 2007-12-21
EP2038260B1 (en) 2010-09-01
JP5216762B2 (ja) 2013-06-19
EP2038260A1 (en) 2009-03-25

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