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Priority claimed from GB0618195Aexternal-prioritypatent/GB0618195D0/en
Priority claimed from GB0619090Aexternal-prioritypatent/GB0619090D0/en
Priority claimed from PCT/EP2006/010439external-prioritypatent/WO2008009309A1/en
Priority claimed from GB0623218Aexternal-prioritypatent/GB0623218D0/en
Priority claimed from GB0623865Aexternal-prioritypatent/GB0623865D0/en
Priority claimed from GB0625453Aexternal-prioritypatent/GB0625453D0/en
Application filed by Glaxosmithkline Biolog SafiledCriticalGlaxosmithkline Biolog Sa
Publication of SG139618A1publicationCriticalpatent/SG139618A1/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Abstract
INFLUENZA VACCINE The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent. Figure 2A.
monovalent influenza vaccine composition, kit, method for producing an influenza vaccine composition for a pandemic or prepandemic situation, and uses of an influenza virus antigen or antigen preparation thereof and an adjuvant in an oil-in-water emulsion, a pandemic influenza virus antigen or antigen preparation of the influenza virus hemagglutinin antigen, a pandemic influenza virus or antigenic preparation thereof, and an oil-in-emulsion adjuvant water and an antigen or antigen preparation of a first strain of influenza
immunogenic composition, vaccine, method for treating or preventing disease, and for preparing the immunogenic composition or vaccine, use of the vaccine, and pharmaceutical composition.