SG11202003800YA - Zika vaccines and immunogenic compositions, and methods of using the same - Google Patents
Zika vaccines and immunogenic compositions, and methods of using the sameInfo
- Publication number
- SG11202003800YA SG11202003800YA SG11202003800YA SG11202003800YA SG11202003800YA SG 11202003800Y A SG11202003800Y A SG 11202003800YA SG 11202003800Y A SG11202003800Y A SG 11202003800YA SG 11202003800Y A SG11202003800Y A SG 11202003800YA SG 11202003800Y A SG11202003800Y A SG 11202003800YA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- same
- immunogenic compositions
- zika vaccines
- zika
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24071—Demonstrated in vivo effect
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24163—Methods of inactivation or attenuation by chemical treatment
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24164—Methods of inactivation or attenuation by serial passage
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762581500P | 2017-11-03 | 2017-11-03 | |
US201762592995P | 2017-11-30 | 2017-11-30 | |
PCT/US2018/059219 WO2019090228A2 (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202003800YA true SG11202003800YA (en) | 2020-05-28 |
Family
ID=64427224
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202003949TA SG11202003949TA (en) | 2017-11-03 | 2018-11-05 | Method for inactivating zika virus and for determining the completeness of inactivation |
SG11202003796XA SG11202003796XA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
SG11202003800YA SG11202003800YA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202003949TA SG11202003949TA (en) | 2017-11-03 | 2018-11-05 | Method for inactivating zika virus and for determining the completeness of inactivation |
SG11202003796XA SG11202003796XA (en) | 2017-11-03 | 2018-11-05 | Zika vaccines and immunogenic compositions, and methods of using the same |
Country Status (12)
Country | Link |
---|---|
US (6) | US11730802B2 (en) |
EP (3) | EP3703740A2 (en) |
JP (4) | JP7295124B2 (en) |
KR (3) | KR20200083571A (en) |
CN (3) | CN111511395B (en) |
AU (6) | AU2018359558C1 (en) |
BR (3) | BR112020008652A2 (en) |
CA (3) | CA3081581A1 (en) |
MX (3) | MX2020004542A (en) |
MY (2) | MY194449A (en) |
SG (3) | SG11202003949TA (en) |
WO (3) | WO2019090238A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111511395B (en) | 2017-11-03 | 2024-10-15 | 武田疫苗股份有限公司 | Methods for inactivating Zika virus and for determining completeness of inactivation |
AU2018375173B2 (en) * | 2017-11-30 | 2022-08-25 | Takeda Vaccines, Inc. | Zika vaccines and immunogenic compositions, and methods of using the same |
JP2022533550A (en) * | 2019-05-08 | 2022-07-25 | タケダ ワクチン,インコーポレイテッド | Inactivated virus composition and Zika vaccine formulation |
EP3892260A1 (en) * | 2020-04-10 | 2021-10-13 | Bayer Animal Health GmbH | Immunostimulatory compositions based on liposomes with zwiterionic and cationic lipids |
WO2021236845A1 (en) | 2020-05-20 | 2021-11-25 | Takeda Vaccines, Inc. | Method for detection of zika virus specific antibodies |
EP4226155A1 (en) | 2020-10-09 | 2023-08-16 | Takeda Vaccines, Inc. | Methods for determining complement-fixing antibodies |
CN112980805B (en) * | 2021-02-25 | 2022-11-08 | 中国科学院广州生物医药与健康研究院 | Recombinant Zika virus attenuated strain and preparation method and application thereof |
CN112941201B (en) * | 2021-03-01 | 2022-03-08 | 武汉珈创生物技术股份有限公司 | Mixed primer for multi-cell species identification and cross contamination detection and use method thereof |
WO2023154043A1 (en) | 2022-02-09 | 2023-08-17 | Takeda Vaccines, Inc. | Zika vaccines and immunogenic compositions, and methods of using the same |
KR102619184B1 (en) * | 2022-12-27 | 2023-12-29 | 주식회사 그린백스 | Vaccine composition comprising Zika virus inactivated by Epigallocatechin-3-gallate as an active ingredient |
Family Cites Families (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3238190A (en) | 1963-10-23 | 1966-03-01 | Madaus & Co K G Fa Dr | Aescin recovery |
US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US5278302A (en) | 1988-05-26 | 1994-01-11 | University Patents, Inc. | Polynucleotide phosphorodithioates |
EP0382271B1 (en) | 1989-02-04 | 1994-12-21 | Akzo Nobel N.V. | Tocols as adjuvant in vaccine |
CA2017507C (en) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
FR2649013B1 (en) | 1989-07-03 | 1991-10-25 | Seppic Sa | VACCINES AND VECTORS OF FLUID ACTIVE INGREDIENTS CONTAINING METABOLIZABLE OIL |
FR2649012B1 (en) | 1989-07-03 | 1991-10-25 | Seppic Sa | INJECTABLE MULTIPHASIC EMULSIONS |
EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
US5776468A (en) | 1993-03-23 | 1998-07-07 | Smithkline Beecham Biologicals (S.A.) | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
WO1995026204A1 (en) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
ATE328890T1 (en) | 1994-07-15 | 2006-06-15 | Univ Iowa Res Found | IMMUNOMODULATORY OLIGONUCLEOTIDES |
US5666153A (en) | 1995-10-03 | 1997-09-09 | Virtual Shopping, Inc. | Retractable teleconferencing apparatus |
DE19612966B4 (en) | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK cells and methods of propagating influenza viruses |
DE19612967A1 (en) | 1996-04-01 | 1997-10-02 | Behringwerke Ag | Process for the propagation of influenza viruses in cell culture, and the influenza viruses obtainable by the process |
JP4012252B2 (en) | 1996-06-18 | 2007-11-21 | アルザ コーポレイション | Device for enhancing transdermal release or sampling of drugs |
US5856462A (en) | 1996-09-10 | 1999-01-05 | Hybridon Incorporated | Oligonucleotides having modified CpG dinucleosides |
US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
CN1133472C (en) | 1996-12-20 | 2004-01-07 | 阿尔萨公司 | Device and method for enhancing transdermal agent flux |
AT405939B (en) * | 1997-02-24 | 1999-12-27 | Immuno Ag | METHOD FOR INACTIVATING LIPID-ENVIRONED VIRUSES |
US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
US6309650B1 (en) | 1997-08-28 | 2001-10-30 | Cheil Jedang Corporation | Attenuated Japanese encephalitis virus adapted to Vero cell and a Japanese encephalitis vaccine |
GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
DE69815692T2 (en) | 1997-09-05 | 2004-04-29 | Glaxosmithkline Biologicals S.A. | OIL IN WATER EMULSIONS WITH SAPONINES |
CA2305785A1 (en) | 1997-10-07 | 1999-04-15 | University Of Maryland Biotechnology Institute | Method for introducing and expressing rna in animal cells |
JP2001524533A (en) | 1997-12-02 | 2001-12-04 | パウダージェクト ヴァクシンズ,インコーポレイテッド | Transdermal delivery of particulate vaccine compositions |
GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
IL138000A0 (en) | 1998-04-09 | 2001-10-31 | Smithkline Beecham Biolog | Adjuvant compositions |
DK1104306T3 (en) | 1998-08-10 | 2006-05-22 | Antigenics Inc | Preparations of CpG and Saponin Adjuvants and Methods for Using Them |
NZ511449A (en) | 1998-12-02 | 2004-05-28 | Univ Maryland | Plasmid maintenance system for antigen delivery |
US6492169B1 (en) | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
EP1103610A1 (en) | 1999-11-26 | 2001-05-30 | Introgene B.V. | Production of vaccines from immortalised mammalian cell lines |
US7472098B2 (en) | 2000-02-14 | 2008-12-30 | Ubs Financial Services, Inc. | System and method for execution of trades made pursuant to stock option and purchase plans |
CA2430322A1 (en) | 2000-11-22 | 2002-10-24 | University Of Maryland, Baltimore | Use of clya hemolysin for excretion of proteins |
GB0326439D0 (en) | 2003-11-13 | 2003-12-17 | Imp College Innovations Ltd | Methods |
BRPI0419023A (en) | 2004-08-27 | 2007-12-11 | Panacea Biotec Ltd | inactivated polio vaccine derived from the genus sabin of poliovirus |
RS51665B (en) | 2004-09-09 | 2011-10-31 | Novartis Vaccines And Diagnostics Gmbh. | Decreasing potential iatrogenic risks associated with influenza vaccines |
EP1724338A1 (en) | 2005-05-19 | 2006-11-22 | Crucell Holland B.V. | Methods for the production of a whole-inactivated West Nile Virus vaccine |
US8865184B2 (en) | 2006-09-01 | 2014-10-21 | Bharat Biotech International Limited | Vaccine for chikungunya virus infection |
US8741311B2 (en) | 2009-03-27 | 2014-06-03 | Academia Sinica | Methods and compositions for immunization against virus |
CN101954076A (en) | 2009-04-27 | 2011-01-26 | 免疫制剂美国公司 | The immunotherapy of autoimmune hepatitis and prevention |
US20140112953A1 (en) | 2011-05-26 | 2014-04-24 | Glaxo Smithkline Biologicals Sa | Inactivated dengue virus vaccine |
EP2720715B1 (en) | 2011-06-17 | 2017-08-09 | Bharat Biotech International Limited | Vaccine composition comprising an inactivated chikungunya virus strain |
DK2788023T3 (en) | 2011-12-06 | 2016-12-19 | Valneva Austria Gmbh | Aluminum compounds for use in therapeutics and vaccines |
ES2750366T3 (en) | 2012-03-08 | 2020-03-25 | Glaxosmithkline Biologicals Sa | In vitro potency assay for protein-based meningococcal vaccines |
CN104159603A (en) | 2012-03-08 | 2014-11-19 | 诺华股份有限公司 | Combination vaccines with tlr4 agonists |
US9895437B2 (en) | 2012-04-18 | 2018-02-20 | Valneva Austria Gmbh | Aluminum compounds for use in therapeutics and vaccines |
AU2014338520B2 (en) | 2013-09-14 | 2019-12-05 | Bharat Biotech International Limited | A viral vaccine and methods of manufacture thereof |
EP3194595A4 (en) | 2014-09-17 | 2018-06-20 | University of Iowa Research Foundation | Viral rna segments as immunomodulatory agents and vaccine components |
JP6755243B2 (en) | 2014-10-07 | 2020-09-16 | セラム インスティチュート オブ インディア プライベイト リミテッド | Improved methods for enterovirus inactivation and adjuvant adsorption, and the resulting dose-reducing vaccine compositions. |
MA40920A (en) | 2014-11-07 | 2017-09-12 | Takeda Vaccines Inc | VACCINES OF THE HAND, FOOT AND MOUTH, AND METHODS OF MANUFACTURING AND USE THEREOF |
US10086061B2 (en) | 2015-03-11 | 2018-10-02 | The United States Of America, As Represented By The Secretary Of The Army, On Behalf Of The Walter Reed Army Institute Of Research | Combination purified inactivated vaccine for flaviviruses |
CN108472353A (en) | 2015-06-22 | 2018-08-31 | 哈佛大学校长及研究员协会 | Composition and method for adjusting virus infection |
EA035921B1 (en) * | 2015-07-16 | 2020-08-31 | Бхарат Байотек Интернэшнл Лимитед | Vaccine compositions for prophylaxis of arbovirus infections |
US11007260B2 (en) | 2015-07-21 | 2021-05-18 | Modernatx, Inc. | Infectious disease vaccines |
WO2017056094A1 (en) | 2015-09-30 | 2017-04-06 | Ramot At Tel-Aviv University Ltd. | Attenuated virus mutated at sites of evolutionarily conserved rna structure |
WO2017070624A1 (en) | 2015-10-22 | 2017-04-27 | Modernatx, Inc. | Tropical disease vaccines |
SG11201805120YA (en) * | 2015-12-23 | 2018-07-30 | Valneva Austria Gmbh | Zika virus vaccine |
EP3184119A1 (en) | 2015-12-23 | 2017-06-28 | Themis Bioscience GmbH | Chromatography based purification strategies for measles scaffold based viruses |
US11434259B2 (en) | 2016-01-25 | 2022-09-06 | Iogenetics, Llc | Modified Zika virus NS1 protein with reduced cross-reactive immunogenicity |
SG10201913630YA (en) * | 2016-02-17 | 2020-03-30 | Curevac Ag | Zika virus vaccine |
CN109152826B (en) | 2016-02-25 | 2022-11-04 | 宾夕法尼亚大学理事会 | Novel vaccine against Zika virus |
US20170354729A1 (en) | 2016-03-16 | 2017-12-14 | Novavax, Inc. | Vaccine compositions containing modified zika virus antigens |
CN105749268B (en) | 2016-04-11 | 2020-09-11 | 北京科兴中维生物技术有限公司 | Inactivated Zika virus vaccine |
WO2017181098A2 (en) | 2016-04-15 | 2017-10-19 | Visterra, Inc. | Antibody molecules to zika virus and uses thereof |
WO2017192856A1 (en) | 2016-05-04 | 2017-11-09 | University Of Miami | Zika virus vector for treating zika virus infection |
EP3454894B1 (en) | 2016-05-10 | 2022-07-27 | Najit Technologies, Inc. | Inactivating pathogens and producing highly immunogenic inactivated vaccines using a dual oxidation process |
US11033615B2 (en) | 2016-05-31 | 2021-06-15 | The Government of the United States, As Represented by the Secretary of the Army Fort Detrick, Maryland | Zika virus vaccine and methods of production |
EP3463445A1 (en) | 2016-06-02 | 2019-04-10 | GlaxoSmithKline Biologicals SA | Zika viral antigen constructs |
US10611801B2 (en) | 2016-06-09 | 2020-04-07 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods for preventing and treating Zika virus infection |
GB201610162D0 (en) | 2016-06-10 | 2016-07-27 | Imp Innovations Ltd And Inst Pasteur | Methods |
CA3026807A1 (en) | 2016-06-13 | 2017-12-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acids encoding zika virus-like particles and their use in zika virus vaccines and diagnostic assays |
WO2018009603A1 (en) | 2016-07-08 | 2018-01-11 | The United State of America, as represented by the Secretary, Department of Health and Human Service | Chimeric west nile/zika viruses and methods of use |
EP3481848B1 (en) | 2016-07-08 | 2021-02-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Genomic sequences encoding for an attenuated mutant zika virus |
WO2018022786A1 (en) | 2016-07-26 | 2018-02-01 | Washington University | Antibodies to zika virus and methods of use thereof |
GB201613191D0 (en) | 2016-07-29 | 2016-09-14 | Univ Oxford Innovation Ltd | Zika virus vaccine |
BE1025121B1 (en) | 2016-11-17 | 2018-11-05 | Glaxosmithkline Biologicals Sa | ANTIGENIC CONSTRUCTS OF ZIKA VIRUS |
EP3558353A2 (en) | 2016-12-23 | 2019-10-30 | Expres2ion Biotechnologies ApS | New flavivirus vaccine |
CN108503697B (en) | 2017-02-27 | 2023-03-31 | 中国科学院上海巴斯德研究所 | Zika virus subunit vaccine expressed by drosophila cells |
CN108503696B (en) | 2017-02-27 | 2023-05-12 | 中国科学院上海巴斯德研究所 | Zika virus subunit vaccine expressed by yeast cells |
US11655471B2 (en) | 2017-03-08 | 2023-05-23 | University Of Georgia Research Foundation, Inc. | Engineered cells with decreased gene expression resulting in increased viral production |
WO2018187799A1 (en) | 2017-04-07 | 2018-10-11 | The Rockefeller University | Compositions and methods related to human neutralizing antibodies to zika and dengue 1 virus |
CN109081868B (en) | 2017-06-14 | 2022-06-24 | 中国科学院上海巴斯德研究所 | Monoclonal antibody targeting Zika virus envelope protein conserved epitope and application thereof |
WO2018237039A1 (en) | 2017-06-20 | 2018-12-27 | Texas Tech University System | Zika virus like particle (vlp) based vaccine and microneutralization assay |
EP3417943B1 (en) | 2017-06-21 | 2020-02-12 | Eppendorf AG | Centrifuge rotor with seal |
CN107188935B (en) | 2017-07-20 | 2018-10-02 | 北京健乃喜生物技术有限公司 | A kind of zika virus NS1 antigenic mutants and its application |
WO2019042555A1 (en) | 2017-08-31 | 2019-03-07 | Humabs Biomed Sa | Multispecific antibodies specifically binding to zika virus epitopes and uses thereof |
CN107537029B (en) | 2017-09-14 | 2021-03-19 | 北京科兴生物制品有限公司 | Zika virus and yellow fever virus combined inactivated vaccine |
GB201716254D0 (en) | 2017-10-05 | 2017-11-22 | Univ Leuven Kath | Live-attenuated flaviruses with heterologous antigens |
CN111511395B (en) | 2017-11-03 | 2024-10-15 | 武田疫苗股份有限公司 | Methods for inactivating Zika virus and for determining completeness of inactivation |
BR102017024030A2 (en) | 2017-11-08 | 2019-06-04 | Universidade Federal De São João Del Rei | IMMUNOGENIC RECOMBINANT PROTEIN WITH ZIKA ANTIGENS FOR VACCINE VIRUS AND ITS USES |
US20210054055A1 (en) | 2017-11-21 | 2021-02-25 | The University Of Vermont And State Agricultural College | Highly specific zika neutralizing human antibodies |
AU2018375173B2 (en) | 2017-11-30 | 2022-08-25 | Takeda Vaccines, Inc. | Zika vaccines and immunogenic compositions, and methods of using the same |
CN108187036A (en) | 2017-12-08 | 2018-06-22 | 北京科兴中维生物技术有限公司 | A kind of zika virus combines inactivated vaccine with encephalitis B virus |
CN108210921A (en) | 2017-12-29 | 2018-06-29 | 广州恩宝生物医药科技有限公司 | A kind of zika virus vaccine and preparation method thereof |
EP3755818A1 (en) | 2018-02-22 | 2020-12-30 | Nano4 Global, Lda | Method for detecting flaviviridae |
EP3762021A4 (en) | 2018-03-08 | 2022-01-26 | Codagenix Inc. | Attenuated flaviviruses |
BR112020019719A2 (en) | 2018-03-29 | 2021-01-26 | Emergex Vaccines Holding Limited | vaccine compositions |
KR102075581B1 (en) | 2018-04-27 | 2020-02-10 | 가톨릭대학교 산학협력단 | Adjuvant comprising nucleic acid molecule inserted viral expression regulation sequence and phamraceutical composition having the adjuvant |
WO2020017765A1 (en) | 2018-07-18 | 2020-01-23 | (주)진매트릭스 | Zika virus variant and zika vaccine composition comprising same |
US20220118077A1 (en) | 2018-09-11 | 2022-04-21 | Shanghai Public Health Clinical Center | Immunogen for broad-spectrum influenza vaccine and application thereof |
EP3870208A4 (en) | 2018-10-26 | 2022-10-26 | New York Blood Center, Inc. | Zika virus immunogenic compositions |
JP7463366B2 (en) | 2018-11-20 | 2024-04-08 | タケダ ワクチン,インコーポレイテッド | Novel anti-Zika virus antibodies and uses thereof |
JP2022533550A (en) | 2019-05-08 | 2022-07-25 | タケダ ワクチン,インコーポレイテッド | Inactivated virus composition and Zika vaccine formulation |
US20230272405A1 (en) | 2020-06-22 | 2023-08-31 | University Of Connecticut | Flavivirus signal peptides, vaccine constructs, and methods therefor |
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