SG11201907674WA - Ligand bound mbp membranes, uses and method of manufacturing - Google Patents

Ligand bound mbp membranes, uses and method of manufacturing

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Publication number
SG11201907674WA
SG11201907674WA SG11201907674WA SG11201907674WA SG11201907674WA SG 11201907674W A SG11201907674W A SG 11201907674WA SG 11201907674W A SG11201907674W A SG 11201907674WA SG 11201907674W A SG11201907674W A SG 11201907674WA SG 11201907674W A SG11201907674W A SG 11201907674WA
Authority
SG
Singapore
Prior art keywords
international
technologies
membranes
terapore
bold
Prior art date
Application number
SG11201907674WA
Inventor
Rachel M Dorin
Spencer Robbins
Mark Hurwitz
Original Assignee
Terapore Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terapore Tech Inc filed Critical Terapore Tech Inc
Publication of SG11201907674WA publication Critical patent/SG11201907674WA/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • GPHYSICS
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
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    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
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    • B01D67/0002Organic membrane manufacture
    • B01D67/0006Organic membrane manufacture by chemical reactions
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    • B01D67/0002Organic membrane manufacture
    • B01D67/0023Organic membrane manufacture by inducing porosity into non porous precursor membranes
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    • B01D67/0081After-treatment of organic or inorganic membranes
    • B01D67/0093Chemical modification
    • B01D67/00931Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
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    • B01D69/02Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
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    • B01D69/14Dynamic membranes
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    • B01D69/142Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers"
    • B01D69/144Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers" containing embedded or bound biomolecules
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    • B01D71/06Organic material
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    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078Pore diameter
    • B01J20/28085Pore diameter being more than 50 nm, i.e. macropores
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    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28088Pore-size distribution
    • B01J20/28092Bimodal, polymodal, different types of pores or different pore size distributions in different parts of the sorbent
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
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    • B01J20/3206Organic carriers, supports or substrates
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    • B01J20/321Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
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    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • B01J20/3212Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
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    • B01J20/3214Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
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    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
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    • B01J20/3268Macromolecular compounds
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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    • C12N15/09Recombinant DNA-technology
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    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • BPERFORMING OPERATIONS; TRANSPORTING
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Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 30 August 2018 (30.08.2018) W I P0 I P C T Iiiimmomiolollmoliolomonnomilomomflovoiml (10) International Publication Number WO 2018/156731 Al (51) International Patent Classification: BOlD 61/36 (2006.01) C07C 7/144 (2006.01) BOlD 71/80 (2006.01) (21) International Application Number: PCT/US2018/019173 (22) International Filing Date: 22 February 2018 (22.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/462,161 22 February 2017 (22.02.2017) US (72) Inventors; and (71) Applicants: DORIN, Rachel M. [US/US]; c/o TeraPore Technologies, Inc., 407 Cabot Road, San Francisco, Cali- fornia 12065 (US). ROBBINS, Spencer [US/US]; c/o Ter- aPore Technologies, Inc., 407 Cabot Road, San Francisco, California 12065 (US). HURWITZ, Mark [US/US]; c/o TeraPore Technologies, Inc., 407 Cabot Road, San Francis- co, California 12065 (US). (74) Agent: DOSHI, Dipu; Blank Rome LLP, 1825 Eye Street, NW, Washington, District of Columbia 20006 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: LIGAND BOUND MBP MEMBRANES, USES AND METHOD OF MANUFACTURING 1-1 FIG. 1 (57) : Compositions and methods are described for self-assembled polymer materials having at least one of macro, meso, or 5 micro pores.
SG11201907674WA 2017-02-22 2018-02-22 Ligand bound mbp membranes, uses and method of manufacturing SG11201907674WA (en)

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US20200232978A1 (en) 2020-07-23
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KR20190137789A (en) 2019-12-11
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EP3585506A1 (en) 2020-01-01
KR102308806B1 (en) 2021-10-07
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EP3585506A4 (en) 2021-01-13
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MX2019010056A (en) 2019-10-09
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