SG11201705475QA - Fcrn antibodies and methods of use thereof - Google Patents
Fcrn antibodies and methods of use thereofInfo
- Publication number
- SG11201705475QA SG11201705475QA SG11201705475QA SG11201705475QA SG11201705475QA SG 11201705475Q A SG11201705475Q A SG 11201705475QA SG 11201705475Q A SG11201705475Q A SG 11201705475QA SG 11201705475Q A SG11201705475Q A SG 11201705475QA SG 11201705475Q A SG11201705475Q A SG 11201705475QA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- fcrn antibodies
- fcrn
- antibodies
- Prior art date
Links
- 101150050927 Fcgrt gene Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/06—Antipsoriatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Nutrition Science (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562110071P | 2015-01-30 | 2015-01-30 | |
US201562258082P | 2015-11-20 | 2015-11-20 | |
PCT/US2016/015720 WO2016123521A2 (en) | 2015-01-30 | 2016-01-29 | Fcrn antibodies and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201705475QA true SG11201705475QA (en) | 2017-08-30 |
Family
ID=56544538
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202007232WA SG10202007232WA (en) | 2015-01-30 | 2016-01-29 | Fcrn antibodies and methods of use thereof |
SG11201705475QA SG11201705475QA (en) | 2015-01-30 | 2016-01-29 | Fcrn antibodies and methods of use thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202007232WA SG10202007232WA (en) | 2015-01-30 | 2016-01-29 | Fcrn antibodies and methods of use thereof |
Country Status (21)
Country | Link |
---|---|
US (3) | US10676526B2 (en) |
EP (2) | EP4286011A3 (en) |
JP (2) | JP6853178B2 (en) |
KR (2) | KR102483016B1 (en) |
CN (13) | CN118667015A (en) |
AU (1) | AU2016211280B2 (en) |
CA (1) | CA2972822A1 (en) |
DK (1) | DK3250610T3 (en) |
ES (1) | ES2962824T3 (en) |
FI (1) | FI3250610T3 (en) |
HR (1) | HRP20231399T1 (en) |
HU (1) | HUE063778T2 (en) |
IL (1) | IL252837B (en) |
LT (1) | LT3250610T (en) |
NZ (1) | NZ733097A (en) |
PL (1) | PL3250610T3 (en) |
PT (1) | PT3250610T (en) |
RS (1) | RS64768B1 (en) |
SG (2) | SG10202007232WA (en) |
SI (1) | SI3250610T1 (en) |
WO (1) | WO2016123521A2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2934644C (en) | 2013-12-24 | 2023-11-21 | Argen-X N.V. | Fcrn antagonists and methods of use |
CA2946430A1 (en) * | 2014-06-12 | 2015-12-17 | F. Hoffmann-La Roche Ag | Method for selecting antibodies with modified fcrn interaction |
US10676526B2 (en) | 2015-01-30 | 2020-06-09 | Momenta Pharmaceuticals, Inc. | FcRn antibodies and methods of use thereof |
CN109790221B (en) * | 2016-07-29 | 2023-12-26 | 动量制药公司 | FcRN antibodies and methods of use thereof |
RU2020100880A (en) * | 2017-06-15 | 2021-07-15 | Юсб Биофарма Срл | METHOD FOR TREATMENT OF IMMUNE THROMBOCYTOPENIA |
KR20200098604A (en) | 2017-12-13 | 2020-08-20 | 모멘타 파머슈티컬스 인코포레이티드 | FcRn antibodies and methods of use thereof |
MX2020013195A (en) | 2018-06-08 | 2021-02-26 | Argenx Bvba | Compositions and methods for treating immune thrombocytopenia. |
JOP20210014A1 (en) * | 2018-07-20 | 2021-01-19 | Zhongli Zhang | Compositions of fcrn antibodies and methods of use thereof |
WO2020018910A1 (en) * | 2018-07-20 | 2020-01-23 | Momenta Pharmaceuticals, Inc. | Fcrn antibody compositions |
US20220144941A1 (en) | 2018-10-16 | 2022-05-12 | UCB Biopharma SRL | Method for the treatment of myasthenia gravis |
JP7565951B2 (en) | 2019-06-07 | 2024-10-11 | アルジェニクス ビーブイ | Pharmaceutical formulations of FcRn inhibitors suitable for subcutaneous administration |
MX2022001380A (en) * | 2019-08-01 | 2022-03-25 | Momenta Pharmaceuticals Inc | Fcrn antibodies and methods of use thereof. |
IL292889A (en) * | 2019-11-19 | 2022-07-01 | Immunovant Sciences Gmbh | Methods of treating warm autoimmune hemolytic anemia using anti-fcrn antibodies |
MX2023005313A (en) * | 2020-11-06 | 2023-07-11 | Momenta Pharmaceuticals Inc | Fcrn antibodies and methods of use thereof. |
EP4287828A1 (en) * | 2021-02-02 | 2023-12-13 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric fcrn |
CN116234827A (en) * | 2021-09-03 | 2023-06-06 | 舒泰神(北京)生物制药股份有限公司 | Antibodies specifically recognizing FcRn and uses thereof |
AU2023281650A1 (en) | 2022-05-30 | 2024-10-17 | Hanall Biopharma Co., Ltd. | Anti-fcrn antibody or antigen binding fragment thereof with improved stability |
WO2024163894A1 (en) | 2023-02-04 | 2024-08-08 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating hemolytic disease of the fetus and newborn |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4364645B2 (en) | 2002-02-14 | 2009-11-18 | 中外製薬株式会社 | Antibody-containing solution formulation |
EP1660128A4 (en) * | 2003-08-08 | 2009-01-21 | Univ New York State Res Found | Anti-fcrn antibodies for treatment of auto/allo immune conditions |
US7662928B2 (en) | 2003-08-08 | 2010-02-16 | The Research Foundation Of State University Of New York | Anti-FcRn antibodies for treatment of auto/allo immune conditions |
CN101124245A (en) * | 2003-11-12 | 2008-02-13 | 比奥根艾迪克Ma公司 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto |
NZ561137A (en) | 2005-03-08 | 2011-09-30 | Pharmacia & Upjohn Co Llc | Stable anti-CTLA-4 antibody compositions with chelating agents |
CA2637929A1 (en) | 2006-01-25 | 2007-08-02 | The Research Foundation Of State University Of New York | Anti-fcrn antibodies for treatement of auto/allo immune conditions |
CN101421297A (en) * | 2006-02-17 | 2009-04-29 | 森托尼克斯制药有限公司 | Peptides that block the binding of igg to fcrn |
CA2644405A1 (en) * | 2006-03-13 | 2007-09-20 | Ablynx N.V. | Amino acid sequences directed against il-6 and polypeptides comprising the same for the treatment of diseases and disorders associated with il-6-mediated signalling |
NZ589451A (en) * | 2008-04-25 | 2012-07-27 | Dyax Corp | Antibodies against fcrn and use thereof |
WO2011008517A2 (en) * | 2009-06-30 | 2011-01-20 | Research Development Foundation | Immunoglobulin fc polypeptides |
AU2012262007B2 (en) * | 2011-06-02 | 2017-06-22 | Takeda Pharmaceutical Company Limited | Fc receptor binding proteins |
GB201208370D0 (en) | 2012-05-14 | 2012-06-27 | Ucb Pharma Sa | Antibodies |
US20130323242A1 (en) | 2012-06-01 | 2013-12-05 | Ophthotech Corp. | Compositions comprising an anti-pdgf aptamer and a vegf antagonist |
EP2934587A4 (en) | 2012-12-18 | 2016-08-03 | Merck Sharp & Dohme | Liquid formulations for an anti-tnf alpha antibody |
EP3719122A1 (en) | 2013-05-02 | 2020-10-07 | Momenta Pharmaceuticals, Inc. | Sialylated glycoproteins |
KR101815265B1 (en) | 2013-06-20 | 2018-01-04 | 한올바이오파마주식회사 | FcRn specific human antibody and composition for treatment of autoimmune diseases |
US10676526B2 (en) | 2015-01-30 | 2020-06-09 | Momenta Pharmaceuticals, Inc. | FcRn antibodies and methods of use thereof |
US20160264669A1 (en) * | 2015-03-09 | 2016-09-15 | Argen-X N.V. | Methods of reducing serum levels of fc-containing agents using fcrn antagonists |
WO2016183352A1 (en) | 2015-05-12 | 2016-11-17 | Syntimmune, Inc. | Humanized affinity matured anti-fcrn antibodies |
CN109790221B (en) | 2016-07-29 | 2023-12-26 | 动量制药公司 | FcRN antibodies and methods of use thereof |
WO2019110823A1 (en) | 2017-12-08 | 2019-06-13 | Argenx Bvba | Use of fcrn antagonists for treatment of generalized myasthenia gravis |
KR20200098604A (en) | 2017-12-13 | 2020-08-20 | 모멘타 파머슈티컬스 인코포레이티드 | FcRn antibodies and methods of use thereof |
JOP20210014A1 (en) | 2018-07-20 | 2021-01-19 | Zhongli Zhang | Compositions of fcrn antibodies and methods of use thereof |
WO2020018910A1 (en) | 2018-07-20 | 2020-01-23 | Momenta Pharmaceuticals, Inc. | Fcrn antibody compositions |
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2016
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- 2016-01-29 CN CN202410661138.XA patent/CN118652337A/en active Pending
- 2016-01-29 SG SG11201705475QA patent/SG11201705475QA/en unknown
- 2016-01-29 FI FIEP16744204.5T patent/FI3250610T3/en active
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