SG10201702437XA - A Detection Method - Google Patents

A Detection Method

Info

Publication number
SG10201702437XA
SG10201702437XA SG10201702437XA SG10201702437XA SG10201702437XA SG 10201702437X A SG10201702437X A SG 10201702437XA SG 10201702437X A SG10201702437X A SG 10201702437XA SG 10201702437X A SG10201702437X A SG 10201702437XA SG 10201702437X A SG10201702437X A SG 10201702437XA
Authority
SG
Singapore
Prior art keywords
hfmd
detecting
detection method
mirna
subjects
Prior art date
Application number
SG10201702437XA
Inventor
Chu Jang Hann Justin
Min Nyo
Original Assignee
Agency Science Tech & Res
Nat Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res, Nat Univ Singapore filed Critical Agency Science Tech & Res
Priority to SG10201702437XA priority Critical patent/SG10201702437XA/en
Priority to CN201880022278.5A priority patent/CN110475872B/en
Priority to SG11201903422WA priority patent/SG11201903422WA/en
Priority to PCT/SG2018/050134 priority patent/WO2018174830A1/en
Publication of SG10201702437XA publication Critical patent/SG10201702437XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A DETECTION METHOD The present invention relates to a method of detecting Hand-Foot-and-Mouth Disease (HFMD) in subjects. In particular, the method relates to detecting promising biomarkers in the saliva of these subjects. In an aspect of the present invention, there is provided a method for detecting HFMD, the method comprising determining the presence of a miRNA in a saliva sample, wherein the presence of the miRNA in the saliva sample is indicative of HFMD. (Figure 10)
SG10201702437XA 2017-03-24 2017-03-24 A Detection Method SG10201702437XA (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SG10201702437XA SG10201702437XA (en) 2017-03-24 2017-03-24 A Detection Method
CN201880022278.5A CN110475872B (en) 2017-03-24 2018-03-26 Detection method
SG11201903422WA SG11201903422WA (en) 2017-03-24 2018-03-26 A detection method
PCT/SG2018/050134 WO2018174830A1 (en) 2017-03-24 2018-03-26 A detection method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG10201702437XA SG10201702437XA (en) 2017-03-24 2017-03-24 A Detection Method

Publications (1)

Publication Number Publication Date
SG10201702437XA true SG10201702437XA (en) 2018-10-30

Family

ID=63584672

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201702437XA SG10201702437XA (en) 2017-03-24 2017-03-24 A Detection Method
SG11201903422WA SG11201903422WA (en) 2017-03-24 2018-03-26 A detection method

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201903422WA SG11201903422WA (en) 2017-03-24 2018-03-26 A detection method

Country Status (3)

Country Link
CN (1) CN110475872B (en)
SG (2) SG10201702437XA (en)
WO (1) WO2018174830A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111537710B (en) * 2020-03-30 2022-12-13 瑞博奥(广州)生物科技股份有限公司 Marker combination, antibody chip and kit for detecting hand-foot-and-mouth disease
CN113977596A (en) * 2021-09-29 2022-01-28 湖北隆感科技有限公司 Detection robot and detection method for smart campus management

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143181A2 (en) * 2008-05-19 2009-11-26 The Regents Of The University Of California Micro-rna profile in human saliva and its use for detection of oral cancer
CN104073569B (en) * 2014-07-21 2016-06-22 广州市妇女儿童医疗中心 For diagnosing the molecular marked compound of hand-foot-mouth disease pole serious symptom and detection method thereof and test kit

Also Published As

Publication number Publication date
SG11201903422WA (en) 2019-05-30
WO2018174830A1 (en) 2018-09-27
CN110475872B (en) 2024-04-26
CN110475872A (en) 2019-11-19

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