SE8406263D0 - PROCEDURE FOR THE PREPARATION OF A NEW MEDICINE USEFUL HEMIN ASSOCIATION - Google Patents

PROCEDURE FOR THE PREPARATION OF A NEW MEDICINE USEFUL HEMIN ASSOCIATION

Info

Publication number
SE8406263D0
SE8406263D0 SE8406263A SE8406263A SE8406263D0 SE 8406263 D0 SE8406263 D0 SE 8406263D0 SE 8406263 A SE8406263 A SE 8406263A SE 8406263 A SE8406263 A SE 8406263A SE 8406263 D0 SE8406263 D0 SE 8406263D0
Authority
SE
Sweden
Prior art keywords
hemin
preparation
association
procedure
new medicine
Prior art date
Application number
SE8406263A
Other languages
Swedish (sv)
Other versions
SE8406263L (en
SE457958B (en
Inventor
G D Ingberg
R L A Penttile
R O Tokola
R A Tenhunen
Original Assignee
Lekemedelsfabriken Medica Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lekemedelsfabriken Medica Ab filed Critical Lekemedelsfabriken Medica Ab
Publication of SE8406263D0 publication Critical patent/SE8406263D0/en
Publication of SE8406263L publication Critical patent/SE8406263L/en
Publication of SE457958B publication Critical patent/SE457958B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A method for the preparation of a new, physiologically active, water-soluble complex compound of hemin arginate or hemin lysinate in which crystalline hemin and the amino acid L-arginine or L-lysine, in a molar proportion of 1:3, are allowed to react at room temperature under vigorous stirring for 10 to 15 hours in a solvent mixture of acetone and water 300:20 v/v. The hemin arginate or hemin lysinate thus formed is a powdery, stable compound suitable for use as raw material in tablets or capsules or as dry substance for preparation of injections for treatment of various types of anemia, particularly anemias associated with prophyria.
SE8406263A 1984-12-12 1984-12-10 WATER-SOLUBLE HEMIN ARGINATE OR HEMIN-LYSINATE SOCIETY, PROCEDURE FOR PREPARING THEREOF AND USING THEREOF FOR MANUFACTURE OF MEDICAL COMPOSITIONS SE457958B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08431398A GB2168354B (en) 1984-12-12 1984-12-12 Hemin compound

Publications (3)

Publication Number Publication Date
SE8406263D0 true SE8406263D0 (en) 1984-12-10
SE8406263L SE8406263L (en) 1986-06-11
SE457958B SE457958B (en) 1989-02-13

Family

ID=10571084

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8406263A SE457958B (en) 1984-12-12 1984-12-10 WATER-SOLUBLE HEMIN ARGINATE OR HEMIN-LYSINATE SOCIETY, PROCEDURE FOR PREPARING THEREOF AND USING THEREOF FOR MANUFACTURE OF MEDICAL COMPOSITIONS

Country Status (12)

Country Link
JP (1) JPH0647541B2 (en)
AT (1) AT389308B (en)
BE (1) BE901319A (en)
CA (1) CA1242713A (en)
CH (1) CH666273A5 (en)
DE (1) DE3446887C2 (en)
FR (1) FR2574662B1 (en)
GB (1) GB2168354B (en)
LU (1) LU85716A1 (en)
NL (1) NL192682C (en)
SE (1) SE457958B (en)
SU (1) SU1384188A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0645681B2 (en) * 1986-02-05 1994-06-15 美浜 久春 Modified hem
IT1245890B (en) * 1991-04-12 1994-10-25 Alfa Wassermann Spa PHARMACEUTICAL FORMULATIONS FOR ORAL USE GASTRORESANTS CONTAINING BILE ACIDS.
US7994217B2 (en) 2002-05-02 2011-08-09 Xanodyne Pharmaceuticals, Inc. Prenatal multivitamin/multimineral supplement
RU2611636C1 (en) * 2016-02-25 2017-02-28 Федеральное государственное бюджетное образовательное учреждение высшего образования Новосибирский государственный аграрный университет Hematogen
RU2671633C1 (en) * 2017-11-30 2018-11-06 Общество с ограниченной ответственностью "ОКТАВА ХОЛДИНГ" Highly effective hematogen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2912M (en) * 1963-07-24 1964-11-09 Rech S Pharma E R P H A R Soc Procaine hematoporphyrinate dihydrochloride.
JPS4930521A (en) * 1972-07-17 1974-03-19
JPS5144623A (en) * 1974-10-14 1976-04-16 Green Cross Corp CHUSHAYOASECHIRUSARICHIRUSANENNO SEIHO
DE2527158A1 (en) * 1975-06-18 1976-12-23 Herz Eberhard MEDICINAL PRODUCTS FOR THE TREATMENT OF INFECTIOUS DISEASES AND INFLAMMATION IN HUMAN AND VETERINAL MEDICINE THAT CANNOT BE DETECTED BY MICROORGANISMS
JPS6021570B2 (en) * 1978-07-04 1985-05-28 三共株式会社 Method for manufacturing high concentration preparations of DOPAs
JPS5780317A (en) * 1980-11-05 1982-05-19 Sumitomo Chem Co Ltd Preparation of pharmaceutical composition for injection
JPS57209211A (en) * 1981-06-18 1982-12-22 Shiseido Co Ltd Antimicrobial composition

Also Published As

Publication number Publication date
BE901319A (en) 1985-04-16
NL192682B (en) 1997-08-01
SU1384188A3 (en) 1988-03-23
DE3446887A1 (en) 1986-07-03
JPH0647541B2 (en) 1994-06-22
DE3446887C2 (en) 1994-05-05
JPS61172821A (en) 1986-08-04
GB8431398D0 (en) 1985-01-23
SE8406263L (en) 1986-06-11
ATA390784A (en) 1989-04-15
LU85716A1 (en) 1985-07-24
FR2574662B1 (en) 1990-03-02
NL8403782A (en) 1986-07-01
NL192682C (en) 1997-12-02
AT389308B (en) 1989-11-27
FR2574662A1 (en) 1986-06-20
GB2168354A (en) 1986-06-18
SE457958B (en) 1989-02-13
CA1242713A (en) 1988-10-04
GB2168354B (en) 1988-12-07
CH666273A5 (en) 1988-07-15

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