SE8204064L - Tissue adhesive AND SET FOR ITS PREPARATION - Google Patents

Tissue adhesive AND SET FOR ITS PREPARATION

Info

Publication number
SE8204064L
SE8204064L SE8204064A SE8204064A SE8204064L SE 8204064 L SE8204064 L SE 8204064L SE 8204064 A SE8204064 A SE 8204064A SE 8204064 A SE8204064 A SE 8204064A SE 8204064 L SE8204064 L SE 8204064L
Authority
SE
Sweden
Prior art keywords
fibrinogen
factor xiii
antibiotic
tissue adhesive
preparation
Prior art date
Application number
SE8204064A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8204064D0 (en
SE459848B (en
Inventor
H Redl
T Seelich
Y Linnau
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of SE8204064D0 publication Critical patent/SE8204064D0/en
Publication of SE8204064L publication Critical patent/SE8204064L/en
Publication of SE459848B publication Critical patent/SE459848B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A tissue adhesive based on human or animal proteins contains factor XIII, fibrinogen and an antibiotic. In order to achieve a high straining capacity of the adherences and a retarded antimicrobial efficacy, the ratio of factor XIII to fibrinogen, expressed in units of factor XIII per gram of fibrinogen, amounts to at least 500. The antibiotic is chosen among amino-glucosides, beta- lactams, polypeptides or tetracyclines. In a method of producing the tissue adhesive the concentration ratio of factor XIII to fibrinogen is adjusted in a fibrinogen-containing blood plasma fraction by the addition of factor XIII. The antibiotic is added either before deepfreezing or lyophilization of the resulting preparation, or after thawing or reconstitution of the same.
SE8204064A 1981-07-28 1982-07-01 TEXTILE FILM CONTAINING FACTOR XIII, THE FIBRINOGEN AND ANTIBIOTIC, AND SUCH BEFORE ITS PREPARATION SE459848B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0333781A AT369990B (en) 1981-07-28 1981-07-28 METHOD FOR PRODUCING A TISSUE ADHESIVE

Publications (3)

Publication Number Publication Date
SE8204064D0 SE8204064D0 (en) 1982-07-01
SE8204064L true SE8204064L (en) 1983-01-29
SE459848B SE459848B (en) 1989-08-14

Family

ID=3548998

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8204064A SE459848B (en) 1981-07-28 1982-07-01 TEXTILE FILM CONTAINING FACTOR XIII, THE FIBRINOGEN AND ANTIBIOTIC, AND SUCH BEFORE ITS PREPARATION

Country Status (14)

Country Link
JP (1) JPH0696039B2 (en)
AR (1) AR227252A1 (en)
AT (1) AT369990B (en)
BE (1) BE893851A (en)
CA (1) CA1168982A (en)
CH (1) CH659187B (en)
DE (1) DE3225102A1 (en)
DK (1) DK157977C (en)
ES (1) ES514441A0 (en)
FR (1) FR2510408B1 (en)
GB (1) GB2102811B (en)
IT (1) IT1157313B (en)
NL (1) NL192665C (en)
SE (1) SE459848B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102628B2 (en) * 1984-03-27 1994-12-14 イムノ・アクチエンゲゼルシャフト Tissue adhesive manufacturing method
JPS6185304A (en) * 1984-10-01 1986-04-30 Green Cross Corp:The Auxiliary for dental treatment
DE3622642A1 (en) * 1986-07-05 1988-01-14 Behringwerke Ag ONE-COMPONENT TISSUE ADHESIVE AND METHOD FOR THE PRODUCTION THEREOF
AT397203B (en) * 1988-05-31 1994-02-25 Immuno Ag FABRIC ADHESIVE
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
NZ229385A (en) * 1989-06-01 1992-02-25 Life Technologies Inc Treatment of processed fish product (surimi) with alpha-2-macroglobulin to neutralise alkaline proteases in the fish
IT1243180B (en) * 1990-07-31 1994-05-24 Nunzio Rapisarda USE OF PHOSPHOMYCIN AND ITS SALTS AS A TOPICAL CICATRIZING AGENT
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US7208179B1 (en) 1990-11-27 2007-04-24 The American National Red Cross Methods for treating disease and forming a supplemented fibrin matrix
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
AU4566893A (en) * 1992-07-18 1994-02-14 Opperbas Holding B.V. A two component fibrin-glue composition for improving in vitro fertilization
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
JPH09502161A (en) † 1993-03-12 1997-03-04 ジ・アメリカン・ナショナル・レッド・クロス Supplemented and non-supplemented tissue sealants, methods of making and using the same
DK0691858T3 (en) * 1993-03-30 2000-05-08 Omrix Biopharm Sa Two-component fibrin glue
DE19521324C1 (en) * 1995-06-12 1996-10-31 Immuno Ag Tissue adhesive and use thereof as a hemostatic
DE19617369A1 (en) * 1996-04-30 1997-11-06 Immuno Ag Storage-stable fibrinogen preparations
AT406120B (en) 1997-08-28 2000-02-25 Immuno Ag TISSUE ADHESIVE
AT407484B (en) 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag MEDICINES FOR PROMOTING Wound Healing
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
DE60042343D1 (en) 1999-12-23 2009-07-16 Csl Ltd SEPARATION OF FIBRINOGES OF PLASMAPROTEASES
US6506365B1 (en) 2000-09-25 2003-01-14 Baxter Aktiengesellschaft Fibrin/fibrinogen binding conjugate
IL144446A0 (en) * 2001-07-19 2002-05-23 Prochon Biotech Ltd Plasma protein matrices and methods for their preparation
US20060155234A1 (en) 2002-09-10 2006-07-13 American National Red Cross Hemostatic dressing
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20080176789A1 (en) 2004-08-27 2008-07-24 Novc Nordisk Healthcare A/G Purification of Factor Xlll Polypeptides From Biological Materials
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
AU2005308830B2 (en) 2004-11-23 2012-01-19 Zymogenetics, Inc. Purification of recombinant human factor XIII
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
JP5965573B2 (en) 2006-08-04 2016-08-10 エスティービー リミテッド Solid dressing for treating wound tissue
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20090075891A1 (en) 2007-08-06 2009-03-19 Macphee Martin Methods and dressings for sealing internal injuries
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
EP4456935A1 (en) 2021-12-30 2024-11-06 Baxter International Inc. Fibrinogen and thrombin solutions for a fibrin sealant and fibrin sealant kit

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT359653B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
AT359652B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
JPS56501129A (en) * 1979-08-31 1981-08-13

Also Published As

Publication number Publication date
FR2510408A1 (en) 1983-02-04
DE3225102C2 (en) 1990-05-31
BE893851A (en) 1982-11-16
JPH0696039B2 (en) 1994-11-30
AT369990B (en) 1983-02-25
NL8202982A (en) 1983-02-16
GB2102811B (en) 1985-01-30
GB2102811A (en) 1983-02-09
ES8306023A1 (en) 1983-05-01
DK157977B (en) 1990-03-12
CH659187B (en) 1987-01-15
SE8204064D0 (en) 1982-07-01
NL192665C (en) 1997-12-02
CA1168982A (en) 1984-06-12
DE3225102A1 (en) 1983-02-17
ES514441A0 (en) 1983-05-01
JPS5826821A (en) 1983-02-17
DK157977C (en) 1990-08-13
ATA333781A (en) 1982-07-15
DK300682A (en) 1983-01-29
IT8222595A0 (en) 1982-07-27
SE459848B (en) 1989-08-14
IT1157313B (en) 1987-02-11
NL192665B (en) 1997-08-01
AR227252A1 (en) 1982-09-30
FR2510408B1 (en) 1987-02-27

Similar Documents

Publication Publication Date Title
SE8204064L (en) Tissue adhesive AND SET FOR ITS PREPARATION
SE8000470L (en) TISSUE BINDING AND PROCEDURE FOR ITS MANUFACTURING AND USING THE BINDING AGENT
DE69008423D1 (en) Dynamic fixation of porcine acid valves.
SE8000469L (en) TISSUE BINDING AND PROCEDURE FOR ITS MANUFACTURING AND USING THE BINDING AGENT
DE69230670D1 (en) COMPOSITIONS CONTAINING A BLOOD CLOTH POLYMER MATRIX FOR THE ADMINISTRATION OF OSTEOGENIC PROTEINS
ATE187646T1 (en) USE OF ACTIVE INGREDIENTS CONTAINING COPPER TO ACCELERATE WOUND HEALING
DE3764478D1 (en) SURGICAL WASHER CLOSURE.
IE873075L (en) Wound healing and bone regeneration
DK31088D0 (en) BLOOD COAGULATOR REDUCING PEPTIDE DERIVATIVES
DE68926248D1 (en) p100 "new" human protein and the use of this protein for the detection of preneoplasmic or neoplasmic in humans
ZA896468B (en) Lyophilization of red blood cells
DE69008664D1 (en) IRRADIATION OF BLOOD PRODUCTS.
BG94619A (en) METHOD OF EVAPORATION OF COMPOUNDS USED TO APPLY THEM IN THE FORM OF VAPOR
SE8602405D0 (en) NEW FORMULATION
ES2097120T3 (en) STABILIZATION OF HIGHLY PURIFIED PROTEINS.
ES2039666T3 (en) CONCENTRATE OF PROTEINS COAGULABLE BY THE THROMBINE, ITS PROCEDURE FOR OBTAINING AND ITS THERAPEUTIC USE.
NO873993L (en) PROCEDURE FOR PREPARING FLUORIDE AND CALCIUM PREPARATIONS WITH LONG-RELEASE.
AU4626389A (en) Use of minoxidil for wound healing
RU93058532A (en) PHARMACEUTICAL COMPOSITION FOR OSTEOINDUCTION, METHOD FOR NEW BONE GENERATION
ATE156363T1 (en) WOUND HEALING
FI101797B1 (en) STLV-III virus related polypeptides, diagnostic systems, and assay methods
DE3584926D1 (en) TREATMENT OF OEDEMS WITH HIGH PROTEIN CONTENT BY DIRECT APPLICATION OF BENZOPYRON.
DE69017825D1 (en) Treatment of liver diseases using pyrrole-quinoline-quinone triesters and new pyrrole-quinoline-quinone triesters.
DE3583698D1 (en) PERCUTANIC ABSORPTION ACCELERATOR AND PREPARATION CONTAINING THEM.
ATE96330T1 (en) HEALING WOUNDS.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8204064-3

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8204064-3

Format of ref document f/p: F