SE0302312D0 - Peptide-based passive immunization therapy for treatment of atherosclerosis - Google Patents

Peptide-based passive immunization therapy for treatment of atherosclerosis

Info

Publication number
SE0302312D0
SE0302312D0 SE0302312A SE0302312A SE0302312D0 SE 0302312 D0 SE0302312 D0 SE 0302312D0 SE 0302312 A SE0302312 A SE 0302312A SE 0302312 A SE0302312 A SE 0302312A SE 0302312 D0 SE0302312 D0 SE 0302312D0
Authority
SE
Sweden
Prior art keywords
passive immunization
atherosclerosis
treatment
peptide
immunization therapy
Prior art date
Application number
SE0302312A
Other languages
English (en)
Inventor
Jan Nilsson
Roland Carlsson
Jenny Bengtsson
Leif Strandberg
Original Assignee
Forskarpatent I Syd Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0202959A external-priority patent/SE0202959D0/sv
Application filed by Forskarpatent I Syd Ab filed Critical Forskarpatent I Syd Ab
Priority to SE0302312A priority Critical patent/SE0302312D0/sv
Publication of SE0302312D0 publication Critical patent/SE0302312D0/sv
Priority to AU2003263712A priority patent/AU2003263712A1/en
Priority to PCT/SE2003/001469 priority patent/WO2004030698A1/en
Priority to TW097111600A priority patent/TW200835517A/zh
Priority to TW092126462A priority patent/TWI299666B/zh
Priority to US10/679,032 priority patent/US7468183B2/en
Priority to CN2011102300859A priority patent/CN102380097A/zh
Priority to AU2003267905A priority patent/AU2003267905B2/en
Priority to BR0315042-9A priority patent/BR0315042A/pt
Priority to RU2005113235/15A priority patent/RU2322260C2/ru
Priority to CN200380104103.2A priority patent/CN1717251B/zh
Priority to PT03748843T priority patent/PT1545609E/pt
Priority to DE60336068T priority patent/DE60336068D1/de
Priority to EP10075393A priority patent/EP2359848A1/en
Priority to CN2010101282350A priority patent/CN102172400A/zh
Priority to CN2010101282346A priority patent/CN102319429A/zh
Priority to EEP200500012A priority patent/EE200500012A/xx
Priority to ES03748843T priority patent/ES2387423T3/es
Priority to PCT/SE2003/001547 priority patent/WO2004030607A2/en
Priority to JP2005500961A priority patent/JP2006506450A/ja
Priority to AT03748843T priority patent/ATE498407T1/de
Priority to EP10075394A priority patent/EP2361633A1/en
Priority to DK03748843.4T priority patent/DK1545609T3/da
Priority to CA002500895A priority patent/CA2500895A1/en
Priority to PL376964A priority patent/PL376964A1/pl
Priority to EP03748843A priority patent/EP1545609B1/en
Priority to SI200331982T priority patent/SI1545609T1/sl
Priority to US11/323,123 priority patent/US7601353B2/en
Priority to HK06107155.0A priority patent/HK1087018A1/xx
Priority to US11/612,591 priority patent/US20080008702A1/en
Priority to US11/928,221 priority patent/US7521046B2/en
Priority to RU2007140978/15A priority patent/RU2007140978A/ru
Priority to US12/258,745 priority patent/US8114966B2/en
Priority to AU2009201260A priority patent/AU2009201260B2/en
Priority to JP2010001795A priority patent/JP2010104374A/ja
Priority to JP2010001796A priority patent/JP2010104375A/ja
Priority to JP2010001794A priority patent/JP2010136721A/ja
Priority to JP2010141960A priority patent/JP2010222378A/ja
Priority to CY20111100305T priority patent/CY1112229T1/el
Priority to US13/272,297 priority patent/US20120070426A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE0302312A 2002-10-04 2003-08-27 Peptide-based passive immunization therapy for treatment of atherosclerosis SE0302312D0 (sv)

Priority Applications (40)

Application Number Priority Date Filing Date Title
SE0302312A SE0302312D0 (sv) 2002-10-04 2003-08-27 Peptide-based passive immunization therapy for treatment of atherosclerosis
AU2003263712A AU2003263712A1 (en) 2002-10-04 2003-09-22 Peptide-based passive immunization therapy for treatment of atherosclerosis
PCT/SE2003/001469 WO2004030698A1 (en) 2002-10-04 2003-09-22 Peptide-based passive immunization therapy for treatment of atherosclerosis
TW097111600A TW200835517A (en) 2002-10-04 2003-09-25 Peptide-based passive immunization therapy for treatment of atherosclerosis
TW092126462A TWI299666B (en) 2002-10-04 2003-09-25 Peptide-based passive immunization therapy for treatment of atherosclerosis
US10/679,032 US7468183B2 (en) 2002-10-04 2003-10-03 Antibody immunization therapy for treatment of atherosclerosis
EP03748843A EP1545609B1 (en) 2002-10-04 2003-10-06 Antibodies directed against oxidised apolipoprotein B
SI200331982T SI1545609T1 (sl) 2002-10-04 2003-10-06 Protitelesa, usmerjena proti oksidiranemu apolipoproteinu B
ES03748843T ES2387423T3 (es) 2002-10-04 2003-10-06 Anticuerpos dirigidos contra apoliproteína b oxidada
CA002500895A CA2500895A1 (en) 2002-10-04 2003-10-06 Peptide-based passive immunization therapy for treatment of atherosclerosis
BR0315042-9A BR0315042A (pt) 2002-10-04 2003-10-06 Terapia para o tratamento de aterosclerose baseada em imunização passiva por peptìdeo
RU2005113235/15A RU2322260C2 (ru) 2002-10-04 2003-10-06 Пассивная иммунизационная терапия на основе пептидов для лечения атеросклероза
CN200380104103.2A CN1717251B (zh) 2002-10-04 2003-10-06 用于治疗动脉粥样硬化的肽基被动免疫接种疗法
PT03748843T PT1545609E (pt) 2002-10-04 2003-10-06 Anticorpos dirigidos contra apolipoprote?na b oxidada
DE60336068T DE60336068D1 (de) 2002-10-04 2003-10-06 Antikörper gerichtet gegen oxidierten Apolipoprotein B
EP10075393A EP2359848A1 (en) 2002-10-04 2003-10-06 Peptide-based passive immunization therapy for treatment of atherosclerosis
CN2010101282350A CN102172400A (zh) 2002-10-04 2003-10-06 用于治疗动脉粥样硬化的肽基被动免疫接种疗法
CN2010101282346A CN102319429A (zh) 2002-10-04 2003-10-06 用于治疗动脉粥样硬化的肽基被动免疫接种疗法
EEP200500012A EE200500012A (et) 2002-10-04 2003-10-06 Peptiid-pähine passiivne immunoteraapia ateroskleroosi raviks
CN2011102300859A CN102380097A (zh) 2002-10-04 2003-10-06 用于治疗动脉粥样硬化的肽基被动免疫接种疗法
PCT/SE2003/001547 WO2004030607A2 (en) 2002-10-04 2003-10-06 Peptide-based passive immunization therapy for treatment of atherosclerosis
JP2005500961A JP2006506450A (ja) 2002-10-04 2003-10-06 粥状動脈硬化の治療用のペプチドベースの受動免疫療法
AT03748843T ATE498407T1 (de) 2002-10-04 2003-10-06 Antikörper gerichtet gegen oxidierten apolipoprotein b
EP10075394A EP2361633A1 (en) 2002-10-04 2003-10-06 Peptide-based passive immunization therapy for treatment of atherosclerosis
DK03748843.4T DK1545609T3 (da) 2002-10-04 2003-10-06 Antistoffer rettet mod oxideret apolipoprotein B
AU2003267905A AU2003267905B2 (en) 2002-10-04 2003-10-06 Peptide-based passive immunization therapy for treatment of atherosclerosis
PL376964A PL376964A1 (pl) 2002-10-04 2003-10-06 Leczenie miażdżycy tętnic przez bierne uodpornienie peptydem
US11/323,123 US7601353B2 (en) 2002-10-04 2005-12-30 Peptide-based passive immunization therapy for treatment of atherosclerosis
HK06107155.0A HK1087018A1 (en) 2002-10-04 2006-06-23 Peptide-based passive immunization therapy for treatment of atherosclerosis
US11/612,591 US20080008702A1 (en) 2002-10-04 2006-12-19 Antibody immunization therapy for treatment of atherosclerosis
US11/928,221 US7521046B2 (en) 2002-10-04 2007-10-30 Antibody immunization therapy for treatment of atherosclerosis
RU2007140978/15A RU2007140978A (ru) 2002-10-04 2007-11-02 Пассивная иммунизационная терапия на основе пептидов для лечения атеросклероза
US12/258,745 US8114966B2 (en) 2002-10-04 2008-10-27 Peptide-based passive immunization therapy for treatment of atherosclerosis
AU2009201260A AU2009201260B2 (en) 2002-10-04 2009-03-31 Peptide-based passive immunization therapy for treatment of atherosclerosis
JP2010001794A JP2010136721A (ja) 2002-10-04 2010-01-07 粥状動脈硬化の治療用のペプチドベースの受動免疫療法
JP2010001795A JP2010104374A (ja) 2002-10-04 2010-01-07 粥状動脈硬化の治療用のペプチドベースの受動免疫療法
JP2010001796A JP2010104375A (ja) 2002-10-04 2010-01-07 粥状動脈硬化の治療用のペプチドベースの受動免疫療法
JP2010141960A JP2010222378A (ja) 2002-10-04 2010-06-22 粥状動脈硬化の治療用のペプチドベースの受動免疫療法
CY20111100305T CY1112229T1 (el) 2002-10-04 2011-03-21 Αντισωματα κατευθυνομενα εναντι οξειδωμενης απολιποπρωτεϊνης β
US13/272,297 US20120070426A1 (en) 2002-10-04 2011-10-13 Peptide-based passive immunization therapy for the treatment of atherosclerosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0202959A SE0202959D0 (sv) 2002-10-04 2002-10-04 Peptide-Base passive immunization therapy for treatment of atherosclerosis
SE0302312A SE0302312D0 (sv) 2002-10-04 2003-08-27 Peptide-based passive immunization therapy for treatment of atherosclerosis

Publications (1)

Publication Number Publication Date
SE0302312D0 true SE0302312D0 (sv) 2003-08-27

Family

ID=28677712

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0302312A SE0302312D0 (sv) 2002-10-04 2003-08-27 Peptide-based passive immunization therapy for treatment of atherosclerosis

Country Status (20)

Country Link
US (6) US7468183B2 (sv)
EP (3) EP1545609B1 (sv)
JP (5) JP2006506450A (sv)
CN (3) CN102172400A (sv)
AT (1) ATE498407T1 (sv)
AU (2) AU2003263712A1 (sv)
BR (1) BR0315042A (sv)
CY (1) CY1112229T1 (sv)
DE (1) DE60336068D1 (sv)
DK (1) DK1545609T3 (sv)
EE (1) EE200500012A (sv)
ES (1) ES2387423T3 (sv)
HK (1) HK1087018A1 (sv)
PL (1) PL376964A1 (sv)
PT (1) PT1545609E (sv)
RU (2) RU2322260C2 (sv)
SE (1) SE0302312D0 (sv)
SI (1) SI1545609T1 (sv)
TW (2) TWI299666B (sv)
WO (1) WO2004030698A1 (sv)

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EP1531162A1 (en) * 2003-11-14 2005-05-18 Heinz Vollmers Adenocarcinoma specific antibody SAM-6, and uses thereof
DE10353175A1 (de) 2003-11-14 2005-06-16 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper mit fettsenkender Wirkung
GB0517878D0 (en) * 2005-09-02 2005-10-12 Bioinvent Int Ab Immunotherapeutic treatment
NZ586303A (en) * 2007-12-28 2012-03-30 Bioinvent Int Ab Antibody-containing formulation for the use for treating cardiovascular diseases associated with atherosclerosis
MX2011004001A (es) 2008-10-14 2011-05-19 Genentech Inc Variantes de inmunoglobulinas y sus usos.
EP2393836A4 (en) * 2009-02-09 2012-09-26 Patrys Ltd SAM-6 VARIANTS, TARGET AND USE PROCESS
EP2408812B1 (en) 2009-03-17 2015-12-16 CardioVax, LLC Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis and related proteins, peptides and compositions
CU23736A1 (es) 2009-05-04 2011-11-15 Centro Inmunologia Molecular Anticuerpos que reconocen sulfatidos y proteoglicanos sulfatados y su uso
CA2772380A1 (en) * 2009-08-28 2011-03-03 Genentech, Inc. Methods of treatment using anti-oxidized ldl antibodies
EP2499488A1 (en) 2009-11-14 2012-09-19 Kuang-Yuh Chyu Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis
CN103501806A (zh) 2010-11-12 2014-01-08 赛达斯西奈医疗中心 用于治疗和/或预防动脉瘤的免疫调节方法和系统
EP2637689A2 (en) 2010-11-12 2013-09-18 Cedars-Sinai Medical Center Immunomodulatory methods and systems for treatment and/or prevention of hypertension
PT2864350T (pt) * 2012-06-21 2018-05-14 Hoffmann La Roche Análogos do glucagon que apresentam uma atividade sobre o recetor do gip
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
WO2017210360A1 (en) 2016-05-31 2017-12-07 Cardiovax, Llc Methods for diagnosing and treating systemic lupus erythematosus
CN110950952A (zh) * 2019-12-17 2020-04-03 东莞市东阳光生物药研发有限公司 制备抗体的方法

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US4970144A (en) * 1984-12-31 1990-11-13 International Genetic Engineering Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5972890A (en) * 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5196324A (en) * 1989-12-15 1993-03-23 Eli Lilly And Company Monoclonal antibodies reactive with a human atheroma associated antigen
WO1994000592A1 (en) * 1992-06-26 1994-01-06 Exocell, Inc. Monoclonal antibodies against glycated low density lipoprotein
US5678548A (en) 1995-07-20 1997-10-21 The United States Of America As Represented By The Department Of Health And Human Services System and method for performing in vivo imaging and oxymetry and FT microscopy by pulsed radiofrequency electron paramagnetic resonance
CN1206421A (zh) * 1995-11-01 1999-01-27 科斯药品公司 载脂蛋白e2和阿尔采默氏病的治疗
KR0185334B1 (ko) * 1995-11-02 1999-04-01 김은영 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이
GB9620153D0 (en) 1996-09-27 1996-11-13 Univ Strathclyde Non-naturally occurring lipoprotein particle
GB9701425D0 (en) 1997-01-24 1997-03-12 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
GB9705831D0 (en) * 1997-03-20 1997-05-07 Univ Leicester Oxidised ldl
US6635623B1 (en) 1997-06-13 2003-10-21 Baylor College Of Medicine Lipoproteins as nucleic acid vectors
US6225070B1 (en) 1997-08-07 2001-05-01 The Regents Of The University Of California Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma
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US6156315A (en) 1997-10-10 2000-12-05 The Trustees Of Columbia University In The City Of New York Method for inhibiting the binding of low density lipoprotein to blood vessel matrix
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CZ20022971A3 (cs) * 2000-03-03 2003-02-12 Smithkline Beecham Biologicals S. A. Vakcinační prostředek vhodný pro léčbu aterosklerózy
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
US20030105003A1 (en) * 2001-04-05 2003-06-05 Jan Nilsson Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
JP4159300B2 (ja) 2001-07-05 2008-10-01 株式会社リコー 画像定着装置及び画像形成装置

Also Published As

Publication number Publication date
US7521046B2 (en) 2009-04-21
TW200835517A (en) 2008-09-01
JP2006506450A (ja) 2006-02-23
DE60336068D1 (de) 2011-03-31
ATE498407T1 (de) 2011-03-15
US20040202653A1 (en) 2004-10-14
RU2322260C2 (ru) 2008-04-20
EP1545609A2 (en) 2005-06-29
JP2010222378A (ja) 2010-10-07
PL376964A1 (pl) 2006-01-09
US20090155258A1 (en) 2009-06-18
CN102319429A (zh) 2012-01-18
EP2359848A1 (en) 2011-08-24
JP2010104374A (ja) 2010-05-13
AU2009201260B2 (en) 2011-07-28
EP1545609B1 (en) 2011-02-16
SI1545609T1 (sl) 2011-05-31
AU2003263712A1 (en) 2004-04-23
US8114966B2 (en) 2012-02-14
US20070098723A1 (en) 2007-05-03
US7468183B2 (en) 2008-12-23
JP2010104375A (ja) 2010-05-13
HK1087018A1 (en) 2006-10-06
CY1112229T1 (el) 2015-12-09
BR0315042A (pt) 2005-08-23
CN102380097A (zh) 2012-03-21
AU2009201260A1 (en) 2009-04-23
TW200418504A (en) 2004-10-01
DK1545609T3 (da) 2011-05-02
WO2004030698A1 (en) 2004-04-15
ES2387423T3 (es) 2012-09-21
JP2010136721A (ja) 2010-06-24
US20080075716A1 (en) 2008-03-27
CN102172400A (zh) 2011-09-07
EE200500012A (et) 2005-08-15
US20080008702A1 (en) 2008-01-10
US20120070426A1 (en) 2012-03-22
US7601353B2 (en) 2009-10-13
EP2361633A1 (en) 2011-08-31
PT1545609E (pt) 2011-05-11
RU2007140978A (ru) 2009-05-10
RU2005113235A (ru) 2006-01-20
TWI299666B (en) 2008-08-11

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