RU2034456C1 - Method of regulation of camel female dairy productivity - Google Patents

Abstract

FIELD: animal husbandry. SUBSTANCE: prolonged form of cattle biosynthetic somatotropin is injected to camel female by subcutaneous route. Dose is 500-1200 mg per a head. Preparation is administrated 1-2 months after calving for lactation period with interval 14-35 days. EFFECT: increased dairy productivity of camel female. 1 tbl

Description

 The invention relates to animal husbandry, in particular to methods for increasing the milk productivity of camels through the use of growth hormone.

 A known method of increasing the milk productivity of cows based on the use of bovine growth hormone (BST). The method consists in the fact that BST is administered to cows intramuscularly at 2-4-week intervals. At the same time, the milk productivity of cows for lactation increased by an average of 20% and improved feed use by 5-10% (Current status of studies of cattle growth hormone. USA). RZh VNIITEI Agroprom "Animal husbandry (biological basis)." N 3, 1989, p. 7; Bath D.L. Current status of bovine somatotropin research and education programs. Geurnsey Breeders' J. 1988. 156, 4: 21-22.

 A known method of using somatotropin in cattle, consisting in the fact that lactating cows of the Holstein breed 63-146 days after calving daily for 14 days were subcutaneously administered 51.5 IU / day ST. The introduction of CT increased milk yield by 31% and animal feed consumption did not increase (Effect of somatotropin in cattle on the level of irreversible losses and kinetics of glucose and unesterified fatty acids in dairy cows. USA). RZh VNIITEI Agroprom "Animal husbandry (biological basis)", N 9, 1989, p.7; Bauman D.E. Peel C.I. Steinhour W. D. (e. A.). Effect of bovine somatorofin on metabolism of lactating dairy cows: influence on rates of irreversible loss and oxidation of glucose and nonesterified fatty acids. J. Nutrit. 1988. 118, 8: 1031-1040).

 A known method of increasing the milk productivity of cows by subcutaneous administration of bovine growth hormone (activity 1.4 u / mg of the drug) for 7 days in the final stage of lactation. The milk productivity of cows increased by 49.6%. The rate of blood flow through the vessels of the breast increased by 47.8%. However, 21 days after the end of the treatment, both indicators returned to the initial level (Effect of growth hormone on milk productivity, milk composition, plasma biochemical parameters blood and glucose and acetate consumption by the mammary gland of cows of the Jersey breed. Great Britain). RZh VNIITEI Agroprom "Animal husbandry (biological basis)", N 6, 1990, p. 18. Fullerton F.M. Fleet I.R. Heap R.B. (e.a.). Cardiovascular responses and mammary substrate uptace in Jersey cows treated with pituitary derived growth hormone during late lactation. J. Dairy Res. 1989. 56, 1: 27-35.

 When using high doses of growth hormone (31-50 mg / day) in long-term experiments, the milk productivity of cows increased immediately by 5.6 kg (4.1-11.5 kg) with daily injections; 4.4 kg (1.8-8.3 kg) when injected every 14 days in appropriate doses and 4.2 kg (0.4-6.3 kg) with the introduction of the hormone every 28 days. In the case of injections at intervals of 14 or 28 days, significant fluctuations in the milk and fat and protein levels were observed (Analysis of the results of the use of growth hormone in cattle breeding in 1988, France). RZh VNIITEI Agroprom "Dairy and beef cattle breeding", N 1, 1990, p.25; Chilliard Y. Les nombreux resultats 1988 sur la somatotropine. Product lait. mod. 1988, 176: 92-93.

 Known methods of using exogenous somatotropin (BST) daily, once a week, once every 2 weeks, respectively, for 20 weeks from 3-4 months. lactation. Regardless of the type of the nervous system, the peak of milk yield was noted at 5-6 weeks from the start of the administration of BLT, and at 17-18 weeks a decrease in productivity was noted. BST had almost no effect on the production of highly stress-resistant cows and significantly increased the yield of low-resistance animals (Gushchik TS The influence of the administration of exogenous somatotropic hormone on the milk production of cows. In the book Physiological and biochemical fundamentals of the realization of the genetic potential of milk production. 1988, pp. 34-37 )

 A known method of using recombinant (biosynthetic) STH in large quantities. The introduction of STH increased the yield of cows by 10-15% in short-term experiments (4-10 days) and by 30-50% in longer-term experiments (70 and 84 days) in comparison with the control. The most effective was the introduction of the drug to highly productive Holstein cows at a high level of nutrition. The animals consumed more feed, which was more efficiently used for milk (The potential role of bovine GH in increasing the milk production of cows. Ireland). RZh VNIITEI Agroprom "Dairy and beef cattle breeding", N 3, 1990, p.25; Anon. The potencial role of bovine somatotropin (BST) to increase the efficiency of milk production. Irish veter. News. 1988.1a, 6: 13-16.

 With subcutaneous administration to the cows of the Holstein breed of recombinant bovine somatotropin in the period from 98 to 112 days after calving at a dose of 350 mg / goal. every 14 days to 305 days of lactation, milk yield was significantly increased, however, the fat and protein content in milk, food intake and energy balance remained unchanged (F. Guillermo. Effects of Recombinant Bovine Somatotropin on Nutritionale Status and Liver Function of Lactating Dairy Cows. J Dairy Sci, 1990, 73: 3276-3286).

 There is a method of increasing the milk productivity of a ruminant by injecting growth hormone between the onset of puberty and before the first birth. In this case, the milk productivity of animals was increased based on the intensification of the development of the mammary parenchyma (US patent N 4521409, class A 61 K 37/00, 1985).

 The closest in technical essence and the achieved result is a method of using somatotropin to increase milk production of animals, taken as a prototype, including subcutaneous administration of recombinant somatotropin to cattle in newborn cows at a dose of 320, 640 and 960 mg per head every 28 days. within 252 days The cows were kept in standard rooms and fed them an individually complete mixture consisting of 50% concentrates and 50% coarse fodder. They fed the cows ad libitum. An optimal response was obtained with a dose of the hormone 640 mg. With a low, medium and high dose of the hormone, milk yield was 21.8, respectively; 24.2 and 23.8 kg / day. at 20.9 kg / day in the control, fat production of 1134, 1273 and 1247 g / d. at 1050 in the control, and the production of milk protein: 786, 872 and 849 g / day. compared to 742 g / day. in control. When treated with growth hormone, the live weight of cows decreased from 587 kg in the control to 576, 574 and 573 kg in the experimental groups (Effect of long-term administration of recombinant bovine growth hormone on milk production, live weight and feed intake in dairy cows. Netherlands). RZh VNIITEI Agroprom "Dairy and beef cattle breeding". N 3, 1990, p. 26; Oldenbroek I.K. Garssen G.I. Forbes A.B. Jonker L.T. The effect of treatment of dairy cows of different breeds with recombinantly derived bovine somatotropin in a sustained delivery vehicle. Livestock Product. Sc. 1989.21, 1: 13-34.

 Known methods were used to increase the milk production of cows. However, somatotropin in cattle has species specificity and the method and effect of its use for the milk production of camels is not known.

 The purpose of the invention is the increase in milk production of camels.

 This goal is achieved by the fact that in the known method, which includes subcutaneous administration of a biologically active preparation to an animal, a feature is that the biosynthetic somatotropin of cattle is administered subcutaneously to camels in a dose of 500-1200 mg per head, starting from 1-2 months. after calving during lactation with an interval of 14-35 days.

 A dose of bSTG below 600-640 mg per head in the known methods did not significantly affect the increase in milk productivity of cows; at a dose of bSTH over 1200 mg per head, a significant violation of the hormonal status of the animal’s body occurs. In addition, with a dose of bSTH over 1200 mg per head, an increase in milk per 1 mg of bSTG is more expensive than with a dose of 600-1200 mg per head.

PRI me R. At the camel farm of the farm Koktalsky, Panfilovsky district, Taldy-Kurgan region in 1991-1992, 18 camel-analogues of the bacterian breed for 1-2 months. lactation subcutaneously behind the scapula was administered a prolonged preparation of bovine somatotropin (bSTH) with an interval of 14-35 days. during lactation. Moreover, in one group of animals (9 animals), bSTH was administered at a dose of 500 mg per head, and in the second group (9 animals) 1200 mg per head. During the experiment, the milk productivity of the camels increased in the first group by 0.2-0.95 kg per day, in the second by 0.9-1.8 kg / day. (tab.)
The best results were obtained by injecting a dose of 1200 mg of the drug per head.

The application of the proposed method allows to increase the milk productivity of camels by 24-62%. At the same time, an increase in the fat content in milk of camels to 40% is noted. A known method provides an increase in milk productivity of cows by 10-35%
The method is applicable in camel farms of the Russian Federation, for example, in the Astrakhan region, Turkmenistan, Kazakhstan, Uzbekistan, Kyrgyzstan, Tajikistan, as well as Iran, Iraq, Pakistan and other Arab countries engaged in camel breeding.

Claims (1)

 METHOD FOR REGULATING THE Dairy Productivity of Camels, including subcutaneous administration of a biologically active preparation into their bodies, characterized in that the camels are injected subcutaneously with biosynthetic somatotropin of cattle of prolonged form in a dose of 500 to 1200 mg / goal from 1 2 months after calving for 1 2 months after calving lactation with an interval of 14 to 35 days.

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