RS51136B - Supstituisani pirolopiridini, kompozicije koje ih sadrže, postupak za njihovo dobijanje i upotreba - Google Patents

Supstituisani pirolopiridini, kompozicije koje ih sadrže, postupak za njihovo dobijanje i upotreba

Info

Publication number
RS51136B
RS51136B RSP-2009/0400A RSP20090400A RS51136B RS 51136 B RS51136 B RS 51136B RS P20090400 A RSP20090400 A RS P20090400A RS 51136 B RS51136 B RS 51136B
Authority
RS
Serbia
Prior art keywords
pyridines
producing
composition containing
substituted pyrrolo
substituted
Prior art date
Application number
RSP-2009/0400A
Other languages
English (en)
Inventor
Baptiste Ronan
Catherine Souaille
Fabrice Viviani
Eric Bacque
Pascal Desmazeau
Frank Halley
Michel Tabart
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of RS51136B publication Critical patent/RS51136B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Proizvodi formule (I):gde:1) A i Ar su supstituisane fenil grupe; 2)L je NH-CO-NH;3) W je C(R6), jedan od Y i Z je odabran od N i NO, a drugi je C(R5);4) R1, R5, i R6 su H;5) Ra je H.Prijava sadrži još 17 patentnih zahteva.
RSP-2009/0400A 2005-04-26 2006-04-26 Supstituisani pirolopiridini, kompozicije koje ih sadrže, postupak za njihovo dobijanje i upotreba RS51136B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0504173A FR2884821B1 (fr) 2005-04-26 2005-04-26 Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
PCT/FR2006/000925 WO2006114520A2 (fr) 2005-04-26 2006-04-26 Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
RS51136B true RS51136B (sr) 2010-10-31

Family

ID=35517344

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2009/0400A RS51136B (sr) 2005-04-26 2006-04-26 Supstituisani pirolopiridini, kompozicije koje ih sadrže, postupak za njihovo dobijanje i upotreba

Country Status (33)

Country Link
US (1) US7947706B2 (sr)
EP (1) EP1877409B1 (sr)
JP (1) JP2008539211A (sr)
KR (1) KR20080007229A (sr)
CN (1) CN101166739A (sr)
AR (1) AR061386A1 (sr)
AT (1) ATE433976T1 (sr)
AU (1) AU2006239105A1 (sr)
BR (1) BRPI0613161A2 (sr)
CA (1) CA2605744A1 (sr)
CR (1) CR9463A (sr)
CY (1) CY1109369T1 (sr)
DE (1) DE602006007337D1 (sr)
DK (1) DK1877409T3 (sr)
DO (1) DOP2006000096A (sr)
EA (1) EA012983B1 (sr)
ES (1) ES2328629T3 (sr)
FR (1) FR2884821B1 (sr)
GT (1) GT200600174A (sr)
HR (1) HRP20090494T1 (sr)
IL (1) IL186523A0 (sr)
MA (1) MA29480B1 (sr)
MX (1) MX2007013084A (sr)
NO (1) NO20075918L (sr)
PA (1) PA8671301A1 (sr)
PE (1) PE20071420A1 (sr)
PL (1) PL1877409T3 (sr)
PT (1) PT1877409E (sr)
RS (1) RS51136B (sr)
SI (1) SI1877409T1 (sr)
TN (1) TNSN07360A1 (sr)
TW (1) TW200718701A (sr)
WO (1) WO2006114520A2 (sr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
EP2223925A1 (en) * 2006-10-09 2010-09-01 Takeda Pharmaceutical Company Limited Kinase inhibitors
JP2010505962A (ja) * 2006-10-09 2010-02-25 武田薬品工業株式会社 キナーゼ阻害剤
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
JP5442448B2 (ja) * 2006-12-22 2014-03-12 アステックス、セラピューティックス、リミテッド Ｆｇｆｒインヒビターとしての二環式ヘテロ環式化合物
PL2121687T3 (pl) 2006-12-22 2016-03-31 Astex Therapeutics Ltd Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowej
NZ582772A (en) 2007-07-17 2012-06-29 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
GB0720038D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New compounds
GB0720041D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New Compounds
GB0810902D0 (en) * 2008-06-13 2008-07-23 Astex Therapeutics Ltd New compounds
DE102008052943A1 (de) 2008-10-23 2010-04-29 Merck Patent Gmbh Azaindolderivate
EA022924B1 (ru) 2009-04-03 2016-03-31 Ф.Хоффманн-Ля Рош Аг ТВЁРДАЯ ФОРМА {3-[5-(4-ХЛОРФЕНИЛ)-1Н-ПИРРОЛО[2,3-b]ПИРИДИН-3-КАРБОНИЛ]-2,4-ДИФТОРФЕНИЛ}АМИДА ПРОПАН-1-СУЛЬФОНОВОЙ КИСЛОТЫ И ЕЁ ПРИМЕНЕНИЕ
GB0906470D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
GB0906472D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
US20110030037A1 (en) * 2009-07-07 2011-02-03 Vadim Olshansky Zone migration in network access
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
CA2780190C (en) 2009-11-06 2020-05-05 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
BR112013020041B1 (pt) 2011-02-07 2021-11-23 Plexxikon, Inc Compostos e composições para a modulação de quinases e uso dos mesmos
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
EP2855477A4 (en) * 2012-05-29 2015-11-18 Merck Sharp & Dohme BARYARY COMPOUNDS, ISOTOPICALLY MARKED
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
US20140275082A1 (en) * 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
GB201310464D0 (en) * 2013-06-12 2013-07-24 Lytix Biopharma As Compounds
GB201310460D0 (en) * 2013-06-12 2013-07-24 Lytix Biopharma As Compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3254843B2 (ja) * 1993-08-09 2002-02-12 三菱ウェルファーマ株式会社 新規縮合ヘテロ環誘導体
US6335342B1 (en) * 2000-06-19 2002-01-01 Pharmacia & Upjohn S.P.A. Azaindole derivatives, process for their preparation, and their use as antitumor agents
GB0115109D0 (en) * 2001-06-21 2001-08-15 Aventis Pharma Ltd Chemical compounds
JP2005508904A (ja) * 2001-09-11 2005-04-07 スミスクライン ビーチャム コーポレーション 血管新生阻害剤としてのフロ−及びチエノピリミジン誘導体
WO2003028724A1 (en) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
JP4623962B2 (ja) * 2001-10-22 2011-02-02 ザ・リサーチ・ファウンデーション・オブ・ステイト・ユニバーシティ・オブ・ニューヨーク タンパク質キナーゼおよびホスファターゼ阻害剤、それらを設計する方法、ならびにそれらを使用する方法
EP1490364B1 (en) * 2002-03-28 2007-09-26 Eisai R&D Management Co., Ltd. 7-azaindoles as inhibitors of c-jun n-terminal kinases for the treatment of neurodegenerative disorders
FR2878849B1 (fr) * 2004-12-06 2008-09-12 Aventis Pharma Sa Indoles substitues, compositions les contenant, procede de fabrication et utilisation

Also Published As

Publication number Publication date
DK1877409T3 (da) 2009-10-05
CA2605744A1 (fr) 2006-11-02
WO2006114520A3 (fr) 2007-03-01
EA012983B1 (ru) 2010-02-26
EP1877409B1 (fr) 2009-06-17
TW200718701A (en) 2007-05-16
MX2007013084A (es) 2008-01-11
CN101166739A (zh) 2008-04-23
GT200600174A (es) 2006-12-26
EP1877409A2 (fr) 2008-01-16
DOP2006000096A (es) 2007-04-15
SI1877409T1 (sl) 2009-12-31
MA29480B1 (fr) 2008-05-02
JP2008539211A (ja) 2008-11-13
HRP20090494T1 (hr) 2009-10-31
AR061386A1 (es) 2008-08-27
US7947706B2 (en) 2011-05-24
PE20071420A1 (es) 2007-01-20
ATE433976T1 (de) 2009-07-15
EA200702329A1 (ru) 2008-02-28
PA8671301A1 (es) 2006-12-07
FR2884821A1 (fr) 2006-10-27
DE602006007337D1 (de) 2009-07-30
US20080139606A1 (en) 2008-06-12
NO20075918L (no) 2007-11-19
BRPI0613161A2 (pt) 2010-12-21
PL1877409T3 (pl) 2009-12-31
FR2884821B1 (fr) 2007-07-06
ES2328629T3 (es) 2009-11-16
WO2006114520A2 (fr) 2006-11-02
PT1877409E (pt) 2009-09-16
KR20080007229A (ko) 2008-01-17
TNSN07360A1 (en) 2008-12-31
CR9463A (es) 2008-02-21
IL186523A0 (en) 2008-01-20
AU2006239105A1 (en) 2006-11-02
CY1109369T1 (el) 2014-07-02

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