PT946548E - Novos derivados de pirrolidino amida substituidos por heterociclos - Google Patents

Novos derivados de pirrolidino amida substituidos por heterociclos

Info

Publication number
PT946548E
PT946548E PT97946443T PT97946443T PT946548E PT 946548 E PT946548 E PT 946548E PT 97946443 T PT97946443 T PT 97946443T PT 97946443 T PT97946443 T PT 97946443T PT 946548 E PT946548 E PT 946548E
Authority
PT
Portugal
Prior art keywords
heterocycles
amide derivatives
derivatives substituted
pyrrolidine amide
new pyrrolidine
Prior art date
Application number
PT97946443T
Other languages
English (en)
Inventor
George D Maynard
Elisabeth M Kudlacz
Thimothy P Burkholder
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of PT946548E publication Critical patent/PT946548E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PT97946443T 1996-12-19 1997-11-03 Novos derivados de pirrolidino amida substituidos por heterociclos PT946548E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76981296A 1996-12-19 1996-12-19

Publications (1)

Publication Number Publication Date
PT946548E true PT946548E (pt) 2002-06-28

Family

ID=25086573

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97946443T PT946548E (pt) 1996-12-19 1997-11-03 Novos derivados de pirrolidino amida substituidos por heterociclos

Country Status (21)

Country Link
EP (1) EP0946548B1 (pt)
JP (1) JP4195512B2 (pt)
KR (1) KR100514263B1 (pt)
CN (1) CN1119344C (pt)
AR (1) AR009665A1 (pt)
AT (1) ATE214063T1 (pt)
AU (1) AU723966B2 (pt)
BR (1) BR9714057A (pt)
CA (1) CA2275527C (pt)
DE (1) DE69710921T2 (pt)
DK (1) DK0946548T3 (pt)
ES (1) ES2169881T3 (pt)
HK (1) HK1020947A1 (pt)
HU (1) HUP0000315A3 (pt)
IL (1) IL130223A (pt)
NO (1) NO317760B1 (pt)
NZ (1) NZ335975A (pt)
PT (1) PT946548E (pt)
TW (1) TW486477B (pt)
WO (1) WO1998027086A1 (pt)
ZA (1) ZA9711271B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID29137A (id) * 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
SK252004A3 (sk) * 2001-07-20 2005-03-04 Pfizer Products Inc. Použitie antagonistov receptora NK-1 na výrobu liečiva na liečenie abnormálneho úzkostného správania domácich zvierat a spôsob screeningu skúšanej zlúčeniny s cieľom stanoviť anxiolytickú účinnosť u psov
BRPI0815674A2 (pt) * 2007-08-22 2015-02-18 Hoffmann La Roche Aril-éter de pirrolidina como antagonista de receptor de nk3
HUE064995T2 (hu) 2018-10-29 2024-04-28 Boehringer Ingelheim Int Piridinil-szulfonamid-származékok, gyógyszerkészítmények és azok felhasználása

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
CA2160462C (en) * 1993-05-06 1998-12-15 Timothy P. Burkholder Substituted pyrrolidin-3-yl-alkyl-piperidines useful as tachykinin antagonists
JPH11513991A (ja) * 1995-11-17 1999-11-30 ヘキスト・マリオン・ルセル・インコーポレイテツド アレルギー性疾患の治療に有用な置換4−(1h−ベンズイミダゾル−2−イル−アミノ)ピペリジン

Also Published As

Publication number Publication date
EP0946548B1 (en) 2002-03-06
KR20000057668A (ko) 2000-09-25
AU723966B2 (en) 2000-09-07
ES2169881T3 (es) 2002-07-16
CA2275527C (en) 2003-09-23
HUP0000315A2 (hu) 2001-04-28
JP2001506650A (ja) 2001-05-22
HUP0000315A3 (en) 2002-01-28
DE69710921D1 (de) 2002-04-11
DE69710921T2 (de) 2002-09-19
DK0946548T3 (da) 2002-06-24
AU5160798A (en) 1998-07-15
KR100514263B1 (ko) 2005-09-15
CN1119344C (zh) 2003-08-27
WO1998027086A1 (en) 1998-06-25
ATE214063T1 (de) 2002-03-15
AR009665A1 (es) 2000-04-26
IL130223A0 (en) 2000-06-01
ZA9711271B (en) 1998-06-19
EP0946548A1 (en) 1999-10-06
NO993013L (no) 1999-08-18
HK1020947A1 (en) 2000-05-26
JP4195512B2 (ja) 2008-12-10
NO317760B1 (no) 2004-12-13
CN1241185A (zh) 2000-01-12
NO993013D0 (no) 1999-06-18
BR9714057A (pt) 2000-05-09
CA2275527A1 (en) 1998-06-25
NZ335975A (en) 2000-11-24
TW486477B (en) 2002-05-11
IL130223A (en) 2005-09-25

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