PT78211B - Process for preparing carbapenem derivatives - Google Patents

Process for preparing carbapenem derivatives

Info

Publication number: PT78211B
Authority: PT; Portugal
Prior art keywords: carbapenem derivatives; preparing carbapenem; preparing; derivatives; carbapenem
Prior art date: 1983-03-08

Application number

PT78211A

Other languages

Portuguese (pt)

Other versions

PT78211A (en

Inventor

Pierre Dextraze

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-08

Filing date

1984-03-07

Publication date

1986-08-12

1984-03-07 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1984-04-01 Publication of PT78211A publication Critical patent/PT78211A/en

1986-08-12 Publication of PT78211B publication Critical patent/PT78211B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)

PT78211A 1983-03-08 1984-03-07 Process for preparing carbapenem derivatives PT78211B (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US47137883A	1983-03-08	1983-03-08
US49969183A	1983-06-07	1983-06-07
US55729583A	1983-12-01	1983-12-01

Publications (2)

Publication Number	Publication Date
PT78211A PT78211A (en)	1984-04-01
PT78211B true PT78211B (en)	1986-08-12

Family

ID=27413179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT78211A PT78211B (en)	1983-03-08	1984-03-07	Process for preparing carbapenem derivatives

Country Status (31)

Country	Link
JP (1)	JPH05255250A (en)
KR (1)	KR900002247B1 (en)
AR (1)	AR241016A1 (en)
AT (1)	AT387968B (en)
AU (2)	AU572124B2 (en)
CA (1)	CA1284324C (en)
CH (1)	CH658248A5 (en)
CY (1)	CY1546A (en)
DD (1)	DD228258A5 (en)
DE (1)	DE3408347A1 (en)
DK (1)	DK140584A (en)
ES (2)	ES8505205A1 (en)
FI (1)	FI840863A (en)
FR (1)	FR2542316B1 (en)
GB (1)	GB2136802B (en)
GR (1)	GR81871B (en)
HK (1)	HK82990A (en)
HU (1)	HU193895B (en)
IE (1)	IE57098B1 (en)
IL (1)	IL71149A (en)
IT (1)	IT1178465B (en)
LU (1)	LU85241A1 (en)
NL (1)	NL8400702A (en)
NO (1)	NO166038C (en)
NZ (1)	NZ207346A (en)
OA (1)	OA07674A (en)
PT (1)	PT78211B (en)
SE (2)	SE8401278L (en)
SG (1)	SG35490G (en)
YU (2)	YU46147B (en)
ZW (1)	ZW3884A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683301A (en) *	1982-04-08	1987-07-28	Bristol-Myers Company	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
CA1285940C (en) *	1984-07-02	1991-07-09	Merck & Co., Inc.	Carbapenems having a 2-quaternary heteroarylalkylthio substituent
IE851586L (en) *	1984-07-02	1986-01-02	Interchem Internat S A	I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
US4665169A (en) *	1985-09-11	1987-05-12	Bristol-Myers Company	Carbapenem antibiotics
US4880922A (en) *	1985-11-22	1989-11-14	Bristol-Myers Company	Carbapenems with quaternized heterothioalkylthio substitution at position 2
NZ219892A (en) *	1986-04-15	1991-02-26	Merck & Co Inc	N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
NZ237191A (en) *	1990-02-23	1992-12-23	Sankyo Co	2-((substituted amide) substituted heterocyclylthio) carbpen-2-em derivatives and pharmaceutical compositions
US5712267A (en) *	1991-06-04	1998-01-27	Sankyo Company,. Limited	Carbapenem derivatives, their preparation and their use as antibiotics
JP4648899B2 (en)	2003-06-12	2011-03-09	ビーティージー・インターナショナル・リミテッド	Cyclic hydroxylamine as a neuroactive compound
FR2921258A1 (en) *	2007-09-24	2009-03-27	Oreal	TINCTORIAL COMPOSITION COMPRISING AT LEAST ONE COLOR DISULFIDE / THIOL PRECURSOR, COLORING PROCESS FROM THE COMPOSITION

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55147284A (en) *	1979-04-17	1980-11-17	Sanraku Inc	Novel beta-lactam derivative and its preparation
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (en) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Process for the preparation of 1-carbapenems, and intermediates for their preparation
EP0060612A1 (en) *	1981-02-04	1982-09-22	Beecham Group Plc	Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
US4552873A (en) *	1981-08-19	1985-11-12	Sankyo Company Limited	Carbapenem compounds, and compositions containing them
EP0074599A1 (en) *	1981-09-09	1983-03-23	Takeda Chemical Industries, Ltd.	5,6-cis-Carbapenem derivatives, their production and use
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics

1984
- 1984-02-29 AR AR295877A patent/AR241016A1/en active
- 1984-02-29 DK DK140584A patent/DK140584A/en not_active Application Discontinuation
- 1984-03-01 NZ NZ207346A patent/NZ207346A/en unknown
- 1984-03-05 NL NL8400702A patent/NL8400702A/en not_active Application Discontinuation
- 1984-03-05 ZW ZW38/84A patent/ZW3884A1/en unknown
- 1984-03-05 FI FI840863A patent/FI840863A/en not_active Application Discontinuation
- 1984-03-05 IL IL71149A patent/IL71149A/en unknown
- 1984-03-06 GR GR73999A patent/GR81871B/el unknown
- 1984-03-06 CA CA000448904A patent/CA1284324C/en not_active Expired - Fee Related
- 1984-03-06 CH CH1103/84A patent/CH658248A5/en not_active IP Right Cessation
- 1984-03-07 HU HU84911A patent/HU193895B/en not_active IP Right Cessation
- 1984-03-07 IE IE549/84A patent/IE57098B1/en not_active IP Right Cessation
- 1984-03-07 LU LU85241A patent/LU85241A1/en unknown
- 1984-03-07 FR FR8403553A patent/FR2542316B1/en not_active Expired
- 1984-03-07 DD DD84260663A patent/DD228258A5/en not_active IP Right Cessation
- 1984-03-07 IT IT19945/84A patent/IT1178465B/en active
- 1984-03-07 ES ES530337A patent/ES8505205A1/en not_active Expired
- 1984-03-07 AU AU25360/84A patent/AU572124B2/en not_active Ceased
- 1984-03-07 NO NO840865A patent/NO166038C/en unknown
- 1984-03-07 PT PT78211A patent/PT78211B/en unknown
- 1984-03-07 OA OA58247A patent/OA07674A/en unknown
- 1984-03-07 GB GB08405984A patent/GB2136802B/en not_active Expired
- 1984-03-07 SE SE8401278A patent/SE8401278L/en not_active Application Discontinuation
- 1984-03-07 DE DE19843408347 patent/DE3408347A1/en not_active Withdrawn
- 1984-03-07 AT AT0076984A patent/AT387968B/en not_active IP Right Cessation
- 1984-03-08 KR KR1019840001243A patent/KR900002247B1/en not_active IP Right Cessation
- 1984-03-08 YU YU42084A patent/YU46147B/en unknown
- 1984-11-02 ES ES537349A patent/ES537349A0/en active Granted
1986
- 1986-03-28 YU YU49486A patent/YU46305B/en unknown
1987
- 1987-07-20 AU AU75924/87A patent/AU605491B2/en not_active Ceased
1989
- 1989-04-03 SE SE8901162A patent/SE8901162D0/en not_active Application Discontinuation
1990
- 1990-05-19 SG SG35490A patent/SG35490G/en unknown
- 1990-10-11 HK HK829/90A patent/HK82990A/en unknown
1991
- 1991-03-22 CY CY1546A patent/CY1546A/en unknown
- 1991-09-27 JP JP3274949A patent/JPH05255250A/en active Pending

Also Published As

Publication number	Publication date
NL8400702A (en)	1984-10-01
CH658248A5 (en)	1986-10-31
NO840865L (en)	1984-09-10
SE8901162L (en)	1989-04-03
IE840549L (en)	1984-09-08
DE3408347A1 (en)	1984-09-13
SG35490G (en)	1990-07-13
GB8405984D0 (en)	1984-04-11
DK140584D0 (en)	1984-02-29
CA1284324C (en)	1991-05-21
ATA76984A (en)	1988-09-15
AU605491B2 (en)	1991-01-17
YU46147B (en)	1993-05-28
OA07674A (en)	1985-05-23
FR2542316B1 (en)	1988-10-07
DK140584A (en)	1984-09-09
SE8401278L (en)	1984-09-09
IT8419945A0 (en)	1984-03-07
NZ207346A (en)	1987-01-23
FI840863A (en)	1984-09-09
KR900002247B1 (en)	1990-04-07
ZW3884A1 (en)	1984-10-10
HU193895B (en)	1987-12-28
IL71149A0 (en)	1984-06-29
PT78211A (en)	1984-04-01
AU572124B2 (en)	1988-05-05
HK82990A (en)	1990-10-19
AR241016A2 (en)	1991-04-30
ES530337A0 (en)	1985-05-16
IT1178465B (en)	1987-09-09
IL71149A (en)	1990-03-19
FI840863A0 (en)	1984-03-05
SE8401278D0 (en)	1984-03-07
YU49486A (en)	1987-12-31
HUT34980A (en)	1985-05-28
GR81871B (en)	1984-12-12
AR241016A1 (en)	1991-04-30
ES8507145A1 (en)	1985-08-16
KR840008157A (en)	1984-12-13
LU85241A1 (en)	1984-11-14
CY1546A (en)	1991-03-22
GB2136802A (en)	1984-09-26
SE8901162D0 (en)	1989-04-03
DD228258A5 (en)	1985-10-09
ES537349A0 (en)	1985-08-16
AU7592487A (en)	1987-10-22
YU42084A (en)	1986-08-31
GB2136802B (en)	1987-05-20
NO166038C (en)	1991-05-22
AU2536084A (en)	1984-09-13
IE57098B1 (en)	1992-04-22
FR2542316A1 (en)	1984-09-14
YU46305B (en)	1993-05-28
JPH05255250A (en)	1993-10-05
NO166038B (en)	1991-02-11
ES8505205A1 (en)	1985-05-16
AT387968B (en)	1989-04-10

Publication	Publication Date	Title
YU202784A (en)	1987-02-28	Process for making sfingozine derivatives
HUT34984A (en)	1985-05-28	Process for peneme derivatives
HUT34004A (en)	1985-01-28	Process for preparing n-aryl-alpha-amino-carboxamide derivatives
HUT35697A (en)	1985-07-29	Process for preparing n-acyl-glucopeptide derivatives
YU43357B (en)	1989-06-30	Process for making ergolinic derivatives
PT78211B (en)	1986-08-12	Process for preparing carbapenem derivatives
HUT36459A (en)	1985-09-30	Process for preparing difluoro-pyridine derivatives
YU43196B (en)	1989-04-30	Process for obtaining carbapenem derivatives
HUT35679A (en)	1985-07-29	Process for preparing pyrazolo-pyridine-cycloalkanone derivatives
HU201761B (en)	1990-12-28	Process for producing carbapenem derivatives
HUT34977A (en)	1985-05-28	Process for preparing naphthyl-imidazo-pyridine derivatives
HUT35251A (en)	1985-06-28	Process for preparing fluorenyl-alkyl-imidazole derivatives
PT79346A (en)	1984-11-01	Process for preparing 2-azacycloalkylthiopenem derivatives
PL248114A1 (en)	1985-04-09	Process for preparing penemic derivatives
PT78476B (en)	1986-08-28	Process for preparing hydatoin derivatives
HUT35244A (en)	1985-06-28	Process for preparing phenyl-ethyl-amine derivatives
HUT34022A (en)	1985-01-28	Process for preparing isoxazolyl-ilidazolidinone derivatives
PT78011A (en)	1984-02-01	Process for preparing halobenzophenone-oxime derivatives
HUT35249A (en)	1985-06-28	Process for preparing 6-oxo-decahydro-quinoline derivatives
PT79293B (en)	1986-09-10	Process for the preparation of fluoralkylated carbapenem derivatives
RO88220B (en)	1985-12-31	Process for preparing some cephalosporine derivatives
YU66484A (en)	1986-12-31	Process for making pyridintrionic derivatives
PT79361A (en)	1984-11-01	Process for preparing 9-carbamoyl-fluorene derivatives
HUT34028A (en)	1985-01-28	Process for preparing penem derivatives
PT79184B (en)	1986-11-24	Process for preparing carbapenem derivatives