PT76013B - Process for preparing interferon formulations - Google Patents
Process for preparing interferon formulationsInfo
- Publication number
- PT76013B PT76013B PT76013A PT7601382A PT76013B PT 76013 B PT76013 B PT 76013B PT 76013 A PT76013 A PT 76013A PT 7601382 A PT7601382 A PT 7601382A PT 76013 B PT76013 B PT 76013B
- Authority
- PT
- Portugal
- Prior art keywords
- interferon formulations
- preparing interferon
- preparing
- formulations
- interferon
- Prior art date
Links
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33405281A | 1981-12-23 | 1981-12-23 | |
ZA828580A ZA828580B (en) | 1981-12-23 | 1982-11-19 | Interferon formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
PT76013A PT76013A (en) | 1983-01-01 |
PT76013B true PT76013B (en) | 1986-03-11 |
Family
ID=26989028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT76013A PT76013B (en) | 1981-12-23 | 1982-12-21 | Process for preparing interferon formulations |
Country Status (18)
Country | Link |
---|---|
US (1) | US4496537A (pt) |
EP (1) | EP0082481B2 (pt) |
AU (1) | AU558966B2 (pt) |
CA (1) | CA1207665A (pt) |
DE (1) | DE3262575D1 (pt) |
DK (1) | DK158873C (pt) |
FI (1) | FI70794C (pt) |
HK (1) | HK94487A (pt) |
HU (1) | HU190649B (pt) |
IE (1) | IE54468B1 (pt) |
IL (1) | IL67517A (pt) |
MY (1) | MY8700705A (pt) |
NO (1) | NO161036C (pt) |
NZ (1) | NZ202856A (pt) |
OA (1) | OA07282A (pt) |
PH (1) | PH19869A (pt) |
PT (1) | PT76013B (pt) |
SG (1) | SG70687G (pt) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4600583A (en) * | 1982-09-07 | 1986-07-15 | Tetra Consultants Inc. | Pharmaceutical compositions |
US4469228A (en) * | 1983-05-31 | 1984-09-04 | Schering Corporation | Interferon kit |
JPH0651641B2 (ja) * | 1983-08-29 | 1994-07-06 | 株式会社ミドリ十字 | ガンマ・インターフェロン組成物 |
JPS6034919A (ja) * | 1983-08-04 | 1985-02-22 | Green Cross Corp:The | ガンマ・インタ−フェロン組成物 |
US4855134A (en) * | 1983-10-14 | 1989-08-08 | Sumitomo Pharmaceuticals Company, Limited | Sustained-release preparation |
JPS60243028A (ja) * | 1984-04-28 | 1985-12-03 | Kyowa Hakko Kogyo Co Ltd | インタ−フエロンの可溶化方法 |
EP0168008A3 (en) * | 1984-07-10 | 1986-12-30 | Takeda Chemical Industries, Ltd. | Stable composition of gamma-interferon |
US5196323A (en) * | 1985-04-27 | 1993-03-23 | Boehringer Ingelheim International Gmbh | Process for preparing and purifying alpha-interferon |
US4847079A (en) * | 1985-07-29 | 1989-07-11 | Schering Corporation | Biologically stable interferon compositions comprising thimerosal |
DE3628468A1 (de) * | 1986-08-21 | 1988-03-03 | Thomae Gmbh Dr K | Neue applikationsformen fuer (alpha)-interferone |
CA1320905C (en) * | 1986-11-06 | 1993-08-03 | Joseph M. Cummins | Treatment of immuno-resistant disease |
US4851220A (en) * | 1986-11-26 | 1989-07-25 | Schering Corporation | Stable oleaginous gel |
US4853218A (en) * | 1987-02-24 | 1989-08-01 | Schering Corporation | Zinc-protamine-alpha interferon complex |
US4895716A (en) * | 1987-06-09 | 1990-01-23 | Biogen, Inc. | Stabilized formulations of gamma interferons |
US4871538A (en) * | 1987-07-13 | 1989-10-03 | Schering Corporation | Insoluble copper-alpha interferon complex |
US5151265A (en) * | 1987-11-03 | 1992-09-29 | Genentech, Inc. | Gamma interferon formulation |
US5004605A (en) * | 1987-12-10 | 1991-04-02 | Cetus Corporation | Low pH pharmaceutical compositions of recombinant β-interferon |
CA1338839C (en) * | 1988-01-29 | 1997-01-14 | Yoshio Sasaki | Controlled release formulation |
US5078997A (en) * | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
US5165921A (en) * | 1989-01-23 | 1992-11-24 | National Geno Sciences, Inc. | Method for treating condyloma acuminatum with interferon |
IT1240314B (it) * | 1989-09-28 | 1993-12-07 | Immunobiology Research Institutes, Inc. | Formulazioni acquose stabilizzate di piccoli peptidi. |
CA2120950A1 (en) * | 1991-10-11 | 1993-04-15 | Mark C. Gillies | Treating ophthalmic fibrosis using interferon-alpha |
US5863530A (en) * | 1991-10-11 | 1999-01-26 | Spruson & Ferguson | Treating ophthalmic fibrosis using interferon-α |
AU669132B2 (en) * | 1991-10-11 | 1996-05-30 | Mark Cedric Gillies | Treating ophthalmic fibrosis using interferon-alpha |
US5236707A (en) * | 1991-11-08 | 1993-08-17 | Dallas Biotherapeutics, Inc. | Stabilization of human interferon |
LT3987B (en) | 1992-02-17 | 1996-06-25 | Fermentas Biotech Inst | Stabilized interferon compositions |
US5358708A (en) * | 1993-01-29 | 1994-10-25 | Schering Corporation | Stabilization of protein formulations |
US6270757B1 (en) * | 1994-04-21 | 2001-08-07 | Genetics Institute, Inc. | Formulations for IL-11 |
US6399296B1 (en) * | 1994-07-20 | 2002-06-04 | The General Hospital Corporation | Interaction trap systems for detecting protein interactions |
US5766582A (en) * | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
AU695129B2 (en) * | 1995-02-06 | 1998-08-06 | Genetics Institute, Llc | Formulations for IL-12 |
US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
US6540993B1 (en) * | 1995-06-27 | 2003-04-01 | Wyeth | Method of treating inflammatory bowel disease using a topical formulation of IL-11 |
US6126933A (en) * | 1995-06-27 | 2000-10-03 | Genetics Institute | Methods of treating inflammatory bowel diseases by administering IL-11 |
EE04223B1 (et) * | 1996-12-24 | 2004-02-16 | Biogen, Incorporated | Interferooni stabiilne vedelkompositsioon, mis sisaldab aminohappeid |
US20030190307A1 (en) | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
DE59805732D1 (de) † | 1997-09-23 | 2002-10-31 | Rentschler Biotech Gmbh | Flüssige interferon-beta-formulierungen |
US7230014B1 (en) | 1997-10-14 | 2007-06-12 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
JP3459407B2 (ja) * | 1997-10-14 | 2003-10-20 | エーザイ株式会社 | 安定剤としてグリシンを含む製薬学的製剤 |
US7129390B2 (en) * | 1997-10-16 | 2006-10-31 | Avigenics, Inc | Poultry Derived Glycosylated Interferon Alpha 2b |
US7511120B2 (en) * | 1997-10-16 | 2009-03-31 | Synageva Biopharma Corp. | Glycosylated G-CSF obtained from a transgenic chicken |
US20040019923A1 (en) * | 1997-10-16 | 2004-01-29 | Ivarie Robert D. | Exogenous proteins expressed in avians and their eggs |
US20090074718A1 (en) * | 1997-10-16 | 2009-03-19 | Ivarie Robert D | Avian derived erythropoietin |
US8563803B2 (en) * | 1997-10-16 | 2013-10-22 | Synageva Biopharma Corp. | Method of making protein in an egg of a transgenic chicken |
US20030166525A1 (en) * | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
US6281337B1 (en) | 1998-11-12 | 2001-08-28 | Schering Corporation | Methods for conversion of protein isoforms |
DE69942655D1 (de) | 1998-11-12 | 2010-09-16 | Schering Corp | Verfahren zur Umwandlung von Interferon-Isoformen und daraus hergestellte Produkte |
WO2001044441A1 (en) * | 1999-12-14 | 2001-06-21 | Thermo Biostar, Inc. | Stabilizing diluent for polypeptides and antigens |
JP2004537964A (ja) | 2000-11-03 | 2004-12-24 | ペストカ バイオメディカル ラボラトリーズ インコーポレイテッド | インターフェロン、それに関する使用及び組成物 |
CA2433037C (en) | 2000-12-28 | 2010-12-21 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
AR034749A1 (es) * | 2001-07-09 | 2004-03-17 | Schering Ag | Formulaciones de interferon beta humano |
CA2753899C (en) | 2002-01-18 | 2014-03-25 | Biogen Idec Ma Inc. | Polyalkylene glycol with moiety for conjugating biologically active compounds |
US6830744B2 (en) | 2002-05-31 | 2004-12-14 | Aradigm Corporation | Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b |
US20050232899A1 (en) * | 2002-05-31 | 2005-10-20 | Aradigm Corporation | Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b |
US7803362B2 (en) * | 2003-01-24 | 2010-09-28 | Synageva Biopharma Corp. | Glycosylated interferon alpha |
RS20050737A (en) * | 2003-04-02 | 2007-11-15 | Ares Trading S.A., | Liquid pharmaceutical formulations fish and lh together with a non- ionic surfactant |
US7740884B2 (en) * | 2003-06-20 | 2010-06-22 | Ares Trading S.A. | Freeze-dried FSH/LH formulations |
DE602005022895D1 (de) * | 2004-08-12 | 2010-09-23 | Schering Corp | Stabile pegylierte interferon-formulierung |
WO2006091038A1 (en) * | 2005-02-25 | 2006-08-31 | Medigenes Co., Ltd. | Pharmaceutical composition for treating avellino cornea dystrophy comprising blood plasma or serum |
US8124732B2 (en) | 2005-06-24 | 2012-02-28 | Synageva Biopharma Corp. | Composition comprising isolated human CTLA4-Fc fusion protein produced in a transgenic chicken |
US20070003564A1 (en) * | 2005-06-30 | 2007-01-04 | Hurley John K | Diluent for immunohistochemistry |
WO2008048228A2 (en) * | 2005-08-12 | 2008-04-24 | Department Of The Army | Glycine stabilized lyophilized plasma |
CU23432B6 (es) | 2005-11-02 | 2009-10-16 | Ct Ingenieria Genetica Biotech | Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras |
US7812127B2 (en) | 2006-03-17 | 2010-10-12 | Synageva Biopharma Corp. | Glycosylated human G-CSF |
US20090105462A1 (en) * | 2006-11-09 | 2009-04-23 | Ivarie Robert D | Glycosylated erythropoietin |
PT2097068E (pt) * | 2006-11-24 | 2013-10-23 | Cadila Healthcare Ltd | Formulações de conjugados de peg-interferão alfa |
CA2671570A1 (en) | 2007-01-26 | 2008-07-31 | Synageva Biopharma Corp. | Transgene expression in avians |
MX2009013886A (es) | 2007-06-25 | 2010-01-27 | Amgen Inc | Composiciones de agentes de aglutinacion especifica al factor de crecimiento de los hepatocitos. |
US20100297081A1 (en) * | 2007-12-18 | 2010-11-25 | Huang Yanshan | Pharmaceutical formulation containing recombinant human serum albumin-interferon alpha fusion protein |
TR201809898T4 (tr) | 2009-11-03 | 2018-07-23 | Grifols Therapeutics Llc | Alfa-1 protei̇naz i̇nhi̇bi̇törüne yöneli̇k bi̇leşi̇m, yöntem ve ki̇t. |
CN102762196B (zh) | 2009-11-24 | 2014-05-14 | 基立福疗法公司 | 冻干方法、组合物和试剂盒 |
US20130008191A1 (en) * | 2011-07-07 | 2013-01-10 | Suchak Naresh J | Methods for freezing and thawing proteins |
WO2017030563A1 (en) | 2014-08-19 | 2017-02-23 | Biogen Ma Inc | Pegylation method |
CN106421755A (zh) * | 2016-11-03 | 2017-02-22 | 广州凯耀资产管理有限公司 | 一种干扰素组合物及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2553497A (en) * | 1946-02-04 | 1951-05-15 | L Inst De Serotherapie Hemopoi | Hemostatic composition of thrombin and glycocoll |
US2806815A (en) * | 1955-04-12 | 1957-09-17 | Ortho Pharma Corp | Stabilized hyaluronidase |
GB866423A (en) * | 1958-03-21 | 1961-04-26 | Armour & Co | Improvements in or relating to chymotrypsin solutions |
US3016398A (en) * | 1959-04-06 | 1962-01-09 | Staley Mfg Co A E | Stabilized phytic acid solutions and methods of preparation thereof |
GB900115A (en) * | 1960-06-15 | 1962-07-04 | Armour & Co | Improvements in or relating to trypsin solutions |
JPS5495795A (en) * | 1978-01-13 | 1979-07-28 | Toray Ind Inc | Production of interferon |
IN150740B (pt) * | 1978-11-24 | 1982-12-04 | Hoffmann La Roche | |
JPS55102519A (en) * | 1979-01-31 | 1980-08-05 | Green Cross Corp:The | Stabilization of interferon |
US4198479A (en) * | 1979-03-30 | 1980-04-15 | Merck & Co., Inc. | Replacement of animal serum proteins by human albumin for growth and interferon production by Namalva cells |
US4252791A (en) * | 1979-10-19 | 1981-02-24 | The Medical College Of Wisconsin, Inc. | Interferon stabilization |
US4337242A (en) * | 1980-02-05 | 1982-06-29 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
-
1982
- 1982-12-15 DE DE8282111665T patent/DE3262575D1/de not_active Expired
- 1982-12-15 EP EP82111665A patent/EP0082481B2/en not_active Expired - Lifetime
- 1982-12-20 NZ NZ202856A patent/NZ202856A/en unknown
- 1982-12-20 PH PH28296A patent/PH19869A/en unknown
- 1982-12-20 IL IL67517A patent/IL67517A/xx not_active IP Right Cessation
- 1982-12-20 NO NO82824285A patent/NO161036C/no not_active IP Right Cessation
- 1982-12-20 FI FI824366A patent/FI70794C/fi not_active IP Right Cessation
- 1982-12-20 AU AU91688/82A patent/AU558966B2/en not_active Expired
- 1982-12-21 DK DK565882A patent/DK158873C/da not_active IP Right Cessation
- 1982-12-21 PT PT76013A patent/PT76013B/pt unknown
- 1982-12-21 CA CA000418237A patent/CA1207665A/en not_active Expired
- 1982-12-21 IE IE3046/82A patent/IE54468B1/en not_active IP Right Cessation
- 1982-12-21 OA OA57876A patent/OA07282A/xx unknown
- 1982-12-22 HU HU824137A patent/HU190649B/hu unknown
-
1983
- 1983-09-16 US US06/532,886 patent/US4496537A/en not_active Expired - Lifetime
-
1987
- 1987-08-27 SG SG706/87A patent/SG70687G/en unknown
- 1987-12-10 HK HK944/87A patent/HK94487A/xx not_active IP Right Cessation
- 1987-12-30 MY MY705/87A patent/MY8700705A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MY8700705A (en) | 1987-12-31 |
PH19869A (en) | 1986-08-13 |
FI70794B (fi) | 1986-07-18 |
NO824285L (no) | 1983-06-24 |
PT76013A (en) | 1983-01-01 |
IE823046L (en) | 1983-06-23 |
HK94487A (en) | 1987-12-18 |
FI70794C (fi) | 1986-10-27 |
DE3262575D1 (en) | 1985-04-18 |
EP0082481B1 (en) | 1985-03-13 |
HU190649B (en) | 1986-09-29 |
DK158873B (da) | 1990-07-30 |
IL67517A (en) | 1988-11-30 |
IL67517A0 (en) | 1983-05-15 |
OA07282A (fr) | 1984-11-30 |
AU558966B2 (en) | 1987-02-19 |
DK158771B (da) | 1990-07-16 |
NZ202856A (en) | 1985-12-13 |
AU9168882A (en) | 1983-06-30 |
EP0082481A1 (en) | 1983-06-29 |
SG70687G (en) | 1988-02-19 |
DK158873C (da) | 1990-12-31 |
FI824366A0 (fi) | 1982-12-20 |
EP0082481B2 (en) | 1990-09-12 |
FI824366L (fi) | 1983-06-24 |
CA1207665A (en) | 1986-07-15 |
DK565882A (da) | 1983-06-24 |
NO161036B (no) | 1989-03-20 |
NO161036C (no) | 1989-06-28 |
US4496537A (en) | 1985-01-29 |
IE54468B1 (en) | 1989-10-25 |
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