PT1385512E - Utilizacao de derivados de piridoindolona para preparacao de medicamentos anticancerigenos - Google Patents

Utilizacao de derivados de piridoindolona para preparacao de medicamentos anticancerigenos

Info

Publication number: PT1385512E
Authority: PT; Portugal
Prior art keywords: pyridindolone; anticancerigene; medicines; derivatives; preparation
Prior art date: 2001-04-27

Application number

PT02732841T

Other languages

English (en)

Inventor

Bernard Bourrie

Pierre Casellas

Derocq Jean-Marie

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-27

Filing date

2002-04-26

Publication date

2006-05-31

2002-04-26 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2006-05-31 Publication of PT1385512E publication Critical patent/PT1385512E/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PT02732841T 2001-04-27 2002-04-26 Utilizacao de derivados de piridoindolona para preparacao de medicamentos anticancerigenos PT1385512E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0105843A FR2823975B1 (fr)	2001-04-27	2001-04-27	Nouvelle utilisation de pyridoindolone

Publications (1)

Publication Number	Publication Date
PT1385512E true PT1385512E (pt)	2006-05-31

Family

ID=8862882

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT02735502T PT1385513E (pt)	2001-04-27	2002-04-26	Associações farmacêuticas à base de derivados de piridoindolona e agentes anticancerígenos
PT02732841T PT1385512E (pt)	2001-04-27	2002-04-26	Utilizacao de derivados de piridoindolona para preparacao de medicamentos anticancerigenos

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PT02735502T PT1385513E (pt)	2001-04-27	2002-04-26	Associações farmacêuticas à base de derivados de piridoindolona e agentes anticancerígenos

Country Status (34)

Country	Link
US (3)	US7524857B2 (pt)
EP (2)	EP1385513B1 (pt)
JP (2)	JP2004531538A (pt)
KR (1)	KR100847413B1 (pt)
CN (2)	CN1505511A (pt)
AR (1)	AR034313A1 (pt)
AT (2)	ATE314070T1 (pt)
BG (2)	BG108261A (pt)
BR (1)	BR0209138A (pt)
CA (2)	CA2444334A1 (pt)
CY (1)	CY1105813T1 (pt)
CZ (2)	CZ299465B6 (pt)
DE (2)	DE60208365T2 (pt)
DK (2)	DK1385512T3 (pt)
EA (1)	EA005930B1 (pt)
EE (2)	EE200300465A (pt)
ES (2)	ES2254683T3 (pt)
FR (1)	FR2823975B1 (pt)
HK (2)	HK1059895A1 (pt)
HU (2)	HUP0400745A2 (pt)
IL (4)	IL158312A0 (pt)
IS (1)	IS2441B (pt)
MX (1)	MXPA03009639A (pt)
NO (2)	NO20034787L (pt)
NZ (1)	NZ528671A (pt)
PL (2)	PL366910A1 (pt)
PT (2)	PT1385513E (pt)
RS (2)	RS50790B (pt)
RU (1)	RU2292888C9 (pt)
SK (2)	SK13242003A3 (pt)
TW (1)	TWI252104B (pt)
UA (1)	UA74876C2 (pt)
WO (2)	WO2002087575A1 (pt)
ZA (1)	ZA200307785B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2823975B1 (fr) *	2001-04-27	2003-05-30	Sanofi Synthelabo	Nouvelle utilisation de pyridoindolone
US7456193B2 (en)	2002-10-23	2008-11-25	Sanofi-Aventis	Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2846329B1 (fr) *	2002-10-23	2004-12-03	Sanofi Synthelabo	Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2869316B1 (fr) *	2004-04-21	2006-06-02	Sanofi Synthelabo	Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr)	2005-10-20	2008-06-27	Sanofi Aventis Sa	Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1268772A (en) *	1968-03-15	1972-03-29	Glaxo Lab Ltd	NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) *	1978-06-05	1981-04-21	Sumitomo Chemical Company, Limited	7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) *	1979-07-10	1981-05-30	Ленинградский Химико-Фармацевтическийинститут	Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
SU833972A1 (ru)	1979-10-26	1981-05-30	Институт Физико-Органической Химиии Углехимии Ah Украинской Ccp	Имидазо(4,5-с)пиридиний иодиды вКАчЕСТВЕ пРОМЕжуТОчНыХ пРОдуКТОВ дл СиНТЕзА фуНгицидОВ
FR2595701B1 (fr) *	1986-03-17	1988-07-01	Sanofi Sa	Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
US5035252A (en) *	1990-12-14	1991-07-30	Mondre Steven J	Nicotine-containing dental floss
CA2187626C (en) *	1994-04-13	2009-11-03	Michael G. Kaplitt	Aav-mediated delivery of dna to cells of the nervous system
DE19502753A1 (de) *	1995-01-23	1996-07-25	Schering Ag	Neue 9H-Pyrido[3,4-b]indol-Derivate
US6486177B2 (en) *	1995-12-04	2002-11-26	Celgene Corporation	Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
FR2765581B1 (fr) *	1997-07-03	1999-08-06	Synthelabo	Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
FR2765582B1 (fr)	1997-07-03	1999-08-06	Synthelabo	Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
AU3375999A (en) *	1998-04-02	1999-10-25	Neurogen Corporation	Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino(2,3-b)indole and 5,6,7,8-tetrahydro-9h-pyrimidino(4,5-b)indole derivatives: crf1 specific ligands
IT1313592B1 (it)	1999-08-03	2002-09-09	Novuspharma Spa	Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) *	2001-03-30	2002-10-24	Gerald Minuk	Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) *	2001-04-27	2003-05-30	Sanofi Synthelabo	Nouvelle utilisation de pyridoindolone
FR2846330B1 (fr)	2002-10-23	2004-12-03	Sanofi Synthelabo	Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
FR2846329B1 (fr)	2002-10-23	2004-12-03	Sanofi Synthelabo	Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
US6958347B2 (en)	2002-12-18	2005-10-25	Pfizer Inc.	Aminophenanthridinone and aminophenanthridine as NPY-5 antagonists
FR2869316B1 (fr)	2004-04-21	2006-06-02	Sanofi Synthelabo	Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr)	2005-10-20	2008-06-27	Sanofi Aventis Sa	Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

2001
- 2001-04-27 FR FR0105843A patent/FR2823975B1/fr not_active Expired - Fee Related
2002
- 2002-04-26 WO PCT/FR2002/001450 patent/WO2002087575A1/fr active IP Right Grant
- 2002-04-26 BR BR0209138-0A patent/BR0209138A/pt not_active IP Right Cessation
- 2002-04-26 CZ CZ20032910A patent/CZ299465B6/cs not_active IP Right Cessation
- 2002-04-26 EE EEP200300465A patent/EE200300465A/xx unknown
- 2002-04-26 CN CNA028089596A patent/CN1505511A/zh active Pending
- 2002-04-26 HU HU0400745A patent/HUP0400745A2/hu unknown
- 2002-04-26 CN CNB028088980A patent/CN1240382C/zh not_active Expired - Fee Related
- 2002-04-26 DK DK02732841T patent/DK1385512T3/da active
- 2002-04-26 CZ CZ20032909A patent/CZ295224B6/cs not_active IP Right Cessation
- 2002-04-26 UA UA2003109248A patent/UA74876C2/uk unknown
- 2002-04-26 US US10/476,321 patent/US7524857B2/en not_active Expired - Lifetime
- 2002-04-26 PL PL02366910A patent/PL366910A1/xx unknown
- 2002-04-26 CA CA002444334A patent/CA2444334A1/fr not_active Abandoned
- 2002-04-26 RU RU2003130376/15A patent/RU2292888C9/ru active
- 2002-04-26 EP EP02735502A patent/EP1385513B1/fr not_active Expired - Lifetime
- 2002-04-26 EP EP02732841A patent/EP1385512B1/fr not_active Expired - Lifetime
- 2002-04-26 JP JP2002584920A patent/JP2004531538A/ja active Pending
- 2002-04-26 PL PL02366916A patent/PL366916A1/xx not_active IP Right Cessation
- 2002-04-26 NZ NZ528671A patent/NZ528671A/en unknown
- 2002-04-26 AT AT02732841T patent/ATE314070T1/de not_active IP Right Cessation
- 2002-04-26 DE DE60208365T patent/DE60208365T2/de not_active Expired - Lifetime
- 2002-04-26 PT PT02735502T patent/PT1385513E/pt unknown
- 2002-04-26 TW TW091108716A patent/TWI252104B/zh not_active IP Right Cessation
- 2002-04-26 EE EEP200300466A patent/EE200300466A/xx unknown
- 2002-04-26 RS YUP-834/03A patent/RS50790B/sr unknown
- 2002-04-26 SK SK1324-2003A patent/SK13242003A3/sk unknown
- 2002-04-26 IL IL15831202A patent/IL158312A0/xx unknown
- 2002-04-26 EA EA200301062A patent/EA005930B1/ru not_active IP Right Cessation
- 2002-04-26 MX MXPA03009639A patent/MXPA03009639A/es active IP Right Grant
- 2002-04-26 RS YUP-839/03A patent/RS50791B/sr unknown
- 2002-04-26 CA CA002443012A patent/CA2443012C/fr not_active Expired - Fee Related
- 2002-04-26 HU HU0400744A patent/HUP0400744A2/hu unknown
- 2002-04-26 DK DK02735502T patent/DK1385513T3/da active
- 2002-04-26 ES ES02732841T patent/ES2254683T3/es not_active Expired - Lifetime
- 2002-04-26 PT PT02732841T patent/PT1385512E/pt unknown
- 2002-04-26 AT AT02735502T patent/ATE338548T1/de not_active IP Right Cessation
- 2002-04-26 IL IL15826602A patent/IL158266A0/xx unknown
- 2002-04-26 KR KR1020037013925A patent/KR100847413B1/ko not_active IP Right Cessation
- 2002-04-26 WO PCT/FR2002/001449 patent/WO2002087574A2/fr active IP Right Grant
- 2002-04-26 AR ARP020101521A patent/AR034313A1/es unknown
- 2002-04-26 ES ES02735502T patent/ES2271264T3/es not_active Expired - Lifetime
- 2002-04-26 US US10/476,322 patent/US6967203B2/en not_active Expired - Lifetime
- 2002-04-26 JP JP2002584919A patent/JP2004528343A/ja active Pending
- 2002-04-26 DE DE60214533T patent/DE60214533T2/de not_active Expired - Lifetime
- 2002-04-26 SK SK1325-2003A patent/SK13252003A3/sk unknown
2003
- 2003-10-02 IL IL158266A patent/IL158266A/en not_active IP Right Cessation
- 2003-10-06 ZA ZA200307785A patent/ZA200307785B/en unknown
- 2003-10-08 IL IL158312A patent/IL158312A/en not_active IP Right Cessation
- 2003-10-09 IS IS6984A patent/IS2441B/is unknown
- 2003-10-13 BG BG108261A patent/BG108261A/bg unknown
- 2003-10-13 BG BG108260A patent/BG108260A/bg unknown
- 2003-10-24 NO NO20034787A patent/NO20034787L/no not_active Application Discontinuation
- 2003-10-24 NO NO20034785A patent/NO20034785L/no not_active Application Discontinuation
2004
- 2004-04-20 HK HK04102775A patent/HK1059895A1/xx not_active IP Right Cessation
- 2004-05-03 HK HK04103103A patent/HK1060066A1/xx not_active IP Right Cessation
2005
- 2005-08-15 US US11/204,275 patent/US7160895B2/en not_active Expired - Lifetime
2006
- 2006-11-30 CY CY20061101725T patent/CY1105813T1/el unknown

Also Published As

Publication number	Publication date
EA200301062A1 (ru)	2004-04-29
SK13252003A3 (sk)	2004-03-02
UA74876C2 (en)	2006-02-15
HUP0400744A2 (hu)	2004-06-28
PL366910A1 (en)	2005-02-07
EP1385512A2 (fr)	2004-02-04
CZ20032909A3 (en)	2004-06-16
IL158312A0 (en)	2004-05-12
NO20034785D0 (no)	2003-10-24
US7524857B2 (en)	2009-04-28
US6967203B2 (en)	2005-11-22
IS2441B (is)	2008-11-15
YU83403A (sh)	2006-08-17
CZ20032910A3 (en)	2004-07-14
BG108261A (bg)	2004-12-30
CA2443012C (fr)	2009-07-28
ES2271264T3 (es)	2007-04-16
IL158266A0 (en)	2004-05-12
EP1385513B1 (fr)	2006-09-06
HK1059895A1 (en)	2004-07-23
ES2254683T3 (es)	2006-06-16
NO20034787D0 (no)	2003-10-24
DE60208365D1 (de)	2006-02-02
PT1385513E (pt)	2007-01-31
IS6984A (is)	2003-10-09
ATE338548T1 (de)	2006-09-15
NZ528671A (en)	2004-06-25
RS50790B (sr)	2010-08-31
DK1385512T3 (da)	2006-05-22
KR100847413B1 (ko)	2008-07-18
HK1060066A1 (en)	2004-07-30
SK13242003A3 (sk)	2004-03-02
BG108260A (bg)	2004-12-30
CA2444334A1 (fr)	2002-11-07
DK1385513T3 (da)	2007-01-15
PL366916A1 (en)	2005-02-07
RS50791B (sr)	2010-08-31
CZ295224B6 (cs)	2005-06-15
KR20040015138A (ko)	2004-02-18
ZA200307785B (en)	2004-10-06
EA005930B1 (ru)	2005-08-25
WO2002087574A3 (fr)	2003-02-13
US20050272760A1 (en)	2005-12-08
US20040122027A1 (en)	2004-06-24
TWI252104B (en)	2006-04-01
DE60214533D1 (de)	2006-10-19
CY1105813T1 (el)	2011-02-02
EE200300466A (et)	2003-12-15
NO20034787L (no)	2003-12-23
JP2004528343A (ja)	2004-09-16
HUP0400745A2 (hu)	2004-08-30
MXPA03009639A (es)	2004-06-30
EP1385512B1 (fr)	2005-12-28
DE60214533T2 (de)	2007-06-21
WO2002087575A1 (fr)	2002-11-07
IL158266A (en)	2009-09-01
IL158312A (en)	2009-09-01
EE200300465A (et)	2003-12-15
AR034313A1 (es)	2004-02-18
CA2443012A1 (en)	2002-11-07
JP2004531538A (ja)	2004-10-14
CZ299465B6 (cs)	2008-08-06
EP1385513A1 (fr)	2004-02-04
NO20034785L (no)	2003-12-23
RU2292888C9 (ru)	2007-06-20
YU83903A (sh)	2006-08-17
FR2823975B1 (fr)	2003-05-30
CN1240382C (zh)	2006-02-08
BR0209138A (pt)	2004-06-08
RU2003130376A (ru)	2005-04-10
CN1505510A (zh)	2004-06-16
CN1505511A (zh)	2004-06-16
US20040122036A1 (en)	2004-06-24
DE60208365T2 (de)	2006-09-07
ATE314070T1 (de)	2006-01-15
FR2823975A1 (fr)	2002-10-31
RU2292888C2 (ru)	2007-02-10
WO2002087574A2 (fr)	2002-11-07
US7160895B2 (en)	2007-01-09

Publication	Publication Date	Title
NO20033384L (no)	2003-09-25	Farmasoytisk formulering
NO20033785D0 (no)	2003-08-26	Farmasöytisk formulering
NO20033556L (no)	2003-10-09	Farmasöytiske formuleringer
NO20042680L (no)	2004-06-25	Fremgangsmater for fremstilling av O-demetylvenflaxine
FI20011478A0 (fi)	2001-07-05	Farmaseuttinen koostumus
EE05020B1 (et)	2008-06-16	Glburiidi ravimkoostis
NO20035627D0 (no)	2003-12-15	Farmasöytisk formulering
NO20035315D0 (no)	2003-11-28	Farmasöytiske kombinasjoner
FI20011889A (fi)	2003-03-27	Menetelmä ksylitolin valmistamiseksi
DE60203537D1 (de)	2005-05-04	5ht1-rezeptoragonist enthaltendes arzneimittel
DK1475379T3 (da)	2007-09-03	Anvendelse af scopinesterderivater til fremstilling af lægemidler
NO20041485L (no)	2004-04-13	Farmasoytisk formulering omfattende (R)-bicalutamid
PT1385512E (pt)	2006-05-31	Utilizacao de derivados de piridoindolona para preparacao de medicamentos anticancerigenos
AR028400A1 (es)	2003-05-07	Procedimiento para la preparacion de compuestos halogenados de hidroxidifenilo
FI20012242A0 (fi)	2001-11-19	Uudet farmaseuttiset yhdisteet
AR028111A1 (es)	2003-04-23	Procedimiento para la produccion de isocianatos
NO20041236L (no)	2004-03-24	Farmasoytisk formulering
ITMI20012131A0 (it)	2001-10-16	Procedimento per la preparazione di alo-benzonitrili
ES1049731Y (es)	2002-05-16	Dispositivo para la administracion de farmacos.
SE0102572D0 (sv)	2001-07-19	Pharmaceutical formulation
SE0101326D0 (sv)	2001-04-12	Pharmaceutical formulation
SE0101325D0 (sv)	2001-04-12	Pharmaceutical formulation
SE0101171D0 (sv)	2001-04-02	Pharmaceutical formulation
SE0103565D0 (sv)	2001-10-25	Pharmaceutical formulation
SE0102957D0 (sv)	2001-09-04	Pharmaceutical formulation