PT1144026E - Sistema para separacao sanguinea util, em particular, para concentracoes de celulas estaminais hematopoieticas - Google Patents

Sistema para separacao sanguinea util, em particular, para concentracoes de celulas estaminais hematopoieticas

Info

Publication number
PT1144026E
PT1144026E PT99959629T PT99959629T PT1144026E PT 1144026 E PT1144026 E PT 1144026E PT 99959629 T PT99959629 T PT 99959629T PT 99959629 T PT99959629 T PT 99959629T PT 1144026 E PT1144026 E PT 1144026E
Authority
PT
Portugal
Prior art keywords
components
biological fluid
processing chamber
stem cells
separated
Prior art date
Application number
PT99959629T
Other languages
English (en)
Inventor
Claude Fell
Original Assignee
Biosafe Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosafe Sa filed Critical Biosafe Sa
Publication of PT1144026E publication Critical patent/PT1144026E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3698Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0485Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PT99959629T 1998-12-24 1999-12-24 Sistema para separacao sanguinea util, em particular, para concentracoes de celulas estaminais hematopoieticas PT1144026E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9802114 1998-12-24

Publications (1)

Publication Number Publication Date
PT1144026E true PT1144026E (pt) 2004-12-31

Family

ID=11004802

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99959629T PT1144026E (pt) 1998-12-24 1999-12-24 Sistema para separacao sanguinea util, em particular, para concentracoes de celulas estaminais hematopoieticas

Country Status (11)

Country Link
US (1) US6733433B1 (pt)
EP (1) EP1144026B1 (pt)
JP (1) JP4514338B2 (pt)
CN (1) CN1182882C (pt)
AT (1) ATE271890T1 (pt)
AU (1) AU1675600A (pt)
DE (1) DE69919029T2 (pt)
ES (1) ES2224726T3 (pt)
HK (1) HK1041454B (pt)
PT (1) PT1144026E (pt)
WO (1) WO2000038762A1 (pt)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10134913C2 (de) 2001-07-18 2003-06-26 Hiberna Ag Vorrichtung und Verfahren zur Blutpräparation
EP1454135B1 (en) * 2001-12-05 2009-01-21 CaridianBCT, Inc. Methods and apparatus for separation of blood components
US8062837B2 (en) 2002-02-14 2011-11-22 Stemcyte, Inc. Plasma-depleted, not erythrocyte-depleted, cord blood compositions and method of making
US7241281B2 (en) 2002-04-08 2007-07-10 Thermogenesis Corporation Blood component separation method and apparatus
US20040256331A1 (en) * 2002-10-04 2004-12-23 Arking E. James System and method for fractionation of a centrifuged sample
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
CA2530416C (en) 2003-06-27 2015-08-25 Ethicon, Incorporated Postpartum cells derived from placental tissue, and methods of making and using the same
ITMI20031715A1 (it) 2003-09-05 2005-03-06 Dideco Spa Dispositivo di comando nella raccolta differenziata dei
US7060018B2 (en) 2003-09-11 2006-06-13 Cobe Cardiovascular, Inc. Centrifuge apparatus for processing blood
WO2005032619A1 (ja) * 2003-10-02 2005-04-14 Terumo Kabushiki Kaisha 血液処理回路の製造方法およびフィルターユニット
US7052451B2 (en) * 2004-04-14 2006-05-30 Wagner Development, Inc. Conical piston solids discharge centrifugal separator
US7261683B2 (en) 2004-04-14 2007-08-28 Wagner Development, Inc. Conical piston solids discharge and pumping centrifugal separator
WO2006100651A1 (en) * 2005-03-23 2006-09-28 Biosafe S.A. Integrated system for collecting, processing and transplanting cell subsets, including adult stem cells, for regenerative medicine
US7364657B2 (en) * 2005-03-31 2008-04-29 Abbott Cardiovascular Systems Inc. Integrated system for on-site cell acquisition, processing, and delivery
US8048619B2 (en) 2005-06-02 2011-11-01 Stemcyte, Inc. Method of treating a hematopoietic associated disease or disorder with plasma-depleted, but not erythrocyte-depleted cord blood compositions
JP5175184B2 (ja) * 2005-06-22 2013-04-03 テルモ ビーシーティー、インコーポレーテッド 個別容量の複合液体を分離するための装置および方法
US20100210441A1 (en) * 2005-06-22 2010-08-19 Caridianbct, Inc. Apparatus And Method For Separating Discrete Volumes Of A Composite Liquid
US7618361B2 (en) * 2005-09-01 2009-11-17 Wagner Development, Inc. Gas driven solids discharge and pumping piston for a centrifugal separator
US7628749B2 (en) 2005-09-01 2009-12-08 Wagner Development Inc. Solids recovery using cross-flow microfilter and automatic piston discharge centrifuge
US20070119508A1 (en) * 2005-11-29 2007-05-31 West Richard L Fluid Flow Diversion Valve and Blood Collection System Employing Same
PL1971681T3 (pl) 2005-12-16 2018-01-31 Depuy Synthes Products Inc Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej
ES2671355T3 (es) 2005-12-29 2018-06-06 Anthrogenesis Corporation Poblaciones de células madre placentarias
US7998052B2 (en) * 2006-03-07 2011-08-16 Jacques Chammas Rotor defining a fluid separation chamber of varying volume
GB0608451D0 (en) * 2006-04-28 2006-06-07 Ge Healthcare Bio Sciences Ab Centrifugal separation system
EP2077871A2 (en) * 2006-10-20 2009-07-15 CaridianBCT Biotechnologies, LLC Methods for washing a red blood cell component and for removing prions therefrom
US20080108954A1 (en) * 2006-11-02 2008-05-08 Jean-Marie Mathias Flow Controllers
US20080108955A1 (en) * 2006-11-02 2008-05-08 Blickhan Bryan J Flow Controllers
CN103356711A (zh) 2007-02-12 2013-10-23 人类起源公司 利用胎盘干细胞治疗炎性疾病
RS53841B1 (en) 2007-09-28 2015-06-30 Anthrogenesis Corporation TUMOR SUPPRESSION USING HUMAN PLACENTAL PERFUSES AND INTERMEDIATE CELLS KILLED ORIGINATING IN HUMAN PLACENTA
DE102007059841B3 (de) * 2007-12-12 2009-04-23 Ab Skf Biokompatibles Verbindungsmodul für einen Fluidbehälter
US20090218535A1 (en) * 2008-02-27 2009-09-03 Andres Pasko Flow controllers for fluid circuits
US7976796B1 (en) * 2008-07-03 2011-07-12 Emcyte Corp. Centrifuge tube for separating and aspirating biological components
PE20110400A1 (es) 2008-08-20 2011-06-22 Anthrogenesis Corp Composiciones mejoradas de celulas y metodos para preparar las mismas
DE102008047068B4 (de) * 2008-09-12 2015-02-26 Walter Pobitschka Verfahren und Vorrichtung zur Trennung von Blut unter Einsatz einer Zentrifuge
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
JP5688374B2 (ja) 2008-12-29 2015-03-25 ワグナー デベロップメント, インコーポレイテッド 使い捨て式接触要素を備えた固体排出遠心分離機
JP2010193879A (ja) * 2009-01-27 2010-09-09 Jms Co Ltd 臍帯血造血幹細胞の増殖制御方法およびその用途
WO2010138895A2 (en) 2009-05-29 2010-12-02 Neil Francis Duffy Apparatus and methods for aspirating and separating components of different densities from a physiological fluid containing cells
EP2451501B1 (en) * 2009-07-06 2013-05-01 Terumo BCT, Inc. Apparatus and method for automatically loading washing solution in a multi-unit blood processor
DE102009040525B4 (de) * 2009-09-08 2015-02-05 Andreas Hettich Gmbh & Co. Kg Zentrifuge zum Trennen von Vollblut in Blutkomponenten, sowie fluidisch kommunizierende Behälter zum Einsetzen in die Zentrifuge, sowie Verfahren zur Gewinnung eines hochangereichten Thrombozytenkonzentrats aus Vollblut
CA2777718A1 (en) 2009-10-16 2011-04-21 University Of Medicine And Dentistry Of New Jersey Closed system separation of adherent bone marrow stem cells for regenerative medicine applications
KR101049201B1 (ko) * 2009-10-29 2011-07-14 토자이홀딩스 주식회사 말초혈액 내의 조혈 줄기세포 및 중간엽 줄기세포의 추출을 위한 바이오 디바이스
US9034280B2 (en) * 2009-12-16 2015-05-19 General Electric Corporation High-throughput methods and systems for processing biological materials
KR200458000Y1 (ko) * 2010-01-07 2012-01-16 (주)아모레퍼시픽 잔량확인이 가능한 에어리스펌프를 갖는 화장품용기
EP2529007B1 (en) 2010-01-26 2017-07-12 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells
CN107699541A (zh) 2010-04-07 2018-02-16 人类起源公司 使用胎盘干细胞的血管生成
US8840535B2 (en) 2010-05-27 2014-09-23 Terumo Bct, Inc. Multi-unit blood processor with temperature sensing
US9028388B2 (en) 2010-06-07 2015-05-12 Terumo Bct, Inc. Multi-unit blood processor with volume prediction
KR20190108599A (ko) 2010-07-13 2019-09-24 안트로제네시스 코포레이션 천연 킬러 세포의 생성 방법
CA2805102A1 (en) * 2010-08-09 2012-02-16 Kci Licensing, Inc. System and method for measuring pressure applied by a piezo-electric pump
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
WO2012092485A1 (en) 2010-12-31 2012-07-05 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
EP3443968A1 (en) 2011-06-01 2019-02-20 Celularity, Inc. Treatment of pain using placental stem cells
EP2826503B1 (en) * 2012-03-13 2017-05-03 Terumo Kabushiki Kaisha Blood components separation device, and centrifugal separator
US20130252227A1 (en) * 2012-03-20 2013-09-26 Fenwal, Inc. Apparatus and Method for Providing Cryopreserved ECP-Treated Mononuclear Cells
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9022950B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9733805B2 (en) 2012-06-26 2017-08-15 Terumo Bct, Inc. Generating procedures for entering data prior to separating a liquid into components
WO2014022275A1 (en) 2012-08-01 2014-02-06 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
EP2906269B1 (en) 2012-10-11 2018-01-03 Magnolia Medical Technologies, Inc. System for delivering a fluid to a patient with reduced contamination
CN104955392B (zh) 2012-11-30 2018-11-02 木兰医药技术股份有限公司 用于体液取样的基于注射器的转移机构
IL303591A (en) 2012-12-04 2023-08-01 Magnolia Medical Technologies Inc Sterile device and methods for collecting body fluids
US10772548B2 (en) 2012-12-04 2020-09-15 Magnolia Medical Technologies, Inc. Sterile bodily-fluid collection device and methods
US10603665B2 (en) 2013-01-29 2020-03-31 Endocellutions, Inc. Cell concentration devices and methods that include an insert defining a lumen and a cannula assembly
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
US9427503B2 (en) * 2013-03-15 2016-08-30 Corvivo Inc. Cardiotomy suction tube system with multiple tips
JP2016509863A (ja) * 2013-03-15 2016-04-04 ラーソン、マルクス カーレ、トールレイフLARSSON, Marcus Kare, Torleif 細胞、臍帯血収集のための方法及び装置、並びに細胞の単離のための方法及び装置
ES2424272B1 (es) * 2013-07-23 2014-01-29 Riera Nadeu, S.A. Supercentrífuga con dispositivo no intrusivo de extracción de sólido y procedimiento de extracción del mismo
CN103342748B (zh) * 2013-07-26 2015-04-08 中国人民解放军第三军医大学第一附属医院 天然软骨基质主要成分-ⅱ型胶原蛋白提取专用装置
CN110064527B (zh) 2014-01-31 2021-12-14 帝斯曼知识产权资产管理有限公司 脂肪组织离心装置和使用方法
WO2015160320A1 (en) * 2014-04-15 2015-10-22 Promedart Biyoteknoloji Ve Ozel Saglik Hizmetleri Sanayi Ticaret Limited Sirketi A separation system
US10906049B2 (en) 2014-06-04 2021-02-02 Biosafe S.A. System for multi-processing and separation of biological fluids
PL3215601T3 (pl) 2014-11-05 2020-11-02 Juno Therapeutics, Inc. Sposoby transdukcji i przetwarzania komórek
WO2016081737A1 (en) * 2014-11-19 2016-05-26 The Regents Of The University Of Colorado, A Body Corporate Apparatus, method, and system for filter based cell capture and labeling with configurable laydown area
EP3233148B1 (en) * 2014-12-19 2019-04-17 Biosafe S.A. Sequential processing of biological fluids
CN104474598B (zh) * 2015-01-05 2016-06-08 浙江保尔曼生物科技有限公司 血浆分离装置
MX2017013479A (es) 2015-05-07 2017-12-07 Biosafe Sa Dispositivo, sistema y metodo para el procesamiento continuo y separacion de fluidos biologicos en componentes.
EP4331643A3 (en) 2015-06-12 2024-04-17 Magnolia Medical Technologies, Inc. Devices and methods for syringe-based fluid transfer for bodily-fluid sampling
US10010282B2 (en) 2015-07-24 2018-07-03 Kurin, Inc. Blood sample optimization system and blood contaminant sequestration device and method
CN108366904B (zh) 2015-09-03 2020-12-01 木兰医药技术股份有限公司 用于维护样本容器的无菌性的设备和方法
CN110088133B (zh) 2016-07-29 2023-12-08 朱诺治疗学股份有限公司 抗独特型抗体及相关方法
CN106110750B (zh) * 2016-08-15 2018-10-16 鲁绍荣 一种高效血液回收机
BR112019004662A2 (pt) 2016-09-12 2019-05-28 Juno Therapeutics Inc conjuntos de sacos de biorreator de perfusão
EP3295972B1 (en) 2016-09-14 2020-11-25 Fenwal, Inc. Cell processing system and method with fill options
US11542473B2 (en) 2016-10-21 2023-01-03 Amniotics Ab Methods and compositions for generating hematopoietic cells
EP3329947B1 (en) 2016-12-01 2021-06-02 Fenwal, Inc. Fill and finish systems and methods
BR112019011207A2 (pt) 2016-12-05 2019-10-08 Juno Therapeutics Inc produção de células modificadas para terapia celular adotiva
JP6309606B1 (ja) 2016-12-21 2018-04-11 三井電気精機株式会社 遠心分離システム
US10827964B2 (en) 2017-02-10 2020-11-10 Kurin, Inc. Blood contaminant sequestration device with one-way air valve and air-permeable blood barrier with closure mechanism
US20200191774A1 (en) 2017-02-27 2020-06-18 Juno Therapeutics, Inc. Compositions, articles of manufacture and methods related to dosing in cell therapy
JP7248324B2 (ja) * 2017-05-12 2023-03-29 サイノジー プロダクツ プロプライエタリー リミテッド コンパクトな逆流遠心分離システムおよびそれに用いる分離チャンバ
US10449555B2 (en) * 2017-05-16 2019-10-22 Robert Bret Carr Centrifugal separator with annular piston for solids extrusion
US10987672B2 (en) * 2017-06-08 2021-04-27 Emcyte Corp. Dual piston centrifuge tube
BR112020001719A2 (pt) 2017-07-29 2020-07-21 Juno Therapeutics Inc reagentes para expansão de células que expressam receptores recombinantes
GB201713252D0 (en) * 2017-08-18 2017-10-04 Biosafe Sa Piston movement
GB201713981D0 (en) * 2017-08-31 2017-10-18 Biosafe Sa Centrifugal separation chamber
WO2019051335A1 (en) 2017-09-07 2019-03-14 Juno Therapeutics, Inc. METHODS OF IDENTIFYING CELLULAR CHARACTERISTICS RELATED TO RESPONSES ASSOCIATED WITH CELL THERAPY
CN116250868A (zh) 2017-09-12 2023-06-13 木兰医药技术股份有限公司 流体控制装置及其使用方法
US20210254000A1 (en) 2017-11-01 2021-08-19 Juno Therapeutics, Inc. Process for producing a t cell composition
BR112020008340A2 (pt) 2017-11-01 2020-11-17 Juno Therapeutics Inc processo para gerar composições terapêuticas de células modificadas
WO2019094835A1 (en) 2017-11-10 2019-05-16 Juno Therapeutics, Inc. Closed-system cryogenic vessels
CA3087992A1 (en) 2017-12-07 2019-06-13 Magnolia Medical Technologies, Inc. Fluid control devices and methods of using the same
GB201720405D0 (en) * 2017-12-07 2018-01-24 Biosafe Sa A bioprocessing system
BR112020011215A2 (pt) 2017-12-08 2020-11-17 Juno Therapeutics Inc processo para a produção de uma composição de células t modificadas
WO2019113559A2 (en) 2017-12-08 2019-06-13 Juno Therapeutics, Inc. Phenotypic markers for cell therapy and related methods
MA51105A (fr) 2017-12-08 2020-10-14 Juno Therapeutics Inc Formulation de milieux sans sérum pour la culture de cellules et ses procédés d'utilisation
JP6425793B2 (ja) * 2017-12-12 2018-11-21 三井電気精機株式会社 遠心分離装置
US11191880B2 (en) * 2018-05-16 2021-12-07 Fenwal, Inc. Fill and finish systems and methods for small volume processing
US11911553B2 (en) * 2018-07-06 2024-02-27 Fenwal, Inc. Systems and methods for concentrating cells with a syringe and a centrifuge
SG11202101130VA (en) 2018-08-09 2021-03-30 Juno Therapeutics Inc Methods for assessing integrated nucleic acids
KR20210057730A (ko) 2018-08-09 2021-05-21 주노 쎄러퓨티크스 인코퍼레이티드 조작 세포 및 이의 조성물 생성 방법
US20220050114A1 (en) 2018-09-11 2022-02-17 Juno Therapeutics, Inc. Methods for mass spectrometry analysis of engineered cell compositions
CN109321458B (zh) * 2018-10-17 2023-03-24 深圳市深研生物科技有限公司 一种制备细胞的方法
CN109225673B (zh) * 2018-10-24 2024-05-31 上海瑛泰医疗器械股份有限公司 一种血液离心分离机
AU2019370705A1 (en) 2018-10-31 2021-05-27 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
AU2019372331A1 (en) 2018-11-01 2021-05-27 Juno Therapeutics, Inc. Methods for treatment using chimeric antigen receptors specific for B-cell maturation antigen
WO2020097132A1 (en) 2018-11-06 2020-05-14 Juno Therapeutics, Inc. Process for producing genetically engineered t cells
MX2021005734A (es) 2018-11-16 2021-09-10 Juno Therapeutics Inc Metodos de dosificacion de celulas t modificadas para el tratamiento de malignidades de celulas b.
FI3886894T3 (fi) 2018-11-30 2024-05-24 Juno Therapeutics Inc Menetelmiä annosteluun ja b-solumaligniteettien hoitoon adoptiivisessa soluterapiassa
CN113710256A (zh) 2018-11-30 2021-11-26 朱诺治疗学股份有限公司 使用过继细胞疗法的治疗方法
US20210220817A1 (en) * 2018-12-08 2021-07-22 Min Wei Apparatus For Manufacturing Cell Therapy Product
CA3129065A1 (en) 2019-02-08 2020-08-13 Magnolia Medical Technologies, Inc. Devices and methods for bodily fluid collection and distribution
US11857321B2 (en) 2019-03-11 2024-01-02 Magnolia Medical Technologies, Inc. Fluid control devices and methods of using the same
JP2022537700A (ja) 2019-06-12 2022-08-29 ジュノー セラピューティクス インコーポレイテッド 細胞媒介細胞傷害性療法と生存促進性bcl2ファミリータンパク質の阻害剤との併用療法
CN110456033A (zh) * 2019-07-03 2019-11-15 深圳市深研生物科技有限公司 用于调整含有细胞的液体样品的密度和或体积的系统
US11478755B2 (en) 2019-08-15 2022-10-25 Fenwal, Inc. Small volume processing systems and methods
WO2021035194A1 (en) 2019-08-22 2021-02-25 Juno Therapeutics, Inc. Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
CN114600172A (zh) 2019-08-30 2022-06-07 朱诺治疗学股份有限公司 用于将细胞分类的机器学习方法
EP4234019A3 (en) 2019-10-18 2023-09-13 Amniotics AB Processes and apparatuses for obtaining amniotic mesenchymal stem cells from amniotic fluid and cells derived thereof
US11559770B2 (en) 2019-10-24 2023-01-24 Fenwal, Inc. Small volume processing systems and methods with capacitive sensing
CA3159380A1 (en) 2019-10-30 2021-05-06 Juno Therapeutics Gmbh Cell selection and/or stimulation devices and methods of use
CN115087868A (zh) 2019-11-05 2022-09-20 朱诺治疗学股份有限公司 确定治疗性t细胞组合物的属性的方法
AU2020395318A1 (en) 2019-12-06 2022-06-09 Juno Therapeutics, Inc. Methods related to toxicity and response associated with cell therapy for treating B cell malignancies
US20230028050A1 (en) 2019-12-06 2023-01-26 Juno Therapeutics, Inc. Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
EP4069742A1 (en) 2019-12-06 2022-10-12 Juno Therapeutics, Inc. Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
KR20220145341A (ko) 2020-01-24 2022-10-28 주노 쎄러퓨티크스 인코퍼레이티드 입양 세포 요법에서 여포성 림프종 및 변연부 림프종의 투여 및 치료 방법
AU2021214142A1 (en) 2020-01-28 2022-09-08 Juno Therapeutics, Inc. Methods for T cell transduction
BR112022015236A2 (pt) 2020-02-12 2022-09-20 Juno Therapeutics Inc Composições de células t do receptor de antígeno quimérico direcionado a cd19 e métodos e usos das mesmas
CN115361955A (zh) 2020-02-12 2022-11-18 朱诺治疗学股份有限公司 针对bcma的嵌合抗原受体t细胞组合物及其方法和用途
BR112022020333A2 (pt) 2020-04-10 2022-11-22 Juno Therapeutics Inc Métodos e usos relacionados à terapia celular projetada com um receptor de antígeno quimérico que alveja o antígeno de maturação de células b
EP4150057A2 (en) 2020-05-13 2023-03-22 Juno Therapeutics, Inc. Process for producing donor-batched cells expressing a recombinant receptor
CN115803824A (zh) 2020-05-13 2023-03-14 朱诺治疗学股份有限公司 鉴定与临床反应相关的特征的方法及其用途
KR20230095918A (ko) 2020-08-05 2023-06-29 주노 쎄러퓨티크스 인코퍼레이티드 Ror1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법
WO2022133030A1 (en) 2020-12-16 2022-06-23 Juno Therapeutics, Inc. Combination therapy of a cell therapy and a bcl2 inhibitor
EP4314280A1 (en) 2021-03-22 2024-02-07 Juno Therapeutics, Inc. Method to assess potency of viral vector particles
CN117321417A (zh) 2021-03-22 2023-12-29 朱诺治疗学股份有限公司 确定治疗性细胞组合物的效力的方法
WO2022212400A1 (en) 2021-03-29 2022-10-06 Juno Therapeutics, Inc. Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
CN113318287A (zh) * 2021-05-31 2021-08-31 衷博瑞佳生物技术(上海)有限公司 一种带内核的活塞式生物液体分离杯及其分离方法
GB2605850B (en) 2021-07-06 2023-04-26 Cellularorigins Ltd Bioprocessing system
CN113943651B (zh) * 2021-11-17 2023-08-18 北京集美生物科技有限公司 一种干细胞提取离心抽取工艺
WO2023230548A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Method for predicting response to a t cell therapy
WO2023230581A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Methods of manufacturing t cell therapies
WO2023250400A1 (en) 2022-06-22 2023-12-28 Juno Therapeutics, Inc. Treatment methods for second line therapy of cd19-targeted car t cells
WO2024032582A1 (en) * 2022-08-09 2024-02-15 Sino-Biocan (Shanghai) Biotech Ltd. Managing peripheral blood cells
WO2024124132A1 (en) 2022-12-09 2024-06-13 Juno Therapeutics, Inc. Machine learning methods for predicting cell phenotype using holographic imaging
US20240285762A1 (en) 2023-02-28 2024-08-29 Juno Therapeutics, Inc. Cell therapy for treating systemic autoimmune diseases
WO2024208455A1 (en) 2023-04-05 2024-10-10 Paolo Gobbi Frattini S.R.L. Method for the preparation of an adipose tissue graft
WO2024220588A1 (en) 2023-04-18 2024-10-24 Juno Therapeutics, Inc. Cytotoxicity assay for assessing potency of therapeutic cell compositions
WO2024226858A1 (en) 2023-04-26 2024-10-31 Juno Therapeutics, Inc. Methods for viral vector manufacturing

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3737096A (en) * 1971-12-23 1973-06-05 Ibm Blood processing control apparatus
JPS59500340A (ja) * 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4946434A (en) * 1986-07-22 1990-08-07 Haemonetics Corporation Disposable manifold and valve
US5641622A (en) 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
JP2528058B2 (ja) * 1992-05-28 1996-08-28 川澄化学工業株式会社 血液成分分離装置
JP3184052B2 (ja) * 1994-08-17 2001-07-09 川澄化学工業株式会社 血液成分分離装置
WO1997015399A1 (en) * 1996-04-24 1997-05-01 Claude Fell Cell separation system for biological fluids like blood
US6098646A (en) * 1997-02-19 2000-08-08 Ecolab Inc. Dispensing system with multi-port valve for distributing use dilution to a plurality of utilization points and position sensor for use thereon

Also Published As

Publication number Publication date
WO2000038762A1 (en) 2000-07-06
CN1331610A (zh) 2002-01-16
AU1675600A (en) 2000-07-31
JP2002533171A (ja) 2002-10-08
ES2224726T3 (es) 2005-03-01
EP1144026B1 (en) 2004-07-28
EP1144026A1 (en) 2001-10-17
DE69919029T2 (de) 2005-09-08
US6733433B1 (en) 2004-05-11
ATE271890T1 (de) 2004-08-15
HK1041454B (zh) 2004-12-31
DE69919029D1 (de) 2004-09-02
CN1182882C (zh) 2005-01-05
JP4514338B2 (ja) 2010-07-28
HK1041454A1 (en) 2002-07-12

Similar Documents

Publication Publication Date Title
PT1144026E (pt) Sistema para separacao sanguinea util, em particular, para concentracoes de celulas estaminais hematopoieticas
US20190204209A1 (en) Generating a Fluid Stream in a Microfluidic Device
AU6467796A (en) Cell separation system for biological fluids like blood
ATE209063T1 (de) Blutsammelsystem
WO2002029380A3 (en) Air samplers
KR101342446B1 (ko) 연속적으로 조절되는 정밀 압력 유체 전달 시스템
DE50111594D1 (de) Vorrichtung und verfahren zur separation von ungelösten bestandteilen aus biologischen flüssigkeiten
CN104969076A (zh) 生物化学用滤芯、生物化学用滤芯和滤芯座的组
GB916373A (en) Method and apparatus for use in determining the effect of substances on animal or plant cells
CN108339578A (zh) 液滴进样器以及使用其的液滴进样方法
EP0246979B1 (fr) Dispositif permettant de conserver la stérilité d'un milieu de culture en enceinte pendant le prélèvement d'échantillons
US4680266A (en) Cell culture chamber with means for automatic replenishment of nutrient
ATE485088T1 (de) Vorrichtung zum trennen von fluidgemischen
GB852615A (en) Apparatus and method for biological assays
Gunsalus et al. A procedure for anaerobic column chromatography employing an anaerobic Freter-type chamber
CN102747136A (zh) 生物流体中细菌的检测
PT1049499E (pt) Aparelho para uso na extraccao de elementos especialmente anticorpos exogenos presentes no sangue ou no plasma
BR9909813A (pt) Aparelho e sistema de enchimento e processo para introduzir em um recipiente, uma suspensão ou solução de uma substância
Rose On the osmotic behaviour of Saccharomyces cerevisiae as affected by biotin deficiency
BRPI0416671A (pt) acoplador de sistema de fluido
Ryu et al. A comparison of enzyme preparations to liberate folic acid for the microbiological assay of feed ingredients
US20140374360A1 (en) Method for separating suspension or colloid components and a device for separating suspension or colloid components
KR980003582A (ko) 유성 세포 측정방법(Flow Cytometry)을 이용한 세균내의 단백질 측정방법
Parikh et al. Interaction of meningopneumonitis virus with white blood cells: II. Antigenic subunits of meningopneumonitis virus
Lees et al. Effect of flow rate and freezing on cyanocobalamin recovery using a commercial solid phase extraction cartridge