PL3494960T3 - Stabilized compositions of alkylating agents and methods of using same - Google Patents

Stabilized compositions of alkylating agents and methods of using same

Info

Publication number
PL3494960T3
PL3494960T3 PL18214529T PL18214529T PL3494960T3 PL 3494960 T3 PL3494960 T3 PL 3494960T3 PL 18214529 T PL18214529 T PL 18214529T PL 18214529 T PL18214529 T PL 18214529T PL 3494960 T3 PL3494960 T3 PL 3494960T3
Authority
PL
Poland
Prior art keywords
methods
same
alkylating agents
stabilized compositions
stabilized
Prior art date
Application number
PL18214529T
Other languages
Polish (pl)
Inventor
Robert Alonso
Barry R. Walker
Peter A. Crooks
Original Assignee
Helsinn Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinn Healthcare Sa filed Critical Helsinn Healthcare Sa
Publication of PL3494960T3 publication Critical patent/PL3494960T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL18214529T 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same PL3494960T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3984008P 2008-03-27 2008-03-27
EP18214529.2A EP3494960B1 (en) 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same
PCT/US2009/036737 WO2009120493A2 (en) 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same
EP09724939.5A EP2273876B1 (en) 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same

Publications (1)

Publication Number Publication Date
PL3494960T3 true PL3494960T3 (en) 2021-05-17

Family

ID=41114573

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09724939T PL2273876T3 (en) 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same
PL18214529T PL3494960T3 (en) 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL09724939T PL2273876T3 (en) 2008-03-27 2009-03-11 Stabilized compositions of alkylating agents and methods of using same

Country Status (14)

Country Link
US (2) US8501817B2 (en)
EP (2) EP3494960B1 (en)
CN (2) CN107149591A (en)
CY (2) CY1121777T1 (en)
DK (1) DK3494960T3 (en)
ES (2) ES2727523T3 (en)
HR (2) HRP20190551T1 (en)
HU (2) HUE043767T2 (en)
LT (2) LT3494960T (en)
PL (2) PL2273876T3 (en)
PT (2) PT3494960T (en)
SI (2) SI3494960T1 (en)
TR (1) TR201907794T4 (en)
WO (1) WO2009120493A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7872050B2 (en) 2005-03-14 2011-01-18 Yaupon Therapeutics Inc. Stabilized compositions of volatile alkylating agents and methods of using thereof
US8501818B2 (en) * 2005-03-14 2013-08-06 Ceptaris Therapeutics, Inc. Stabilized compositions of alkylating agents and methods of using same
US20110039943A1 (en) * 2005-03-14 2011-02-17 Robert Alonso Methods for treating skin disorders with topical nitrogen mustard compositions
PL2273876T3 (en) 2008-03-27 2019-09-30 Helsinn Healthcare Sa Stabilized compositions of alkylating agents and methods of using same
US20180125797A1 (en) * 2016-11-07 2018-05-10 Actelion Pharmaceuticals Ltd Methods for treating skin disorders with a topical composition of bis-(2-chloroethyl)methylamine

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US4206222A (en) * 1977-06-23 1980-06-03 Societe Civile Particuliere De Brevets Suffren Method for preparing a substance having properties against collagen diseases and products obtained
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US4888354A (en) * 1987-12-21 1989-12-19 Theratech, Inc. Skin penetration enhancement using free base and acid addition salt combinations of active agents
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US4949641A (en) 1990-03-05 1990-08-21 The United States Of America As Represented By The Secretary Of The Army Method of safely detoxifying mustard gases
US6764681B2 (en) * 1991-10-07 2004-07-20 Biogen, Inc. Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
US5820872A (en) 1992-11-18 1998-10-13 Yale University Methods and compositions for improving the effectiveness of X-irradiation therapy for the treatment of an internal solid tumor
WO1995003028A1 (en) * 1993-07-23 1995-02-02 Morris Herstein Cosmetic, skin-renewal stimulating composition with long-term irritation control
FR2728166A1 (en) * 1994-12-19 1996-06-21 Oreal TOPICAL COMPOSITION CONTAINING AN ANTAGONIST OF SUBSTANCE P
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US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
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BR9710241A (en) * 1996-07-11 1999-08-10 Farmarc Nederland Bv Inclusion compromise that contains indole-selective serotonin agonist
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WO1999042578A2 (en) * 1998-01-30 1999-08-26 Cold Spring Harbor Laboratory Modulation of cell proliferation, methods and reagents
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US20110039943A1 (en) * 2005-03-14 2011-02-17 Robert Alonso Methods for treating skin disorders with topical nitrogen mustard compositions
US7872050B2 (en) 2005-03-14 2011-01-18 Yaupon Therapeutics Inc. Stabilized compositions of volatile alkylating agents and methods of using thereof
US20060281720A1 (en) * 2005-06-08 2006-12-14 Loria Roger M 5-Androstenediol As An Inhibitor of Gliomas
PL2273876T3 (en) * 2008-03-27 2019-09-30 Helsinn Healthcare Sa Stabilized compositions of alkylating agents and methods of using same

Also Published As

Publication number Publication date
US8501817B2 (en) 2013-08-06
CY1121777T1 (en) 2020-07-31
LT3494960T (en) 2021-02-25
CY1123974T1 (en) 2022-05-27
LT2273876T (en) 2019-05-27
PL2273876T3 (en) 2019-09-30
HRP20190551T1 (en) 2019-05-03
CN107149591A (en) 2017-09-12
US20100029783A9 (en) 2010-02-04
SI3494960T1 (en) 2021-04-30
EP2273876A2 (en) 2011-01-19
CN102036557A (en) 2011-04-27
WO2009120493A2 (en) 2009-10-01
HUE053482T2 (en) 2021-06-28
ES2848841T3 (en) 2021-08-12
EP3494960B1 (en) 2020-11-25
EP2273876A4 (en) 2013-10-23
TR201907794T4 (en) 2019-06-21
SI2273876T1 (en) 2019-09-30
HRP20210283T1 (en) 2021-04-02
US20090247645A1 (en) 2009-10-01
EP2273876B1 (en) 2019-03-06
EP3494960A1 (en) 2019-06-12
PT2273876T (en) 2019-06-04
DK3494960T3 (en) 2021-01-25
WO2009120493A3 (en) 2010-03-04
ES2727523T3 (en) 2019-10-16
PT3494960T (en) 2021-02-09
HUE043767T2 (en) 2019-09-30
US20140142193A1 (en) 2014-05-22

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