PL212223A1 - METHOD OF MAKING GUANIDINE DERIVATIVES - Google Patents

METHOD OF MAKING GUANIDINE DERIVATIVES

Info

Publication number
PL212223A1
PL212223A1 PL21222378A PL21222378A PL212223A1 PL 212223 A1 PL212223 A1 PL 212223A1 PL 21222378 A PL21222378 A PL 21222378A PL 21222378 A PL21222378 A PL 21222378A PL 212223 A1 PL212223 A1 PL 212223A1
Authority
PL
Poland
Prior art keywords
guanidine derivatives
making
making guanidine
derivatives
guanidine
Prior art date
Application number
PL21222378A
Other languages
Polish (pl)
Other versions
PL115042B1 (en
Inventor
Pierre Baudet
Jean-Paul Ricard
Adrian Schulthess
Original Assignee
Om Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1612677A external-priority patent/CH626353A5/en
Priority claimed from CH1247778A external-priority patent/CH636348A5/en
Application filed by Om Lab Sa filed Critical Om Lab Sa
Publication of PL212223A1 publication Critical patent/PL212223A1/en
Publication of PL115042B1 publication Critical patent/PL115042B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43Y being a hetero atom
    • C07C323/44X or Y being nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00Thiocarbonic acids; Halides, esters or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/20Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carbonic acid, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL1978212223A 1977-12-28 1978-12-28 Method of manufacture of therapeutically active derivative of guanidine PL115042B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1612677A CH626353A5 (en) 1977-12-28 1977-12-28 Process for the preparation of a guanidine
CH1247778A CH636348A5 (en) 1978-12-07 1978-12-07 Process for the preparation of guanidine derivatives

Publications (2)

Publication Number Publication Date
PL212223A1 true PL212223A1 (en) 1979-08-27
PL115042B1 PL115042B1 (en) 1981-03-31

Family

ID=25710349

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1978212223A PL115042B1 (en) 1977-12-28 1978-12-28 Method of manufacture of therapeutically active derivative of guanidine

Country Status (12)

Country Link
JP (2) JPS5827792B2 (en)
CS (1) CS208770B2 (en)
DE (1) DE2855836A1 (en)
ES (1) ES476707A1 (en)
FI (1) FI74954C (en)
IL (1) IL56265A (en)
IT (1) IT1102776B (en)
NL (1) NL184832C (en)
PL (1) PL115042B1 (en)
RO (1) RO76087A (en)
SU (1) SU1077570A3 (en)
YU (1) YU41138B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
GR65283B (en) * 1977-12-30 1980-08-01 Crc Ricerca Chim Method for the alkyliosis of 4(5)-merka ptomethyl-imidazoles with aziridin derivatives
YU40332B (en) * 1978-04-26 1985-12-31 Lek Tovarna Farmacevtskih Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine
LU81178A1 (en) * 1978-05-12 1979-09-10 Crc Ricerca Chim NEW THIOLD DERIVATIVES OF IMIDAZOLE
US4222845A (en) * 1978-12-13 1980-09-16 Gulf Oil Corporation Integrated coal liquefaction-gasification-naphtha reforming process
WO1980001694A1 (en) * 1979-02-14 1980-08-21 Rech Syntheses Organ Imino-alkyl and amino-nitryl cyano-guanidinze
CH642068A5 (en) * 1979-03-14 1984-03-30 Rech Syntheses Organ THERAPEUTICALLY ACTIVE CYANO-UREA AND CYANO-THIOURAE.
PT72320B (en) 1980-01-08 1982-07-23 Glaxo Group Ltd Process for preparation of a furan derivative
YU41689B (en) * 1980-01-14 1987-12-31 Lek Tovarna Farmacevtskih Process for preparing imidazole derivatives
DE3014353A1 (en) * 1980-04-15 1982-01-21 Bayer Ag, 5090 Leverkusen TRISUBSTITUTED CYANGUANIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS FUNGICIDES
JPS5888366A (en) * 1981-11-19 1983-05-26 Fujimoto Seiyaku Kk Preparation of guanidine derivative
JPS59130273A (en) * 1983-01-14 1984-07-26 Tokawa Tetsuo Preparation of imidazole compound
JPS6170789U (en) * 1984-10-16 1986-05-14
GB8502446D0 (en) * 1985-01-31 1985-03-06 Smith Kline French Lab Preparing aziridine derivative
SI8710091A8 (en) * 1987-01-23 1996-06-30 Lek Tovarna Farmacevtskih Process for obtaining crystalline cimetadine (n-cyano-n'-methyl-n"- (2/(5-methyl-1h-imidazole-4-yl)methylthio/ethyl)-guanidine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE36050B1 (en) * 1971-03-09 1976-08-04 Smith Kline French Lab Ureas thioureas and guanidines
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
JPS5817511B2 (en) * 1975-10-03 1983-04-07 積水化学工業株式会社 Setuchiyakuzaisoseibutsu
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
JPS5440547A (en) * 1977-09-07 1979-03-30 Seikosha Kk Device for adjusting output frequency of frequency divider
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
JPS5742068A (en) * 1980-08-27 1982-03-09 Ricoh Co Ltd Solvent recovering device for wet type electronic copying machine
JPS6011994B2 (en) * 1981-08-10 1985-03-29 池田 博美 Liquid fuel for gasoline engines
JPS5888366A (en) * 1981-11-19 1983-05-26 Fujimoto Seiyaku Kk Preparation of guanidine derivative

Also Published As

Publication number Publication date
DE2855836A1 (en) 1979-07-12
IT1102776B (en) 1985-10-07
YU308478A (en) 1983-01-21
JPS54130566A (en) 1979-10-09
JPS6140667B2 (en) 1986-09-10
CS208770B2 (en) 1981-09-15
PL115042B1 (en) 1981-03-31
SU1077570A3 (en) 1984-02-29
FI783990A (en) 1979-06-29
JPS5962572A (en) 1984-04-10
NL7812600A (en) 1979-07-02
YU41138B (en) 1986-12-31
FI74954C (en) 1988-04-11
JPS5827792B2 (en) 1983-06-11
ES476707A1 (en) 1979-06-01
NL184832C (en) 1989-11-16
RO76087A (en) 1981-02-28
IT7831392A0 (en) 1978-12-28
DE2855836C2 (en) 1989-09-28
IL56265A0 (en) 1979-03-12
IL56265A (en) 1982-08-31
FI74954B (en) 1987-12-31

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