OA08871A - New thiazole derivatives active on the cholinergic system, process for obtaining them and pharmaceutical compositions containing them. - Google Patents

New thiazole derivatives active on the cholinergic system, process for obtaining them and pharmaceutical compositions containing them.

Info

Publication number: OA08871A
Authority: OA; OAPI
Prior art keywords: obtaining; pharmaceutical compositions; compositions containing; thiazole derivatives; cholinergic system
Prior art date: 1987-03-12

Application number

OA59299A

Other languages

French (fr)

Inventor

Biziere Kathleen

Olliero Dominique

Worms Paul

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-12

Filing date

1988-03-11

Publication date

1989-10-31

1988-03-11 Application filed by Sanofi Sa filed Critical Sanofi Sa

1989-10-31 Publication of OA08871A publication Critical patent/OA08871A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/84—Naphthothiazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)

OA59299A 1987-03-12 1988-03-11 New thiazole derivatives active on the cholinergic system, process for obtaining them and pharmaceutical compositions containing them. OA08871A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8703398A FR2612187B1 (en)	1987-03-12	1987-03-12	THIAZOLE DERIVATIVES ACTIVE IN THE CHOLINERGIC SYSTEM, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (1)

Publication Number	Publication Date
OA08871A true OA08871A (en)	1989-10-31

Family

ID=9348897

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA59299A OA08871A (en)	1987-03-12	1988-03-11	New thiazole derivatives active on the cholinergic system, process for obtaining them and pharmaceutical compositions containing them.

Country Status (27)

Country	Link
EP (1)	EP0283390B1 (en)
JP (1)	JPS63243080A (en)
KR (1)	KR880011135A (en)
AR (1)	AR243515A1 (en)
AT (1)	ATE86249T1 (en)
AU (1)	AU612350B2 (en)
DD (1)	DD274028A5 (en)
DE (1)	DE3878708T2 (en)
DK (1)	DK170162B1 (en)
ES (1)	ES2053778T3 (en)
FI (1)	FI881152A (en)
FR (1)	FR2612187B1 (en)
HU (1)	HU198916B (en)
IE (1)	IE60173B1 (en)
IL (1)	IL85704A (en)
MA (1)	MA21207A1 (en)
MY (1)	MY103233A (en)
NO (1)	NO170081C (en)
NZ (1)	NZ223845A (en)
OA (1)	OA08871A (en)
PH (1)	PH25389A (en)
PL (1)	PL151889B1 (en)
PT (1)	PT86952B (en)
SU (1)	SU1604157A3 (en)
TN (1)	TNSN88020A1 (en)
YU (1)	YU49688A (en)
ZA (1)	ZA881764B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6440474A (en) *	1987-08-04	1989-02-10	Hisamitsu Pharmaceutical Co	Novel 2-substituted aminothiazole derivative
JPH0753666B2 (en) *	1987-09-14	1995-06-07	久光製薬株式会社	Anti-inflammatory agent consisting of substituted diphenylthiazole derivative
FR2656610B1 (en) *	1989-12-29	1992-05-07	Sanofi Sa	DERIVATIVES OF 2-AMINO PHENYL-4 THIAZOLE, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION.
EP0535227A4 (en) *	1990-05-29	1993-08-18	Nippon Soda Co., Ltd.	N-substituted heterocyclic amidine derivative
WO1992021666A1 (en) *	1991-05-31	1992-12-10	Laboratoires Upsa	Angiotensin ii receptor antagonist thiazole devivatives
FR2677021B1 (en) *	1991-05-31	1993-10-01	Upsa Laboratoires	NOVEL THIAZOLE DERIVATIVES ANTAGONISTS OF ANGIOTENSIN II RECEPTORS; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2692893B1 (en) *	1992-06-24	1994-09-02	Sanofi Elf	Branched alkylamino thiazole derivatives, processes for their preparation and pharmaceutical compositions containing them.
WO1994020476A1 (en) *	1993-03-02	1994-09-15	Fujisawa Pharmaceutical Co., Ltd.	Novel heterocyclic compound
FR2714059B1 (en) *	1993-12-21	1996-03-08	Sanofi Elf	Branched amino derivatives of thiazole, processes for their preparation and pharmaceutical compositions containing them.
FR2735777B1 (en) *	1995-06-21	1997-09-12	Sanofi Sa	4-PHENYLAMINOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2754258B1 (en) *	1996-10-08	1998-12-31	Sanofi Sa	AMINOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
GB9705428D0 (en) *	1997-03-15	1997-04-30	Knoll Ag	Therapeutic agents
AU768751B2 (en) *	1998-06-18	2004-01-08	Bristol-Myers Squibb Company	Carbon substituted aminothiazole inhibitors of cyclin dependent kinases
EP1816127A1 (en)	1999-04-22	2007-08-08	H. Lundbeck A/S	Triazine derivatives for use as selective npy (y5) antagonists
US6218408B1 (en)	1999-06-30	2001-04-17	Synaptic Pharmaceutical Corporation	Selective NPY (Y5) antagonists (bicyclics)
US6340683B1 (en)	1999-04-22	2002-01-22	Synaptic Pharmaceutical Corporation	Selective NPY (Y5) antagonists (triazines)
US6989379B1 (en)	1999-04-22	2006-01-24	H. Lundbick A/S	Selective NPY (Y5) antagonists
US6225330B1 (en)	1999-06-30	2001-05-01	Synaptic Pharmaceutical Corporation	Selective NPY (Y5) antagonists (tricyclics)
US7273880B2 (en)	1999-06-30	2007-09-25	H. Lunbeck A/S	Selective NPY (Y5) antagonists
US6222040B1 (en)	1999-06-30	2001-04-24	Synaptic Pharmaceutical Corporation	Selective NPY (Y5) antagonists (tricyclics)
US6214853B1 (en)	1999-06-30	2001-04-10	Synaptic Pharmaceutical Corporation	Selective NPY (Y5) antagonists (bicyclics)
WO2002083863A2 (en)	2001-04-17	2002-10-24	Sepracor, Inc.	Thiazole and other heterocyclic ligands and use thereof
US7485655B2 (en) *	2002-01-16	2009-02-03	University Of Virginia Patent Foundation	2-Aminothiazole allosteric enhancers of A1 adenosine receptors
DE10251513A1 (en) *	2002-11-04	2004-05-19	Basf Ag	Compounds with 5-membered heterocycle linked by amino- or phosphino-methyl to a benzene ring with an ortho-hydroxy, alkoxy, thiol or amino group, used as multidentate ligands in olefin polymerization catalysts
JP2007261945A (en) *	2004-04-07	2007-10-11	Taisho Pharmaceut Co Ltd	Thiazole derivative
US7880008B2 (en) *	2005-05-31	2011-02-01	Vertex Pharmaceuticals Incorporated	Heterocycles useful as modulators of ion channels
KR20110137941A (en) *	2010-06-18	2011-12-26	(주) 에빅스젠	Novel thiourea or urea derivative, process for preparing the same and pharmaceutical composition for preventing or treating aids comprising the same
RU2456284C1 (en) *	2011-04-12	2012-07-20	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Уральский федеральный университет имени первого Президента России Б.Н. Ельцина"	2-aminopropylmorpholino-5-aryl-6h-1,3,4-thiadiazines, dihydrobromides and 2-aminopropylmorpholino-4-arylthiazoles, hydrobromides showing antiaggregant action
IL308138A (en)	2014-11-10	2023-12-01	Evrys Bio Llc	Anti-hcmv compositions and methods
CN115160207B (en) *	2022-04-21	2023-09-26	烟台大学	Benzoyl thiourea compound, preparation method thereof and application of red tide algae algicide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2975182A (en) *	1959-11-16	1961-03-14	Paul A J Janssen	1-(aroylalkyl)-4-(heterocyclyl) piperazines
FR2092714B1 (en) *	1970-06-11	1974-03-22	Melle Bezons
CH583232A5 (en) *	1973-02-02	1976-12-31	Wander Ag Dr A
DE3135250A1 (en) *	1981-09-05	1983-03-17	Basf Ag, 6700 Ludwigshafen	TRICYCLIC THIAZOLYLOXAMATES, METHOD FOR THE PRODUCTION THEREOF AND THERAPEUTIC AGENTS CONTAINING THEM
US4552886A (en) *	1982-06-07	1985-11-12	Eli Lilly And Company	Fungicidal pyridylmethyl-amines
FR2581063B1 (en) *	1985-04-30	1987-07-17	Chauvin Blache Lab	AMINO-2 THIAZOLES N-SUBSTITUTED, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS
HUT43600A (en) *	1985-06-22	1987-11-30	Sandoz Ag	Process for production of new thiazole derivatives and medical compound containing those

1987
- 1987-03-12 FR FR8703398A patent/FR2612187B1/en not_active Expired
1988
- 1988-03-03 AU AU12662/88A patent/AU612350B2/en not_active Ceased
- 1988-03-08 DD DD88313502A patent/DD274028A5/en not_active IP Right Cessation
- 1988-03-08 MA MA21448A patent/MA21207A1/en unknown
- 1988-03-09 DK DK128688A patent/DK170162B1/en not_active IP Right Cessation
- 1988-03-09 PH PH36616A patent/PH25389A/en unknown
- 1988-03-10 NZ NZ223845A patent/NZ223845A/en unknown
- 1988-03-10 AR AR88310267A patent/AR243515A1/en active
- 1988-03-11 ZA ZA881764A patent/ZA881764B/en unknown
- 1988-03-11 FI FI881152A patent/FI881152A/en not_active Application Discontinuation
- 1988-03-11 IE IE72188A patent/IE60173B1/en not_active IP Right Cessation
- 1988-03-11 SU SU884355377A patent/SU1604157A3/en active
- 1988-03-11 ES ES88400572T patent/ES2053778T3/en not_active Expired - Lifetime
- 1988-03-11 EP EP88400572A patent/EP0283390B1/en not_active Expired - Lifetime
- 1988-03-11 OA OA59299A patent/OA08871A/en unknown
- 1988-03-11 IL IL85704A patent/IL85704A/en unknown
- 1988-03-11 YU YU00496/88A patent/YU49688A/en unknown
- 1988-03-11 AT AT88400572T patent/ATE86249T1/en not_active IP Right Cessation
- 1988-03-11 MY MYPI88000258A patent/MY103233A/en unknown
- 1988-03-11 TN TNTNSN88020A patent/TNSN88020A1/en unknown
- 1988-03-11 DE DE8888400572T patent/DE3878708T2/en not_active Expired - Fee Related
- 1988-03-11 PL PL1988271132A patent/PL151889B1/en unknown
- 1988-03-11 HU HU881190A patent/HU198916B/en not_active IP Right Cessation
- 1988-03-11 NO NO881093A patent/NO170081C/en unknown
- 1988-03-11 PT PT86952A patent/PT86952B/en not_active IP Right Cessation
- 1988-03-12 JP JP63059223A patent/JPS63243080A/en active Pending
- 1988-03-12 KR KR1019880002614A patent/KR880011135A/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2053778T3 (en)	1994-08-01
PT86952B (en)	1992-05-29
PH25389A (en)	1991-06-03
NO170081C (en)	1992-09-09
ZA881764B (en)	1988-08-31
HU198916B (en)	1989-12-28
NO881093D0 (en)	1988-03-11
FI881152A0 (en)	1988-03-11
AU1266288A (en)	1988-09-15
SU1604157A3 (en)	1990-10-30
JPS63243080A (en)	1988-10-07
PL151889B1 (en)	1990-10-31
IE880721L (en)	1988-09-12
AU612350B2 (en)	1991-07-11
FR2612187B1 (en)	1989-07-21
DE3878708D1 (en)	1993-04-08
NO170081B (en)	1992-06-01
TNSN88020A1 (en)	1990-07-10
FR2612187A1 (en)	1988-09-16
PL271132A1 (en)	1988-11-24
MA21207A1 (en)	1988-10-01
NO881093L (en)	1988-09-13
DK128688D0 (en)	1988-03-09
MY103233A (en)	1993-05-29
ATE86249T1 (en)	1993-03-15
HUT47261A (en)	1989-02-28
YU49688A (en)	1989-10-31
EP0283390A2 (en)	1988-09-21
KR880011135A (en)	1988-10-26
PT86952A (en)	1988-04-01
IE60173B1 (en)	1994-06-15
IL85704A (en)	1992-11-15
DE3878708T2 (en)	1993-09-02
NZ223845A (en)	1990-11-27
FI881152A (en)	1988-09-13
EP0283390A3 (en)	1988-09-28
EP0283390B1 (en)	1993-03-03
DD274028A5 (en)	1989-12-06
DK170162B1 (en)	1995-06-06
AR243515A1 (en)	1993-08-31
DK128688A (en)	1988-09-13
IL85704A0 (en)	1988-08-31

Publication	Publication Date	Title
OA08871A (en)	1989-10-31	New thiazole derivatives active on the cholinergic system, process for obtaining them and pharmaceutical compositions containing them.
DZ2300A1 (en)	2002-12-25	Substituted 6,5-heterobicyclic derivatives, process for their preparation and pharmaceutical compositions containing them.
DZ2299A1 (en)	2002-12-25	Substituted 6,6-heterobicyclic derivatives, process for their preparation and pharmaceutical compositions containing them.
DZ2197A1 (en)	2002-12-02	6-Phenylpyridyl-2-amine derivatives, process for their preparation and pharmaceutical compositions containing them.
OA08481A (en)	1988-07-29	Indolizine derivatives, their preparation process and the compositions containing them.
OA08647A (en)	1988-11-30	Imidazole derivatives, processes for their preparation and pharmaceutical composition containing them.
DZ2227A1 (en)	2002-12-25	New indole derivatives, process for their preparation and pharmaceutical formulations containing them.
DZ2666A1 (en)	2003-03-22	Hydroxamic acid derivatives pharmaceutical compositions containing them and process for their preparation.
DZ1957A1 (en)	2002-02-17	New piperidine derivatives, process for their preparation and pharmaceutical compositions containing them.
DZ2581A1 (en)	2003-02-22	Aryloxyarylsulfonylaminohydroxamic acid derivatives process for their preparation and pharmaceutical compositions containing them.
DZ1889A1 (en)	2002-02-17	New quinoline derivatives, process for their preparation and pharmaceutical compositions containing them.
DZ3042A1 (en)	2004-03-27	New isothiazole derivatives, process for their preparation and pharmaceutical compositions containing them.
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DZ2074A1 (en)	2002-07-22	New formulation containing paroxetine, and process for its preparation.
FR2636628B1 (en)	1990-12-28	THIADIAZOLE-1,3,4 DERIVATIVES, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
MC1915A1 (en)	1989-04-06	Processes for the preparation of 2 ', 3'-dideoxynucleosides and pharmaceutical formulations containing them
DZ2550A1 (en)	2003-02-08	Azetidinylpropylpiperidine derivatives process for their preparation and pharmaceutical compositions containing them.
FR2716195B1 (en)	1996-06-21	Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them
OA09190A (en)	1992-06-30	"Processes for the preparation of benzocycloalkenyl dihydroxy alkanoic acid derivatives and medicaments containing them".
DZ2155A1 (en)	2002-10-26	Aazetidines, process for their preparation, and pharmaceutical compositions containing them.
OA09442A (en)	1992-10-15	Thienotriazolo-diazepine derivatives, a process for their preparation and therapeutic compositions containing them.
DE3777122D1 (en)	1992-04-09	ALKANSULFONANILIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
FR2692579B1 (en)	1995-06-02	New picromycin derivatives, their preparation process and their use as medicines.
DE3767894D1 (en)	1991-03-14	1,2-DITHIOL-3-THION DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE PHARMACEUTICAL COMPOSITION CONTAINING THEM.
FR2662692B1 (en)	1995-04-28	HETEROCYCLIC DERIVATIVES WITH ANTICONVULSIVE ACTIVITY, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION.