NO952949D0 - Forlöpere av anti-inflamatoriske 3-acyl-2-oksindol-1-karboksamider - Google Patents

Forlöpere av anti-inflamatoriske 3-acyl-2-oksindol-1-karboksamider

Info

Publication number
NO952949D0
NO952949D0 NO952949A NO952949A NO952949D0 NO 952949 D0 NO952949 D0 NO 952949D0 NO 952949 A NO952949 A NO 952949A NO 952949 A NO952949 A NO 952949A NO 952949 D0 NO952949 D0 NO 952949D0
Authority
NO
Norway
Prior art keywords
oxindole
carboxamides
precursors
acyl
inflammatory
Prior art date
Application number
NO952949A
Other languages
English (en)
Other versions
NO952949L (no
Inventor
Wayne E Barth
Kelvin Cooper
Edward Fox Kleinman
Lawrence Alan Reiter
Ralph P Robinson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO952949L publication Critical patent/NO952949L/no
Publication of NO952949D0 publication Critical patent/NO952949D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO952949A 1993-01-26 1995-07-25 Forlöpere av anti-inflamatoriske 3-acyl-2-oksindol-1-karboksamider NO952949D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/009,188 US5270331A (en) 1993-01-26 1993-01-26 Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
PCT/US1993/009813 WO1994017061A1 (en) 1993-01-26 1993-10-20 Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

Publications (2)

Publication Number Publication Date
NO952949L NO952949L (no) 1995-07-25
NO952949D0 true NO952949D0 (no) 1995-07-25

Family

ID=21736103

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952949A NO952949D0 (no) 1993-01-26 1995-07-25 Forlöpere av anti-inflamatoriske 3-acyl-2-oksindol-1-karboksamider

Country Status (35)

Country Link
US (1) US5270331A (no)
EP (1) EP0681580B1 (no)
JP (1) JP2703825B2 (no)
KR (1) KR0169827B1 (no)
CN (1) CN1052003C (no)
AP (1) AP443A (no)
AT (1) ATE155137T1 (no)
AU (1) AU678187B2 (no)
BR (1) BR9307768A (no)
CA (1) CA2152919C (no)
CZ (1) CZ181995A3 (no)
DE (1) DE69312093T2 (no)
DK (1) DK0681580T3 (no)
EG (1) EG20302A (no)
ES (1) ES2104187T3 (no)
FI (1) FI940365A (no)
GR (1) GR3024591T3 (no)
HR (1) HRP940034B1 (no)
HU (1) HUT69689A (no)
IL (1) IL108384A (no)
MA (1) MA23096A1 (no)
MX (1) MX9400677A (no)
MY (1) MY138629A (no)
NO (1) NO952949D0 (no)
NZ (1) NZ257278A (no)
OA (1) OA10563A (no)
PL (1) PL178857B1 (no)
RU (1) RU2124514C1 (no)
SI (1) SI9300567A (no)
SK (1) SK280929B6 (no)
TW (1) TW330935B (no)
UA (1) UA41348C2 (no)
WO (1) WO1994017061A1 (no)
YU (1) YU48796B (no)
ZA (1) ZA94463B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE145206T1 (de) * 1993-02-09 1996-11-15 Pfizer Oxindol 1-(n-(alkoxycarbonyl)>carboxamide und 1- (n-carboxamido>carboxamide als antiinflammatorische wirkstoffe
WO1997013767A1 (de) * 1995-10-09 1997-04-17 Chemisch Pharmazeutische Forschungsgesellschaft Mbh Heterocyclisch substituierte 1-indolcarboxamide als cyclooxygenase-2 inhibitoren
ATE249828T1 (de) * 1998-03-06 2003-10-15 Astrazeneca Ab Verwendung von isatin- und oxindolderivaten zur herstellung von arzeneimittel für die behandlung von mykobakteriellen erkrankungen
EP0984012A3 (en) * 1998-08-31 2001-01-10 Pfizer Products Inc. Nitric oxide releasing oxindole prodrugs with analgesic and anti-inflammatory properties
AU2002325614A1 (en) * 2001-08-16 2003-03-03 Pharmacon-Forschung Und Beratung Gmbh Compounds containing lactic acid elements, method for the production and use thereof as pharmaceutically active substances
CN101628842A (zh) * 2009-08-27 2010-01-20 中国人民解放军防化指挥工程学院 烷氧羰基甲氧基作为羧基保护基

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
ES2075055T3 (es) * 1988-10-18 1995-10-01 Pfizer Profarmacos de 3-acil-2-oxindol-1-carboxamidas antiinflamatorias.
US5118703A (en) * 1988-10-18 1992-06-02 Pfizer Inc. Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

Also Published As

Publication number Publication date
IL108384A0 (en) 1994-04-12
NZ257278A (en) 1996-09-25
GR3024591T3 (en) 1997-12-31
YU48796B (sh) 2000-03-21
CZ281046B6 (cs) 1996-06-12
ZA94463B (en) 1995-07-24
EG20302A (en) 1998-10-31
CA2152919A1 (en) 1994-08-04
TW330935B (en) 1998-05-01
SK91295A3 (en) 1995-12-06
CN1052003C (zh) 2000-05-03
OA10563A (en) 2002-06-05
BR9307768A (pt) 1995-11-21
ES2104187T3 (es) 1997-10-01
KR960700244A (ko) 1996-01-19
NO952949L (no) 1995-07-25
WO1994017061A1 (en) 1994-08-04
RU2124514C1 (ru) 1999-01-10
DE69312093T2 (de) 1997-10-30
FI940365A (fi) 1994-07-27
AP9300583A0 (en) 1993-10-31
AP443A (en) 1996-01-03
HRP940034A2 (en) 1996-08-31
HUT69689A (en) 1995-09-28
ATE155137T1 (de) 1997-07-15
UA41348C2 (uk) 2001-09-17
YU2994A (sh) 1997-01-08
PL309989A1 (en) 1995-11-13
EP0681580A1 (en) 1995-11-15
MA23096A1 (fr) 1994-10-01
RU95117091A (ru) 1997-06-27
KR0169827B1 (en) 1999-01-15
PL178857B1 (pl) 2000-06-30
CN1097740A (zh) 1995-01-25
SK280929B6 (sk) 2000-09-12
HU9400209D0 (en) 1994-05-30
CA2152919C (en) 1999-01-05
FI940365A0 (fi) 1994-01-25
MX9400677A (es) 1994-08-31
JPH08501316A (ja) 1996-02-13
MY138629A (en) 2009-07-31
IL108384A (en) 1998-12-27
DE69312093D1 (de) 1997-08-14
US5270331A (en) 1993-12-14
HRP940034B1 (en) 2000-10-31
SI9300567A (en) 1994-09-30
AU678187B2 (en) 1997-05-22
JP2703825B2 (ja) 1998-01-26
EP0681580B1 (en) 1997-07-09
CZ181995A3 (en) 1996-06-12
AU5359894A (en) 1994-08-15
DK0681580T3 (da) 1997-08-18

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