NO904689D0 - Fremgangsmaate til fremstilling av imidazo(4,5-b)-kinolinyloksyalkansyreamider. - Google Patents

Fremgangsmaate til fremstilling av imidazo(4,5-b)-kinolinyloksyalkansyreamider.

Info

Publication number: NO904689D0
Authority: NO; Norway
Prior art keywords: cinolinyloxylkanic; acidamides; imidazo; procedure; preparation
Prior art date: 1989-11-01

Application number

NO904689A

Other languages

English (en)

Other versions

NO175531C (no

NO175531B (no

NO904689L (no

Inventor

Nicholas Meanwell

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-01

Filing date

1990-10-30

Publication date

1990-10-30

1990-10-30 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1990-10-30 Publication of NO904689D0 publication Critical patent/NO904689D0/no

1991-05-02 Publication of NO904689L publication Critical patent/NO904689L/no

1994-07-18 Publication of NO175531B publication Critical patent/NO175531B/no

1994-10-26 Publication of NO175531C publication Critical patent/NO175531C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO904689A 1989-11-01 1990-10-30 Analogifremgangsmåte til fremstilling av terapeutisk aktive imidazo(4,5-b)-kinolinyloksyalkansyreamider NO175531C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/430,228 US4943573A (en)	1989-11-01	1989-11-01	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility

Publications (4)

Publication Number	Publication Date
NO904689D0 true NO904689D0 (no)	1990-10-30
NO904689L NO904689L (no)	1991-05-02
NO175531B NO175531B (no)	1994-07-18
NO175531C NO175531C (no)	1994-10-26

Family

ID=23706624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO904689A NO175531C (no)	1989-11-01	1990-10-30	Analogifremgangsmåte til fremstilling av terapeutisk aktive imidazo(4,5-b)-kinolinyloksyalkansyreamider

Country Status (20)

Country	Link
US (1)	US4943573A (no)
EP (1)	EP0426180A3 (no)
JP (1)	JPH03169880A (no)
KR (1)	KR910009705A (no)
CN (1)	CN1025999C (no)
AU (1)	AU639033B2 (no)
CA (1)	CA2027935A1 (no)
EG (1)	EG19372A (no)
FI (1)	FI92697C (no)
HU (1)	HU209305B (no)
IE (1)	IE61579B1 (no)
IL (1)	IL96167A (no)
MY (1)	MY105308A (no)
NO (1)	NO175531C (no)
NZ (1)	NZ235868A (no)
OA (1)	OA09323A (no)
PT (1)	PT95765A (no)
RU (1)	RU2041210C1 (no)
YU (1)	YU205590A (no)
ZA (1)	ZA908725B (no)

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US4943573A (en) *	1989-11-01	1990-07-24	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
PH31245A (en) *	1991-10-30	1998-06-18	Janssen Pharmaceutica Nv	1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5208237A (en) *	1992-04-03	1993-05-04	Bristol-Meyers Squibb Company	7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5158958A (en) *	1992-04-03	1992-10-27	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5348960A (en) *	1992-04-03	1994-09-20	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5196428A (en) *	1992-04-03	1993-03-23	Bristol-Myers Squibb Company	Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5552267A (en) *	1992-04-03	1996-09-03	The Trustees Of Columbia University In The City Of New York	Solution for prolonged organ preservation
TW593317B (en)	1993-06-21	2004-06-21	Janssen Pharmaceutica Nv	Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
US5672622A (en) *	1994-04-21	1997-09-30	Berlex Laboratories, Inc.	Treatment of multiple sclerosis
US6060501A (en) *	1994-06-02	2000-05-09	Schering Aktiengesellschaft	Combined treatment of multiple sclerosis
WO1996005202A1 (fr) *	1994-08-17	1996-02-22	Nippon Hypox Laboratories Inc.	Derive de l'imidazoquinoleine
US5798767A (en) *	1996-03-15	1998-08-25	Rendition, Inc.	Method and apparatus for performing color space conversion using blend logic
SE9902987D0 (sv) *	1999-08-24	1999-08-24	Astra Pharma Prod	Novel compounds
US20030186963A1 (en) *	2001-09-14	2003-10-02	Dorwald Florencio Zaragoza	Substituted piperidines
JP4563675B2 (ja)	2001-10-12	2010-10-13	ハイ・ポイント・ファーマスーティカルズ、エルエルシー	置換ピペリジン類、およびヒスタミンｈ３受容体関連疾患の治療のためのその使用
US7064135B2 (en)	2001-10-12	2006-06-20	Novo Nordisk Inc.	Substituted piperidines
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
EP1928437A2 (en)	2005-08-26	2008-06-11	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
EP2258357A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis with acetylcholinesterase inhibitor
CA2625153A1 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
EP2026813A2 (en)	2006-05-09	2009-02-25	Braincells, Inc.	5 ht receptor mediated neurogenesis
AU2007249399A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
US8227603B2 (en) *	2006-08-01	2012-07-24	Cytokinetics, Inc.	Modulating skeletal muscle
US8299248B2 (en) *	2006-08-02	2012-10-30	Cytokinetics, Incorporated	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
PL2583970T3 (pl) *	2006-08-02	2016-05-31	Cytokinetics Inc	Określone cząstki chemiczne, kompozycje i sposoby zawierające imidazopirymidyny
MX2009002496A (es)	2006-09-08	2009-07-10	Braincells Inc	Combinaciones que contienen un derivado de 4-acilaminopiridina.
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
EP2139478A4 (en) *	2007-03-30	2010-05-05	Cytokinetics Inc	CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2527360B1 (en)	2007-06-04	2015-10-28	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
GB0808967D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substitute quinazolines
GB0808947D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substituted quinazolines
GB0808952D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substituted quinazolines
GB0808968D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substitute quinazolines
AU2009256157B2 (en)	2008-06-04	2014-12-18	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja)	2008-07-16	2011-11-17	シナジーファーマシューティカルズインコーポレイテッド	胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh)	2011-03-01	2018-10-19	辛纳吉制药公司	制备鸟苷酸环化酶c激动剂的方法
JP6145946B2 (ja)	2011-07-13	2017-06-14	サイトキネティックス，インコーポレイテッド	併用ａｌｓ療法
EP2804603A1 (en)	2012-01-10	2014-11-26	President and Fellows of Harvard College	Beta-cell replication promoting compounds and methods of their use
JP6499591B2 (ja)	2013-02-25	2019-04-10	シナジーファーマシューティカルズインコーポレイテッド	結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
JP2016514670A (ja)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
US9708367B2 (en)	2013-03-15	2017-07-18	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
EP4424697A2 (en)	2013-06-05	2024-09-04	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase c, method of making and using same
IL280864B2 (en)	2013-08-09	2024-03-01	Ardelyx Inc	Compounds and methods for inhibiting phosphate transport
EP3972599A1 (en)	2019-05-21	2022-03-30	Ardelyx, Inc.	Combination for lowering serum phosphate in a patient
WO2024149378A1 (zh) *	2023-01-13	2024-07-18	上海超阳药业有限公司	喹啉酮化合物和萘啶酮化合物及其用途

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US3932407A (en) *	1973-11-19	1976-01-13	Bristol-Myers Company	Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
NL7807507A (nl) *	1977-07-25	1979-01-29	Hoffmann La Roche	Tricyclische verbindingen.
US4490371A (en) *	1983-02-16	1984-12-25	Syntex (U.S.A.) Inc.	N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
DK69285A (da) *	1984-02-15	1985-08-16	Syntex Inc	Tetrahydroimidazolderivater
US4668686A (en) *	1985-04-25	1987-05-26	Bristol-Myers Company	Imidazoquinoline antithrombrogenic cardiotonic agents
US4775674A (en) *	1986-05-23	1988-10-04	Bristol-Myers Company	Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) *	1986-07-08	1987-10-20	Bristol-Myers Company	7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4943573A (en) *	1989-11-01	1990-07-24	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility

1989
- 1989-11-01 US US07/430,228 patent/US4943573A/en not_active Expired - Fee Related
1990
- 1990-10-18 CA CA002027935A patent/CA2027935A1/en not_active Abandoned
- 1990-10-29 NZ NZ235868A patent/NZ235868A/en unknown
- 1990-10-29 FI FI905326A patent/FI92697C/fi not_active IP Right Cessation
- 1990-10-30 IL IL9616790A patent/IL96167A/en not_active IP Right Cessation
- 1990-10-30 MY MYPI90001900A patent/MY105308A/en unknown
- 1990-10-30 YU YU205590A patent/YU205590A/sh unknown
- 1990-10-30 NO NO904689A patent/NO175531C/no unknown
- 1990-10-30 JP JP2290987A patent/JPH03169880A/ja active Pending
- 1990-10-31 ZA ZA908725A patent/ZA908725B/xx unknown
- 1990-10-31 PT PT95765A patent/PT95765A/pt not_active Application Discontinuation
- 1990-10-31 EP EP19900120952 patent/EP0426180A3/en not_active Ceased
- 1990-10-31 KR KR1019900017645A patent/KR910009705A/ko not_active Application Discontinuation
- 1990-10-31 IE IE392390A patent/IE61579B1/en not_active IP Right Cessation
- 1990-10-31 CN CN90108762A patent/CN1025999C/zh not_active Expired - Fee Related
- 1990-10-31 OA OA59882A patent/OA09323A/xx unknown
- 1990-10-31 RU SU904831618A patent/RU2041210C1/ru active
- 1990-10-31 AU AU65679/90A patent/AU639033B2/en not_active Ceased
- 1990-11-01 EG EG65590A patent/EG19372A/xx active
- 1990-11-01 HU HU906977A patent/HU209305B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1025999C (zh)	1994-09-28
NO175531C (no)	1994-10-26
PT95765A (pt)	1991-09-13
CN1051359A (zh)	1991-05-15
MY105308A (en)	1994-09-30
IL96167A (en)	1994-11-11
OA09323A (en)	1992-09-15
FI92697C (fi)	1994-12-27
AU6567990A (en)	1991-05-23
YU205590A (sh)	1992-09-07
RU2041210C1 (ru)	1995-08-09
AU639033B2 (en)	1993-07-15
HU906977D0 (en)	1991-05-28
FI92697B (fi)	1994-09-15
IE61579B1 (en)	1994-11-16
JPH03169880A (ja)	1991-07-23
KR910009705A (ko)	1991-06-28
CA2027935A1 (en)	1991-05-02
EP0426180A3 (en)	1992-01-08
EP0426180A2 (en)	1991-05-08
NZ235868A (en)	1993-12-23
US4943573A (en)	1990-07-24
FI905326A0 (fi)	1990-10-29
HUT56102A (en)	1991-07-29
ZA908725B (en)	1991-07-31
NO175531B (no)	1994-07-18
IE903923A1 (en)	1991-05-08
HU209305B (en)	1994-04-28
NO904689L (no)	1991-05-02
EG19372A (en)	1994-12-30
IL96167A0 (en)	1991-07-18

Publication	Publication Date	Title
NO904689L (no)	1991-05-02	Fremgangsmaate til fremstilling av imidazo(4,5-b)-kinolinyloksyalkansyreamider.
NO167392C (no)	1991-10-30	Fremgangsmaate for fremstilling av imidazopyridiner.
NO900830D0 (no)	1990-02-21	Fremgangsmaate for fremstilling av piperidinforbindelser.
NO890269D0 (no)	1989-01-20	Fremgangsmaate for fremstilling av 1,4-disubstituerte-piperidinyl-forbindelser.
NO902003L (no)	1990-11-09	Fremgangsmaate for fremstilling av n-heteroaryl-4-quinolinaminer.
NO900774L (no)	1990-08-22	Fremgangsmaate for fremstilling av polyamider.
BG95241A (bg)	1993-12-24	Метод за получаване на 2,9-дизаместени-4н-пиридо/1.2-а/ пиримидин-4-они
NO895067D0 (no)	1989-12-15	Fremgangsmaate til fremstilling av derivater av alfa, d-glukofuranose.
NO901554L (no)	1990-10-08	Fremgangsmaate for fremstilling av dinatrium-cefodizim.
NO874302L (no)	1988-04-18	Fremgangsmaate for fremstilling av 4,5-dihydro- og 4,5,6,7-tetrahydro- pyrazolo(1,5-a)pyrimidiner.
NO904285D0 (no)	1990-10-02	Fremgangsmaate for fremstilling av substituerte karboksytetrahydroisokinoliner.
NO905444D0 (no)	1990-12-18	Fremgangsmaate til fremstilling av oksazolderivater.
NO874888L (no)	1988-06-13	Fremgangsmaate til fremstilling av aminometyl-5,6,7,8-tetrahydronaftyloksyeddiksyrer.
NO901690L (no)	1990-10-19	Fremgangsmaate til fremstilling av substituerte azetidinylisotiazolpyridon-derivater.
ES518499A0 (es)	1983-10-01	Procedimiento para la preparacion de nuevas imidazo(1,2-a)pirimidinas.
NO903591D0 (no)	1990-08-15	Fremgangsmaate for fremstilling av pyrido(3,4-b)(1,4)benzoksazepiner samt anvendelse som medikamenter.
NO901067D0 (no)	1990-03-07	Fremgangsmaate for fremstilling av tiofener.
NO900969L (no)	1990-09-04	Fremgangsmaate for fremstilling av n-allymetatrifluormetylanilin.
NO882028L (no)	1988-11-30	Fremgangsmaate for fremstilling av cardiotone, tricykliskeimidazoloner.
FI874400A (fi)	1988-04-09	Foerfarande foer framstaellning av imidazo-4,5-b pyridin-2-on-derivat.
NO904060D0 (no)	1990-09-18	Fremgangsmaate for fremstilling av substituerte dibenzofuraner.
NO874617D0 (no)	1987-11-05	Fremgangsmaate til fremstilling av 2,6-diamino-3-halogenobenzylpyridiner.
NO880338D0 (no)	1988-01-26	Fremgangsmaate for fremstilling av cycloalkan (1,2-c:4,3-c)dipyrazole.
NO880409D0 (no)	1988-01-29	Fremgangsmaate for fremstilling av 14,15-substituerte lanosteroler.
NO880127L (no)	1988-07-15	Fremgangsmaate for fremstilling av (+-)-1,2-dihydro-3h-pyrrolo-(1,2-a)-pyrrol-1,7-dicarboxylater.