NO875358D0 - 6-benzoksazinyl- og 6-benzotiazinyl-2,3,4,5-tetrahydropyridazin-3-oner og fremgangsmaate for deres fremstilling. - Google Patents

6-benzoksazinyl- og 6-benzotiazinyl-2,3,4,5-tetrahydropyridazin-3-oner og fremgangsmaate for deres fremstilling.

Info

Publication number
NO875358D0
NO875358D0 NO1987875358A NO875358A NO875358D0 NO 875358 D0 NO875358 D0 NO 875358D0 NO 1987875358 A NO1987875358 A NO 1987875358A NO 875358 A NO875358 A NO 875358A NO 875358 D0 NO875358 D0 NO 875358D0
Authority
NO
Norway
Prior art keywords
benzotiazinyl
benzocsazinyl
tetrahydropyridazine
ones
procedures
Prior art date
Application number
NO1987875358A
Other languages
English (en)
Other versions
NO875358L (no
NO173653B (no
NO173653C (no
Inventor
Donald W Combs
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/944,316 external-priority patent/US4721784A/en
Priority claimed from US07/064,638 external-priority patent/US4766118A/en
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of NO875358D0 publication Critical patent/NO875358D0/no
Publication of NO875358L publication Critical patent/NO875358L/no
Priority to NO912800A priority Critical patent/NO912800D0/no
Priority to NO922610A priority patent/NO922610D0/no
Publication of NO173653B publication Critical patent/NO173653B/no
Publication of NO173653C publication Critical patent/NO173653C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/161,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO875358A 1986-12-22 1987-12-21 Analogifremgangsmaate for fresmstilling av terapeutisk aktive 6-benzoksazinyl-og 6-benzotianzinyl-2,3,4,5-tetrahydropyridazin-3-oner NO173653C (no)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NO912800A NO912800D0 (no) 1986-12-22 1991-07-17 Mellomprodukter.
NO922610A NO922610D0 (no) 1986-12-22 1992-07-02 Mellomprodukter

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/944,316 US4721784A (en) 1986-12-22 1986-12-22 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
US07/064,638 US4766118A (en) 1986-12-22 1987-06-22 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use
US12514287A 1987-12-02 1987-12-02

Publications (4)

Publication Number Publication Date
NO875358D0 true NO875358D0 (no) 1987-12-21
NO875358L NO875358L (no) 1988-06-23
NO173653B NO173653B (no) 1993-10-04
NO173653C NO173653C (no) 1994-01-12

Family

ID=27370654

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875358A NO173653C (no) 1986-12-22 1987-12-21 Analogifremgangsmaate for fresmstilling av terapeutisk aktive 6-benzoksazinyl-og 6-benzotianzinyl-2,3,4,5-tetrahydropyridazin-3-oner

Country Status (12)

Country Link
EP (1) EP0272914A3 (no)
KR (1) KR880007527A (no)
AU (2) AU607731B2 (no)
DK (1) DK673087A (no)
FI (1) FI86425C (no)
HU (1) HU207314B (no)
IL (1) IL84832A (no)
MY (2) MY102280A (no)
NO (1) NO173653C (no)
NZ (1) NZ222843A (no)
PH (1) PH24498A (no)
PT (1) PT86453B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3934436A1 (de) * 1989-06-01 1991-04-18 Thomae Gmbh Dr K 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
TW224941B (no) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
US5221742A (en) * 1990-12-21 1993-06-22 Ortho Pharmaceutical Corporation Process for the preparation of 6-(3,4-dihydro-3-oxo-1,4(2h)-benzoxazin-7-yl)-2,3,4,5-tetrahydropyridazin-3-ones
AU1493092A (en) * 1991-04-18 1992-10-22 Ortho Pharmaceutical Corporation (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones
HUP0400257A2 (hu) * 1995-09-22 2004-05-28 Sumitomo Chemical Co., Ltd. Herbicid hatású pirazin-2-on-származékok, ezek alkalmazása és előállításuk során alkalmazható intermedierek
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
WO2005099688A2 (en) 2004-04-07 2005-10-27 Takeda Pharmaceutical Company Limited Cyclic compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US20070225217A1 (en) 2005-11-09 2007-09-27 Combinatorx, Incorporated Methods, compositions, and kits for the treatment of medical conditions
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2559319T3 (es) 2007-06-04 2016-02-11 Synergy Pharmaceuticals Inc. Agonistas de guanilato cliclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012118972A2 (en) 2011-03-01 2012-09-07 Synegy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
PT3004138T (pt) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
IL280864B2 (en) 2013-08-09 2024-03-01 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
EP3972599A1 (en) 2019-05-21 2022-03-30 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (no) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
FR2588868B1 (fr) * 1985-10-21 1988-11-10 Negma Laboratoires Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
TW224941B (no) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd

Also Published As

Publication number Publication date
PT86453B (pt) 1990-11-20
AU6808690A (en) 1991-04-26
EP0272914A3 (en) 1990-04-04
HU207314B (en) 1993-03-29
FI86425B (fi) 1992-05-15
EP0272914A2 (en) 1988-06-29
MY102280A (en) 1992-05-15
NO875358L (no) 1988-06-23
PT86453A (en) 1988-01-01
DK673087A (da) 1988-06-23
NO173653B (no) 1993-10-04
FI875619A (fi) 1988-06-23
FI86425C (fi) 1992-08-25
KR880007527A (ko) 1988-08-27
PH24498A (en) 1990-07-18
HUT48624A (en) 1989-06-28
NZ222843A (en) 1989-10-27
AU633666B2 (en) 1993-02-04
NO173653C (no) 1994-01-12
IL84832A (en) 1993-01-14
FI875619A0 (fi) 1987-12-21
AU607731B2 (en) 1991-03-14
DK673087D0 (da) 1987-12-21
AU8293287A (en) 1988-06-23
MY106781A (en) 1995-07-31
IL84832A0 (en) 1988-06-30

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