NO20015398D0 - Endoparasiticidal synergistic combination containing cyclic depsipeptides and piperazines - Google Patents

Endoparasiticidal synergistic combination containing cyclic depsipeptides and piperazines

Info

Publication number
NO20015398D0
NO20015398D0 NO20015398A NO20015398A NO20015398D0 NO 20015398 D0 NO20015398 D0 NO 20015398D0 NO 20015398 A NO20015398 A NO 20015398A NO 20015398 A NO20015398 A NO 20015398A NO 20015398 D0 NO20015398 D0 NO 20015398D0
Authority
NO
Norway
Prior art keywords
endoparasiticidal
piperazines
depsipeptides
cyclic depsipeptides
containing cyclic
Prior art date
Application number
NO20015398A
Other languages
Norwegian (no)
Other versions
NO328870B1 (en
NO20015398L (en
Inventor
Achim Harder
Georg Samson-Himmelstjerna
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7907825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20015398(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO20015398L publication Critical patent/NO20015398L/en
Publication of NO20015398D0 publication Critical patent/NO20015398D0/en
Publication of NO328870B1 publication Critical patent/NO328870B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention relates to the use of piperazines for potentiating the endoparasiticidal action of cyclic depsipeptides in endoparasiticidal agents. Said depsipeptides are comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms. The invention also relates to agents of this type and to the use of piperazines and cyclic depsipeptides, said depsipeptides being comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms, in order to produce endoparasiticidal agents.
NO20015398A 1999-05-12 2001-11-05 Endoparasitic agents containing cyclic depsipeptides and piperazines and use of piperazines with cyclic depsipeptides NO328870B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19921887A DE19921887A1 (en) 1999-05-12 1999-05-12 Synergistic ectoparasiticide combination for use in human or veterinary medicine, comprising cyclic depsipeptide and piperazine compound as potentiating agent
PCT/EP2000/004014 WO2000069425A2 (en) 1999-05-12 2000-05-04 Endoparasiticidal synergistic combination containing cyclic depsipeptides and piperazines

Publications (3)

Publication Number Publication Date
NO20015398L NO20015398L (en) 2001-11-05
NO20015398D0 true NO20015398D0 (en) 2001-11-05
NO328870B1 NO328870B1 (en) 2010-06-07

Family

ID=7907825

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015398A NO328870B1 (en) 1999-05-12 2001-11-05 Endoparasitic agents containing cyclic depsipeptides and piperazines and use of piperazines with cyclic depsipeptides

Country Status (26)

Country Link
EP (1) EP1189615B1 (en)
JP (1) JP2002544224A (en)
KR (1) KR100704717B1 (en)
CN (1) CN1224391C (en)
AT (1) ATE258795T1 (en)
AU (1) AU768910B2 (en)
BR (1) BR0010499A (en)
CA (1) CA2373827C (en)
CZ (1) CZ300782B6 (en)
DE (2) DE19921887A1 (en)
DK (1) DK1189615T3 (en)
ES (1) ES2211558T3 (en)
HK (1) HK1047228B (en)
HR (1) HRP20010918B1 (en)
HU (1) HUP0201201A3 (en)
MX (1) MXPA01011455A (en)
NO (1) NO328870B1 (en)
PL (1) PL200951B1 (en)
PT (1) PT1189615E (en)
RS (1) RS50169B (en)
RU (1) RU2250779C2 (en)
SK (1) SK285494B6 (en)
TR (2) TR200103240T2 (en)
UA (1) UA72520C2 (en)
WO (1) WO2000069425A2 (en)
ZA (1) ZA200108238B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10008128A1 (en) * 2000-02-22 2001-08-23 Bayer Ag Endoparasiticide composition effective on topical administration, comprises solution of depsipeptide in solvent such as 1,2-isopropylidene-glycerol
DE10358525A1 (en) 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasiticides Means for topical application
KR101671325B1 (en) * 2015-01-09 2016-11-02 한국생명공학연구원 Novel cyclic depsipeptide-based compound, separation method thereof, and antibacterial pharmaceutical composition containing the same as an active ingredient
WO2016187534A1 (en) 2015-05-20 2016-11-24 Merial, Inc. Anthelmintic depsipeptide compounds
SG11201805368YA (en) * 2015-12-28 2018-07-30 Merial Inc Anthelmintic depsipeptide compounds
MX2019005628A (en) 2016-11-16 2019-12-18 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic depsipeptide compounds.
US20230339874A1 (en) * 2020-09-11 2023-10-26 The Governing Council Of The University Of Toronto Piperazinyl compounds and methods for treating nematode infections

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA842571B (en) * 1983-04-07 1985-11-27 Merck & Co Inc Novel synergistic antiparasitic combinations
JPS6471865A (en) * 1987-09-11 1989-03-16 Nichibai Boeki Kk 1-alkylcarbamoyl-4-methylpiperazine derivative
NO176766C (en) * 1989-02-07 1995-05-24 Meiji Seika Kaisha Process for the preparation of a compound having anthelmintic activity
BR9407711A (en) * 1993-09-06 1997-02-12 Fujisawa Pharmaceutical Co Process cyclopeptide compound for the preparation of a cyclopeptide and parasiticide compound
DE4400464A1 (en) * 1994-01-11 1995-07-13 Bayer Ag Endoparasiticidal agents
DE19520275A1 (en) * 1995-06-02 1996-12-05 Bayer Ag Endoparasiticidal agents
EP0863907A1 (en) * 1995-09-07 1998-09-16 PHARMACIA & UPJOHN COMPANY Cycloanthelmintic inhibitors
AU6229898A (en) * 1997-02-19 1998-09-09 Bayer Aktiengesellschaft Derivatives of cyclodepsipeptide, pf1022 substance
CN1076349C (en) * 1997-06-04 2001-12-19 拜尔公司 Desoxycyclodepsipeptides and their use for combatting endoparasites
WO2000008047A1 (en) * 1998-08-04 2000-02-17 Nisshin Flour Milling Co., Ltd. Depsipeptide derivatives bearing piperazinone rings

Also Published As

Publication number Publication date
EP1189615B1 (en) 2004-02-04
DK1189615T3 (en) 2004-06-07
EP1189615A2 (en) 2002-03-27
CZ300782B6 (en) 2009-08-12
PT1189615E (en) 2004-05-31
WO2000069425A2 (en) 2000-11-23
PL200951B1 (en) 2009-02-27
NO328870B1 (en) 2010-06-07
PL351376A1 (en) 2003-04-07
CA2373827A1 (en) 2000-11-23
AU5523700A (en) 2000-12-05
TR200103240T2 (en) 2002-04-22
HRP20010918B1 (en) 2011-01-31
HK1047228A1 (en) 2003-02-14
CZ20014060A3 (en) 2002-06-12
HUP0201201A2 (en) 2002-08-28
NO20015398L (en) 2001-11-05
JP2002544224A (en) 2002-12-24
TR200401875T2 (en) 2005-01-24
RS50169B (en) 2009-05-06
CA2373827C (en) 2008-09-16
BR0010499A (en) 2002-02-13
YU80501A (en) 2004-09-03
AU768910B2 (en) 2004-01-08
ATE258795T1 (en) 2004-02-15
ES2211558T3 (en) 2004-07-16
SK16262001A3 (en) 2002-03-05
ZA200108238B (en) 2002-12-24
KR20010109527A (en) 2001-12-10
DE50005213D1 (en) 2004-03-11
RU2250779C2 (en) 2005-04-27
UA72520C2 (en) 2005-03-15
HUP0201201A3 (en) 2003-03-28
KR100704717B1 (en) 2007-04-09
MXPA01011455A (en) 2002-07-30
SK285494B6 (en) 2007-02-01
HRP20010918A2 (en) 2003-04-30
HK1047228B (en) 2006-07-21
DE19921887A1 (en) 2000-11-16
CN1352559A (en) 2002-06-05
WO2000069425A3 (en) 2001-03-15
CN1224391C (en) 2005-10-26

Similar Documents

Publication Publication Date Title
ATE383169T1 (en) COMPONENT AND COMPOSITIONS FOR ADMINISTRATION OF ACTIVE INGREDIENTS
ATE257386T1 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF SELF-CROSS-LINKED AND NON-SELF-CROSS-LINKED HYALURONIC ACID FOR THE TREATMENT OF ARTHROPATHIES
TR200201874T2 (en) New compounds and compositions as protease inhibitors.
TR200103428T2 (en) IMPDH enzyme inhibitors.
PT883687E (en) RECEPTORS OF CHIMIOCINES C-C, CKR-5, CC, THEIR DERIVATIVES AND THEIR USES
DE60024414T2 (en) OXADIAZOL COMPOUNDS AND COMPOSITIONS FOR THE DISPOSAL OF ACTIVE SUBSTANCES
YU13301A (en) Muscarinic agonists and antagonists
DK1228097T3 (en) Antimicrobial activity of the first cationic human lactoferrin cluster
RS50148B (en) Use of docetaxel for treating hepatocellular carcinoma
NO20015398L (en) Endoparasiticidal synergistic combination containing cyclic depsipeptides and piperazines
TR200402070T4 (en) Cyclobutene-dione derivatives and their use in the treatment of arteriosclerosis
NO306292B1 (en) Triarylethylene derivatives for use in therapy
DE60024977D1 (en) CLONING AND EXPRESSION OF HAEMOPHILUS SOMNUS TRANSFERRIN-BINDING PROTEINS
TR200103126T2 (en) Anticonvulsant derivatives for use in the improvement of structural tremor
UA37545A (en) POTASSIUM SALT of N-(1,4-DIOXO-3-METHYL-1,4-DIHYDRONAPHTh-2-YL) GLYCINE, REVEALING anti -hypoxic and anti-ischemic action

Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

MM1K Lapsed by not paying the annual fees