NO20006282L - Nye cyklosporiner - Google Patents

Nye cyklosporiner

Info

Publication number
NO20006282L
NO20006282L NO20006282A NO20006282A NO20006282L NO 20006282 L NO20006282 L NO 20006282L NO 20006282 A NO20006282 A NO 20006282A NO 20006282 A NO20006282 A NO 20006282A NO 20006282 L NO20006282 L NO 20006282L
Authority
NO
Norway
Prior art keywords
cyclosporins
new
new cyclosporins
letters
compounds
Prior art date
Application number
NO20006282A
Other languages
English (en)
Other versions
NO20006282D0 (no
Inventor
Ernst Ellmerer-Mueller
Dagmar Broessner
Najib Maslouh
Horst-Dieter Ambrosi
Gerhard Jas
Gunter Fischer
Original Assignee
Chem Ag C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ag C filed Critical Chem Ag C
Publication of NO20006282D0 publication Critical patent/NO20006282D0/no
Publication of NO20006282L publication Critical patent/NO20006282L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Forbindelser med formel (I) B¿C¿D¿E ¿F \ V---K---l---H--- og deres farmasøytisk akseptable salter der bokstavene A til L har betydningene som er angitt i beskrivelsen og fremgangsmåter for deres fremstilling og deres anvendelser.
NO20006282A 1998-06-12 2000-12-11 Nye cyklosporiner NO20006282L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98110761 1998-06-12
PCT/EP1999/004012 WO1999065933A1 (en) 1998-06-12 1999-06-10 Novel cyclosporins

Publications (2)

Publication Number Publication Date
NO20006282D0 NO20006282D0 (no) 2000-12-11
NO20006282L true NO20006282L (no) 2001-02-12

Family

ID=8232110

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006282A NO20006282L (no) 1998-06-12 2000-12-11 Nye cyklosporiner

Country Status (19)

Country Link
US (1) US6583265B1 (no)
EP (1) EP1086124B1 (no)
JP (1) JP4477777B2 (no)
KR (1) KR20010052766A (no)
CN (1) CN1205220C (no)
AT (1) ATE254630T1 (no)
AU (1) AU760168B2 (no)
BR (1) BR9911160A (no)
CA (1) CA2334730C (no)
DE (1) DE69912952T2 (no)
DK (1) DK1086124T3 (no)
ES (1) ES2212583T3 (no)
HU (1) HUP0102833A3 (no)
IL (1) IL139825A0 (no)
MX (1) MXPA00012218A (no)
NO (1) NO20006282L (no)
PL (1) PL344599A1 (no)
PT (1) PT1086124E (no)
WO (1) WO1999065933A1 (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001237939A1 (en) * 2000-02-08 2001-08-20 Gulgun Tezel Methods for treating glaucoma
US6784156B2 (en) 2001-03-05 2004-08-31 Enanta Pharmaceuticals, Inc. Cyclosporins for the treatment of respiratory diseases
KR100465012B1 (ko) * 2001-05-11 2005-01-13 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US20030087813A1 (en) 2001-10-12 2003-05-08 Or Yat Sun Cyclosporin analogs for the treatment of lung diseases
KR20040039622A (ko) * 2002-11-04 2004-05-12 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US7012065B2 (en) 2003-02-07 2006-03-14 Enanta Pharmaceuticals, Inc. Cyclosporins for the treatment of immune disorders
AU2005230400A1 (en) * 2004-04-08 2005-10-20 Novartis Ag Use of cyclosporins for treatment of cerebral ischemia and brain and spinal cord injury
US7196161B2 (en) * 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
WO2007041631A1 (en) 2005-09-30 2007-04-12 Scynexis, Inc. ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
BRPI0616476A2 (pt) * 2005-09-30 2011-06-21 Scynexis Inc uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica
CA2652662C (en) * 2006-05-19 2015-11-03 Scynexis, Inc. Methods for the treatment and prevention of ocular disorders
JP2009539292A (ja) * 2006-06-02 2009-11-12 ぺリション、クロード、アニー 活性電子の管理
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
US20080255038A1 (en) * 2007-04-11 2008-10-16 Samuel Earl Hopkins Pharmaceutical compositions
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
JP5820722B2 (ja) 2008-06-06 2015-11-24 スシネキス インク シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用
EP2313157A2 (en) 2008-07-10 2011-04-27 Allergan, Inc. Cyclosporin derivatives for treating ocular and dermal diseases and conditions
EP2376524B1 (en) * 2008-12-31 2017-03-15 Cypralis Limited Derivatives of cyclosporin a
US20100305047A1 (en) * 2009-05-27 2010-12-02 Allergan, Inc. Cyclosporin derivatives for enhancing the growth of hair
EP2435065A1 (en) * 2009-05-27 2012-04-04 Allergan, Inc. Cyclosporin derivatives for treating inflammatory diseases and conditions
US20120010131A1 (en) 2009-12-30 2012-01-12 Scynexis, Inc. Novel cyclosporin analogues
CN107007815A (zh) 2010-07-16 2017-08-04 美国科技环球有限公司 新颖的环孢霉素a衍生物在病毒感染的治疗和预防中的应用
WO2012021796A2 (en) 2010-08-12 2012-02-16 S&T Global, Inc. Novel cyclosporin derivatives for the treatment and prevention of a viral infection
BR112013008864A2 (pt) * 2010-10-12 2016-06-28 Allergan Inc análogos d ciclosporina
US9175042B2 (en) * 2010-10-12 2015-11-03 Allergan, Inc. Cyclosporin analogs
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
KR102011339B1 (ko) 2010-12-15 2019-08-16 콘트라빌 파마슈티컬스, 인코퍼레이티드 아미노산 1 및 3에서 변형된 사이클로스포린 유사체 분자
GB201711749D0 (en) * 2017-07-21 2017-09-06 Cypralis Ltd Cyclosporin analogues and uses thereof
CN111449050A (zh) 2019-01-20 2020-07-28 睿诺医疗科技（上海）有限公司 环孢菌素类似物及其用途
CA3152922A1 (en) * 2019-10-12 2021-04-15 Michael Peel Treatment and prevention of nephrotoxin-induced kidney injuries
EP4126905A4 (en) 2020-03-26 2024-05-29 Farsight Medical Technology (Shanghai) Co., Ltd. CYCLOPHILIN INHIBITORS AND THEIR USES
TW202143995A (zh) * 2020-04-15 2021-12-01 大陸商睿諾醫療科技（上海）有限公司 器官損傷的預防和治療
GB202207348D0 (en) 2022-05-19 2022-07-06 Cypralis Ltd Macrocyclic compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
NZ315324A (en) 1995-07-17 1999-10-28 Chem Ag C Cyclosporin derivatives with anti-hiv effect
FR2757522B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757520B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
FR2757521B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HUP0102833A2 (hu) 2002-01-28
CA2334730C (en) 2009-09-29
AU760168B2 (en) 2003-05-08
CA2334730A1 (en) 1999-12-23
PL344599A1 (en) 2001-11-05
KR20010052766A (ko) 2001-06-25
MXPA00012218A (es) 2002-04-24
CN1205220C (zh) 2005-06-08
IL139825A0 (en) 2002-02-10
JP4477777B2 (ja) 2010-06-09
EP1086124A1 (en) 2001-03-28
NO20006282D0 (no) 2000-12-11
EP1086124B1 (en) 2003-11-19
WO1999065933A1 (en) 1999-12-23
DE69912952T2 (de) 2004-09-02
AU4899399A (en) 2000-01-05
BR9911160A (pt) 2001-04-03
DK1086124T3 (da) 2004-03-29
ATE254630T1 (de) 2003-12-15
DE69912952D1 (en) 2003-12-24
PT1086124E (pt) 2004-04-30
US6583265B1 (en) 2003-06-24
ES2212583T3 (es) 2004-07-16
CN1305493A (zh) 2001-07-25
HUP0102833A3 (en) 2002-03-28
JP2002518406A (ja) 2002-06-25

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