NO171679C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-fenyl-3-(1-piperazinyl)-1h-indazoler - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-fenyl-3-(1-piperazinyl)-1h-indazoler

Info

Publication number
NO171679C
NO171679C NO883465A NO883465A NO171679C NO 171679 C NO171679 C NO 171679C NO 883465 A NO883465 A NO 883465A NO 883465 A NO883465 A NO 883465A NO 171679 C NO171679 C NO 171679C
Authority
NO
Norway
Prior art keywords
indazoles
piperazinyl
phenyl
preparation
therapeutic active
Prior art date
Application number
NO883465A
Other languages
English (en)
Norwegian (no)
Other versions
NO171679B (no
NO883465L (no
NO883465D0 (no
Inventor
Joseph Thomas Strupczewski
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO883465D0 publication Critical patent/NO883465D0/no
Publication of NO883465L publication Critical patent/NO883465L/no
Priority to NO921809A priority Critical patent/NO921809D0/no
Publication of NO171679B publication Critical patent/NO171679B/no
Publication of NO171679C publication Critical patent/NO171679C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO883465A 1987-08-07 1988-08-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-fenyl-3-(1-piperazinyl)-1h-indazoler NO171679C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO921809A NO921809D0 (no) 1987-08-07 1992-05-07 Fremgangsmaate og mellomprodukter for fremstilling av 1-fenyl-3-(1-piperazinyl)-1h-indazoler, og anvendelse derav som medikamenter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8276087A 1987-08-07 1987-08-07

Publications (4)

Publication Number Publication Date
NO883465D0 NO883465D0 (no) 1988-08-04
NO883465L NO883465L (no) 1989-02-08
NO171679B NO171679B (no) 1993-01-11
NO171679C true NO171679C (no) 1993-04-21

Family

ID=22173273

Family Applications (1)

Application Number Title Priority Date Filing Date
NO883465A NO171679C (no) 1987-08-07 1988-08-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-fenyl-3-(1-piperazinyl)-1h-indazoler

Country Status (11)

Country Link
EP (1) EP0302423A3 (ko)
JP (1) JPS6466171A (ko)
KR (1) KR890003730A (ko)
AU (2) AU607792B2 (ko)
DK (1) DK440488A (ko)
FI (1) FI883646A (ko)
IL (1) IL87361A0 (ko)
NO (1) NO171679C (ko)
NZ (1) NZ225714A (ko)
PT (1) PT88202A (ko)
ZA (1) ZA885766B (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4999356A (en) * 1987-08-07 1991-03-12 Hoechst-Roussel Pharmaceuticals, Inc. 1-phenyl-3-(1-piperazinyl)-1H-indazoles
NZ230045A (en) 1988-08-05 1990-11-27 Janssen Pharmaceutica Nv 3-piperazinylbenzazole derivatives and pharmaceutical compositions
US5015740A (en) * 1988-08-05 1991-05-14 Janssen Pharmaceutica N.V. Antipsychotic 3-piperazinylbenzazole derivatives
US4957916A (en) * 1988-08-05 1990-09-18 Janssen Pharmaceutica N.V. Antipsychotic 3-piperazinylbenzazole derivatives
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5561128A (en) * 1989-05-19 1996-10-01 Hoechst-Roussel Pharmaceuticals, Inc. N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US4954503A (en) * 1989-09-11 1990-09-04 Hoechst-Roussel Pharmaceuticals, Inc. 3-(1-substituted-4-piperazinyl)-1H-indazoles
US5041445A (en) * 1990-05-21 1991-08-20 Hoechst-Roussel Pharmaceuticals Incorporated 3-[1-thiazolidinylbutyl-4-piperazinyl]-1H-indazoles
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DK55192D0 (da) * 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
JP3462501B2 (ja) * 1992-11-23 2003-11-05 アベンティス・ファーマスーティカルズ・インコーポレイテツド 置換された3−(アミノアルキルアミノ)−1,2−ベンゾイソキサゾールおよび関連化合物
EP0833820B1 (en) * 1995-06-06 2001-02-14 Aventis Pharmaceuticals Inc. Benzisoxazole and indazole derivatives as antipsychotic agents
IL126745A (en) * 1997-11-04 2003-09-17 Pfizer Prod Inc Methods of preparing 4-cyano-4- (substituted indazole) cyclohexanecarboxylic acids useful as pde4 inhibitors
JP2014166961A (ja) * 2011-06-20 2014-09-11 Dainippon Sumitomo Pharma Co Ltd 新規インダゾール誘導体

Also Published As

Publication number Publication date
DK440488D0 (da) 1988-08-05
FI883646A0 (fi) 1988-08-04
EP0302423A2 (en) 1989-02-08
EP0302423A3 (en) 1991-01-09
IL87361A0 (en) 1989-01-31
JPS6466171A (en) 1989-03-13
NO171679B (no) 1993-01-11
AU2043488A (en) 1989-02-09
NO883465L (no) 1989-02-08
NO883465D0 (no) 1988-08-04
AU607792B2 (en) 1991-03-14
ZA885766B (en) 1989-07-26
DK440488A (da) 1989-02-08
FI883646A (fi) 1989-02-08
KR890003730A (ko) 1989-04-17
NZ225714A (en) 1991-12-23
AU6824290A (en) 1991-03-14
PT88202A (pt) 1989-06-30

Similar Documents

Publication Publication Date Title
NO169439C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive oxadiazoler
NO883974D0 (no) Fremgangsmaate for fremstilling av terapeutiske aktive tetrahydro-hydroksypyranon-derivater.
NO164025C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-imidazolylmetyl-tetrahydrokarbazolon-derivater.
NO884154L (no) Fremgangsmaate for fremstilling av terapeutisk aktive preparater.
NO167202C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive (1h-imidazol-1-ylmetyl)-substituerte benzimidazolderivater.
NO156785C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cyklobutan-derivater.
NO169900C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive (ih-azol-1-ylmetyl)substituerte benzotriazolderivater
NO172048C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazoler
NO874153D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo-benzoksazinon-derivater.
NO161497C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 9a-aza-9a-homoerytromycin-derivater.
NO172575C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzocykloalkanderivater
NO171679C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-fenyl-3-(1-piperazinyl)-1h-indazoler
NO871028D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazol- og oksazol-derivater.
NO164541C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater.
NO167734C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte aminderivater.
NO167664C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive castanosperminestere og glycosider.
NO902710L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive r(-) 3-kinuklidinol-derivater.
NO873680L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive sulfonamido-etyl-forbindelser.
NO159090C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoindol-derivater.
NO164899C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolylindolforbindelser.
NO162188C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoliner.
NO170086C (no) Fremgangsmaate for fremstilling av terapeutisk aktive 5-(omega-ammonio-acyloksy-metylen)-tetrahydrofuraner og -tetrahydrotiofener
NO874780D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolo-benzimidazol-derivater.
NO163617C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolidinon-derivater.
NO882281D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive pyrazinamider.