NO167026C - Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater

Info

Publication number: NO167026C
Authority: NO; Norway
Prior art keywords: preparation; therapeutic active; analogy procedure; benzimidazold; derivatives
Prior art date: 1985-09-11

Application number

NO863608A

Other languages

English (en)

Norwegian (no)

Other versions

NO167026B (no

NO863608D0 (no

NO863608L (no

Inventor

Philippe Manoury

Jean Binet

Gerard Defosse

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-11

Filing date

1986-09-10

Publication date

1991-09-25

1986-09-10 Application filed by Synthelabo filed Critical Synthelabo

1986-09-10 Publication of NO863608D0 publication Critical patent/NO863608D0/no

1987-03-12 Publication of NO863608L publication Critical patent/NO863608L/no

1991-06-17 Publication of NO167026B publication Critical patent/NO167026B/no

1991-09-25 Publication of NO167026C publication Critical patent/NO167026C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO863608A 1985-09-11 1986-09-10 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater NO167026C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8513453A FR2587029B1 (fr)	1985-09-11	1985-09-11	Derives de benzimidazole, leur preparation et leur application en therapeutique

Publications (4)

Publication Number	Publication Date
NO863608D0 NO863608D0 (no)	1986-09-10
NO863608L NO863608L (no)	1987-03-12
NO167026B NO167026B (no)	1991-06-17
NO167026C true NO167026C (no)	1991-09-25

Family

ID=9322797

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO863608A NO167026C (no)	1985-09-11	1986-09-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
NO2001017C NO2001017I1 (no)	1985-09-11	2001-10-15	Mizolastine

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO2001017C NO2001017I1 (no)	1985-09-11	2001-10-15	Mizolastine

Country Status (25)

Country	Link
US (2)	US4820710A (xx)
EP (1)	EP0217700B1 (xx)
JP (1)	JPS6261979A (xx)
KR (1)	KR930001411B1 (xx)
AR (1)	AR243187A1 (xx)
AT (1)	ATE103603T1 (xx)
AU (1)	AU582894B2 (xx)
CA (1)	CA1272486A (xx)
CS (1)	CS357991A3 (xx)
DE (2)	DE3689748T2 (xx)
DK (1)	DK170594B1 (xx)
ES (1)	ES2001782A6 (xx)
FI (1)	FI87210C (xx)
FR (1)	FR2587029B1 (xx)
GR (1)	GR862318B (xx)
HK (1)	HK1005592A1 (xx)
HU (1)	HU196597B (xx)
IE (1)	IE61607B1 (xx)
IL (1)	IL79992A (xx)
LU (1)	LU90085I2 (xx)
NL (1)	NL970029I2 (xx)
NO (2)	NO167026C (xx)
NZ (1)	NZ217537A (xx)
PT (1)	PT83355B (xx)
ZA (1)	ZA866901B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2618435B1 (fr) *	1987-07-23	1989-10-27	Synthelabo	Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2637595B1 (fr) *	1988-10-11	1990-11-30	Synthelabo	Derives de benzimidazole, leur preparation et leur application en therapeutique
JPH02294758A (ja) *	1989-05-09	1990-12-05	Nec Corp	計算機使用時間管理方式
FR2658823B1 (fr) *	1990-02-27	1992-04-30	Adir	Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent .
FR2666582B1 (fr) *	1990-09-07	1994-09-02	Synthelabo	Derives de benzimidazole, leur preparation et leur application en therapeutique.
FR2693194B1 (fr) *	1992-07-03	1994-09-23	Synthelabo	Dérivés d'alcanecarboxamide, leur préparation et leur application thérapeutique.
FR2745500B1 (fr) *	1996-03-04	1998-04-03	Synthelabo	Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
JPH10101564A (ja) *	1996-09-27	1998-04-21	Mitsubishi Chem Corp	鼻炎予防及び／又は治療剤
US6369235B1 (en)	1997-02-25	2002-04-09	The United States Of America As Represented By The Department Of Health And Human Services	Substituted benzimidazoles, and methods of use thereof, for the inhibition of HIV reverse transcription and for the treatment of HIV infection
FR2762214B1 (fr) *	1997-04-17	2000-10-06	Synthelabo	Utilisation de la mizolastine pour la preparation d'un medicament destine au traitement de l'inflammation
EP0958820A1 (en) *	1998-05-19	1999-11-24	Sanofi-Synthelabo	Use of an imidazol derivative for the manufacture of a medicament for treating auto-immunodiseases
ES2208098B1 (es) *	2002-10-02	2005-10-16	Ragactives, S.L.	Procedimiento e intermedios para la obtencion de derivados de 1-(1h-bencimidazol-2-il)-4-(2-aminopirimidin) piperidina.
AR045955A1 (es) *	2003-09-30	2005-11-16	Janssen Pharmaceutica Nv	Compuestos benzoimidazolicos
ES2245227B1 (es) *	2004-04-06	2007-03-01	Ragactives, S.L.	Formas cristalinas de mizolastina, procedimientos para su obtencion y composiciones farmaceuticas que las contienen.
AU2010266040B2 (en) *	2009-06-25	2015-01-15	Alkermes Pharma Ireland Limited	Prodrugs of NH-acidic compounds
EP2445502B2 (en)	2009-06-25	2022-09-28	Alkermes Pharma Ireland Limited	Heterocyclic compounds for the treatment of neurological and psychological disorders
CN102140076A (zh) *	2010-02-03	2011-08-03	辽宁本源制药有限公司	咪唑斯汀中间体的制备
ES2715562T3 (es)	2011-12-15	2019-06-04	Alkermes Pharma Ireland Ltd	Profármacos de compuestos de amina secundaria
CN112423754A (zh)	2018-03-05	2021-02-26	奥克梅斯制药爱尔兰有限公司	阿立哌唑的给药策略
KR20210136106A (ko) *	2019-04-11	2021-11-16	데이진 화-마 가부시키가이샤	벤즈이미다졸 유도체 및 이들의 용도
US12084453B2 (en)	2021-12-10	2024-09-10	Incyte Corporation	Bicyclic amines as CDK12 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4281005A (en) *	1979-03-05	1981-07-28	Merck & Co., Inc.	Novel 2-pyridylimidazole compounds
US4556660A (en) *	1982-07-12	1985-12-03	Janssen Pharmaceutica N.V.	N-(Bicyclic heterocyclyl)-4-piperidinamines
DE3484096D1 (de) *	1983-11-30	1991-03-14	Janssen Pharmaceutica Nv	Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
US4588722A (en) *	1984-01-09	1986-05-13	Janssen Pharmaceutica N.V.	N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines

1985
- 1985-09-11 FR FR8513453A patent/FR2587029B1/fr not_active Expired
1986
- 1986-09-02 DE DE3689748T patent/DE3689748T2/de not_active Expired - Lifetime
- 1986-09-02 EP EP86401928A patent/EP0217700B1/fr not_active Expired - Lifetime
- 1986-09-02 DE DE1997175081 patent/DE19775081I2/de active Active
- 1986-09-02 AT AT86401928T patent/ATE103603T1/de active
- 1986-09-09 IL IL79992A patent/IL79992A/xx not_active IP Right Cessation
- 1986-09-10 AU AU62552/86A patent/AU582894B2/en not_active Expired
- 1986-09-10 IE IE241686A patent/IE61607B1/en not_active IP Right Cessation
- 1986-09-10 HU HU863907A patent/HU196597B/hu unknown
- 1986-09-10 ZA ZA866901A patent/ZA866901B/xx unknown
- 1986-09-10 DK DK431586A patent/DK170594B1/da not_active IP Right Cessation
- 1986-09-10 KR KR1019860007594A patent/KR930001411B1/ko not_active IP Right Cessation
- 1986-09-10 GR GR862318A patent/GR862318B/el unknown
- 1986-09-10 AR AR86305197A patent/AR243187A1/es active
- 1986-09-10 FI FI863661A patent/FI87210C/fi not_active IP Right Cessation
- 1986-09-10 JP JP61214978A patent/JPS6261979A/ja active Granted
- 1986-09-10 PT PT83355A patent/PT83355B/pt unknown
- 1986-09-10 NO NO863608A patent/NO167026C/no not_active IP Right Cessation
- 1986-09-10 CA CA000517916A patent/CA1272486A/en not_active Expired - Lifetime
- 1986-09-10 US US06/906,279 patent/US4820710A/en not_active Expired - Lifetime
- 1986-09-10 ES ES8601773A patent/ES2001782A6/es not_active Expired
- 1986-09-10 NZ NZ217537A patent/NZ217537A/xx unknown
1988
- 1988-12-12 US US07/283,468 patent/US4912219A/en not_active Expired - Lifetime
1991
- 1991-11-25 CS CS913579A patent/CS357991A3/cs unknown
1997
- 1997-07-25 NL NL970029C patent/NL970029I2/nl unknown
- 1997-07-30 LU LU90085C patent/LU90085I2/fr unknown
1998
- 1998-06-02 HK HK98104746A patent/HK1005592A1/xx not_active IP Right Cessation
2001
- 2001-10-15 NO NO2001017C patent/NO2001017I1/no unknown

Also Published As

Publication number	Publication date
CS357991A3 (en)	1992-06-17
DE3689748T2 (de)	1994-08-11
DK170594B1 (da)	1995-11-06
IE862416L (en)	1987-03-11
GR862318B (en)	1987-01-19
NL970029I2 (nl)	1998-04-01
AU582894B2 (en)	1989-04-13
AU6255286A (en)	1987-03-12
JPS6261979A (ja)	1987-03-18
NL970029I1 (nl)	1997-10-01
AR243187A1 (es)	1993-07-30
IL79992A (en)	1990-07-12
ES2001782A6 (es)	1988-06-16
NO167026B (no)	1991-06-17
KR870003100A (ko)	1987-04-15
FR2587029B1 (fr)	1987-10-30
NZ217537A (en)	1988-11-29
US4820710A (en)	1989-04-11
HUT41771A (en)	1987-05-28
PT83355A (fr)	1986-10-01
DK431586A (da)	1987-03-12
DK431586D0 (da)	1986-09-10
HU196597B (en)	1988-12-28
JPH0460596B2 (xx)	1992-09-28
DE19775081I2 (de)	2002-08-29
NO863608D0 (no)	1986-09-10
PT83355B (pt)	1989-05-12
FI87210C (fi)	1992-12-10
KR930001411B1 (ko)	1993-02-27
FR2587029A1 (fr)	1987-03-13
ATE103603T1 (de)	1994-04-15
NO2001017I1 (no)	2001-11-05
IE61607B1 (en)	1994-11-16
HK1005592A1 (en)	1999-01-15
CA1272486A (en)	1990-08-07
EP0217700A1 (fr)	1987-04-08
FI863661A0 (fi)	1986-09-10
NO863608L (no)	1987-03-12
LU90085I2 (fr)	1997-09-25
FI87210B (fi)	1992-08-31
DE3689748D1 (de)	1994-05-05
US4912219A (en)	1990-03-27
IL79992A0 (en)	1986-12-31
ZA866901B (en)	1987-04-29
FI863661A (fi)	1987-03-12
EP0217700B1 (fr)	1994-03-30

Legal Events

Date	Code	Title	Description
2006-10-09	MK1K	Patent expired

Publication	Publication Date	Title
NO169493C (no)	1992-07-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive peptid-derivater
NO168770C (no)	1992-04-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
NO170480C (no)	1992-10-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenoksyeddiksyre-derivater
NO163406C (no)	1990-05-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinolinonderivater.
NO862477D0 (no)	1986-06-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-arylimidazol-derivater.
NO864126D0 (no)	1986-10-16	Fremgangsmaate for fremstilling av terapeutisk aktive pyridon-derivater.
NO170629C (no)	1992-11-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive dikloranilin-derivater
NO172801C (no)	1993-09-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinuklidin-derivater
NO172343C (no)	1993-07-07	Analogifremgangsmaate for fremstilling av terapeutisk aktive askorbinsyrederivater
NO171638C (no)	1993-04-14	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolin-derivater
NO864425L (no)	1987-05-08	Fremgangsmaate for fremstilling av terapeutisk aktive heterocyklyl-oksoftalazinyl-eddiksyre-derivater
NO843979L (no)	1985-04-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzyl-aminoalkyl-pyrrolidinon-derivater
NO167026C (no)	1991-09-25	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
NO169014C (no)	1992-04-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive distamycinderivater
NO168355C (no)	1992-02-12	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
NO167916C (no)	1991-12-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiolaktam-n-eddiksyrederivater
NO170482C (no)	1992-10-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksamid-derivater
NO168299C (no)	1992-02-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive alkansulfonanilid-derivater
NO171592C (no)	1993-04-07	Fremgangsmaate for fremstilling av aktive cinnolin-derivater
NO170976C (no)	1993-01-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylbuten-syrederivater
NO862372D0 (no)	1986-06-13	Fremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater.
NO169069C (no)	1992-05-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-alkoksy-2-aminopropylaminderivater
NO165069C (no)	1990-12-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive cyklopentyletere.
NO173061C (no)	1993-10-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-benzotiazoliner
NO169648C (no)	1992-07-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater