NL8602914A - Nitroanthracyclines, werkwijze voor het bereiden daarvan en gebruik daarvan. - Google Patents

Nitroanthracyclines, werkwijze voor het bereiden daarvan en gebruik daarvan. Download PDF

Info

Publication number
NL8602914A
NL8602914A NL8602914A NL8602914A NL8602914A NL 8602914 A NL8602914 A NL 8602914A NL 8602914 A NL8602914 A NL 8602914A NL 8602914 A NL8602914 A NL 8602914A NL 8602914 A NL8602914 A NL 8602914A
Authority
NL
Netherlands
Prior art keywords
formula
compound
demethoxy
aglycone
pharmaceutically acceptable
Prior art date
Application number
NL8602914A
Other languages
English (en)
Dutch (nl)
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of NL8602914A publication Critical patent/NL8602914A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NL8602914A 1985-11-19 1986-11-17 Nitroanthracyclines, werkwijze voor het bereiden daarvan en gebruik daarvan. NL8602914A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8528440A GB2182926B (en) 1985-11-19 1985-11-19 Nitro anthracyclines, process for their preparation and use thereof
GB8528440 1985-11-19

Publications (1)

Publication Number Publication Date
NL8602914A true NL8602914A (nl) 1987-06-16

Family

ID=10588420

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8602914A NL8602914A (nl) 1985-11-19 1986-11-17 Nitroanthracyclines, werkwijze voor het bereiden daarvan en gebruik daarvan.

Country Status (22)

Country Link
US (1) US4749693A (el)
JP (1) JPH0778073B2 (el)
AT (1) AT390618B (el)
AU (1) AU590639B2 (el)
BE (1) BE905751A (el)
CA (1) CA1296325C (el)
DE (1) DE3638386C2 (el)
DK (1) DK548086A (el)
ES (1) ES2002909A6 (el)
FI (1) FI864566A (el)
FR (1) FR2590260B1 (el)
GB (1) GB2182926B (el)
GR (1) GR862719B (el)
HU (1) HU195667B (el)
IL (1) IL80589A0 (el)
IT (1) IT1206480B (el)
NL (1) NL8602914A (el)
NZ (1) NZ218256A (el)
PT (1) PT83757B (el)
SE (1) SE8604870L (el)
SU (1) SU1553015A3 (el)
ZA (1) ZA868700B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2591599B1 (fr) * 1985-12-17 1988-08-05 Hoechst Lab Nouvelles anthracyclines et medicaments les contenant
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
US5412081A (en) * 1989-02-07 1995-05-02 Farmitalia Carlo Erba S.R.L. New 4'-epi-4'-amino anthracyclines
IT1275953B1 (it) * 1995-03-22 1997-10-24 Sicor Spa Procedimento per la preparazione di antibiotici della classe delle antracicline
EP0971716A4 (en) * 1996-03-22 2000-01-19 Waldemar Priebe UP TO ANTHRACYCLINE WITH HIGH EFFECTIVENESS AGAINST DOXORUBICIN RESISTANT TUMORS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US4521592A (en) * 1981-10-23 1985-06-04 Svenska Sockerfabriks Ab Compounds for therapeutic or diagnostic use, a process and intermediates for their preparation
NL8300150A (nl) * 1982-01-26 1983-08-16 Erba Farmitalia Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing.
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same

Also Published As

Publication number Publication date
PT83757A (en) 1986-12-01
IT8622180A0 (it) 1986-10-29
JPS62120395A (ja) 1987-06-01
GR862719B (en) 1987-03-16
DK548086D0 (da) 1986-11-17
AU590639B2 (en) 1989-11-09
DE3638386C2 (de) 1995-09-14
NZ218256A (en) 1988-11-29
IL80589A0 (en) 1987-02-27
DK548086A (da) 1987-05-20
FI864566A (fi) 1987-05-20
ES2002909A6 (es) 1988-10-01
GB8528440D0 (en) 1985-12-24
GB2182926A (en) 1987-05-28
SU1553015A3 (ru) 1990-03-23
FR2590260A1 (fr) 1987-05-22
AT390618B (de) 1990-06-11
JPH0778073B2 (ja) 1995-08-23
BE905751A (fr) 1987-03-02
FR2590260B1 (fr) 1988-09-23
CA1296325C (en) 1992-02-25
AU6510086A (en) 1987-05-21
PT83757B (en) 1988-12-07
SE8604870L (sv) 1987-05-20
FI864566A0 (fi) 1986-11-11
DE3638386A1 (de) 1987-05-21
US4749693A (en) 1988-06-07
HUT42100A (en) 1987-06-29
IT1206480B (it) 1989-04-27
SE8604870D0 (sv) 1986-11-13
GB2182926B (en) 1989-10-04
ZA868700B (en) 1987-07-29
HU195667B (en) 1988-06-28
ATA298586A (de) 1989-11-15

Similar Documents

Publication Publication Date Title
DK170405B1 (da) Anthracyclinglycosider, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende disse samt mellemprodukter ved fremstillingen af disse
US4987126A (en) 3'-deamino-4'-deoxy-4'-amino anthracyclines
EP0051280B1 (en) Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions
IE904543A1 (en) Morpholinyl derivatives of of doxorubicin and process for¹their preparation
NL8602914A (nl) Nitroanthracyclines, werkwijze voor het bereiden daarvan en gebruik daarvan.
NL8702436A (nl) Anthracycline glycosiden met antitumorwerking, bereiding daarvan, tussenprodukten daarvoor, en preparaten alsmede gebruik daarvan.
JPS61227589A (ja) 新規アントラサイクリングリコシド類，それらの製造方法及びそれらを含む抗腫瘍剤
US4199571A (en) Substituted anthracyclines, their preparation and use
DK168597B1 (da) 4-substituerede demethoxy-daunomydinoner og anthracyclinglycosider deraf samt fremgangsmåde til fremstilling af glycosiderne
EP0354995B1 (en) 4-substituted anthracyclinones and anthracycline glycosides and their preparation
FI78109C (fi) Foerfarande foer framstaellning av antracyklinglykosider.
FI96605B (fi) Menetelmä farmaseuttisesti käyttökelpoisten 4'-epi-4'-aminoantrasykliinien valmistamiseksi sekä menetelmässä käytettävät välituotteet
SE500732C2 (sv) Nya antracyklinglykosidderivat, förfarande för framställning därav samt farmaceutiska kompositioner därav
US4563444A (en) Anthracycline glycosides, use and compositions containing same
de Peredo et al. Synthesis and biological evaluation of flavanones and flavones related to podophyllotoxin
GB2238540A (en) 13-deoxy-4'-deoxy-4'-iodoanthracyclines and intermediates therefor
NL8802721A (nl) Nieuwe 4-demethoxy antracyclinederivaten.
HU209458B (en) Process for preparing 3'-deamino-4'-deoxy-4'-amino-8-fluoranthracyclin derivatives and pharmaceutical compositions containing them as active agents
EP0207424B1 (en) Anthracyclins
FI89496B (fi) Foerfarande foer framstaellning av 4-demetoxi-4-aminoantracykliner
RU2024483C1 (ru) 4-замещенные антрациклиноны и гликозид антрациклина
GB2034707A (en) Anthracycline glycosides
DK150606B (da) Analogifremgangsmaade til fremstilling af 3',4'-diepi-4'-o-methyldaunorubicin eller 3',4'-diepi-4'-o-methyldoxorubicin, samt et beskyttet halogensukker til anvendelse ved fremgangsmaaden
JPH01311095A (ja) ４―デメトキシ―４′―デオキシ―４′―ヨードアントラサイクリングリコシド

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed