NL186812C - Op de 3-plaats van de triazoolring gesubstitueerde 1-methyl-5-(3-Ÿ3-(1-piperidinylmethyl)fenoxyŸpropyl)amino-1h-1,2,4-triazoolverbinding, en farmaceutisch preparaat met histamine hŸ2-antagonist werking. - Google Patents

Op de 3-plaats van de triazoolring gesubstitueerde 1-methyl-5-(3-Ÿ3-(1-piperidinylmethyl)fenoxyŸpropyl)amino-1h-1,2,4-triazoolverbinding, en farmaceutisch preparaat met histamine hŸ2-antagonist werking.

Info

Publication number
NL186812C
NL186812C NLAANVRAGE8100979,A NL8100979A NL186812C NL 186812 C NL186812 C NL 186812C NL 8100979 A NL8100979 A NL 8100979A NL 186812 C NL186812 C NL 186812C
Authority
NL
Netherlands
Prior art keywords
phenoxyÿpropyl
piperidinylmethyl
histamine
antagonist
amino
Prior art date
Application number
NLAANVRAGE8100979,A
Other languages
English (en)
Other versions
NL186812B (nl
NL8100979A (nl
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NL8100979A publication Critical patent/NL8100979A/nl
Publication of NL186812B publication Critical patent/NL186812B/nl
Application granted granted Critical
Publication of NL186812C publication Critical patent/NL186812C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
NLAANVRAGE8100979,A 1980-02-28 1981-02-27 Op de 3-plaats van de triazoolring gesubstitueerde 1-methyl-5-(3-Ÿ3-(1-piperidinylmethyl)fenoxyŸpropyl)amino-1h-1,2,4-triazoolverbinding, en farmaceutisch preparaat met histamine hŸ2-antagonist werking. NL186812C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8006806 1980-02-28

Publications (3)

Publication Number Publication Date
NL8100979A NL8100979A (nl) 1981-10-01
NL186812B NL186812B (nl) 1990-10-01
NL186812C true NL186812C (nl) 1991-03-01

Family

ID=10511754

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE8100979,A NL186812C (nl) 1980-02-28 1981-02-27 Op de 3-plaats van de triazoolring gesubstitueerde 1-methyl-5-(3-Ÿ3-(1-piperidinylmethyl)fenoxyŸpropyl)amino-1h-1,2,4-triazoolverbinding, en farmaceutisch preparaat met histamine hŸ2-antagonist werking.
NL8802221A NL8802221A (nl) 1980-02-28 1988-09-09 Heterocyclische verbindingen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL8802221A NL8802221A (nl) 1980-02-28 1988-09-09 Heterocyclische verbindingen.

Country Status (26)

Country Link
US (1) US4670448A (nl)
JP (2) JPS56147777A (nl)
KR (3) KR850000668B1 (nl)
AT (2) AT380240B (nl)
AU (1) AU544357B2 (nl)
BE (1) BE887730A (nl)
CA (1) CA1158649A (nl)
CH (1) CH655104A5 (nl)
CY (1) CY1335A (nl)
DE (1) DE3107628A1 (nl)
DK (1) DK90681A (nl)
ES (4) ES499931A0 (nl)
FI (1) FI76076C (nl)
FR (1) FR2477150A1 (nl)
GB (1) GB2075007B (nl)
HK (1) HK69186A (nl)
IE (1) IE50987B1 (nl)
IL (1) IL62229A (nl)
IT (1) IT1209846B (nl)
KE (1) KE3629A (nl)
MY (1) MY8500428A (nl)
NL (2) NL186812C (nl)
NO (1) NO810681L (nl)
NZ (1) NZ196365A (nl)
SE (1) SE448233B (nl)
ZA (1) ZA811331B (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57169452A (en) * 1981-04-14 1982-10-19 Teikoku Hormone Mfg Co Ltd Novel phenoxyalkylamide derivative
ES8307768A1 (es) * 1981-06-11 1983-08-01 Glaxo Group Ltd Un procedimiento para la preparacion de nuevos derivados de 1,2,4 triazol.
PT76280A (en) * 1982-02-24 1983-03-01 Glaxo Group Ltd Process for preparing heterocyclic derivatives
CA1189508A (en) * 1982-02-25 1985-06-25 Roger Hayes Heterocyclic derivatives as histamine h.sub.2- antagonists
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
GB8628475D0 (en) * 1986-11-28 1987-01-07 Glaxo Group Ltd Medicaments
GB8805268D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
JP3328082B2 (ja) * 1994-12-13 2002-09-24 日本カーバイド工業株式会社 Ｎ−グアニジノチオ尿素塩及び３−アミノ−５−メルカプト−１，２，４−トリアゾールの製造方法
JP2003510359A (ja) 1999-10-01 2003-03-18 スミスクライン・ビーチャム・コーポレイション 化合物および方法
JP4564786B2 (ja) * 2004-06-07 2010-10-20 株式会社日本ファインケム １−置換―１―アミノグアニジン又はその塩、及びこれらの製造方法
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
PT70884A (en) * 1979-03-02 1980-03-01 Glaxo Group Ltd Process for preparing heterocyclic derivatives

Also Published As

Publication number Publication date
AU544357B2 (en) 1985-05-23
US4670448A (en) 1987-06-02
KR830005164A (ko) 1983-08-03
ES8506292A1 (es) 1985-07-01
NL186812B (nl) 1990-10-01
FR2477150B1 (nl) 1984-03-16
IL62229A (en) 1987-10-30
KR850000682B1 (ko) 1985-05-14
CY1335A (en) 1986-10-24
AU6793381A (en) 1981-09-03
GB2075007A (en) 1981-11-11
IE810431L (en) 1981-08-28
FR2477150A1 (fr) 1981-09-04
JPS6452763A (en) 1989-02-28
IT8147905A0 (it) 1981-02-27
ES8205208A1 (es) 1982-06-01
ES8405775A1 (es) 1984-06-16
SE448233B (sv) 1987-02-02
NO810681L (no) 1981-08-31
ES518305A0 (es) 1984-06-16
ES509669A0 (es) 1983-03-16
HK69186A (en) 1986-09-26
ATA151084A (de) 1988-08-15
KR850000668B1 (ko) 1985-05-09
NL8802221A (nl) 1989-01-02
IE50987B1 (en) 1986-09-03
KE3629A (en) 1986-05-16
SE8101311L (sv) 1981-08-29
ZA811331B (en) 1982-10-27
AT387774B (de) 1989-03-10
JPS56147777A (en) 1981-11-16
ES499931A0 (es) 1982-06-01
DE3107628C2 (nl) 1991-03-14
JPH0338269B2 (nl) 1991-06-10
GB2075007B (en) 1983-07-13
DE3107628A1 (de) 1982-04-01
FI810619L (fi) 1981-08-29
FI76076B (fi) 1988-05-31
KR850002010A (ko) 1985-04-10
NL8100979A (nl) 1981-10-01
ES530741A0 (es) 1985-07-01
IL62229A0 (en) 1981-03-31
ATA93981A (de) 1985-09-15
CA1158649A (en) 1983-12-13
CH655104A5 (fr) 1986-03-27
AT380240B (de) 1986-04-25
DK90681A (da) 1981-08-29
NZ196365A (en) 1984-07-31
IT1209846B (it) 1989-08-30
FI76076C (fi) 1988-09-09
ES8304954A1 (es) 1983-03-16
KR850002011A (ko) 1985-04-10
KR850000676B1 (ko) 1985-05-10
MY8500428A (en) 1985-12-31
BE887730A (fr) 1981-08-27

Similar Documents

Publication Publication Date Title
IT8222308A0 (it) Trasduttore induttivo lineare.
NL990010I2 (nl) Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten.
IT8221475A0 (it) Cilindro.
ES517160A0 (es) Una acilanilida.
NL186812C (nl) Op de 3-plaats van de triazoolring gesubstitueerde 1-methyl-5-(3-Ÿ3-(1-piperidinylmethyl)fenoxyŸpropyl)amino-1h-1,2,4-triazoolverbinding, en farmaceutisch preparaat met histamine hŸ2-antagonist werking.
IT8221851A0 (it) Complesso fotoconduttivo multistrato, presentante un'eterogiunzione intermedia.
DE3679745D1 (de) 1-dimethylcarbamoyl-3-substituierte-5-substituierte-1h-1,2,4-triazole.
ATE45063T1 (de) Emulgierbare konzentrate enthaltend azole.
ES513883A0 (es) 10-(1-aza-(2,2,2)-biciclo-3-octil) 10 h-fenotiazin-2-sulfonamidas.
IT8205155A1 (it) Broccia per la lavorazione di interni.
IT8321365A0 (it) Valvola di erogazione.
ATE21010T1 (de) Fungizide.
ES509736A0 (es) Una combinacion antitranspirante.
IT8220938A0 (it) Dispositivo di pompaggio.
IT8024353A0 (it) Procedimento per la preparazione di 2,5-dimetil 2,4-esadiene.
NO824007L (no) Emballasje.
IT8219495A0 (it) Fungicidi.
IT8219496A0 (it) Fungicidi.
NO155772C (no) 1,2,4-triazolderivater.
IT8222658A0 (it) Cilindro di smerigliatura.
ES261397Y (es) Envase contenedor, perfeccionado.
ATE15804T1 (de) Fungizide 1,2,4-triazol- und imidazol-derivate.
ATE43593T1 (de) Fungizide azolylderivate.
ES261365Y (es) Bolsa perfeccionada.
ATE25526T1 (de) Polybuten-1.

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BV The patent application has lapsed
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee