NL148037B - Werkwijze voor de bereiding van farmaceutische preparaten en de door toepassing daarvan vervaardigde voorwerpen, alsmede werkwijze ter bereiding van anti-inflammatoir, analgetisch, antipyretisch en antipruritisch werkzame verbindingen. - Google Patents

Werkwijze voor de bereiding van farmaceutische preparaten en de door toepassing daarvan vervaardigde voorwerpen, alsmede werkwijze ter bereiding van anti-inflammatoir, analgetisch, antipyretisch en antipruritisch werkzame verbindingen.

Info

Publication number
NL148037B
NL148037B NL696910156A NL6910156A NL148037B NL 148037 B NL148037 B NL 148037B NL 696910156 A NL696910156 A NL 696910156A NL 6910156 A NL6910156 A NL 6910156A NL 148037 B NL148037 B NL 148037B
Authority
NL
Netherlands
Prior art keywords
antippuritic
antipyretic
analgesic
inflammatory
compounds
Prior art date
Application number
NL696910156A
Other languages
English (en)
Other versions
NL6910156A (nl
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Corp filed Critical Syntex Corp
Publication of NL6910156A publication Critical patent/NL6910156A/xx
Publication of NL148037B publication Critical patent/NL148037B/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/14—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with at least one hydroxy group on a condensed ring system containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/205—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings
    • C07C39/225—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL696910156A 1968-07-02 1969-07-02 Werkwijze voor de bereiding van farmaceutische preparaten en de door toepassing daarvan vervaardigde voorwerpen, alsmede werkwijze ter bereiding van anti-inflammatoir, analgetisch, antipyretisch en antipruritisch werkzame verbindingen. NL148037B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74190468A 1968-07-02 1968-07-02

Publications (2)

Publication Number Publication Date
NL6910156A NL6910156A (nl) 1970-01-06
NL148037B true NL148037B (nl) 1975-12-15

Family

ID=24982695

Family Applications (1)

Application Number Title Priority Date Filing Date
NL696910156A NL148037B (nl) 1968-07-02 1969-07-02 Werkwijze voor de bereiding van farmaceutische preparaten en de door toepassing daarvan vervaardigde voorwerpen, alsmede werkwijze ter bereiding van anti-inflammatoir, analgetisch, antipyretisch en antipruritisch werkzame verbindingen.

Country Status (13)

Country Link
US (1) US3641161A (nl)
JP (1) JPS5026534B1 (nl)
BE (1) BE734275A (nl)
BR (1) BR6910380D0 (nl)
CH (1) CH535730A (nl)
DE (1) DE1932389B2 (nl)
ES (1) ES368882A1 (nl)
FR (1) FR2012150B1 (nl)
GB (1) GB1271132A (nl)
HK (1) HK27076A (nl)
IL (1) IL32161A (nl)
NL (1) NL148037B (nl)
SE (1) SE366019B (nl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6915472D0 (pt) * 1969-09-30 1973-06-14 Syntex Corp Processo para preparar 2-(6-metoxi-2-naftil)-1-propanol
US3969415A (en) * 1971-12-01 1976-07-13 Sandoz, Inc. 1-(2-Naphthyl)-2,3-butadien-1-ols
US4035406A (en) * 1973-08-20 1977-07-12 Sandoz, Inc. 4-alkyl-4-naphthyl-butanes
US4194010A (en) * 1975-10-29 1980-03-18 Beecham Group Limited Pharmacologically active enol ether compounds
US4709082A (en) * 1984-10-25 1987-11-24 Nissan Chemical Industries, Ltd. 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof
US4833164A (en) * 1985-05-08 1989-05-23 E. I. Du Pont De Nemours And Company 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US4912248A (en) * 1987-05-18 1990-03-27 The Procter & Gamble Company Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation
US5093371A (en) * 1990-07-02 1992-03-03 University Of Iowa Research Foundation Naphthyl ketone inhibitors of cholesterol esterase and their use as hypolipidemic and hypocaloric agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL72794C (nl) *

Also Published As

Publication number Publication date
DE1932389C3 (nl) 1974-10-10
CH535730A (de) 1973-04-15
SE366019B (nl) 1974-04-08
FR2012150B1 (nl) 1973-08-10
DE1932389A1 (de) 1970-04-23
US3641161A (en) 1972-02-08
JPS5026534B1 (nl) 1975-09-01
DE1932389B2 (de) 1974-03-07
FR2012150A1 (nl) 1970-03-13
HK27076A (en) 1976-05-21
BR6910380D0 (pt) 1973-02-08
NL6910156A (nl) 1970-01-06
ES368882A1 (es) 1971-05-16
GB1271132A (en) 1972-04-19
IL32161A (en) 1972-12-29
BE734275A (nl) 1969-11-17
IL32161A0 (en) 1969-07-30

Similar Documents

Publication Publication Date Title
NL150680B (nl) Werkwijze ter bereiding van farmaceutische preparaten.
NL7706646A (nl) Werkwijze ter bereiding van diuretisch werkzame farmaceutische preparaten, de door toepassing daarvan verkregen gevormde voortbrengselen, als- mede werkwijze ter bereiding van diuretisch werk- zame verbindingen.
NL161759C (nl) Werkwijze ter bereiding van salicylzuurverbindingen, werkwijze ter bereiding van farmaceutische preparaten, alsmede de door toepassing daarvan verkregen gevormde voortbrengselen.
NL160485C (nl) Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire, analgetische en anti-pyretische wer- king, alsmede door toepassing van deze werkwijze verkregen voorwerpen.
NL148037B (nl) Werkwijze voor de bereiding van farmaceutische preparaten en de door toepassing daarvan vervaardigde voorwerpen, alsmede werkwijze ter bereiding van anti-inflammatoir, analgetisch, antipyretisch en antipruritisch werkzame verbindingen.
NL161451B (nl) Werkwijze voor het bereiden van een farmaceutisch prepa- raat en werkwijze voor het bereiden van een verbinding, geschikt voor gebruik bij de bereiding van dit prepa- raat.
NL160275C (nl) Werkwijze ter bereiding van farmaceutische preparaten met anti-leukemische en anti-inflammatoire werking, de door toepassing daarvan verkregen gevormde voortbrengselen en werkwijze ter bereiding van anti-leukemisch en anti-inflam- matoir werkzame verbindingen.
NL158386B (nl) Werkwijze ter bereiding van farmaceutische preparaten, de door toepassing daarvan verkregen gevormde voortbrengselen, alsmede werkwijze ter bereiding van farmacologisch werkzame 1h-1,5-benzodiazepine-2,4-dionderivaten.
NL157012B (nl) Werkwijze voor de bereiding van farmaceutische preparaten met anti-inflammatoire werking, aldus verkregen gevormde voortbrengselen, alsmede werkwijze ter bereiding van anti-inflammatoir werkzame heterocyclische verbindingen.
NL174043C (nl) Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire, analgetische en antipyretische werking, door toepassing daarvan verkregen gevormde voortbrengselen, alsmede werkwijze ter bereiding van 4-oxazolylfenylazijnzuurderivaten.
NL7512107A (nl) Werkwijze ter bereiding van farmaceutische pre- paraten met antiinflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking.
NL7500224A (nl) Werkwijze voor het bereiden van prostaglandine- oga; werkwijze ter bereiding van farmaceu- e preparaten, alsmede de door toepassing an vervaardigde voorwerpen.
NL147131B (nl) Werkwijze voor het bereiden van farmacologisch werkzame stilbeenderivaten; werkwijze ter bereiding van farmaceutische preparaten en de door toepassing daarvan verkregen gevormde voortbrengselen.
NL165740C (nl) Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire werking die as-triazinederivaten bevatten, verkregen gevormde preparaten, alsmede werk- wijze ter bereiding van de actieve as-triazine- derivaten.
NL185841C (nl) Werkwijze ter bereiding van farmaceutische preparaten en werkwijze ter bereiding van voor toepassing daarbij geschikte 5-mercaptopyridoxinederivaten.
NL164037C (nl) Werkwijze ter bereiding van 1,4-dithiino- -Ÿ2,3-cŸpyrrool-derivaten en van farmaceutische preparaten die deze derivaten bevatten.
NL166267C (nl) Werkwijze ter bereiding van farmaceutische preparaten, de onder toepassing daarvan verkregen gevormde voort- brengselen, alsmede werkwijze ter bereiding van 6,7-methyleen-20-spirox-4-en-3-onderivaten met aldoste- ron remmende werking.
NL175382C (nl) Werkwijze ter bereiding van antiflogistisch, analgetisch of antipyretisch werkzame farmaceutische preparaten, alsmede werkwijze ter bereiding van voor gebruik bij die werkwijze geschikte o-anilinofenylaceetamidederivaten.
NL175063C (nl) Werkwijze ter bereiding van 11,11-alkylideensteroiden, werkwijze ter bereiding van farmaceutische preparaten en gevormde farmaceutische preparaten.
NL168497B (nl) Werkwijze voor de bereiding van 2-(o-anilino-fenyl) ethaanderivaten, werkwijze ter bereiding van farma- ceutische preparaten, die deze verbindingen bevatten en verkregen farmaceutische preparaten.
NL144923B (nl) Werkwijze voor de bereiding van een nalfa-gesubstitueerd 2-0-methyloxytocinederivaat, werkwijze ter bereiding van farmaceutische preparaten en gevormde preparaten.
NL156320B (nl) Werkwijze voor de bereiding van benzylpenicillinederivaten, werkwijze ter bereiding van farmaceutische preparaten, alsmede de aldus verkregen gevormde voortbrengselen.
NL149372B (nl) Werkwijze voor het bereiden van farmaceutische preparaten, alsmede de door toepassing daarvan verkregen gevormde voortbrengselen.
NL162647C (nl) Werkwijze ter bereiding van anti-inflammatoir werkzame farmaceutische preparaten, de door toepassing daarvan verkregen gevormde voortbrengselen, en werkwijze ter bereiding van anti-inflammatoir werkzame fenylazijn- zuurderivaten.
NL164024C (nl) Werkwijze ter bereiding van anti-inflammatoir werkzame 1-benzylideen-indenyl-3-azijnzuurderivaten; werkwijze ter bereiding van farmaceutische preparaten, alsmede door toepassing daarvan verkregen gevormde voort- brengselen.

Legal Events

Date Code Title Description
SNR Assignments of patents or rights arising from examined patent applications

Owner name: SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED

NL80 Information provided on patent owner name for an already discontinued patent

Owner name: SYNTEX

V4 Discontinued because of reaching the maximum lifetime of a patent