MY173426A - A system for identifying presence of polynucleotides of interest from a sample - Google Patents

A system for identifying presence of polynucleotides of interest from a sample

Info

Publication number
MY173426A
MY173426A MYPI2011700155A MYPI2011700155A MY173426A MY 173426 A MY173426 A MY 173426A MY PI2011700155 A MYPI2011700155 A MY PI2011700155A MY PI2011700155 A MYPI2011700155 A MY PI2011700155A MY 173426 A MY173426 A MY 173426A
Authority
MY
Malaysia
Prior art keywords
sample
layer
operating circuit
polynucleotides
sensing platform
Prior art date
Application number
MYPI2011700155A
Inventor
Hamiza Hamzah Irni
Korakkottil Kunhi Mohd Shukri
Sidek Othman
Abd Manaf Asrulnizam
Original Assignee
Univ Sains Malaysia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Sains Malaysia filed Critical Univ Sains Malaysia
Priority to MYPI2011700155A priority Critical patent/MY173426A/en
Priority to PCT/MY2011/000244 priority patent/WO2013058646A1/en
Publication of MY173426A publication Critical patent/MY173426A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

A system for identifying presence of polynucleotides of interest from a sample comprising a sensing platform having a working electrode (102), a reference electrode (103) and a counter electrode (104) which are electrically connected to a connection port (101) and that the electrodes (102, 103, 104) have a top and a bottom layer respectively made of gold (111) and nickel (112), wherein surface of each layer of gold (111) is anchored with one or more oligonucleotide probes to readily hybridize with a substantially complementary polynucleotide in the sample; an operating circuit (105) provided with a receptive port to adaptably communicate with the sensing platform by mating with the connection port (101) and configured to measure a signal indicative of hybridization of the sensing platform; a display (108) connected to the operating circuit to acquire and show electrical readings of the operating circuit (105); wherein presence of polynucleotides of interest in the sample is identified by detecting the signal upon hybridization onto the probes; characterized in that the layer of nickel (112) is in between the layer of gold (111) and a base layer (109) made of copper (113) where the sensing platform and operating circuit are fabricated on.
MYPI2011700155A 2011-10-19 2011-10-19 A system for identifying presence of polynucleotides of interest from a sample MY173426A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MYPI2011700155A MY173426A (en) 2011-10-19 2011-10-19 A system for identifying presence of polynucleotides of interest from a sample
PCT/MY2011/000244 WO2013058646A1 (en) 2011-10-19 2011-12-15 A system for identifying presence of polynucleotides of interest from a sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI2011700155A MY173426A (en) 2011-10-19 2011-10-19 A system for identifying presence of polynucleotides of interest from a sample

Publications (1)

Publication Number Publication Date
MY173426A true MY173426A (en) 2020-01-23

Family

ID=48141152

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2011700155A MY173426A (en) 2011-10-19 2011-10-19 A system for identifying presence of polynucleotides of interest from a sample

Country Status (2)

Country Link
MY (1) MY173426A (en)
WO (1) WO2013058646A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6761816B1 (en) * 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
AU2001261145B2 (en) * 2000-05-03 2005-08-11 The United States Government, As Represented By The Department Of The Navy Biological identification system with integrated sensor chip
US20080087554A1 (en) * 2006-05-24 2008-04-17 Antara Biosciences Inc. Electrochemical detection device
JP4893829B2 (en) * 2007-08-01 2012-03-07 ニプロ株式会社 Stress measurement kit and stress measurement method

Also Published As

Publication number Publication date
WO2013058646A1 (en) 2013-04-25

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