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Application filed by Smithkline Beckman CorpfiledCriticalSmithkline Beckman Corp
Priority to MYPI89001417ApriorityCriticalpatent/MY107387A/en
Publication of MY107387ApublicationCriticalpatent/MY107387A/en
INVENTED ARE SUBSTITUTED ACRYLATE ANALOGUES OF STEROIDAL SYNTHETIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND METHODS OF USING THESE COMPOUNDS TO INHIBIT STEROID 5-(ALPHA)-REDUCTASE INCLUDING USING THESE COMPOUNDS TO REDUCE PROSTATE SIZE. ALSO INVENTED ARE INTERMEDIATES USED IN PREPARING THESE COMPOUNDS.
Novel 17a and 17b substituted acyl-3-carboxy 3,5-diene steroidal compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-a-reductase.