MXPA04001525A - Analogos de peptido -1 similar al glucagon. - Google Patents

Analogos de peptido -1 similar al glucagon.

Info

Publication number
MXPA04001525A
MXPA04001525A MXPA04001525A MXPA04001525A MXPA04001525A MX PA04001525 A MXPA04001525 A MX PA04001525A MX PA04001525 A MXPA04001525 A MX PA04001525A MX PA04001525 A MXPA04001525 A MX PA04001525A MX PA04001525 A MXPA04001525 A MX PA04001525A
Authority
MX
Mexico
Prior art keywords
glucagon
peptide
analogs
glp
compounds
Prior art date
Application number
MXPA04001525A
Other languages
English (en)
Inventor
Glaesner Wolfgang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MXPA04001525A publication Critical patent/MXPA04001525A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describe compuestos de peptido-1 de tipo glucagon GLP-1 con modificaciones en una o mas de las siguientes posiciones:7, 8, 12, 16, 18, 19, 20, 22, 25, 27, 30, 33 y 37. Se describen tambien procedimientos para el tratamiento de un sujeto que necesita la estimulacion del receptor de GLP-1 usando estos compuestos de GLP-1.
MXPA04001525A 2001-08-23 2002-08-14 Analogos de peptido -1 similar al glucagon. MXPA04001525A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31457301P 2001-08-23 2001-08-23
PCT/US2002/021325 WO2003018516A2 (en) 2001-08-23 2002-08-14 Glucagon-like peptide-1 analogs

Publications (1)

Publication Number Publication Date
MXPA04001525A true MXPA04001525A (es) 2004-05-31

Family

ID=23220481

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04001525A MXPA04001525A (es) 2001-08-23 2002-08-14 Analogos de peptido -1 similar al glucagon.

Country Status (11)

Country Link
US (1) US7101843B2 (es)
EP (1) EP1432730A4 (es)
JP (1) JP4227894B2 (es)
KR (1) KR100593348B1 (es)
AU (1) AU2002322403A1 (es)
BR (1) BR0212080A (es)
CA (1) CA2458371A1 (es)
HU (1) HUP0501192A3 (es)
IL (1) IL160493A0 (es)
MX (1) MXPA04001525A (es)
WO (1) WO2003018516A2 (es)

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Also Published As

Publication number Publication date
HUP0501192A2 (en) 2006-03-28
JP4227894B2 (ja) 2009-02-18
JP2005528321A (ja) 2005-09-22
CA2458371A1 (en) 2003-03-06
WO2003018516A2 (en) 2003-03-06
BR0212080A (pt) 2006-04-04
EP1432730A4 (en) 2006-10-11
EP1432730A2 (en) 2004-06-30
HUP0501192A3 (en) 2006-06-28
US7101843B2 (en) 2006-09-05
IL160493A0 (en) 2004-07-25
AU2002322403A1 (en) 2003-03-10
KR20040039302A (ko) 2004-05-10
KR100593348B1 (ko) 2006-06-26
US20040198654A1 (en) 2004-10-07
WO2003018516A3 (en) 2004-02-26

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