MX2021015290A - Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3). - Google Patents

Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).

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Publication number
MX2021015290A
MX2021015290A MX2021015290A MX2021015290A MX2021015290A MX 2021015290 A MX2021015290 A MX 2021015290A MX 2021015290 A MX2021015290 A MX 2021015290A MX 2021015290 A MX2021015290 A MX 2021015290A MX 2021015290 A MX2021015290 A MX 2021015290A
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MX
Mexico
Prior art keywords
apoc3
methods
expression
apolipoprotein
genes
Prior art date
Application number
MX2021015290A
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English (en)
Inventor
Kevin Fitzgerald
Stuart Milstein
Brian Bettencourt
Martin Maier
Satya Kuchimanchi
Tuyen Nguyen
Klaus Charisse
Kallanthottathil Rajeev
Muthiah Manoharan
Original Assignee
Alnylam Pharmaceuticals Inc
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Publication date
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of MX2021015290A publication Critical patent/MX2021015290A/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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Abstract

La invención se relaciona con un ácido ribonucleico de doble hebra (ARNds) dirigido a un gen para APOC3, y métodos de uso del ARNds para inhibir la expresión de APOC3.
MX2021015290A 2011-06-21 2013-12-06 Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3). MX2021015290A (es)

Applications Claiming Priority (1)

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US201161499620P 2011-06-21 2011-06-21

Publications (1)

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MX2021015290A true MX2021015290A (es) 2022-01-18

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Family Applications (2)

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MX2013014378A MX344807B (es) 2011-06-21 2012-06-21 Composiciones y metodos para inhibicion de genes para alipoproteina c-iii (apoc3).
MX2021015290A MX2021015290A (es) 2011-06-21 2013-12-06 Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).

Family Applications Before (1)

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MX2013014378A MX344807B (es) 2011-06-21 2012-06-21 Composiciones y metodos para inhibicion de genes para alipoproteina c-iii (apoc3).

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US (6) US9315813B2 (es)
EP (2) EP2723756B1 (es)
JP (5) JP6236385B2 (es)
KR (4) KR102540778B1 (es)
CN (3) CN107201364A (es)
AU (6) AU2012272860A1 (es)
BR (1) BR112013032645A2 (es)
CA (2) CA2839711C (es)
MX (2) MX344807B (es)
RU (1) RU2631805C2 (es)
WO (1) WO2012177947A2 (es)

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