MX2016012278A - Deteccion temprana de preeclampsia. - Google Patents

Deteccion temprana de preeclampsia.

Info

Publication number
MX2016012278A
MX2016012278A MX2016012278A MX2016012278A MX2016012278A MX 2016012278 A MX2016012278 A MX 2016012278A MX 2016012278 A MX2016012278 A MX 2016012278A MX 2016012278 A MX2016012278 A MX 2016012278A MX 2016012278 A MX2016012278 A MX 2016012278A
Authority
MX
Mexico
Prior art keywords
preeclampsia
subject
early detection
anxa2
level
Prior art date
Application number
MX2016012278A
Other languages
English (en)
Inventor
Simon Carlos
GARRIDO Tamara
Pellicer Antonio
Original Assignee
Igenomix S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Igenomix S L filed Critical Igenomix S L
Publication of MX2016012278A publication Critical patent/MX2016012278A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La invención proporciona ensayos no invasivos para identificar de manera confiable mujeres que tienen o están predispuestas a desarrollar preclampsia (PE); el método comprende medir un nivel de anexina A2 (ANXA2) en una muestra de prueba obtenida de un sujeto; e identificar al sujeto que tiene preclampsia o tiene un riesgo elevado de desarrollar preclampsia cuando el nivel de ANXA2 en la muestra de prueba disminuye con relación a una muestra de control; también se proporcionan métodos para tratar a un sujeto que se ha identificado que tiene PE o está en un riesgo elevado de desarrollar preclampsia.
MX2016012278A 2014-03-21 2015-03-19 Deteccion temprana de preeclampsia. MX2016012278A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461968728P 2014-03-21 2014-03-21
US201461969520P 2014-03-24 2014-03-24
PCT/IB2015/001404 WO2015166353A2 (en) 2014-03-21 2015-03-19 Early detection of preeclampsia

Publications (1)

Publication Number Publication Date
MX2016012278A true MX2016012278A (es) 2017-04-27

Family

ID=54147245

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016012278A MX2016012278A (es) 2014-03-21 2015-03-19 Deteccion temprana de preeclampsia.

Country Status (8)

Country Link
US (1) US20170097358A1 (es)
EP (1) EP3120152A2 (es)
JP (1) JP6684263B2 (es)
CN (2) CN106662589B (es)
BR (1) BR112016021630A2 (es)
CA (1) CA2943284A1 (es)
MX (1) MX2016012278A (es)
WO (1) WO2015166353A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010010201A1 (es) 2008-07-22 2010-01-28 Equipo Ivi Investigacion Sl Perfil de expresion genetica como marcador de la receptividad endometrial
WO2015193737A1 (en) 2014-06-17 2015-12-23 Igenomix S.L. Stem cell therapy in endometrial pathologies
WO2019048927A2 (en) * 2017-09-05 2019-03-14 Igenomix S.L. METHODS AND DEVICES FOR DETECTION OF BIOMARKERS ASSOCIATED WITH PRECLAMPSIA
WO2019173418A1 (en) * 2018-03-06 2019-09-12 The Feinstein Institute For Medical Research Methods for detecting and treating endometriosis
CN114990038B (zh) * 2022-05-24 2023-06-27 郑州大学 一种细菌外膜囊泡及其在制备先兆子痫治疗药物中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712103A (en) * 1995-02-13 1998-01-27 Regents Of The University Of California Diagnostic assay for the prediction of preeclampsia
IL127896A0 (en) * 1998-12-31 1999-10-28 Gail Laster A novel treatment for preeclampsia and related diseases
WO2007030889A1 (en) * 2005-09-15 2007-03-22 Victor Voroteliak Method of diagnosing pre-eclampsia
EP2147309A4 (en) * 2007-05-05 2010-08-04 Univ Western Ontario METHODS OF DETECTING PRECLAMPSY
EP2019318A1 (en) * 2007-07-27 2009-01-28 Erasmus University Medical Center Rotterdam Protein markers for cardiovascular events
CN101290321A (zh) * 2008-04-11 2008-10-22 中国医学科学院肿瘤研究所 膜联蛋白a2的血清检测方法、检测试剂盒及其应用
WO2009143633A1 (en) 2008-05-30 2009-12-03 Institut De Recherches Cliniques De Montreal Pcsk9 inhibitors and methods of use thereof
CN110187119B (zh) * 2008-10-31 2022-07-29 耶鲁大学 子痫前期检测和治疗的方法和组合物
US20120107825A1 (en) * 2010-11-01 2012-05-03 Winger Edward E Methods and compositions for assessing patients with reproductive failure using immune cell-derived microrna
JP2014507160A (ja) * 2011-02-22 2014-03-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス．アー．エール．エル． 循環バイオマーカー
KR102200063B1 (ko) * 2011-11-30 2021-01-07 에이전시 포 사이언스, 테크놀로지 앤드 리서치 생물학적 모니터링을 위한 ｇｍ1 갱글리오사이드와 아넥신 ⅴ 마이크로입자 폴리펩타이드 비율
WO2014001244A1 (en) * 2012-06-27 2014-01-03 Roche Diagnostics Gmbh MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD
CN103436552A (zh) * 2013-09-10 2013-12-11 浙江大学 一种人源annexin A2的生产方法及其应用

Also Published As

Publication number Publication date
CN106662589A (zh) 2017-05-10
CN106662589B (zh) 2019-07-30
CN110927385A (zh) 2020-03-27
US20170097358A1 (en) 2017-04-06
EP3120152A2 (en) 2017-01-25
JP2017513021A (ja) 2017-05-25
WO2015166353A3 (en) 2016-01-21
WO2015166353A2 (en) 2015-11-05
CA2943284A1 (en) 2015-11-05
BR112016021630A2 (pt) 2020-02-27
JP6684263B2 (ja) 2020-04-22

Similar Documents

Publication Publication Date Title
MX2021006791A (es) Metodos y composiciones para detectar proteinas mal plegadas.
MX2018008421A (es) Métodos para tratar cáncer y el uso de biomarcadores como predictor de sensibilidad clínica a terapias.
AR095363A1 (es) Biomarcadores y métodos para el tratamiento de condiciones relacionadas con pd-1 y pd-l1
BR112016027475A2 (pt) kit, dispositivo e método para a detecção de câncer pancreático
MX2016013261A (es) Metodo para la cuantificacion de huevos de parasitos en las heces.
EP3800253A3 (en) Prostate cancer detection kit or device, and detection method
EP3816303A3 (en) Breast cancer detection kit or device, and method for detecting breast cancer
WO2015094995A3 (en) Gene signature biomarkers of tumor response to pd-1 antagonists
BR112016019836A2 (pt) método para analisar uma amostra de um sujeito, dispositivo de diagnóstico para utilização no diagnóstico da endometriose, kit, uso de um biomarcador, e, método para aumentar uma resposta de anticorpos em um sujeito
WO2015094996A3 (en) Pd-l1 gene signature biomarkers of tumor response to pd-1 antagonists
WO2015131151A3 (en) Method and apparatus for determining markers of health by analysis of blood
MX2016012278A (es) Deteccion temprana de preeclampsia.
MX2016001719A (es) Metodos y equipos para predecir el riesgo de tener una enfermedad o evento cardiovascular.
NZ729773A (en) Biomarkers for disease progression in melanoma
MX2019003569A (es) Metodos para tratar el cancer con bavituximab en funcion de niveles de b2 glucoproteina 1 y ensayos de estos.
IN2015DN01501A (es)
EP2937421A3 (en) Biomarker for predicting effect of an anti-C-met antibody
WO2015189591A3 (en) Method and arrays for use in diagnosing early breast cancer
GB201206323D0 (en) Methods and arrays for use in the same
SG10201806729VA (en) Novel assay to detect human periostin
MX2015013993A (es) Procedimientos y series para su uso en los mismos.
MX363679B (es) Metodo para diagnosticar cancer.
NZ720608A (en) Β-glucan assay methods
EP4400600A3 (en) Methods for detecting multiple nucleic acids in a sample
MX2018015140A (es) Firmas de biomarcadores de lupus eritematoso sistemico y sus usos.