MX2014015830A - Anticuerpos lsr y usos de los mismos para el tratamiento de cancer. - Google Patents

Anticuerpos lsr y usos de los mismos para el tratamiento de cancer.

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Publication number
MX2014015830A
MX2014015830A MX2014015830A MX2014015830A MX2014015830A MX 2014015830 A MX2014015830 A MX 2014015830A MX 2014015830 A MX2014015830 A MX 2014015830A MX 2014015830 A MX2014015830 A MX 2014015830A MX 2014015830 A MX2014015830 A MX 2014015830A
Authority
MX
Mexico
Prior art keywords
treatment
cancer
lsr antibodies
antibodies
lsr
Prior art date
Application number
MX2014015830A
Other languages
English (en)
Inventor
Liat Dassa
Zurit Levine
Ofer Levy
Galit Rotman
Gady S Cojocaru
Andrew Pow
Shirley Sameach-Greenwald
Original Assignee
Compugen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Ltd filed Critical Compugen Ltd
Publication of MX2014015830A publication Critical patent/MX2014015830A/es

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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

La invención se refiere a anticuerpos y fragmentos de unión a antígeno y conjugados que contienen los mismos y/o esqueletos alternativos, específicos para moléculas de LSR, que son fármacos adecuados para inmunoterapia y tratamiento de cáncer específico.
MX2014015830A 2012-06-21 2013-06-19 Anticuerpos lsr y usos de los mismos para el tratamiento de cancer. MX2014015830A (es)

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PCT/IL2013/050527 WO2013190555A1 (en) 2012-06-21 2013-06-19 Lsr antibodies, and uses thereof for treatment of cancer

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SG10201704992SA (en) 2017-07-28
AU2013278843A1 (en) 2014-03-27
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EP2744830A1 (en) 2014-06-25
WO2013190555A1 (en) 2013-12-27
KR20150023811A (ko) 2015-03-05
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BR112014017645A2 (pt) 2017-06-27
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