MX2011000281A - Fibrinogeno recombinante. - Google Patents
Fibrinogeno recombinante.Info
- Publication number
- MX2011000281A MX2011000281A MX2011000281A MX2011000281A MX2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A
- Authority
- MX
- Mexico
- Prior art keywords
- recombinant fibrinogen
- cell culture
- fibrinogen
- eukaryotic cell
- culture system
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se relaciona con secuencias nucleotídicas que codifican para una cadena de alfa, beta o gamma de fibrinógeno. Las secuencias se optimizan para expresión en un sistema de cultivo de células eucariotas. Estas secuencias nucleotídicas optimizadas permiten la expresión eficiente de fibrinógeno recombinante y sus variantes, en forma intacta en sistema de cultivo de células eucariotas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08159999 | 2008-07-09 | ||
PCT/EP2009/058754 WO2010004004A1 (en) | 2008-07-09 | 2009-07-09 | Recombinant fibrinogen |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011000281A true MX2011000281A (es) | 2011-04-26 |
Family
ID=39768512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011000281A MX2011000281A (es) | 2008-07-09 | 2009-07-09 | Fibrinogeno recombinante. |
Country Status (15)
Country | Link |
---|---|
US (2) | US20110177524A1 (es) |
EP (2) | EP2310411B2 (es) |
JP (1) | JP5819725B2 (es) |
KR (1) | KR20110040895A (es) |
CN (1) | CN102089322B (es) |
AU (1) | AU2009268052B2 (es) |
BR (1) | BRPI0915574A2 (es) |
CA (1) | CA2730030C (es) |
ES (1) | ES2585246T3 (es) |
HK (1) | HK1151184A1 (es) |
IL (1) | IL210495A (es) |
MX (1) | MX2011000281A (es) |
NZ (1) | NZ590871A (es) |
PL (1) | PL2310411T3 (es) |
WO (1) | WO2010004004A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5960606B2 (ja) * | 2010-01-08 | 2016-08-02 | プロフィブリックス ビーブイ | 伸長α鎖を有するフィブリノーゲンが濃縮されたフィブリノーゲン調製物 |
CA2811493C (en) * | 2010-09-15 | 2020-06-16 | Spinomix S.A. | Method for separating target molecules or particles from fibrinogen-containing samples including blood components |
RU2013155713A (ru) | 2011-07-06 | 2015-08-20 | Профибрикс Бв | Составы для лечения ран |
EP2556842A1 (en) | 2011-08-11 | 2013-02-13 | Bioftalmik, S.L. | Composition in the form of film comprising fibrinogen and a fibrinogen activator and the applications thereof |
FR2981661B1 (fr) * | 2011-10-25 | 2015-06-19 | Lfb Biotechnologies | Procede de preparation du facteur h humain |
US10208101B2 (en) | 2013-12-27 | 2019-02-19 | Japan Blood Products Organization | Recombinant fibrinogen high-production line and method for producing same |
IL231230A0 (en) * | 2014-02-27 | 2014-08-31 | Omrix Biopharmaceuticals Ltd | Fibrinogen preparation |
EP3270950B1 (en) * | 2015-03-20 | 2021-04-21 | Université de Paris | Isolated peptides and fragments thereof from fibrinogen for use as drugs, particularly in skin inflammatory diseases |
DK3618853T3 (da) * | 2018-04-24 | 2020-11-30 | Fibriant B V | Fibrinogen-gamma-prime-varianter til anvendelse til behandling af en infektion |
CN114615991A (zh) | 2019-10-23 | 2022-06-10 | 菲布赖恩特公司 | 作为用于抗微生物剂的佐剂的纤维蛋白原和疗法 |
WO2023222770A1 (en) | 2022-05-17 | 2023-11-23 | Julius-Maximilians-Universitaet Wuerzburg | Novel recombinant fibrinogen variants for fibrin sealants for surgical wound care |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5639940A (en) * | 1994-03-03 | 1997-06-17 | Pharmaceutical Proteins Ltd. | Production of fibrinogen in transgenic animals |
US6492508B1 (en) * | 1996-06-03 | 2002-12-10 | United States Surgical Corp. A Division Of Tyco Healthcare Group | Nucleic acids encoding extracellular matrix proteins |
US6037457A (en) * | 1997-01-31 | 2000-03-14 | The University Of North Carolina At Chapel Hill | Method for recombinant fibrinogen production |
JP2003502047A (ja) | 1999-06-16 | 2003-01-21 | ブリストル−マイヤーズ スクイブ カンパニー | 遺伝子治療のためのトランスフェクション/形質転換ビヒクルとしてのフィブリンシーラント |
US7304208B2 (en) * | 2000-05-02 | 2007-12-04 | Ventria Bioscience | Expression of human serum albumin (HSA) in monocot seeds |
NL1020426C2 (nl) | 2002-04-18 | 2003-10-21 | Tno | Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. |
AU2003218396B2 (en) * | 2003-04-11 | 2008-09-04 | Ventria Bioscience | Human blood proteins expressed in monocot seeds |
EP2806027B1 (en) * | 2003-07-29 | 2017-05-10 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Process for producing recombinant fibrinogen highly producing cell and highly producing cell |
WO2005116235A2 (en) * | 2004-05-07 | 2005-12-08 | The Regents Of The University Of California | Endothelial cell apoptosis induced by fibrinogen gamma chain c-terminal fragment |
WO2006125021A2 (en) * | 2005-05-16 | 2006-11-23 | Dana Farber Cancer Institute, Inc. | Fibrinogen alpha and hemoglobin polypeptides as cancer markers |
KR101273829B1 (ko) * | 2005-05-20 | 2013-06-11 | 론자 바이올로직스 피엘씨 | 포유류 숙주 세포에서의 재조합 항체의 고-수준 발현 |
CA2644926A1 (en) * | 2006-03-06 | 2007-09-13 | Humagene, Inc. | A method for the preparation of recombinant human thrombin and fibrinogen |
-
2009
- 2009-07-09 AU AU2009268052A patent/AU2009268052B2/en not_active Ceased
- 2009-07-09 PL PL09793957T patent/PL2310411T3/pl unknown
- 2009-07-09 EP EP09793957.3A patent/EP2310411B2/en not_active Not-in-force
- 2009-07-09 KR KR1020117003048A patent/KR20110040895A/ko active IP Right Grant
- 2009-07-09 CA CA2730030A patent/CA2730030C/en not_active Expired - Fee Related
- 2009-07-09 WO PCT/EP2009/058754 patent/WO2010004004A1/en active Application Filing
- 2009-07-09 JP JP2011517161A patent/JP5819725B2/ja not_active Expired - Fee Related
- 2009-07-09 ES ES09793957.3T patent/ES2585246T3/es active Active
- 2009-07-09 MX MX2011000281A patent/MX2011000281A/es active IP Right Grant
- 2009-07-09 BR BRPI0915574A patent/BRPI0915574A2/pt not_active Application Discontinuation
- 2009-07-09 CN CN200980126952.5A patent/CN102089322B/zh not_active Expired - Fee Related
- 2009-07-09 NZ NZ590871A patent/NZ590871A/en not_active IP Right Cessation
- 2009-07-09 EP EP16168954.2A patent/EP3078673A3/en not_active Withdrawn
- 2009-07-09 US US13/002,797 patent/US20110177524A1/en not_active Abandoned
-
2011
- 2011-01-06 IL IL210495A patent/IL210495A/en not_active IP Right Cessation
- 2011-06-24 HK HK11106555.1A patent/HK1151184A1/zh not_active IP Right Cessation
-
2016
- 2016-10-24 US US15/331,942 patent/US10562956B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2730030C (en) | 2019-09-03 |
CA2730030A1 (en) | 2010-01-14 |
ES2585246T3 (es) | 2016-10-04 |
AU2009268052B2 (en) | 2015-05-28 |
CN102089322A (zh) | 2011-06-08 |
HK1151184A1 (zh) | 2012-01-13 |
US20110177524A1 (en) | 2011-07-21 |
EP2310411A1 (en) | 2011-04-20 |
CN102089322B (zh) | 2015-09-23 |
EP3078673A2 (en) | 2016-10-12 |
AU2009268052A1 (en) | 2010-01-14 |
US10562956B2 (en) | 2020-02-18 |
JP2011527190A (ja) | 2011-10-27 |
BRPI0915574A2 (pt) | 2016-07-26 |
KR20110040895A (ko) | 2011-04-20 |
EP3078673A3 (en) | 2017-02-22 |
NZ590871A (en) | 2012-07-27 |
IL210495A0 (en) | 2011-03-31 |
WO2010004004A1 (en) | 2010-01-14 |
IL210495A (en) | 2016-02-29 |
EP2310411B1 (en) | 2016-05-11 |
US20170037108A1 (en) | 2017-02-09 |
JP5819725B2 (ja) | 2015-11-24 |
PL2310411T3 (pl) | 2017-02-28 |
EP2310411B2 (en) | 2019-03-20 |
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Legal Events
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FG | Grant or registration |