MX2011000281A - Fibrinogeno recombinante. - Google Patents

Fibrinogeno recombinante.

Info

Publication number
MX2011000281A
MX2011000281A MX2011000281A MX2011000281A MX2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A
Authority
MX
Mexico
Prior art keywords
recombinant fibrinogen
cell culture
fibrinogen
eukaryotic cell
culture system
Prior art date
Application number
MX2011000281A
Other languages
English (en)
Inventor
Abraham Bout
Joseph Grimbergen
Jacob Koopman
Original Assignee
Profibrix Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39768512&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011000281(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Profibrix Bv filed Critical Profibrix Bv
Publication of MX2011000281A publication Critical patent/MX2011000281A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se relaciona con secuencias nucleotídicas que codifican para una cadena de alfa, beta o gamma de fibrinógeno. Las secuencias se optimizan para expresión en un sistema de cultivo de células eucariotas. Estas secuencias nucleotídicas optimizadas permiten la expresión eficiente de fibrinógeno recombinante y sus variantes, en forma intacta en sistema de cultivo de células eucariotas.
MX2011000281A 2008-07-09 2009-07-09 Fibrinogeno recombinante. MX2011000281A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08159999 2008-07-09
PCT/EP2009/058754 WO2010004004A1 (en) 2008-07-09 2009-07-09 Recombinant fibrinogen

Publications (1)

Publication Number Publication Date
MX2011000281A true MX2011000281A (es) 2011-04-26

Family

ID=39768512

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011000281A MX2011000281A (es) 2008-07-09 2009-07-09 Fibrinogeno recombinante.

Country Status (15)

Country Link
US (2) US20110177524A1 (es)
EP (2) EP2310411B2 (es)
JP (1) JP5819725B2 (es)
KR (1) KR20110040895A (es)
CN (1) CN102089322B (es)
AU (1) AU2009268052B2 (es)
BR (1) BRPI0915574A2 (es)
CA (1) CA2730030C (es)
ES (1) ES2585246T3 (es)
HK (1) HK1151184A1 (es)
IL (1) IL210495A (es)
MX (1) MX2011000281A (es)
NZ (1) NZ590871A (es)
PL (1) PL2310411T3 (es)
WO (1) WO2010004004A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5960606B2 (ja) * 2010-01-08 2016-08-02 プロフィブリックス ビーブイ 伸長α鎖を有するフィブリノーゲンが濃縮されたフィブリノーゲン調製物
CA2811493C (en) * 2010-09-15 2020-06-16 Spinomix S.A. Method for separating target molecules or particles from fibrinogen-containing samples including blood components
RU2013155713A (ru) 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
EP2556842A1 (en) 2011-08-11 2013-02-13 Bioftalmik, S.L. Composition in the form of film comprising fibrinogen and a fibrinogen activator and the applications thereof
FR2981661B1 (fr) * 2011-10-25 2015-06-19 Lfb Biotechnologies Procede de preparation du facteur h humain
US10208101B2 (en) 2013-12-27 2019-02-19 Japan Blood Products Organization Recombinant fibrinogen high-production line and method for producing same
IL231230A0 (en) * 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen preparation
EP3270950B1 (en) * 2015-03-20 2021-04-21 Université de Paris Isolated peptides and fragments thereof from fibrinogen for use as drugs, particularly in skin inflammatory diseases
DK3618853T3 (da) * 2018-04-24 2020-11-30 Fibriant B V Fibrinogen-gamma-prime-varianter til anvendelse til behandling af en infektion
CN114615991A (zh) 2019-10-23 2022-06-10 菲布赖恩特公司 作为用于抗微生物剂的佐剂的纤维蛋白原和疗法
WO2023222770A1 (en) 2022-05-17 2023-11-23 Julius-Maximilians-Universitaet Wuerzburg Novel recombinant fibrinogen variants for fibrin sealants for surgical wound care

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639940A (en) * 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
US6492508B1 (en) * 1996-06-03 2002-12-10 United States Surgical Corp. A Division Of Tyco Healthcare Group Nucleic acids encoding extracellular matrix proteins
US6037457A (en) * 1997-01-31 2000-03-14 The University Of North Carolina At Chapel Hill Method for recombinant fibrinogen production
JP2003502047A (ja) 1999-06-16 2003-01-21 ブリストル−マイヤーズ スクイブ カンパニー 遺伝子治療のためのトランスフェクション/形質転換ビヒクルとしてのフィブリンシーラント
US7304208B2 (en) * 2000-05-02 2007-12-04 Ventria Bioscience Expression of human serum albumin (HSA) in monocot seeds
NL1020426C2 (nl) 2002-04-18 2003-10-21 Tno Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen.
AU2003218396B2 (en) * 2003-04-11 2008-09-04 Ventria Bioscience Human blood proteins expressed in monocot seeds
EP2806027B1 (en) * 2003-07-29 2017-05-10 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Process for producing recombinant fibrinogen highly producing cell and highly producing cell
WO2005116235A2 (en) * 2004-05-07 2005-12-08 The Regents Of The University Of California Endothelial cell apoptosis induced by fibrinogen gamma chain c-terminal fragment
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers
KR101273829B1 (ko) * 2005-05-20 2013-06-11 론자 바이올로직스 피엘씨 포유류 숙주 세포에서의 재조합 항체의 고-수준 발현
CA2644926A1 (en) * 2006-03-06 2007-09-13 Humagene, Inc. A method for the preparation of recombinant human thrombin and fibrinogen

Also Published As

Publication number Publication date
CA2730030C (en) 2019-09-03
CA2730030A1 (en) 2010-01-14
ES2585246T3 (es) 2016-10-04
AU2009268052B2 (en) 2015-05-28
CN102089322A (zh) 2011-06-08
HK1151184A1 (zh) 2012-01-13
US20110177524A1 (en) 2011-07-21
EP2310411A1 (en) 2011-04-20
CN102089322B (zh) 2015-09-23
EP3078673A2 (en) 2016-10-12
AU2009268052A1 (en) 2010-01-14
US10562956B2 (en) 2020-02-18
JP2011527190A (ja) 2011-10-27
BRPI0915574A2 (pt) 2016-07-26
KR20110040895A (ko) 2011-04-20
EP3078673A3 (en) 2017-02-22
NZ590871A (en) 2012-07-27
IL210495A0 (en) 2011-03-31
WO2010004004A1 (en) 2010-01-14
IL210495A (en) 2016-02-29
EP2310411B1 (en) 2016-05-11
US20170037108A1 (en) 2017-02-09
JP5819725B2 (ja) 2015-11-24
PL2310411T3 (pl) 2017-02-28
EP2310411B2 (en) 2019-03-20

Similar Documents

Publication Publication Date Title
MX2011000281A (es) Fibrinogeno recombinante.
IN2012DN00801A (es)
BRPI1011934A8 (pt) Composição
AR056256A1 (es) Plantas resistentes al estres
MX2010000348A (es) Cultivo de celulas madre pluripotentes individuales.
WO2010141801A3 (en) Reprogramming t cells and hematophietic cells
NZ599774A (en) Melanocortin-1 receptor-specific cyclic peptides
IN2012DN00338A (es)
MX2010004674A (es) Variantes de alfa-amilasa con propiedades alteradas.
MX307871B (es) Hidrolisis de almidon utilizando fitasa con una alfa amilasa.
MX2013003681A (es) Ácidos nucleicos manipulados y métodos de uso de los mismos.
WO2009149956A3 (en) Fusion protein and use thereof
MX2011011402A (es) Sistemas, metodos y composiciones para optimizar injertos enriquecidos con celulas y tejidos.
MX2010008099A (es) Anticuerpos y angiopoyetina-2 estabilizados y sus usos.
WO2012024573A3 (en) Compositions comrpising perivascular stem cells and nell-1 protein
WO2011071476A3 (en) Compositions and methods for engineering cells
MX2011013117A (es) Peptidos especificos del receptor de melanocortina.
IN2014CN01706A (es)
MX351175B (es) Detergente líquido para lavar vajillas estable al almacenamiento que contiene proteasa y amilasa.
EP2516624A4 (en) CELL LINE 3M
EA201390592A1 (ru) Аллели 1-d-дезоксиксилулозо-5-фосфат синтазы, ответственные за усиленный биосинтез терпенов
BRPI0919696A2 (pt) Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.
MY161268A (en) PEPTIDE OR PEPTIDE COMPLEX BINDING TO α2 INTEGRIN AND METHODS AND USES INVOLVING THE SAME
MX2020005724A (es) Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
MX2009004493A (es) Metodo para modificar la arquitectura de vegetales y mejorar la biomasa de los vegetales y/o el rendimiento de sacarosa.

Legal Events

Date Code Title Description
FG Grant or registration