MX2011000281A - Fibrinogeno recombinante. - Google Patents

Fibrinogeno recombinante.

Info

Publication number
MX2011000281A
MX2011000281A MX2011000281A MX2011000281A MX2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A MX 2011000281 A MX2011000281 A MX 2011000281A
Authority
MX
Mexico
Prior art keywords
recombinant fibrinogen
cell culture
fibrinogen
eukaryotic cell
culture system
Prior art date
Application number
MX2011000281A
Other languages
English (en)
Inventor
Abraham Bout
Joseph Grimbergen
Jacob Koopman
Original Assignee
Profibrix Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39768512&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011000281(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Profibrix Bv filed Critical Profibrix Bv
Publication of MX2011000281A publication Critical patent/MX2011000281A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se relaciona con secuencias nucleotídicas que codifican para una cadena de alfa, beta o gamma de fibrinógeno. Las secuencias se optimizan para expresión en un sistema de cultivo de células eucariotas. Estas secuencias nucleotídicas optimizadas permiten la expresión eficiente de fibrinógeno recombinante y sus variantes, en forma intacta en sistema de cultivo de células eucariotas.
MX2011000281A 2008-07-09 2009-07-09 Fibrinogeno recombinante. MX2011000281A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08159999 2008-07-09
PCT/EP2009/058754 WO2010004004A1 (en) 2008-07-09 2009-07-09 Recombinant fibrinogen

Publications (1)

Publication Number Publication Date
MX2011000281A true MX2011000281A (es) 2011-04-26

Family

ID=39768512

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011000281A MX2011000281A (es) 2008-07-09 2009-07-09 Fibrinogeno recombinante.

Country Status (15)

Country Link
US (2) US20110177524A1 (es)
EP (2) EP3078673A3 (es)
JP (1) JP5819725B2 (es)
KR (1) KR20110040895A (es)
CN (1) CN102089322B (es)
AU (1) AU2009268052B2 (es)
BR (1) BRPI0915574A2 (es)
CA (1) CA2730030C (es)
ES (1) ES2585246T3 (es)
HK (1) HK1151184A1 (es)
IL (1) IL210495A (es)
MX (1) MX2011000281A (es)
NZ (1) NZ590871A (es)
PL (1) PL2310411T3 (es)
WO (1) WO2010004004A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011204557B2 (en) * 2010-01-08 2014-08-28 Mallinckrodt Pharma Ip Trading D.A.C. Fibrinogen preparations enriched in fibrinogen with an extended alpha chain
PL3067431T3 (pl) * 2010-09-15 2019-12-31 Debiopharm International S.A. Urządzenie zawierające składniki krwi do oddzielania z próbek docelowych cząsteczek lub cząstek
RU2013155713A (ru) 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
EP2556842A1 (en) 2011-08-11 2013-02-13 Bioftalmik, S.L. Composition in the form of film comprising fibrinogen and a fibrinogen activator and the applications thereof
FR2981661B1 (fr) * 2011-10-25 2015-06-19 Lfb Biotechnologies Procede de preparation du facteur h humain
EP3088513B1 (en) 2013-12-27 2019-02-06 Japan Blood Products Organization Recombinant fibrinogen high-production line and method for producing same
IL231230A0 (en) * 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen preparation
DK3270950T3 (da) * 2015-03-20 2021-06-07 Univ Paris Isolerede peptider og fragmenter deraf fra fibrinogen til anvendelse som lægemidler, især ved inflammatoriske hudsygdomme
CN112105377A (zh) * 2018-04-24 2020-12-18 菲布赖恩特公司 血纤维蛋白原γ初始变体的治疗性用途
US20240115773A1 (en) 2019-10-23 2024-04-11 Fibriant B.V. Fibrinogen as adjuvant for antimicrobial agents and therapy
WO2023222770A1 (en) 2022-05-17 2023-11-23 Julius-Maximilians-Universitaet Wuerzburg Novel recombinant fibrinogen variants for fibrin sealants for surgical wound care

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639940A (en) * 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
US6492508B1 (en) * 1996-06-03 2002-12-10 United States Surgical Corp. A Division Of Tyco Healthcare Group Nucleic acids encoding extracellular matrix proteins
US6037457A (en) 1997-01-31 2000-03-14 The University Of North Carolina At Chapel Hill Method for recombinant fibrinogen production
JP2003502047A (ja) 1999-06-16 2003-01-21 ブリストル−マイヤーズ スクイブ カンパニー 遺伝子治療のためのトランスフェクション／形質転換ビヒクルとしてのフィブリンシーラント
US7304208B2 (en) * 2000-05-02 2007-12-04 Ventria Bioscience Expression of human serum albumin (HSA) in monocot seeds
NL1020426C2 (nl) 2002-04-18 2003-10-21 Tno Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen.
CA2525493C (en) * 2003-04-11 2018-10-30 Ventria Bioscience Human blood proteins expressed in oryza seeds
WO2005010178A1 (ja) * 2003-07-29 2005-02-03 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 組換えフィブリノゲン高産生細胞の作製方法及び高産生細胞
KR20070013323A (ko) * 2004-05-07 2007-01-30 더 리전츠 오브 더 유니버시티 오브 캘리포니아 피브리노겐 감마쇄 ｃ-말단 단편에 의해 유도된 내피 세포아폽토시스
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers
ES2864039T3 (es) * 2005-05-20 2021-10-13 Lonza Biologics Plc Expresión de alto nivel de un anticuerpo recombinante en una célula huésped de mamífero
EP1996186A4 (en) 2006-03-06 2009-07-22 Humagene Inc PROCESS FOR THE PREPARATION OF RECOMBINANT HUMAN THROMBIN AND FIBRINOGEN

Also Published As

Publication number Publication date
EP3078673A2 (en) 2016-10-12
NZ590871A (en) 2012-07-27
PL2310411T3 (pl) 2017-02-28
EP3078673A3 (en) 2017-02-22
CN102089322A (zh) 2011-06-08
JP2011527190A (ja) 2011-10-27
WO2010004004A1 (en) 2010-01-14
HK1151184A1 (zh) 2012-01-13
KR20110040895A (ko) 2011-04-20
JP5819725B2 (ja) 2015-11-24
US10562956B2 (en) 2020-02-18
EP2310411B2 (en) 2019-03-20
IL210495A (en) 2016-02-29
AU2009268052B2 (en) 2015-05-28
CA2730030C (en) 2019-09-03
EP2310411B1 (en) 2016-05-11
BRPI0915574A2 (pt) 2016-07-26
CN102089322B (zh) 2015-09-23
US20110177524A1 (en) 2011-07-21
EP2310411A1 (en) 2011-04-20
IL210495A0 (en) 2011-03-31
ES2585246T3 (es) 2016-10-04
US20170037108A1 (en) 2017-02-09
AU2009268052A1 (en) 2010-01-14
CA2730030A1 (en) 2010-01-14

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