ME02951B - Amino-supstituisani imidazopiridazini - Google Patents

Amino-supstituisani imidazopiridazini

Info

Publication number: ME02951B
Authority: ME; Montenegro
Prior art keywords: amino; substituted imidazopyridazines; imidazopyridazines; substituted
Prior art date: 2011-09-06

Application number

MEP-2017-191A

Other languages

German (de)

English (en)

French (fr)

Inventor

Knut Eis

Florian Pühler

Ludwig Zorn

Arne Scholz

Philip Lienau

Mark Jean Gnoth

Ulf Bömer

Judith Günther

Marion Hitchcock

Original Assignee

Bayer Ip Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-09-06

Filing date

2012-09-05

Publication date

2018-07-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47831558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME02951(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-09-05 Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh

2018-07-20 Publication of ME02951B publication Critical patent/ME02951B/me

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Rheumatology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cosmetics (AREA)
Fats And Perfumes (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MEP-2017-191A 2011-09-06 2012-09-05 Amino-supstituisani imidazopiridazini ME02951B (me)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
EP11180129		2011-09-06
EP11182440		2011-09-23
EP12179902		2012-08-09
EP12761564.9A EP2758401B1 (en)	2011-09-06	2012-09-05	Amino-substituted imidazopyridazines
PCT/EP2012/067264 WO2013034570A1 (en)	2011-09-06	2012-09-05	Amino-substituted imidazopyridazines

Publications (1)

Publication Number	Publication Date
ME02951B true ME02951B (me)	2018-07-20

Family

ID=47831558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MEP-2017-191A ME02951B (me)	2011-09-06	2012-09-05	Amino-supstituisani imidazopiridazini

Country Status (36)

Country	Link
US (1)	US9499547B2 (me)
EP (1)	EP2758401B1 (me)
JP (1)	JP6174583B2 (me)
KR (1)	KR20140059268A (me)
CN (1)	CN103958515B (me)
AP (1)	AP2014007496A0 (me)
AU (1)	AU2012306422B2 (me)
BR (1)	BR112014004687A2 (me)
CA (1)	CA2847514A1 (me)
CL (1)	CL2014000543A1 (me)
CO (1)	CO6900146A2 (me)
CR (1)	CR20140113A (me)
CY (1)	CY1119433T1 (me)
DK (1)	DK2758401T3 (me)
DO (1)	DOP2014000051A (me)
EA (1)	EA025688B1 (me)
EC (1)	ECSP14013231A (me)
ES (1)	ES2638319T3 (me)
GT (1)	GT201400043A (me)
HK (1)	HK1199732A1 (me)
HR (1)	HRP20171248T1 (me)
IL (1)	IL231351A (me)
LT (1)	LT2758401T (me)
MA (1)	MA35422B1 (me)
ME (1)	ME02951B (me)
MX (1)	MX348064B (me)
MY (1)	MY168413A (me)
PE (1)	PE20141593A1 (me)
PL (1)	PL2758401T3 (me)
PT (1)	PT2758401T (me)
RS (1)	RS56179B1 (me)
SG (1)	SG11201400219PA (me)
SI (1)	SI2758401T1 (me)
UA (1)	UA117092C2 (me)
WO (1)	WO2013034570A1 (me)
ZA (1)	ZA201402498B (me)

Families Citing this family (23)

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CN103717604B (zh)	2011-06-01	2016-06-01	拜耳知识产权有限责任公司	取代的氨基咪唑并哒嗪
UA117092C2 (uk)	2011-09-06	2018-06-25	Байєр Інтеллектуал Проперті Гмбх	Амінозаміщені імідазопіридазини
US9320737B2 (en) *	2011-09-23	2016-04-26	Bayer Intellectual Property Gmbh	Substituted imidazopyridazines
JP6147761B2 (ja)	2011-12-12	2017-06-14	バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＧｍｂＨ	アミノ置換イミダゾピリダジン
JP6173426B2 (ja) *	2012-03-29	2017-08-02	バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＧｍｂＨ	アミノ置換イミダゾピリダジン
US9409889B2 (en)	2012-04-04	2016-08-09	Bayer Pharma Aktiengesellschaft	Amino-substituted imidazopyridazines
ES2646916T3 (es)	2012-11-19	2017-12-18	Bayer Pharma Aktiengesellschaft	Aminoimidazopiridazinas como inhibidores de MKNK1 cinasa
ES2649156T3 (es)	2013-01-14	2018-01-10	Incyte Holdings Corporation	Compuestos bicíclicos de carboxamida aromática útiles como inhibidores de quinasas Pim
CN105051029B (zh)	2013-01-15	2018-07-31	因赛特公司	可用作pim激酶抑制剂的噻唑甲酰胺和吡啶甲酰胺化合物
WO2014118135A1 (en) *	2013-01-30	2014-08-07	Bayer Pharma Aktiengesellschaft	Amidoimidazopyridazines as mknk-1 kinase inhibitors
US20160287589A1 (en) *	2013-02-20	2016-10-06	Bayer Pharma Aktiengesellschaft	Substituted-imidazopyridazines
WO2015027124A1 (en)	2013-08-23	2015-02-26	Incyte Corporation	Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
CN105899512A (zh)	2014-01-09	2016-08-24	拜耳医药股份公司	可用于治疗过度增殖性和/或血管生成疾病的酰胺基团取代的咪唑并哒嗪
WO2016010897A1 (en)	2014-07-14	2016-01-21	Incyte Corporation	Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
US9580418B2 (en)	2014-07-14	2017-02-28	Incyte Corporation	Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
US20180022750A1 (en) *	2014-12-23	2018-01-25	Bayer Pharma Aktiengesellschaft	6-hydroxybenzofuranyl- and 6-alkoxybenzofuranyl-substituted imidazopyridazines
DK3285809T3 (da)	2015-04-20	2019-11-18	Effector Therapeutics Inc	Inhibitorer af immunkontrolpunktsmodulatorer til anvendelse i behandling af kræft og infektioner.
US9540347B2 (en)	2015-05-29	2017-01-10	Incyte Corporation	Pyridineamine compounds useful as Pim kinase inhibitors
AR105967A1 (es)	2015-09-09	2017-11-29	Incyte Corp	Sales de un inhibidor de pim quinasa
TW201718546A (zh)	2015-10-02	2017-06-01	英塞特公司	適用作pim激酶抑制劑之雜環化合物
EP3397774A1 (en) *	2015-12-31	2018-11-07	Effector Therapeutics Inc.	Mnk biomarkers and uses thereof
WO2017157418A1 (en)	2016-03-15	2017-09-21	Bayer Pharma Aktiengesellschaft	Combination of mknk1-inhibitors
AR113922A1 (es)	2017-12-08	2020-07-01	Incyte Corp	Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas

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US20140288069A1 (en)	2011-05-17	2014-09-25	Bayer Intellectual Property Gmbh	Amino-substituted imidazopyridazines as mknk1 kinase inhibitors
CN103717604B (zh)	2011-06-01	2016-06-01	拜耳知识产权有限责任公司	取代的氨基咪唑并哒嗪
ES2610366T3 (es)	2011-06-22	2017-04-27	Bayer Intellectual Property Gmbh	Heterociclil-aminoimidazopiridazinas
AR087701A1 (es)	2011-08-31	2014-04-09	Japan Tobacco Inc	Derivados de pirazol con actividad inhibidora de sglt1
JO3192B1 (ar)	2011-09-06	2018-03-08	Novartis Ag	مركب بنزوثيازولون
UA117092C2 (uk)	2011-09-06	2018-06-25	Байєр Інтеллектуал Проперті Гмбх	Амінозаміщені імідазопіридазини
US9353081B2 (en)	2011-09-23	2016-05-31	Hoffmann-La Roche Inc.	Bicyclic dihydroquinoline-2-one derivatives
US9320737B2 (en)	2011-09-23	2016-04-26	Bayer Intellectual Property Gmbh	Substituted imidazopyridazines
JP6147761B2 (ja)	2011-12-12	2017-06-14	バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＧｍｂＨ	アミノ置換イミダゾピリダジン
JP6173426B2 (ja)	2012-03-29	2017-08-02	バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＧｍｂＨ	アミノ置換イミダゾピリダジン
US9409889B2 (en)	2012-04-04	2016-08-09	Bayer Pharma Aktiengesellschaft	Amino-substituted imidazopyridazines
ES2646916T3 (es)	2012-11-19	2017-12-18	Bayer Pharma Aktiengesellschaft	Aminoimidazopiridazinas como inhibidores de MKNK1 cinasa
WO2014118135A1 (en)	2013-01-30	2014-08-07	Bayer Pharma Aktiengesellschaft	Amidoimidazopyridazines as mknk-1 kinase inhibitors
US20160287589A1 (en)	2013-02-20	2016-10-06	Bayer Pharma Aktiengesellschaft	Substituted-imidazopyridazines
CN105899512A (zh)	2014-01-09	2016-08-24	拜耳医药股份公司	可用于治疗过度增殖性和/或血管生成疾病的酰胺基团取代的咪唑并哒嗪

2012
- 2012-05-09 UA UAA201403426A patent/UA117092C2/uk unknown
- 2012-09-05 CN CN201280047525.XA patent/CN103958515B/zh not_active Expired - Fee Related
- 2012-09-05 PT PT127615649T patent/PT2758401T/pt unknown
- 2012-09-05 AP AP2014007496A patent/AP2014007496A0/xx unknown
- 2012-09-05 ES ES12761564.9T patent/ES2638319T3/es active Active
- 2012-09-05 SG SG11201400219PA patent/SG11201400219PA/en unknown
- 2012-09-05 LT LTEP12761564.9T patent/LT2758401T/lt unknown
- 2012-09-05 MY MYPI2014700492A patent/MY168413A/en unknown
- 2012-09-05 DK DK12761564.9T patent/DK2758401T3/en active
- 2012-09-05 US US14/342,977 patent/US9499547B2/en not_active Expired - Fee Related
- 2012-09-05 RS RS20170812A patent/RS56179B1/sr unknown
- 2012-09-05 BR BR112014004687A patent/BR112014004687A2/pt not_active IP Right Cessation
- 2012-09-05 JP JP2014528955A patent/JP6174583B2/ja not_active Expired - Fee Related
- 2012-09-05 MX MX2014002697A patent/MX348064B/es active IP Right Grant
- 2012-09-05 AU AU2012306422A patent/AU2012306422B2/en not_active Ceased
- 2012-09-05 EP EP12761564.9A patent/EP2758401B1/en active Active
- 2012-09-05 SI SI201231035T patent/SI2758401T1/sl unknown
- 2012-09-05 CA CA2847514A patent/CA2847514A1/en not_active Abandoned
- 2012-09-05 ME MEP-2017-191A patent/ME02951B/me unknown
- 2012-09-05 PL PL12761564T patent/PL2758401T3/pl unknown
- 2012-09-05 WO PCT/EP2012/067264 patent/WO2013034570A1/en active Application Filing
- 2012-09-05 EA EA201400311A patent/EA025688B1/ru not_active IP Right Cessation
- 2012-09-05 KR KR1020147008395A patent/KR20140059268A/ko not_active Application Discontinuation
- 2012-09-05 PE PE2014000307A patent/PE20141593A1/es not_active Application Discontinuation
2014
- 2014-03-05 MA MA36793A patent/MA35422B1/fr unknown
- 2014-03-06 DO DO2014000051A patent/DOP2014000051A/es unknown
- 2014-03-06 IL IL231351A patent/IL231351A/en not_active IP Right Cessation
- 2014-03-06 GT GT201400043A patent/GT201400043A/es unknown
- 2014-03-06 CR CR20140113A patent/CR20140113A/es unknown
- 2014-03-06 EC ECSP14013231 patent/ECSP14013231A/es unknown
- 2014-03-06 CL CL2014000543A patent/CL2014000543A1/es unknown
- 2014-03-06 CO CO14048372A patent/CO6900146A2/es unknown
- 2014-04-04 ZA ZA2014/02498A patent/ZA201402498B/en unknown
2015
- 2015-01-08 HK HK15100198.3A patent/HK1199732A1/xx not_active IP Right Cessation
2017
- 2017-08-16 HR HRP20171248TT patent/HRP20171248T1/hr unknown
- 2017-08-23 CY CY20171100892T patent/CY1119433T1/el unknown

Also Published As

Publication number	Publication date
ES2638319T3 (es)	2017-10-19
EA025688B1 (ru)	2017-01-30
RS56179B1 (sr)	2017-11-30
MY168413A (en)	2018-11-09
CL2014000543A1 (es)	2014-09-26
LT2758401T (lt)	2017-08-25
MX348064B (es)	2017-05-26
SG11201400219PA (en)	2014-03-28
AU2012306422B2 (en)	2017-10-26
EP2758401B1 (en)	2017-05-31
GT201400043A (es)	2015-04-06
PE20141593A1 (es)	2014-11-12
EP2758401A1 (en)	2014-07-30
NZ622129A (en)	2016-06-24
ZA201402498B (en)	2017-09-27
CN103958515B (zh)	2016-11-09
CR20140113A (es)	2014-05-02
HK1199732A1 (en)	2015-07-17
DK2758401T3 (en)	2017-09-11
AP2014007496A0 (en)	2014-03-31
CY1119433T1 (el)	2018-03-07
UA117092C2 (uk)	2018-06-25
MA35422B1 (fr)	2014-09-01
KR20140059268A (ko)	2014-05-15
AU2012306422A1 (en)	2014-03-27
DOP2014000051A (es)	2014-06-01
IL231351A (en)	2017-01-31
CA2847514A1 (en)	2013-03-14
PL2758401T3 (pl)	2017-11-30
ECSP14013231A (es)	2014-04-30
US20140296231A1 (en)	2014-10-02
HRP20171248T1 (hr)	2017-10-20
PT2758401T (pt)	2017-08-30
IL231351A0 (en)	2014-04-30
MX2014002697A (es)	2014-04-25
JP6174583B2 (ja)	2017-08-02
BR112014004687A2 (pt)	2017-03-28
SI2758401T1 (sl)	2017-10-30
CN103958515A (zh)	2014-07-30
CO6900146A2 (es)	2014-03-20
US9499547B2 (en)	2016-11-22
AP3853A (me)	2016-09-30
WO2013034570A1 (en)	2013-03-14
EA201400311A1 (ru)	2014-09-30
JP2014525469A (ja)	2014-09-29

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