LU77530A1 - Procede et composes intermediaires pour la preparation de certaines 2-(piperazin-1-yle 4-substitue)-4-amino-quinazolines - Google Patents

Procede et composes intermediaires pour la preparation de certaines 2-(piperazin-1-yle 4-substitue)-4-amino-quinazolines

Info

Publication number: LU77530A1
Authority: LU; Luxembourg
Prior art keywords: substitue; yle; quinazolines; piperazin; amino
Prior art date: 1976-06-15

Application number

LU77530A

Other languages

English (en)

French (fr)

Inventor

P Hammen

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-15

Filing date

1977-06-13

Publication date

1979-03-26

1977-06-13 Application filed by Pfizer filed Critical Pfizer

1979-03-26 Publication of LU77530A1 publication Critical patent/LU77530A1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

LU77530A 1976-06-15 1977-06-13 Procede et composes intermediaires pour la preparation de certaines 2-(piperazin-1-yle 4-substitue)-4-amino-quinazolines LU77530A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US69620176A	1976-06-15	1976-06-15

Publications (1)

Publication Number	Publication Date
LU77530A1 true LU77530A1 (fr)	1979-03-26

Family

ID=24796111

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU77530A LU77530A1 (fr)	1976-06-15	1977-06-13	Procede et composes intermediaires pour la preparation de certaines 2-(piperazin-1-yle 4-substitue)-4-amino-quinazolines

Country Status (34)

Country	Link
JP (1)	JPS52153985A (sv)
AR (1)	AR218251A1 (sv)
AT (1)	AT356115B (sv)
BE (1)	BE855656A (sv)
BG (3)	BG35594A3 (sv)
CA (1)	CA1068698A (sv)
CH (3)	CH638203A5 (sv)
CS (1)	CS202069B2 (sv)
DD (1)	DD131021A5 (sv)
DE (1)	DE2725019A1 (sv)
DK (1)	DK146625C (sv)
EG (1)	EG12922A (sv)
ES (1)	ES459364A1 (sv)
FI (1)	FI66853C (sv)
FR (1)	FR2355015A1 (sv)
GB (1)	GB1548856A (sv)
GR (1)	GR72288B (sv)
HK (1)	HK31481A (sv)
HU (1)	HU177883B (sv)
IE (1)	IE45423B1 (sv)
IL (1)	IL52167A (sv)
LU (1)	LU77530A1 (sv)
MY (1)	MY8100270A (sv)
NL (1)	NL172543C (sv)
NO (1)	NO147838C (sv)
NZ (1)	NZ184168A (sv)
PH (1)	PH22196A (sv)
PL (3)	PL111221B1 (sv)
PT (1)	PT66617B (sv)
RO (3)	RO77330A (sv)
SE (2)	SE435380B (sv)
SU (2)	SU1033002A3 (sv)
YU (1)	YU40164B (sv)
ZA (1)	ZA773014B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3346675A1 (de) *	1983-12-23	1985-07-04	Beiersdorf Ag, 2000 Hamburg	Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) *	1985-12-04	1987-10-12	Gerot Pharmazeutika	Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) *	1992-08-31	2001-04-10	Khashayar Karimian	Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) *	1994-01-25	1997-10-21	Warner-Lambert Company	Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) *	1994-01-25	2001-11-25	Warner Lambert Co	Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en)	1994-01-25	1995-03-30	Warner Lambert Co	Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) *	1996-02-02	1999-08-03	Nitromed, Inc.	Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3511836A (en)	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3669968A (en)	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines
JPS4966691A (sv) *	1972-10-30	1974-06-27
US3935213A (en)	1973-12-05	1976-01-27	Pfizer Inc.	Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (sv) *	1974-03-25	1975-10-04

1977
- 1977-05-16 SE SE7705745A patent/SE435380B/sv not_active IP Right Cessation
- 1977-05-18 CA CA278,728A patent/CA1068698A/en not_active Expired
- 1977-05-20 GR GR53521A patent/GR72288B/el unknown
- 1977-05-20 NZ NZ184168A patent/NZ184168A/xx unknown
- 1977-05-20 ZA ZA00773014A patent/ZA773014B/xx unknown
- 1977-05-25 IL IL52167A patent/IL52167A/xx unknown
- 1977-05-27 YU YU1326/77A patent/YU40164B/xx unknown
- 1977-05-31 JP JP6391877A patent/JPS52153985A/ja active Granted
- 1977-05-31 DE DE19772725019 patent/DE2725019A1/de active Pending
- 1977-05-31 PT PT66617A patent/PT66617B/pt unknown
- 1977-05-31 NL NLAANVRAGE7705939,A patent/NL172543C/xx not_active IP Right Cessation
- 1977-06-01 ES ES459364A patent/ES459364A1/es not_active Expired
- 1977-06-01 AT AT386977A patent/AT356115B/de not_active IP Right Cessation
- 1977-06-01 NO NO771919A patent/NO147838C/no unknown
- 1977-06-01 EG EG338/77A patent/EG12922A/xx active
- 1977-06-01 DK DK240877A patent/DK146625C/da not_active IP Right Cessation
- 1977-06-01 FI FI771741A patent/FI66853C/fi not_active IP Right Cessation
- 1977-06-01 CH CH673777A patent/CH638203A5/de not_active IP Right Cessation
- 1977-06-02 AR AR267927A patent/AR218251A1/es active
- 1977-06-03 BG BG036493A patent/BG35594A3/xx unknown
- 1977-06-03 BG BG057396A patent/BG35748A3/xx unknown
- 1977-06-03 BG BG057395A patent/BG35747A3/xx unknown
- 1977-06-13 LU LU77530A patent/LU77530A1/xx unknown
- 1977-06-14 RO RO7798088A patent/RO77330A/ro unknown
- 1977-06-14 SU SU772497901A patent/SU1033002A3/ru active
- 1977-06-14 IE IE1212/77A patent/IE45423B1/en not_active IP Right Cessation
- 1977-06-14 FR FR7718206A patent/FR2355015A1/fr active Granted
- 1977-06-14 RO RO7798087A patent/RO77308A/ro unknown
- 1977-06-14 RO RO7790683A patent/RO73050A/ro unknown
- 1977-06-14 GB GB24841/77A patent/GB1548856A/en not_active Expired
- 1977-06-14 BE BE178416A patent/BE855656A/xx not_active IP Right Cessation
- 1977-06-14 HU HU77PI578A patent/HU177883B/hu not_active IP Right Cessation
- 1977-06-15 PL PL1977211798A patent/PL111221B1/pl unknown
- 1977-06-15 CS CS773960A patent/CS202069B2/cs unknown
- 1977-06-15 PL PL1977198874A patent/PL105558B1/pl unknown
- 1977-06-15 PL PL1977211797A patent/PL113012B1/pl unknown
- 1977-06-15 DD DD7700199502A patent/DD131021A5/xx unknown
1978
- 1978-01-03 PH PH20606A patent/PH22196A/en unknown
- 1978-06-28 SU SU782630798A patent/SU946402A3/ru active
1981
- 1981-07-02 HK HK314/81A patent/HK31481A/xx unknown
- 1981-12-16 SE SE8107554A patent/SE450120B/sv not_active IP Right Cessation
- 1981-12-30 MY MY270/81A patent/MY8100270A/xx unknown
1982
- 1982-04-22 CH CH245782A patent/CH638517A5/de not_active IP Right Cessation
- 1982-04-22 CH CH245682A patent/CH638516A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL52167A (en)	1981-01-30
BG35748A3 (en)	1984-06-15
CH638203A5 (en)	1983-09-15
CH638517A5 (en)	1983-09-30
NZ184168A (en)	1979-08-31
FI66853B (fi)	1984-08-31
AR218251A1 (es)	1980-05-30
AU2558377A (en)	1978-09-07
PH22196A (en)	1988-06-28
MY8100270A (en)	1981-12-31
DD131021A5 (de)	1978-05-24
FI771741A (sv)	1977-12-16
DK146625C (da)	1984-06-04
GB1548856A (en)	1979-07-18
NO147838C (no)	1983-06-22
AT356115B (de)	1980-04-10
IE45423L (en)	1977-12-15
SE7705745L (sv)	1977-12-16
PL113012B1 (en)	1980-11-29
BG35747A3 (en)	1984-06-15
IE45423B1 (en)	1982-08-25
CA1068698A (en)	1979-12-25
ZA773014B (en)	1978-04-26
SE435380B (sv)	1984-09-24
ATA386977A (de)	1979-09-15
SU946402A3 (ru)	1982-07-23
DK240877A (da)	1977-12-16
NL172543C (nl)	1983-09-16
YU132677A (en)	1982-08-31
RO73050A (ro)	1981-08-30
YU40164B (en)	1985-08-31
BG35594A3 (en)	1984-05-15
PT66617A (en)	1977-06-01
DK146625B (da)	1983-11-21
NO147838B (no)	1983-03-14
IL52167A0 (en)	1977-07-31
NL7705939A (nl)	1977-12-19
DE2725019A1 (de)	1977-12-22
SE8107554L (sv)	1981-12-16
FR2355015B1 (sv)	1981-07-24
CS202069B2 (en)	1980-12-31
CH638516A5 (en)	1983-09-30
PL105558B1 (pl)	1979-10-31
RO77308A (ro)	1981-08-17
HK31481A (en)	1981-07-10
HU177883B (en)	1982-01-28
PT66617B (en)	1978-10-27
PL198874A1 (pl)	1978-04-10
BE855656A (fr)	1977-12-14
EG12922A (en)	1980-03-31
SE450120B (sv)	1987-06-09
RO77330A (ro)	1981-06-22
GR72288B (sv)	1983-10-17
NO771919L (no)	1977-12-16
JPS52153985A (en)	1977-12-21
NL172543B (nl)	1983-04-18
FR2355015A1 (fr)	1978-01-13
ES459364A1 (es)	1978-03-16
FI66853C (fi)	1984-12-10
JPS5543465B2 (sv)	1980-11-06
PL111221B1 (en)	1980-08-30
SU1033002A3 (ru)	1983-07-30

Publication	Publication Date	Title
PT71864A (fr)	1980-11-01	Procede pour la preparation de composes hetherocicliques
BE861172A (fr)	1978-05-24	Procede de preparation d'alpha-amino-amides
BE884650A (fr)	1981-02-06	Procede pour la preparation de diesterdiamides
RO70854A (ro)	1981-06-26	Procedeu de preparare a meta-ariloxibenzaldehidelor
BE885977A (fr)	1981-04-30	Procede pour la preparation de dithiazolyldisulfures
RO70462A (ro)	1981-01-30	Procedeu pentru prepararea unor 3-halometilcefemi
LU77530A1 (fr)	1979-03-26	Procede et composes intermediaires pour la preparation de certaines 2-(piperazin-1-yle 4-substitue)-4-amino-quinazolines
RO71572A (ro)	1982-07-06	Procedeu pentru prepararea unor o0imcarbamati n-sulfenilati
RO71066A (ro)	1982-10-26	Procedeu pentru prepararea unor 2-clorsulfinilazetidin-4-one
MC1345A1 (fr)	1981-06-22	Procede pour la preparation de composes heterocycliques
PT66882A (fr)	1977-09-01	Procede pour la preparation de composes anti-bacteriques
RO77935A (ro)	1981-12-25	Procedeu pentru prepararea unor cis-4a-ariloctahidro-1h-2-pirinidine
BE857650A (fr)	1977-12-01	Procede de preparation de composes d'alcoxymethylene
RO72831A (ro)	1983-08-03	Procedeu pentru prepararea unor fenilpiperazine
BE867086A (fr)	1978-11-16	Composes d'azacyclyle et procede pour leur preparation
BE867414A (fr)	1978-09-18	Procede pour la preparation d'hydroxy-alpha-aminobenzylpenicillines
BE867228A (fr)	1978-11-20	Procede pour la preparation d'hydroxyphenylglycocolles
BE881425A (fr)	1980-07-30	Procede de preparation de composes beta-lactame
RO83713A (ro)	1984-05-23	Procedeu pentru prepararea unor haloacilamide
RO70052A (ro)	1980-07-15	Procedeu pentru prepararea unor 7-alcoxi-3-clormetilcefemi
RO78325A (ro)	1982-04-12	Procedeu pentru prepararea unor compusi heterociclici
FR2444037B1 (fr)	1985-09-20	Procede de preparation de 10-bromovincamines et composes obtenus
RO71742A (ro)	1982-02-26	Procedeu pentru prepararea unor 1-oxadetiacefalosporine
BE857738A (fr)	1978-02-13	Procede de preparation d'alkylphosphines
PT66065B (fr)	1978-06-23	Procede pour la preparation de hydrocarbonetes