LT2963043T - Tetrahidroimidazo[1,5-d][1,4]oksazepino darinys - Google Patents
Tetrahidroimidazo[1,5-d][1,4]oksazepino darinysInfo
- Publication number
- LT2963043T LT2963043T LTEP14756740.8T LT14756740T LT2963043T LT 2963043 T LT2963043 T LT 2963043T LT 14756740 T LT14756740 T LT 14756740T LT 2963043 T LT2963043 T LT 2963043T
- Authority
- LT
- Lithuania
- Prior art keywords
- tetrahydroimidazo
- oxazepine derivative
- oxazepine
- derivative
- Prior art date
Links
- FBTZTHLFUZVXGB-UHFFFAOYSA-N 1,2,3,5,6,8-hexahydroimidazo[1,5-d][1,4]oxazepine Chemical class C1OCCN2CNCC2=C1 FBTZTHLFUZVXGB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361770469P | 2013-02-28 | 2013-02-28 | |
| PCT/JP2014/054724 WO2014133022A1 (ja) | 2013-02-28 | 2014-02-26 | テトラヒドロイミダゾ［１，５－ｄ］［１，４］オキサゼピン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2963043T true LT2963043T (lt) | 2018-10-10 |
Family
ID=51388759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP14756740.8T LT2963043T (lt) | 2013-02-28 | 2014-02-26 | Tetrahidroimidazo[1,5-d][1,4]oksazepino darinys |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US9458176B2 (lt) |
| EP (1) | EP2963043B1 (lt) |
| JP (1) | JP5654715B1 (lt) |
| KR (1) | KR102190597B1 (lt) |
| CN (1) | CN105008375B (lt) |
| AR (1) | AR094887A1 (lt) |
| AU (1) | AU2014221775B2 (lt) |
| BR (1) | BR112015020545A2 (lt) |
| CA (1) | CA2901168C (lt) |
| CL (1) | CL2015002391A1 (lt) |
| CY (1) | CY1121231T1 (lt) |
| DK (1) | DK2963043T3 (lt) |
| ES (1) | ES2685025T3 (lt) |
| HK (1) | HK1217697A1 (lt) |
| HR (1) | HRP20181349T1 (lt) |
| HU (1) | HUE040219T2 (lt) |
| IL (1) | IL240402A (lt) |
| LT (1) | LT2963043T (lt) |
| MX (1) | MX362920B (lt) |
| PE (1) | PE20151651A1 (lt) |
| PH (1) | PH12015501878A1 (lt) |
| PL (1) | PL2963043T3 (lt) |
| PT (1) | PT2963043T (lt) |
| RS (1) | RS57602B1 (lt) |
| RU (1) | RU2659219C2 (lt) |
| SG (1) | SG11201505252VA (lt) |
| SI (1) | SI2963043T1 (lt) |
| TW (1) | TWI622592B (lt) |
| UA (1) | UA114950C2 (lt) |
| WO (1) | WO2014133022A1 (lt) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2705950T3 (es) | 2011-06-03 | 2019-03-27 | Eisai R&D Man Co Ltd | Biomarcadores para predecir y valorar la capacidad de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib |
| SG11201402660YA (en) | 2011-12-21 | 2014-10-30 | Novira Therapeutics Inc | Hepatitis b antiviral agents |
| KR102122244B1 (ko) | 2012-08-28 | 2020-06-15 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 설파모일-아릴아미드 및 b형 간염 치료제로서의 그 용도 |
| BR112015020242A2 (pt) | 2013-02-28 | 2017-07-18 | Janssen Sciences Ireland Uc | sulfamoil-arilamidas e seu uso como medicamentos para o tratamento da hepatite b |
| EP2981536B1 (en) | 2013-04-03 | 2017-06-14 | Janssen Sciences Ireland UC | N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| KR102204279B1 (ko) | 2013-05-14 | 2021-01-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 자궁내막암 대상의 렌바티닙 화합물에 대한 반응성을 예측 및 평가하기 위한 생체표지 |
| JO3603B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
| CN105960400B (zh) | 2013-05-17 | 2019-05-31 | 爱尔兰詹森科学公司 | 氨磺酰基噻吩酰胺衍生物及其作为药物用于治疗乙型肝炎的用途 |
| SG10201805033XA (en) | 2013-07-25 | 2018-07-30 | Janssen Sciences Ireland Uc | Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| WO2015059212A1 (en) | 2013-10-23 | 2015-04-30 | Janssen R&D Ireland | Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| US9169212B2 (en) | 2014-01-16 | 2015-10-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| RU2702109C1 (ru) | 2014-02-05 | 2019-10-04 | Новира Терапьютикс, Инк. | Комбинированная терапия для лечения инфекций вгв |
| AP2016009257A0 (en) | 2014-02-06 | 2016-06-30 | Janssen Sciences Ireland Uc | Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| JP2017206438A (ja) * | 2014-08-22 | 2017-11-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | テトラヒドロイミダゾ［１，５−ｄ］［１，４］オキサゼピン化合物（ＴＥＴＲＡＨＹＤＲＯＩＭＩＤＡＺＯ［１，５−ｄ］［１，４］ＯＸＡＺＥＰＩＮＥＣＯＭＰＯＵＮＤ） |
| WO2016033190A1 (en) * | 2014-08-27 | 2016-03-03 | Eisai, Inc. | Radiotracer compounds |
| EP4089076A1 (en) | 2014-08-28 | 2022-11-16 | Eisai R&D Management Co., Ltd. | High-purity quinoline derivative and method for manufacturing same |
| ES2967362T3 (es) | 2015-02-25 | 2024-04-29 | Eisai R&D Man Co Ltd | Método para suprimir el amargor de un derivado de quinolina |
| CA2978226A1 (en) | 2015-03-04 | 2016-09-09 | Merck Sharpe & Dohme Corp. | Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer |
| CN107847762A (zh) | 2015-03-19 | 2018-03-27 | 诺维拉治疗公司 | 氮杂环辛烷和氮杂环壬烷衍生物以及治疗乙型肝炎感染的方法 |
| US11369623B2 (en) | 2015-06-16 | 2022-06-28 | Prism Pharma Co., Ltd. | Anticancer combination of a CBP/catenin inhibitor and an immune checkpoint inhibitor |
| US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| EP3356328A1 (en) | 2015-09-29 | 2018-08-08 | Novira Therapeutics, Inc. | Crystalline forms of a hepatitis b antiviral agent |
| BR112018071048A2 (pt) | 2016-04-15 | 2019-05-07 | Janssen Sciences Ireland Uc | combinações e métodos que compreendem um inibidor da montagem de capsídeos |
| MX2019008230A (es) | 2017-01-10 | 2019-10-24 | Bayer Ag | Derivados heterociclicos como agentes de control de plagas. |
| WO2018130437A1 (de) | 2017-01-10 | 2018-07-19 | Bayer Aktiengesellschaft | Heterocyclen-derivate als schädlingsbekämpfungsmittel |
| JP2021035911A (ja) * | 2017-11-15 | 2021-03-04 | 大日本住友製薬株式会社 | 縮環ピラゾール誘導体及びその医薬用途 |
| US11633395B2 (en) | 2017-11-24 | 2023-04-25 | Sumitomo Pharma Co., Ltd. | Substituted pyrazolo[1,5-a]pyrazines as negative allosteric modulators of group II metabotropic glutamate receptor |
| SG11202007097QA (en) | 2018-03-14 | 2020-08-28 | Janssen Sciences Ireland Unlimited Co | Capsid assembly modulator dosing regimen |
| TWI820231B (zh) | 2018-10-11 | 2023-11-01 | 德商拜耳廠股份有限公司 | 用於製備經取代咪唑衍生物之方法 |
| TW202045499A (zh) | 2019-02-22 | 2020-12-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 用於治療ｈｂｖ感染或ｈｂｖ誘發疾病之醯胺衍生物 |
| MA55879A (fr) | 2019-05-06 | 2022-03-16 | Janssen Sciences Ireland Unlimited Co | Dérivés d'amide utiles dans le traitement d'une infection par le virus de l'hépatite b ou de maladies induites par le virus de l'hépatite b |
| US11155547B1 (en) * | 2020-06-18 | 2021-10-26 | Alterity Therapeutics Limited | Compounds for and methods of treating diseases |
| WO2022002818A1 (de) | 2020-07-02 | 2022-01-06 | Bayer Aktiengesellschaft | Heterocyclen-derivate als schädlingsbekämpfungsmittel |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL367086A1 (en) * | 2001-04-12 | 2005-02-21 | F.Hoffmann-La Roche Ag | Dihydro-benzo[b][1,4]diazepin-2-one derivatives as mglur2 antagonists i |
| MX2007011483A (es) * | 2005-03-23 | 2007-10-12 | Hoffmann La Roche | Derivados de acetilenil-pirazolo-pirimidina como antagonistas de glutamato metabotropico 2. |
| CN101273040B (zh) | 2005-09-27 | 2011-11-09 | 弗·哈夫曼-拉罗切有限公司 | 作为mglur2拮抗剂的*二唑基吡唑并嘧啶类化合物 |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
| US8739050B2 (en) | 2008-03-07 | 2014-05-27 | 9224-5489 Quebec Inc. | Documents discrimination system and method thereof |
| MX2011005242A (es) * | 2008-11-28 | 2011-09-06 | Ortho Mcneil Janssen Pharm | Derivados de indol y benzoxazina como moduladores de los receptores de glutamato metabotropicos. |
| US8835422B2 (en) | 2008-12-11 | 2014-09-16 | Cara Therapeutics, Inc. | Substituted imidazoheterocycle derivatives |
| WO2010075203A1 (en) | 2008-12-22 | 2010-07-01 | Schering Corporation | Gamma secretase modulators |
-
2014
- 2014-02-26 RS RS20180992A patent/RS57602B1/sr unknown
- 2014-02-26 PE PE2015001791A patent/PE20151651A1/es unknown
- 2014-02-26 DK DK14756740.8T patent/DK2963043T3/en active
- 2014-02-26 CN CN201480009750.3A patent/CN105008375B/zh not_active Expired - Fee Related
- 2014-02-26 SG SG11201505252VA patent/SG11201505252VA/en unknown
- 2014-02-26 JP JP2014541469A patent/JP5654715B1/ja active Active
- 2014-02-26 CA CA2901168A patent/CA2901168C/en active Active
- 2014-02-26 TW TW103106584A patent/TWI622592B/zh not_active IP Right Cessation
- 2014-02-26 SI SI201430830T patent/SI2963043T1/sl unknown
- 2014-02-26 PL PL14756740T patent/PL2963043T3/pl unknown
- 2014-02-26 KR KR1020157022943A patent/KR102190597B1/ko active IP Right Grant
- 2014-02-26 AR ARP140100595A patent/AR094887A1/es unknown
- 2014-02-26 PT PT14756740T patent/PT2963043T/pt unknown
- 2014-02-26 WO PCT/JP2014/054724 patent/WO2014133022A1/ja active Application Filing
- 2014-02-26 AU AU2014221775A patent/AU2014221775B2/en not_active Ceased
- 2014-02-26 ES ES14756740.8T patent/ES2685025T3/es active Active
- 2014-02-26 LT LTEP14756740.8T patent/LT2963043T/lt unknown
- 2014-02-26 MX MX2015010741A patent/MX362920B/es active IP Right Grant
- 2014-02-26 US US14/190,356 patent/US9458176B2/en active Active
- 2014-02-26 BR BR112015020545A patent/BR112015020545A2/pt active Search and Examination
- 2014-02-26 RU RU2015135967A patent/RU2659219C2/ru active
- 2014-02-26 UA UAA201508269A patent/UA114950C2/uk unknown
- 2014-02-26 EP EP14756740.8A patent/EP2963043B1/en active Active
- 2014-02-26 HU HUE14756740A patent/HUE040219T2/hu unknown
-
2015
- 2015-08-06 IL IL240402A patent/IL240402A/en active IP Right Grant
- 2015-08-26 PH PH12015501878A patent/PH12015501878A1/en unknown
- 2015-08-26 CL CL2015002391A patent/CL2015002391A1/es unknown
-
2016
- 2016-05-16 HK HK16105614.7A patent/HK1217697A1/zh not_active IP Right Cessation
-
2018
- 2018-08-23 HR HRP20181349TT patent/HRP20181349T1/hr unknown
- 2018-08-23 CY CY20181100881T patent/CY1121231T1/el unknown
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