KR910000703A - 테트라졸 자극성 아미노산 수용체의 길항물질 - Google Patents

테트라졸 자극성 아미노산 수용체의 길항물질 Download PDF

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Publication number
KR910000703A
KR910000703A KR1019900008930A KR900008930A KR910000703A KR 910000703 A KR910000703 A KR 910000703A KR 1019900008930 A KR1019900008930 A KR 1019900008930A KR 900008930 A KR900008930 A KR 900008930A KR 910000703 A KR910000703 A KR 910000703A
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KR
South Korea
Prior art keywords
tetrazol
antagonists
amino acid
acid receptors
stimulating amino
Prior art date
Application number
KR1019900008930A
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English (en)
Inventor
레슬리 오른스타인 포울
Original Assignee
리로이 휘테커
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 리로이 휘테커, 일라이 릴리 앤드 캄파니 filed Critical 리로이 휘테커
Publication of KR910000703A publication Critical patent/KR910000703A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

내용 없음

Description

테트라졸 자극성 아미노산 수용체의 길항물질
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 시스-(-)-4[(1(2)H-테트라졸-5-일)메틸]-2-피페리딘 카복실산 또는 그이 약제학적으로 허용가능한 염.
  2. 하나이상의 약제학적으로 허용가능한 담체, 부형제 또는 희석제와 혼합된, 활성성분으로서의 제1항에서 특허청구된 화합물, 또는 그의 약제학적으로 허용가능한 염을 포함하는 약제학적 제제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900008930A 1989-06-26 1990-06-18 테트라졸 자극성 아미노산 수용체의 길항물질 KR910000703A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/371,568 US4968678A (en) 1988-02-19 1989-06-26 Tetrazole excitatory amino acid receptor antagonists
US371568 1989-06-26

Publications (1)

Publication Number Publication Date
KR910000703A true KR910000703A (ko) 1991-01-30

Family

ID=23464503

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900008930A KR910000703A (ko) 1989-06-26 1990-06-18 테트라졸 자극성 아미노산 수용체의 길항물질

Country Status (17)

Country Link
US (1) US4968678A (ko)
EP (1) EP0405834A3 (ko)
JP (1) JPH0348679A (ko)
KR (1) KR910000703A (ko)
CN (1) CN1028024C (ko)
AU (1) AU621498B2 (ko)
CA (1) CA2019167A1 (ko)
FI (1) FI903183A0 (ko)
HU (1) HU206339B (ko)
IE (1) IE902288A1 (ko)
IL (1) IL94777A (ko)
MX (1) MX21219A (ko)
NZ (1) NZ234109A (ko)
PH (1) PH26905A (ko)
PT (1) PT94447B (ko)
RU (2) RU1833385C (ko)
ZA (1) ZA904717B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA891113B (en) * 1988-02-19 1990-10-31 Lilly Co Eli Tetrazole excitatory amino acid receptor antagonists
US5594007A (en) * 1991-04-18 1997-01-14 Pfizer Inc. Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5196421A (en) * 1991-06-05 1993-03-23 Eli Lilly And Company Excitatory amino acid receptor antagonists in methods for the use thereof
EP0636130A1 (en) * 1992-04-15 1995-02-01 Merck Sharp & Dohme Ltd. Azacyclic compounds
US5192751A (en) * 1992-07-24 1993-03-09 Eli Lilly And Company Use of competitive NMDA receptor antagonists in the treatment of urinary incontinence
ATE311864T1 (de) * 1993-03-29 2005-12-15 Propan-1,3-disulphonsäure und deren pharmazeutisch akzeptable salze zur behandlung von amyloidosis
US20040208875A1 (en) 1995-03-15 2004-10-21 Queen's University At Kingston Method for treating amyloidosis
US5744483A (en) * 1994-01-31 1998-04-28 Pfizer Inc. Neuroprotective compounds
PT777652E (pt) * 1994-08-18 2003-11-28 Pfizer Derivados neuroptotectores de 3-(piperidinil-1)-croman-4.7-diol e de 1-(4-hidrofenil)-2-(piperidinil-1)-alcanol
US5880138A (en) * 1996-10-01 1999-03-09 Eli Lilly And Company NMDA receptor selective antagonists
WO2004032769A1 (en) * 2002-10-04 2004-04-22 Cook Urological, Incorporated Rigid extractor with wire basket
US8043303B2 (en) * 2002-10-04 2011-10-25 Cook Medical Technologies Llc Handle for interchangeable medical device
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
WO2005084564A1 (en) * 2004-02-27 2005-09-15 Cook Urological Incorporated Self-tensioning handle for endoscopic device
CA2900876A1 (en) 2004-12-22 2006-08-17 Bhi Limited Partnership Methods and compositions for treating amyloid-related diseases
TW200716088A (en) 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
EP1942811B1 (en) * 2005-11-03 2016-09-28 Cook Medical Technologies LLC Medical retrieval device with simultaneous articulation and extension or retraction
EP1968561B8 (en) 2005-12-22 2010-10-20 Kiacta Sàrl Treatment of diabetic nephropathy
CN106946748B (zh) 2006-10-12 2019-02-05 Bhi有限合资公司 递送3-氨基-1-丙磺酸的方法、化合物、组合物和载体
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536715A (en) * 1967-03-24 1970-10-27 Miles Lab 2-lower alkyl-5-(omega-(4-phenyl-1-piperazinyl) lower alkyl)-2h-tetrazoles
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids
PH23848A (en) * 1985-05-24 1989-11-23 Ciba Geigy Ag Certain phosphonic acids and derivatives
US4746653A (en) * 1986-02-28 1988-05-24 Ciba-Geigy Corporation Certain hetero phosphonic acid derivatives of 2-piperidine or 2-tetrahydropyridinecarboxylates and esters thereof which are useful for the treatment of disorders responsive to blockade of the NMDA receptor in mammals
EP0275820B1 (de) * 1986-11-21 1991-02-06 Ciba-Geigy Ag Ungesättigte Phosphonsäure und Derivate
ZA891113B (en) * 1988-02-19 1990-10-31 Lilly Co Eli Tetrazole excitatory amino acid receptor antagonists

Also Published As

Publication number Publication date
JPH0348679A (ja) 1991-03-01
PT94447A (pt) 1991-02-08
CN1028024C (zh) 1995-03-29
EP0405834A2 (en) 1991-01-02
CN1048385A (zh) 1991-01-09
EP0405834A3 (en) 1991-12-27
IL94777A0 (en) 1991-04-15
FI903183A0 (fi) 1990-06-25
HU903976D0 (en) 1990-11-28
RU1833385C (ru) 1993-08-07
ZA904717B (en) 1992-02-26
US4968678A (en) 1990-11-06
CA2019167A1 (en) 1990-12-26
IL94777A (en) 1994-05-30
HU206339B (en) 1992-10-28
IE902288L (en) 1990-12-26
NZ234109A (en) 1992-04-28
AU5780890A (en) 1991-01-03
RU2089546C1 (ru) 1997-09-10
AU621498B2 (en) 1992-03-12
PH26905A (en) 1992-12-03
MX21219A (es) 1993-11-01
PT94447B (pt) 1997-02-28
HUT54364A (en) 1991-02-28
IE902288A1 (en) 1991-01-16

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