KR20230082134A - Non-invasive drug delivery device for nerve block - Google Patents

Abstract

The present invention relates to a non-invasive nerve blocking drug delivery device, wherein the non-invasive nerve blocking drug supply device according to the present invention includes: a drug supply unit; a supply channel receiving the drug through the drug supply unit; and a catheter connected to each end of the supply channel and inserted into the abdominal wall of a recipient in the direction of the thickness of the abdominal wall to administer the drug. The insertion position of the catheter is set to a position corresponding to the sensory nerve associated with the surgical incision. According to the present invention, provided is the non-invasive nerve blocking drug supply device that can effectively prevent postoperative pain by non-invasively supplying the nerve blocking drug to a root portion of a nerve bundle connected to the surgical incision.

Description

Non-invasive drug delivery device for nerve block}

The present invention relates to a non-invasive nerve blocking drug supply device, and more particularly, to a non-invasive method for effectively preventing pain after surgery by non-invasively supplying a nerve block drug to the root of a nerve bundle connected to a surgical incision. It relates to a nerve blocking drug delivery device.

In general, a catheter is a medical catheter used to suck blood, hematoma, body fluid, etc. in the human body for examination or removal, or to inject drugs into the human body.

Depending on the site or purpose of use, these catheters include a urinary catheter for excretion of urine, bladder cleaning, and drug injection into the bladder, a balloon catheter used for cardiovascular expansion procedures, and a hiket inserted into a vein for drug injection and blood collection. There are many types, such as mannequin catheters, tracheal catheters used to remove foreign substances sucked into the trachea and oral cavity of newborns right after birth, and dental suction catheters used to suction and discharge blood and saliva generated during dental procedures. do.

On the other hand, recently, laparoscopic surgery replaces the existing open surgery and its use is gradually spreading. In the case of laparoscopic surgery, wounds are not large, but at least three to as many as five occur in various places on the abdomen.

This laparoscopic surgery has a smaller incision compared to the traditional invasive open surgery and can greatly reduce pain for the person being operated on, but still suffers from great pain for 48 to 72 hours after surgery.

Therefore, after surgery, the narcotic analgesic is directly administered into the blood vessel of the recipient or is administered through a patient controlled analgesia (PCA). However, since this method requires considerable attention to the dosage of the narcotic analgesic according to each patient's condition, there is a problem in that intensive management of a significant number of medical personnel is required to prevent medical accidents.

Recently, it is known that blockade of the transversus abdominis plane (transversus abdominis plane, hereinafter referred to as TAP block) pain nerve block is effective, which blocks the nerve that transmits abdominal pain after surgery using a local anesthetic. It is a control operation. In addition, pain caused by wounds during such surgery is transmitted to the brain via the spinal cord through the thin nerves present in the abdominal wall (see Fig. 2). It is a surgical procedure to block this neurotransmission process by administering a topical analgesic to the nerve.

Recently, various literatures have reported that TAP block is very helpful in relieving pain in patients after surgery. However, currently commercialized TAP block treatment poses several technical challenges as follows.

First, since most of the analgesics used are local anesthetics, the analgesic effect does not last for more than 6 hours, although there is a difference depending on the drug. In addition, considering that pain peaks at 48 to 72 hours after abdominal surgery, the analgesic effect of the current TAP block is very insufficient. If the TAP block is to be performed 2 or 3 times after surgery, the intramuscular injection must be repeatedly injected into the patient's side, which is another technical effort, pain, and risk of infection due to repeated injections.

Second, since most of the current TAP block procedures are performed under the assistance of ultrasound, the procedure is complicated. Therefore, the operator performing the TAP block must have ultrasound equipment and be familiar with ultrasound technology (see Fig. 3).

Accordingly, there is a demand for development of a catheter or device capable of continuously administering a drug for nerve block.

Korean Patent Publication No. 10-2008-0082594

Therefore, an object of the present invention is to solve such conventional problems, and to provide a non-invasive method that can effectively prevent pain after surgery by non-invasively supplying a drug for nerve block to the root of a nerve bundle connected to a surgical incision. It is to provide a nerve blocking drug supply device.

In addition, by injecting the drug through a plurality of injection nozzles formed along the longitudinal direction on the outer circumferential surface of the catheter, a non-invasive method capable of simultaneously blocking a plurality of sensory nerves disposed in the thickness direction of the abdominal wall (peritoneum, fascia, muscle and subcutaneous layer) It is to provide a nerve blocking drug supply device.

In addition, by providing a plurality of catheters having different lengths of the injection area in which a plurality of injection nozzles are formed, and selecting and combining any one catheter according to the thickness of the abdominal wall of the person to be treated or the distribution of sensory nerves, the drug is applied to some of the sensory nerves. It is an object of the present invention to provide a non-invasive nerve block drug supply device capable of preventing exposure of some injection nozzles to the abdominal cavity or to the outside of the skin layer.

In addition, by fixing the catheter to the skin layer of the recipient using the fixing part, it is possible to prevent the insertion position of the catheter from being arbitrarily changed, and to prevent the catheter from being easily bent at the interface with the skin layer. Non-invasive nerve block drug supply to provide the device.

The above object, according to the present invention, the drug supply unit; a supply passage through which the drug is delivered through the drug supply unit; and catheters respectively connected to ends of the supply passage and inserted into the abdominal wall of the person to be treated in the abdominal wall thickness direction to administer drugs, wherein the catheter is inserted into a position corresponding to a sensory nerve associated with the surgical incision. It is achieved by a non-invasive nerve block drug delivery device that is set.

Here, it is preferable that a plurality of supply passages are provided to administer drugs to a plurality of sensory nerves associated with at least one surgical incision.

In addition, the supply passage preferably includes a first tube connected to the drug supply unit, a branching unit connected to the first tube, and a plurality of second tubes connected to the branching unit, respectively.

In addition, it is preferable that a plurality of drug injection nozzles are formed on the outer circumferential surface of the catheter along the longitudinal direction so that each of the drugs can be supplied to a plurality of sensory nerves distributed in the thickness direction within the abdominal wall of the person to be treated.

In addition, the drug injection nozzle preferably supplies the drug to the sensory nerves located in the deep and superficial parts of the abdominal wall, respectively.

In addition, the injection area where the drug injection nozzle of the catheter is formed preferably has a length corresponding to the thickness of the abdominal wall of the person to be treated.

In addition, a plurality of the catheters are provided, and each catheter has a different length of the injection area, and among the plurality of catheters, one selected catheter having a spray area corresponding to the thickness of the abdominal wall of the person to be treated is connected to the supply passage. It is desirable to be connected.

In addition, it is preferable to further include; a fixing unit for fixing the catheter or the supply passage connected to the catheter to the skin layer of the abdominal wall.

In addition, the fixing part includes a cylindrical fixing guide having a first insertion hole into which the catheter can be inserted and a fixing cap coupled to the fixing guide and having a second insertion hole into which the catheter can be inserted. It is preferable that the coupling surface of the guide and the fixing cap is made of an inclined surface in close contact with each other, and the catheter is fixed in the first insertion hole while the first insertion hole is contracted by the combination of the fixing guide and the fixing cap.

In addition, it is preferable that the first insertion hole and the second insertion hole each have a shape open in the lateral direction.

In addition, it is preferable that the fixing part extends laterally from the lower end of the fixing guide and is tightly fixed to the skin layer of the abdominal wall.

According to the present invention, there is provided a non-invasive nerve blocking drug supply device capable of effectively preventing pain after surgery by non-invasively supplying a nerve block drug to the root of a nerve bundle connected to a surgical incision.

In addition, a non-invasive nerve blocking drug supply device capable of simultaneously blocking a plurality of sensory nerves disposed in the thickness direction in the abdominal wall by injecting the drug through a plurality of injection nozzles formed along the longitudinal direction on the outer circumferential surface of the catheter is provided.

In addition, by providing a plurality of catheters having different lengths of the injection area in which a plurality of injection nozzles are formed, and selecting and combining any one catheter according to the thickness of the abdominal wall of the person to be treated or the distribution of sensory nerves, the drug is applied to some of the sensory nerves. Provided is a non-invasive nerve block drug supply device capable of preventing exposure of some injection nozzles to the abdominal cavity or to the outside of the skin layer.

In addition, by fixing the catheter to the skin layer of the recipient using the fixing part, it is possible to prevent the insertion position of the catheter from being arbitrarily changed, and to prevent the catheter from being easily bent at the interface with the skin layer. Non-invasive nerve block drug supply device is provided.

1 is a view showing the mechanism of abdominal pain;
Figure 2 is a photograph showing the state of TAP block treatment using ultrasound equipment,
3 is a block diagram of a drug supply device for nerve block according to the present invention;
Figure 4 is an excerpted perspective view of the catheter shown in Figure 3;
5 is a view showing a plurality of catheters having different injection area lengths;
6 is an excerpted perspective view of the fixing part shown in FIG. 3;
7 is an exploded perspective view of the fixing part shown in FIG. 6;
8 is a view showing a state of use of the drug supply device for nerve block according to the present invention;
9 is a view showing the distribution of sensory nerves in the abdominal wall of the human body;
10 is a cross-sectional view of the catheter insertion portion shown in FIG. 8;
11 is a plan view of FIG. 10;
12 to 14 are images showing the procedure of the drug supply device for nerve block according to the present invention.

Prior to description, in various embodiments, components having the same configuration are typically described in the first embodiment using the same reference numerals, and in other embodiments, components different from those of the first embodiment will be described. do.

Hereinafter, a drug supply device for nerve block according to a first embodiment of the present invention will be described in detail with reference to the accompanying drawings.

Among the accompanying drawings, FIG. 3 is a configuration diagram of a drug supply device for nerve block according to the present invention, FIG. 4 is a perspective view of an excerpt of the catheter shown in FIG. 3, FIG. 5 is a view showing a plurality of catheters having different injection area lengths, FIG. 6 is an excerpted perspective view of the fixing part shown in FIG. 3, FIG. 7 is an exploded perspective view of the fixing part shown in FIG. 6, FIG. 8 is a view showing a state of use of the drug supply device for nerve block according to the present invention, and FIG. 9 is an abdominal wall of a human body FIG. 10 is a cross-sectional view of the catheter insertion portion shown in FIG. 8, and FIG. 11 is a plan view of FIG.

As shown in the drawings, the drug supply device for nerve block of the present invention can effectively prevent pain after surgery by non-invasively supplying the drug for nerve block to the root of the nerve bundle connected to the surgical incision, (110), a supply passage (120), a catheter (130) and a fixing part (140).

The chemical solution supply unit 110 stores the chemical solution and provides pressure for ejection of the chemical solution, and includes a chemical storage unit that stores the chemical solution, a pump that provides an automatic contraction function for ejection of the chemical solution, and a chemical solution by driving the pump. It may be configured to include a control unit for adjusting the ejection period, ejection amount, and the like. Here, the medicinal solution may include a local anesthetic such as lidocaine and ropivacaine and a substance for blocking nerve pain. In addition, a refilling device for filling the chemical solution may be connected to the chemical storage unit.

The supply passage 120 is connected to the chemical solution supply unit 110 and provides a passage for transporting the drug solution, and is configured to administer a plurality of drug solutions to a plurality of sensory nerves associated with at least one surgical incision. A passage may be provided. Specifically, the supply passage 120 includes a first tube 121 connected to the chemical liquid supply unit 110, a first branch part 122 connected to the first tube 121, and the first branch part ( 122) may be configured to include a plurality of second tubes 123 connected to each other.

In addition, the first tube 121, the first branch portion 122, and the second tube 123 are provided in plurality to minimize interfering with the activity of the subject and prevent crossing the surgical site, and the left and right sides of the subject The second branch part 124 which can be disposed on the right side and connects the plurality of first tubes 121 to supply the chemical solution to each of the plurality of first tubes 121, and the second branch part 124 ) and a supply tube 125 connecting the chemical solution supply unit 110 may be further included.

The first branch part 122 is provided with a chamber capable of accommodating drugs therein. Accordingly, as the drug supplied into the chamber through the first tube 121 maintains a constant pressure as a whole, the plurality of second tubes 123 connected to the first branch 122 each have an equal pressure and flow rate can supply the drug. Similarly, as the second branch 124 also has a chamber capable of accommodating the drug, the drug can be supplied to the plurality of first tubes 121 connected to the second branch 124 at equal pressure and flow rate, respectively. can

On the other hand, although not shown in the drawing, the second tube 123 may be provided with a control switch capable of adjusting the supply amount of the chemical solution.

The catheter 130 is connected to the second tube 123 of the supply passage 120 and is inserted into the abdominal wall of the user in the abdominal wall thickness direction, and is made of a tube of a soft material with one end closed, A plurality of injection nozzles 131 for ejecting the chemical solution are formed on the outer surface of the section inserted into the abdominal wall of the body.

Specifically, the catheter 130 is inserted and installed into the abdominal wall of the person to be treated in the thickness direction of the abdominal wall by withdrawing and removing the injection needle in a state where it is inserted into the abdominal wall together with the injection needle, and is installed from the drug supply unit 110. By discharging the supplied chemical solution through the plurality of injection nozzles 131 formed on the outer surface, the chemical solution can be supplied to each of a plurality of sensory nerves located in the abdominal wall.

For example, as shown in FIG. 8, most of the abdominal laparoscopic surgery is performed within a circle marked on the abdomen of the subject, so if the nerve block for the thoracoabdominal nerves (T7 to T11) and the rib cage (T12) is effectively performed, the pain after abdominal laparoscopic surgery is can be significantly reduced. Therefore, the insertion position of the catheter 130 is preferably set to a position corresponding to a sensory nerve associated with an incision for laparoscopic surgery formed in the abdomen of a subject. In this embodiment, eight catheters 130 have been described as being respectively inserted into the flanks around the abdomen, but are not limited thereto. It may be appropriately changed according to the number or location of incisions.

In particular, as shown in FIG. 9, the sensory nerves located in the abdominal wall of the human body are located between the skin layer (C) and the external oblique muscle (EOM), which are the surface portion of the abdominal wall, and between the internal oblique muscle (IOM) and the transverse abdominal muscle (TAM), which are deep in the abdominal wall. . Specifically, the intercostal nerve (Intercostal nerve, ICN) extends from the thoracic nerve that extends along the spine, extends between the transversus abdominis muscle (TAM) and the internal oblique muscle (IOM), and extends from the side of the body to the lateral skin branch ( It branches into the lateral cutaneous branch (LCB) and the anterior cutaneous branch (ACB). In addition, the lateral dermal branch (LCB) penetrates the internal oblique muscle (IOM) and the external oblique muscle (EOM) and extends forward between the external oblique muscle (EOM) and the skin layer (C) and the anterior branch (AB) and the posterior Branches into an extended posterior branch (PB). In addition, the anterior skin branch (ACB) penetrates the rectus abdominis muscle (RAM) and has a medial branch (MB) extending toward the center of the front of the abdomen between the rectus abdominis muscle (RAM) and the skin layer (C) and an lateral branch extending toward the side. (Lateral branch, LB). As such, the sensory nerves located in the abdominal wall are distributed in the surface of the abdominal wall (between the skin layer (C) and the external oblique muscle (EOM)) and the deep abdominal wall (between the internal oblique muscle (IOM) and the transversus abdominis muscle (TAM)), respectively. Therefore, it is also formed in the form of penetrating the muscle inside the abdominal wall.

Even if local analgesics are administered to the upper intercostal nerve (ACB) located between the internal oblique muscle (IOM) and transversus abdominis muscle (TAM) using the existing TAP block, pain transmitted through sensory nerves located on the abdominal surface cannot be blocked. Of course, in the process of performing the TAP block, the drug is added to the anterior branch (AB), posterior branch (PB), lateral branch (LB), or inner branch (MB) located between the external oblique muscle (EOM) and the skin layer (C). It can be administered, but due to the nature of the procedure involving ultrasound, it takes a lot of time to supply the drug to the sensory nerves distributed in various parts of the abdominal wall. There is the hassle of administering .

According to this embodiment, since a plurality of spray nozzles 131 are formed along the longitudinal direction on the outer surface of the catheter 130 as shown in FIG. A plurality of senses dispersed and disposed in the thickness direction within the abdominal wall of the person to be treated, such as supplying the drug solution to the sensory nerves (N) distributed in each part, as well as supplying the drug solution to the sensory nerves located in a form penetrating the abdominal wall. Since each of the nerves (N) can be supplied with a medicinal solution, a plurality of sensory nerves (N) that sense pain in the abdominal wall can be blocked at the same time.

In addition, since the abdominal wall has a different thickness depending on the body shape of the person to be treated or the site where the catheter 130 is inserted, when the area where the drug injection nozzle 131 is formed on the outer surface of the catheter 130 has a certain length, some The drug solution may not be delivered to sensory nerves distributed in the thickness direction within the abdominal wall at a body-shaped subject or a specific location, or some of the spray nozzles 131 may be exposed inside the abdominal cavity or outside the skin layer.

Therefore, in the present embodiment, as shown in FIG. 5, a plurality of catheters 130a, 130b, and 130c having different lengths in the injection area where the chemical injection nozzle 131 of the catheter 130 is formed are provided, and the catheter 130 is to be inserted. Configured to connect any one catheter 130 selected from among the plurality of catheters 130a, 130b, and 130c to the second tube 123 of the supply passage 120 according to the thickness of the abdominal wall or the distribution of sensory nerves. By doing so, it is possible to solve the problem that the chemical solution is not supplied to some of the sensory nerves or that some injection nozzles 131 are exposed to the inside of the abdominal cavity or to the outside of the skin layer.

On the other hand, the catheter 130 as described above may be fixed to the skin layer of the pisisulja by the fixing part 140.

The fixing part 140 is a cylindrical fixing guide 141 having a first insertion hole 141a into which the catheter 130 can be inserted, extending laterally from the lower part of the fixing guide 141 to be in close contact with the skin. A second insertion hole 143a into which the pad portion 142 and the catheter 130 can be inserted is formed and includes a fixing cap 143 coupled to the fixing guide 141.

The fixing guide 141 has a trapezoidal cross-section and has an inclined side surface, and a male screw 141b for screwing with the fixing cap 143 is formed on the outer circumferential surface.

The pad part 142 is made of a material such as non-woven fabric so as to be in close contact with the skin, and can be fixed to the skin by a double-sided adhesive or skin bonding bond. On the other hand, the pad part 142 may be fixed to the skin by a suture to provide a firm fixation force in a region with a lot of movement. To this end, the pad part 142 has a plurality of punch holes through which the suture can pass ( 142a) may be formed. The pad part 142 may be formed in a form extending horizontally from both sides of the lower end of the fixed guide 141, but is not limited thereto, and the shape of the pad part 142 varies according to the characteristics of the fixing position. can be changed to

The fixing cap 143 has a receiving groove into which the fixing guide 141 can be inserted is formed on the bottom surface, and the inner circumferential surface of the side wall in contact with the receiving groove is made of an inclined surface to correspond to the outer circumferential surface of the fixing guide 141. , a female screw 143b for screwing with the fixing guide 141 is formed on the inner circumferential surface.

Meanwhile, when the fixing guide 141 and the fixing cap 143 are coupled, the outer diameter of the fixing guide 141 is relative to the inner diameter of the fixing cap 143 so that the first insertion hole 141a can contract. It is preferable to set large as .

In particular, each of the first insertion hole 141a and the second insertion hole 143a may have a shape open in a lateral direction. In this way, when the first insertion hole 141a and the second insertion hole 143a have a laterally open shape, the catheter 130 in a state where the fixing guide 141 and the fixing cap 143 are inserted into the abdominal wall. ) can be easily combined.

In the fixing part 140 configured as described above, as the coupling surfaces of the fixing cap 143 and the fixing guide 141 are each made of an inclined surface, the first insertion hole 141a of the fixing guide 141 and the fixing cap When the fixing cap 143 is screwed to the fixing guide 141 while the catheter 130 is coupled to the second insertion hole 143a of (143), the catheter ( 130) may be fixed in the first insertion hole 141a. If the ear pad part 142 is fixed to the skin using an adhesive or a suture, it is possible to prevent the insertion position of the catheter 130 from being arbitrarily changed. In addition, as shown in FIG. 11, when the first insertion hole 141a and the second insertion hole 143a are displaced from each other in a state where the fixing cap 143 is screwed to the fixing guide 141, the catheter 130 ) can be prevented from being arbitrarily separated through the side opening in the state of being inserted into the first insertion hole 141a and the second insertion hole 143a.

When the catheter 130 is fixed through the fixing part 140 as described above, the catheter 130 is firmly fixed and supported to prevent the catheter 130 from moving arbitrarily, and the catheter 130 ) can be prevented from being easily broken at the boundary with the skin layer.

Meanwhile, in this embodiment, the catheter 130 has been described as being fixed to the fixing part 140, but it will also be possible to fix the second tube 123 to which the catheter 130 is connected.

For example, when an incision for laparoscopic surgery is formed in the abdomen of a person to be operated on, as shown in FIG. 12 , a camera for laparoscopic surgery may be inserted through the incision for laparoscopic surgery and the inside of the abdominal wall may be observed as a camera image.

In this state, when the catheter of the present embodiment is inserted into the part of the subject's side where the sensory nerve associated with the incision is located, the insertion end of the catheter penetrates the abdominal wall inside the subject's abdominal wall as shown in FIG. It can be observed directly through the image obtained through the camera.

Subsequently, as shown in FIG. 14, by pulling the catheter penetrating the abdominal wall of the person to be treated while observing the camera image, the insertion end of the catheter can be positioned within the abdominal wall.

As described above, according to the present embodiment, since the insertion position of the catheter can be determined while directly observing the insertion state of the catheter inside the abdominal wall of the operator using the endoscopic camera for laparoscopic surgery, the procedure is very simple compared to the conventional TAP block method. can provide

Subsequently, as described above, the catheter may be fixed to the skin of the person to be treated using the fixing part, and the drug solution may be supplied to each of the plurality of sensory nerves located in the abdominal wall by supplying the drug to the catheter through the drug supplying part.

The scope of the present invention is not limited to the above-described embodiments, but may be implemented in various forms of embodiments within the scope of the appended claims. Anyone with ordinary knowledge in the art to which the invention pertains without departing from the subject matter of the invention claimed in the claims is considered to be within the scope of the claims of the present invention to various extents that can be modified.

110: drug supply unit, 120: supply passage, 121: first tube,
122: first branch, 123: second tube, 124: second branch,
125: supply tube, 130: catheter, 131: injection nozzle,
132: injection area, 140: fixed part, 141: fixed guide,
141a: first insertion hole, 141b: male screw, 142: pad part,
142a: punch hole, 143: fixed cap, 143a: second insertion hole,
143b: female thread,

Claims (11)

drug supply unit;
a supply passage through which the drug is delivered through the drug supply unit; and
A catheter connected to the end of the supply passage and inserted into the abdominal wall of the person to be treated in the abdominal wall thickness direction to administer the drug;
A non-invasive nerve block drug supply device in which the insertion position of the catheter is set to a position corresponding to a sensory nerve associated with a surgical incision. According to claim 1,
The non-invasive nerve blocking drug supply device having a plurality of supply passages provided to administer drugs to each of a plurality of sensory nerves associated with at least one surgical incision. According to claim 2,
The supply passage includes a first tube connected to the drug supply unit, a branching unit connected to the first tube, and a plurality of second tubes connected to the branching unit, respectively. According to claim 1,
On the outer circumferential surface of the catheter, a plurality of drug injection nozzles are formed along the longitudinal direction to supply drugs to each of the plurality of sensory nerves distributed in the thickness direction in the abdominal wall of the person to be treated. Non-invasive nerve block drug supply device. According to claim 4,
The drug injection nozzle is a non-invasive nerve blocking drug supply device for supplying drugs to sensory nerves located in the deep and superficial parts of the abdominal wall, respectively. According to claim 4,
Non-invasive nerve block drug supply device having a length corresponding to the thickness of the abdominal wall of the person to be treated. According to claim 6,
A plurality of catheters are provided, each catheter has a different length of the injection area, and among the plurality of catheters, one selected catheter having a spray area corresponding to the thickness of the abdominal wall of the person to be treated is connected to the supply passage Non-invasive nerve block drug delivery device. According to claim 1,
A non-invasive nerve block drug supply device further comprising a fixing unit for fixing the catheter or the supply passage connected to the catheter to the skin layer of the abdominal wall. According to claim 8,
The fixing part includes a cylindrical fixing guide having a first insertion hole into which the catheter can be inserted and a fixing cap coupled to the fixing guide and having a second insertion hole into which the catheter can be inserted,
The coupling surface of the fixed guide and the fixed cap is made of an inclined surface that closely adheres to each other, and the first insertion hole is contracted by the combination of the fixed guide and the fixed cap, and the catheter is fixed in the first insertion hole for non-invasive nerve block drug supply. Device. According to claim 9,
The first insertion hole and the second insertion hole are non-invasive nerve block drug supply device each having a laterally open shape. According to claim 9,
The non-invasive nerve block drug supply device further comprising a pad portion extending laterally from the lower end of the fixing guide and tightly fixed to the skin layer of the abdominal wall.

Images