KR102574775B1 - A method for fabricating orally disintegrating film containing extract pupae of male bees - Google Patents

Abstract

The present invention provides a method for manufacturing an ODF using a functional natural gel-type food composition, and in particular, manufacturing an ODF with a high yield in a short period of time by performing several processes as a continuous process in a single line. The method comprises the steps of: (a) preparing an extract of pupae of male bees (S10); (b) preparing an ODF composition using beekeeping products including the extract of pupae of male bees obtained in step (a) (S20); and (c) manufacturing an ODF using the ODF composition prepared in step (b) (S30). The step (c) includes the steps of: (c1) putting the composition into an ODF manufacturing machine and casting the ODF composition into a film of a thickness (S31); (c2) drying the same with hot air at a temperature of 60-70℃ after step (c1) (S32), wherein the same is dried so that the moisture content is about 4-10%; (c3) performing a vision inspection after step (c2) (S33); marking defective products by punching or the like (S34); (c4) sealing the same with an outer film after step (c3) (S35); (c5) cutting the same into an appropriate size through printing and slitting (S36) after step (c4) (S38). The processes of steps (c1)-(c5) are performed as a continuous process in a single line. Therefore, a jelly-type food composition as a new food can be provided.

Description

ODF manufacturing method using beekeeping products containing drone pupa extract {A method for fabricating orally disintegrating film containing extract pupae of male bees}

The present invention relates to a method for manufacturing an Orally Disintegrating Film (ODF), and more particularly, to a method for manufacturing ODF using a beekeeping product including a drone pupa extract.

Modern people's eating habits are increasingly westernized, and as the standard of living increases and interest in health increases, people are not satisfied with snacks that simply soothe hunger as in the past, but they are looking for food that can satisfy them in terms of health. . Therefore, there is a demand for the development of snacks that are familiar to people and can be eaten easily and can reinforce the health aspect.

Among them, the gel-type food is a semi-solid favorite food in which a gelling agent is mixed with the target food and molded and coagulated, and is made using various gelling agents such as pectin, agar, gelatin, and carrageenan. Gel food is highly preferred due to its unique physical properties, and is attracting attention as a food for infants and the elderly due to its soft and easy-to-melt texture.

In addition, the consumption pattern of snacks is also changing in the form of preferring to make them easily and easily in small quantities in line with the trend of aging and nuclear families. In line with this trend, it is necessary to focus on producing more diverse and competitive processed products by identifying new requirements of consumers and applying new processing technologies to products.

Premix is a product made for easy cooking at home. It consists of a variety of products, from frying powder or frying powder to confectionery and baking powder such as hotteok, hot cake, and cookies. As well-being emerges as a trend in these premixes, organic and healthy premix products are showing steady growth and gaining popularity. In addition, as the home-made culture of making and eating food with one's own hands spreads, premix products made by large corporations are becoming organic and health functional ingredients as more consumers want to eat safe food even though the price is high in line with the recent well-being trend in the market. The release of various well-being premix products, such as differentiated premix, is spreading.

As such, the demand for developing well-being desserts having high preference and excellent physical properties is rapidly increasing, and in particular, the need for developing well-being snacks containing a large amount of physiological functional ingredients is increasing.

On the other hand, honeybee drone pupas, which were used for mating purposes with queen bees in beekeeping farms and discarded, are classified as disgusting food in Korea and their edible value is not widely known.

In general, in beekeeping farms, male bees are used only for mating with queen bees, and until recently, their use value has been very insignificant. Recently, some farms have been training drones for eco-friendly control of bee mites or for mating to preserve excellent species, but most farms have not yet found a way to use the nurtured drones, so most of them are discarded. there is.

In addition, drone pupae are excellent foods with high protein content, excellent composition of essential amino acids, and various pharmacological effects such as relieving hangover, but high-protein pupae that are not hygienically processed are likely to deteriorate easily in the distribution process. Since it is high, there are many difficulties in commercialization, and it is not widely used by consumers because of the morphological aversion of raw materials, so its utilization as food is very insignificant.

However, drone pupae have the advantage of not having venom glands like worker bees in terms of toxicity, and are recognized as new food raw materials by the Ministry of Food and Drug Safety and Rural Development Administration in 2020, and are evaluated as having high utilization value as new food resources. However, it is expected to be a new source of income for beekeepers in difficult situations where honey production is decreasing due to climate change and industrialization. However, research on drone pupae as a food material is still insignificant.

Therefore, there is a demand for developing materials that can replace conventional materials to solve the above-mentioned conventional problems, improve people's health, form a health-oriented food culture, and increase demand for natural materials.

Honey (natural honey) can be defined as a thick sweet-tasting liquid that bees carry plant nectar or other sugary water, process it, and store it in the beehive. Honey has different colors, fragrances, tastes, and ingredients depending on the type of flower, but in general, sugar accounts for 83% and water for 17%. Contains enzymes, etc.

Black garlic is garlic aged and fermented under certain conditions of temperature and humidity. It is black garlic that is converted into a substance called S-allylcysteine by inhibiting the production of allicin from allicin in raw garlic and aging it. . As the content of allicin decreases during the aging process, the astringent and spicy tastes decrease, increasing sweetness, reducing gastrointestinal disorders, and reducing residual odor, helping to consume garlic.

Compared to raw garlic, black garlic has a higher content of SOD (superoxide dismutase), which removes active oxygen, and S-allylcysteine and S-allyl-mercapto-cysteine, which are antioxidants that do not exist in raw garlic. and a large amount of polyphenols.

Dragon fruit is a cactus fruit belonging to the Cactaceae family Hylocereus sp., and is known as pitaya, pitahaya, pitahaya, and pitaya roja. It is called a given name. The potassium content per 100g of flesh is 272mg, which is superior to apples or pears, as well as phosphorus, magnesium, calcium, iron, zinc, sodium, carotene, soluble dietary fiber, carbohydrates, protein, lipids, vitamin C, vitamin B1, and vitamin B2. It is rich in minerals and antioxidants that are beneficial to the human body, such as vitamin B3. The sugar content is 16-18 Brix (a unit representing sugar content), which is higher than apples (8-16 Brix), peaches (7-15 Brix), and tangerines (7-16 Brix).

On the other hand, jelly belongs to candies in the Korean Food Codex, and is defined as a solid state without fluidity that is concentrated and molded by adding other foods or food additives to sugars or sugar alcohols and gelling agents as raw materials. In general, jelly is prepared by mixing sugar and a gelling agent in fruit and vegetable juice, concentrating, and molding, and is a saccharide favorite food containing around 20% water content. Jelly can impart various textures depending on the type of gelling agent capable of binding moisture.

In addition, consumers have recently tended to prefer jellies prepared using functional food raw materials rather than simple jellies, and the manufacturing raw materials are also being upgraded and diversified.

Jelly prepared using functional food ingredients include grapes, Schisandra chinensis, ginseng, peach, ginger, sipjeondaebo, melon, noni, mulberry leaf, cordyceps, mulberry, and mango, and studies on sensory, physical, and physicochemical properties have been reported. has been

As such, research on the functional aspect is being actively conducted, but research on the texture and taste according to the properties of the jelly is somewhat insufficient in manufacturing jelly as a functional food. It is necessary to develop products that can increase

On the other hand, since oral disintegrating tablets (ODT) for children, the elderly, and critically ill patients who cannot swallow tablets, which is a disadvantage of tablets, were developed and marketed in the late 1990s, various ODT preparations have been developed and commercialized. In Korea, several pharmaceutical companies obtained patents and attempted commercialization. After the commercialization of ODT, a more advanced film formulation (ODF: oral disintegrating film dosage) was attempted, and in the early 2000s, innocent (USA) released a cold medicine as ODF for the first time.

Since then, ODF has been attempted to be applied to various purposes. The four core technologies of ODF administered through the oral cavity or oral mucosa include the solubility control technology of a quick-dissolving agent, the molding technology of a polymer containing API and inactive ingredients, the film production technology, and the bitter taste masking technology.

Among them, the bitter taste concealment technology due to dissolution in the mouth of API (Active Pharmaceutical Ingredients) is confirmed that the aftertaste of the bitter taste of the API can be effectively concealed by delaying the sweetness profile over time by concurrently injecting high-intensity sweeteners including stevioside. did In the case of masking technology, coating of API, adsorption to cyclodextrin and ion exchange resin, concealment by masking agents such as fragrance, inorganic salt and polymer are traditionally common, but our method is competitive in terms of economic efficiency and simplicity. I think there is.

On the other hand, as the above specific ODF manufacturing method, the same method as in FIG. 1 is disclosed, which will be briefly described.

First, the composition for ODF is synthesized, dried for about one day, first aged for another day, then slitted, second aged for another day, and then cut to an appropriate size. , packaging and printing processes before shipment.

However, since each process is performed in a separate and independent facility in the above method, it takes about 1 day for each process of composition synthesis, drying, primary aging, slitting, secondary aging and packaging, and cutting ) and the printing process takes about 1 day, so it takes a long time of about 7 days in total, and since each is performed separately in a separate and independent space, there is a problem that the yield is inevitably low.

Republic of Korea Patent Publication No. 2003-0078107

Under these circumstances, the present inventors have made intensive research efforts to solve the above-mentioned conventional problems and to develop snacks, particularly gel-type foods, with improved texture, flavor and flavor while considering the health of purchasers. As a result, the present inventors utilized a premix including drone pupa extract, honey, black garlic extract, and dragon fruit powder to prepare a functional ODF film with improved texture and flavor while being beneficial to health by balancing nutritional components, thereby achieving the present invention. completed.

Accordingly, one object of the present invention is to provide a functional natural gel-type food composition containing a drone pupal extract, honey, black garlic extract, and dragon fruit powder.

Another object of the present invention is to provide a premix comprising a drone pupa extract, honey, black garlic extract, and dragon fruit powder, and further mixing at least one selected from the group consisting of gums and flavoring agents. .

In addition, another object of the present invention is to manufacture an ODF film using a functional natural gel-type food composition, but in particular, to provide a high-yield ODF manufacturing method in a short time by performing several processes in a continuous process in one line to provide a way.

An ODF manufacturing method using beekeeping products containing a drone pupa extract according to the present invention is an ODF manufacturing method using a beekeeping product including a drone pupa extract, comprising the steps of (a) preparing a drone pupa extract (S10); (b) preparing a liquid composition for preparing ODF using beekeeping products containing the drone pupa extract obtained in step (a) (S20); and (c) preparing an ODF film using the ODF composition solution prepared in step (b) (S30); Including, wherein the step (a) includes (a1) the step of thawing the frozen drone pupae (S11), and (a2) washing the drone pupae thawed in the step (a1) with washing water, After the step (S12) of the selection process of raw materials to remove foreign substances using a sieve of a certain mesh, (a3) after (a2), the washed drone pupa is frozen at -30 ~ 45 ° C and then vacuum pressure 300 torr ~ 500 torr in a freeze dryer Freeze-drying for 15 to 24 hours under the condition, but freeze-drying so that the moisture content after drying is 4% or less (S13), and (a4) put the dried material in the step (a3) into a grinder and grind it to a size of 50 to 100 mesh Grinding step (S14) and (a5) mixing 75 to 85 parts by weight of 70% ethanol with 100 parts by weight of the drone pupa crushed in step (a4), and extracted for 4 to 8 hours at a temperature of 40 to 60 ° C. Step (S15) and (a6) after extraction in step (a5), concentrating until the soluble solids content (brix) of the extract is 60 to 70 brix under vacuum pressure of 300 torr to 500 torr (S16) including, In the step (b), (b1) 11 to 13 parts by weight of pullulan and 9 to 11 parts by weight of modified starch, 0.8 to 1.5 parts by weight of propylene glycol and 0.8 to 1.5 parts by weight of glycerin, as a beekeeping product containing a drone pupa extract 9 to 11 parts by weight of drone pupa extract, 13 to 15 parts by weight of honey, 2.5 to 3.5 parts by weight of propolis, 4 to 6 parts by weight of pollen extract, and 40 to 50 parts by weight of purified water. Essential ingredient mixing step (S21) for preparing a natural gel-type food composition, and (b2) 1 to 30% by weight of the 'functional natural gel-type food composition containing a drone pupa extract' prepared in step (b1), water-soluble polymer 35 ~ 50% by weight, 0 to 20% by weight of plasticizer, 3 to 6% by weight of sweetener, 2 to 6% by weight of salivary stimulant, and the balance of surfactant, flavor and colorants, mixed to form a composition solution for preparing the final ODF. Material addition step (S22) and (b3) after preparing the ODF composition solution in step (b2), removing air bubbles in the composition solution through a degassing process for 30 to 40 minutes using a vacuum defoamer (S23) The step (c) includes (c1) the step (S31) of putting the composition solution for preparing the ODF into an ODF maker and casting it into a film having a certain thickness (S31), (c2) after the step (c1) , Drying with hot air at a temperature of 60 ~ 70 ℃, drying so that the moisture content is 4 ~ 10% (S32), (c3) after the step (c2), vision inspection is performed (S33), a defective product Marking by silver punching (S34), (c4) after the (c3) step, sealing with the outer film (S35), (c5) after the (c4) step, printing and slitting ) through the process (S36), the step of cutting to an appropriate size (S37), and (c6) after the step (c5), sterilization using a UV lamp with a wavelength of 100 to 280 nm to prevent contamination of the surface of the completed ODF film. It consists of a step (S38) of packaging while performing, and it is characterized in that all the processes of the steps (c1) to (c5) are made as a continuous process in one line.

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The gel-type food composition of the present invention is a functional natural gel-type food composition that can help improve health functions by containing drone pupa extract, honey, black garlic extract, dragon fruit powder, flavoring agent, gum, and purified water, and includes drone pupa extract, honey Provided is a jelly-type food composition as a new food with enhanced texture and flavor, which can contribute to the promotion of national health by conveniently ingesting pharmacological and nutritional components of black garlic essence and dragon fruit powder. In addition, the development of such a functional natural gel-type food composition can be used as a healthy snack that can replace fast food or instant food, and promotion of consumption of drone pupa extract, honey, black garlic extract, and dragon fruit powder is a new source of income for beekeepers. expected to be

In particular, the ODF produced by the ODF manufacturing method using the beekeeping product containing the drone pupa extract of the present invention is an advanced formulation of a tablet or capsule traditionally administered through the oral cavity, and has fast disintegration and rapid dissolution in the form of a thin film. 1) It is convenient because it can be taken without water, 2) It is easy to administer to patients who have difficulty taking tablets and capsules, such as children and the elderly, and 3) It is a film-type formulation that can be carried around in a wallet and is not restricted by when and where to take it It can be taken anywhere, anytime. In addition, 4) the bitter taste is properly concealed, so the medication compliance is good, 5) the manufacturing cost is not significantly higher than that of tablets or capsules, 6) the oral mucosal adhesion can be controlled, so the rapid dissolution and mucosal adhesion can be controlled to prevent spitting out. 7) It is possible to design quick-dissolving and fat-soluble formulations by controlling the solubility of the film. Additionally, 8) bioavailability can be increased by using IODDS (intra oral drug delivery system) technology.

Above all, according to the ODF manufacturing method using the beekeeping product containing the drone pupa extract of the present invention, an ODF film is prepared using a functional natural gel-type food composition, but in particular, to provide a high-yield ODF manufacturing method in a short time there is

The following drawings attached to this specification illustrate a preferred embodiment of the present invention, and together with the detailed description of the present invention serve to further understand the technical idea of the present invention, the present invention is limited to those described in the accompanying drawings. It should not be construed as limiting.
1 shows the overall flow of a conventional ODF manufacturing method.
Figure 2 shows the overall flow of the ODF manufacturing method using the beekeeping product including the drone pupa extract according to the present invention.
Figure 3 is a schematic diagram of the casting process of Figure 2;
Figure 4 is a schematic diagram of the inspection (inspection) process of Figure 2;
Figure 5 is a schematic diagram of the printing (printing) and slitting (slitting) process of FIG.
6 is a schematic diagram of a packing process of FIG. 2;
7 is a detailed flow chart of an ODF manufacturing method using beekeeping products including a drone pupa extract according to the present invention.

Hereinafter, preferred embodiments according to the present invention will be described in detail with reference to the accompanying drawings.

Below, the embodiments of the present invention will be described in detail with reference to the drawings, but the presented embodiments are illustrative for a clear understanding of the present invention, and the present invention is not limited thereto.

(First embodiment)

First, before describing the ODF manufacturing method using the beekeeping product including the drone pupa extract according to the first embodiment of the present invention, the composition for preparing ODF and the preparation of ODF composition food will be described.

Functional natural gel-type food composition solution containing drone pupa extract

First, the composition for preparing ODF according to the first embodiment of the present invention will be described. Prior to that, a functional natural gel-type food composition containing a male bee pupa extract, honey, and the like is prepared.

In addition to this, a functional natural gel-type food composition liquid containing black garlic essence, dragon fruit powder, gum, flavoring agent and purified water is provided.

That is, the functional natural gel-type food composition of the present invention contains 500 to 2000 parts by weight of drone pupal extract, 200 to 600 parts by weight of honey, 30 to 60 parts by weight of black garlic essence, 30 to 60 parts by weight of dragon fruit powder, and 50 to 100 parts by weight of gum. , 1 to 30 parts by weight of a flavoring agent, and 1000 to 3000 parts by weight of purified water.

In addition, other beekeeping products such as royal jelly, pollen and/or propolis may be added in appropriate amounts.

The drone pupal extract included in the functional natural gel-type food composition of the present invention may be used in liquid or solid form as long as it can achieve the desired effect, and a powdered drone pupal extract is preferably used.

The amount of drone pupal extract contained in the gel food composition of the present invention is preferably 500 to 2000 parts by weight, more preferably 700 to 1400 parts by weight, and most preferably 1400 parts by weight. If the content of the drone pupa extract in the present composition is lower than 500 parts by weight, the efficacy of the drone pupa extract may be lowered, and if it is higher than 2000 parts by weight, the taste of the food may be deteriorated.

As the saccharides included in the functional natural gel-type food composition of the present invention, saccharides commonly used in food may be used. Specifically, one selected from starch syrup, honey, sugar alcohol, oligosaccharide, white sugar, and mixtures thereof may be preferably used. For flavor of taste in the composition, it is preferable to use sugars including honey.

Honey is preferably used within a range that does not significantly affect taste and texture, and is preferably added in an amount of 200 to 600 parts by weight.

In addition, the functional natural gel-type food composition of the present invention may additionally contain at least one saccharide selected from the group consisting of monosaccharides, disaccharides, sugar alcohols, oligosaccharides and dextrin, wherein the monosaccharides and disaccharides are glucose, fructose, allul at least one selected from the group consisting of sugar, lactose, maltose, isomaltose, turanose and trehalose; the sugar alcohol is at least one selected from the group consisting of xylitol, sorbitol, maltitol, lactitol, inositol, and erythritol; Alternatively, the oligosaccharide is at least one selected from the group consisting of fructooligosaccharide, maltooligosaccharide, isomaltooligosaccharide, galactooligosaccharide and soybean oligosaccharide.

As the black garlic extract included in the functional natural gel-type food composition of the present invention, black garlic extract prepared by any method known in the art may be used as long as the desired effect can be achieved.

The amount of black garlic extract contained in the gel-type food composition of the present invention is preferably 30 to 60 parts by weight. If the content of the black garlic extract of the present composition is lower than 30 parts by weight, the efficacy of the black garlic extract may be lowered, and if it is higher than 60 parts by weight, the taste of the food may be deteriorated.

Dragon fruit powder included in the functional natural gel-type food composition of the present invention may be prepared by any method known in the art, as long as the desired effect can be achieved.

The amount of dragon fruit powder contained in the gel-type food composition of the present invention is preferably 30 to 60 parts by weight. If the black garlic essence content of the present composition is lower than 30 parts by weight, there may be a problem in that the efficacy of dragon fruit powder is lowered, and if it is higher than 60 parts by weight, there may be a problem of deteriorating the taste of food.

The flavoring agent of the present invention may be used alone or in combination with any natural flavoring agent or synthetic flavoring agent as long as it can achieve the effect of enhancing the flavor among sensory elements, and herbs, herb extracts, fruits, fruit extracts and It may be at least one selected from the group consisting of citrus oil, and the flavor included in the gel-type food composition of the present invention is a mixed fruit flavor, and the amount is preferably 1 to 30 parts by weight.

the herb is at least one selected from the group consisting of spearmint, hibiscus, lemon balm, peppermint, stevia, rosemary, lavender, rooibos, lemongrass, rose, rosehip, marigold, ginger and St. John's wort; The herbal extract is at least one dry substance selected from the group consisting of spearmint, hibiscus, lemon balm, peppermint, stevia, rosemary, lavender, rooibos, lemongrass, rose, rosehip, marigold, ginger and St. John's wort, concentrate or It may be a processed product of a concentrate.

the fruit is at least one selected from the group consisting of peaches, mangoes, bananas, raspberries, strawberries, pineapples, oranges, lemons, citrons, and apples; The fruit extract may be at least one dried product selected from the group consisting of peaches, mangoes, bananas, raspberries, strawberries, pineapples, oranges, lemons, citrons, and apples, concentrates, or processed products of concentrates.

In this specification, 'concentrate' may include all products produced by concentrating a target material or extracting only necessary components from the target material, and the form may be in powder form ('concentrated powder' or 'extracted powder') or liquid It may be in the form ('concentrate' or 'extract'), but is not particularly limited thereto.

The gel-type food composition according to the present invention includes gum, and thus can impart appropriate strength and hydrophobicity, particularly strength and hydrophobicity to the extent that it can be easily destroyed with the tongue when ingested. If the content is out of the appropriate range, the physical properties of a gel-type food that reduces bitterness or has good intake convenience are not realized, and it causes a bitter taste to be felt better and increases the water runoff, which is the cause of the inconvenience of flowing down when ingested, and product production When the gel is formed, there is a possibility that the production rate is lowered and the loss rate of the finished product is increased due to problems of temperature and viscosity at which the gel is formed.

As the gums used in the present invention, gums generally used in jelly production can be selectively used, but it is not limited to any specific gum. Gum that can be used for this is at least one gum selected from natural gums such as agar, xanthan gum, locust bean gum, gelatin, carrageenan, guar gum, gellan gum, alginic acid, pectin, psyllium husk, and gum arabic. Although the present invention is not limited to any specific gum, in the embodiment of the present invention, some gums (0.6% by weight of agar, 0.4% by weight of carrageenan, 0.3% by weight of xanthan gum and 0.1% by weight of locust bean gum) for convenient manufacturing and use A mixed gum previously prepared by mixing was used.

The mixed gum included in the gel-type food composition of the present invention acts as a gelling agent to help disperse the components in the composition of the present invention and to control the flowability during molding.

In the present invention, 50 to 100 parts by weight of natural or synthetic modified gums alone or in combination may be used, preferably 85 parts by weight. Here, food additives such as sweeteners, acidulants, flavoring agents, and texture improvers may be additionally included to mask metallic salty and astringent tastes and improve taste and aroma, and natural pigments may be added to color, Preservatives may be added to prolong shelf life.

Purified water of the present invention serves as a solvent, and may include 1000 to 3000 parts by weight.

Here, when the purified water is less than 1000 parts by weight, the texture of the food is not good, and when it exceeds 3000 parts by weight, the shape of the food is not well maintained.

The functional natural gel-type food of the present invention is gummy jelly or water jelly.

Gummy jelly is a formulation made by pouring a certain amount of a jelly mixture in a liquid state into a starch mold, aluminum mold, or silicon mold and hardening it. am.

In addition, it is the smallest in size and has the highest elasticity among jelly products, and the jelly produced as above is generally packaged in a bottle or the like and has a unique elastic texture such as dried fruit.

In addition, even though water jelly is prepared with the same amount of thickened polysaccharide, the amount of water added is relatively high, so the physical properties are soft, so it can be said to be an intermediate form between liquid beverage and gummy jelly. It can be eaten by filling it on the back or using a spoon or other utensil depending on the packaging type.

The gel-type food according to an embodiment of the present invention uses drone pupa extract, honey, black garlic essence, and dragon fruit powder as natural functional materials to prepare jelly with excellent taste, aroma, and texture, and exhibits an antioxidant effect enhancing effect. A functional natural jelly can be prepared.

In addition to the above-mentioned components, the jelly-like food composition of the present invention may further include one or more additional components selected from various nutritional components, functional components, and preference components according to the target health-promoting effect. These additional ingredients are preferably added to the mixture in the form of a premix prepared by mixing in advance.

The nutritional component may include at least one selected from vitamins, amino acids, mineral components, and proteins.

Minerals (electrolytes and trace elements) also common, for example, sodium chloride, sodium acetate, magnesium sulfate, magnesium chloride, calcium chloride, dipotassium phosphate, monosodium phosphate, calcium glycerophosphate, sodium ferric citrate succinate, sulfuric acid Manganese, copper sulfate, zinc sulfate, sodium iodide, potassium sorbate, zinc, manganese, copper, iodine, cobalt and the like can be exemplified. The blending amount of these can be appropriately determined as needed.

The preferred component may include food flavors such as fruit flavor, flower flavor, peppermint flavor, vanilla flavor, cream flavor, chocolate flavor, and caramel flavor, or natural products that are the source of the flavor in various forms such as concentrates or raw materials. It may further include various artificial or natural flavors and pigments for imparting or improving the color and flavor. The preferred ingredient includes a flavoring agent, and examples of the flavoring agent include coffee, matcha green tea, peanut paste, almond paste, spice, cacao mass, and cocoa powder.

In addition, in the production of the gel-like food of the present invention, suitable additives can be further added and blended as necessary to each predetermined amount of the above essential components. Here, as additives that can be added and blended as needed, coloring agents, flavoring agents, viscosity modifiers, acidulants, flavoring agents, acidity modifiers, food preservatives, stabilizers, grains, beans, vegetables, glycerin, propanol, sodium phosphite, sodium naphthalenesulfonate, Sodium laurine sulfonate etc. can be illustrated.

In addition, according to another aspect of the present invention, the present invention provides a premix comprising a drone pupal extract, honey, black garlic extract, and dragon fruit powder, and further mixing at least one selected from the group consisting of gums and flavoring agents to provide.

According to the present invention, a premix prepared by mixing the drone pupa extract, honey, black garlic essence, dragon fruit powder, gum, and flavoring agent in advance can be used.

In addition, according to another aspect of the present invention, the present invention provides a method for producing a functional natural gel-type food composition liquid comprising the following steps:

(a) preparing a liquid mixture by stirring the drone pupa extract, honey, black garlic extract, dragonfruit powder, gums and flavoring agents with purified water at a temperature of 60 to 100° C. for 1 minute to 4 hours; (b) cooling the mixture of step (a) at 1 to 20°C.

The method for producing functional natural jelly according to an embodiment of the present invention is a mixture obtained by simultaneously or time-dependently stirring purified water, drone pupal extract, honey, black garlic essence, dragon fruit powder, gum, and flavoring agent. It proceeds including the step of mixing. Each component used in the method is as described above.

The manufacturing method may further include one or more steps selected from the group consisting of filling the packaging material with the mixture and performing microbial sterilization.

A desired gel-like food product can be obtained by filling into an appropriate container and sterilizing it according to a conventional method. The sterilization may be performed by heat sterilization or aseptic filtration according to conventional methods. When a heat sterilization operation is employed as this sterilization operation, a heating operation prior to the sterilization operation is unnecessary because it also serves as a heating operation. When employing a sterilization operation not accompanied by heating, a heating operation is required prior to the sterilization operation. This heating operation can be carried out under the same conditions as the commonly employed heat sterilization operation.

The present invention provides a method for preparing a functional natural gel-type food composition solution in which the functionality of male bee pupa extract, honey, black garlic extract, and dragon fruit powder is enhanced, and a functional natural gel-type food composition solution prepared by the method. According to the present invention, compared to the conventional method, the functionality of the male bee extract, honey, black garlic extract, and dragon fruit powder can be fully utilized, and the preference of consumers for the functional natural gel-type food composition solution supplemented with diet function can be improved. It can be widely used in the development of functional health supplements using drone pupal extract, honey, black garlic essence and dragon fruit powder.

Composition liquid food preparation for ODF manufacturing Example

First, a functional natural jelly-type food is prepared by mixing and dissolving drone pupa extract, honey, black garlic extract, dragon fruit powder, appropriate amounts of gum, flavoring agents, and sugars in purified water. Briefly, it is as follows:

First, male bee pupae of 21 to 24 days old produced in beehives of western bee (Apis mellifera) breeding farms were collected, washed and dehydrated, and freeze-dried to a moisture content of 8 to 15% to prepare powder. The powdered drone pupa was reacted in an ultrasonicator for 3 hours by adding 10ℓ of 70% ethanol based on 1kg, removing the residues of the drone pupa with a filter paper, and adding tertiary distilled water to the filtered extract to 1/2-1/3 of the filtrate. After adding and shaking, the aqueous layer was separated and the removed extract was concentrated under reduced pressure at 40° C. using a rotary vacuum evaporator to obtain a drone pupa extract.

For honey, domestic acacia honey produced in May-June by Apis mellifera was purchased and used.

Black garlic is prepared by washing unpeeled whole garlic, freezing at -70 ° C within 24 hours, thawing at room temperature, aging at 90 ° C for 48 hours, aging at 80 ° C for 4 days, and aging at 60 ° C for 6 days. It was stored frozen at -70 ° C. After peeling off the outer skin of the aged garlic and crushing it, 10 times more water was added and heat extraction was performed at 95 ° C. for 6 hours to obtain black garlic extract.

Dragon fruit powder was obtained by removing the skin and seeds of the red dragon fruit, taking only the pulp, adding maltodextrin to the ground liquid solution, leaving it to stand for 2 hours, and freeze-drying to obtain a powder.

Mixed gums used a mixed gelling agent in which 0.6% by weight of agar, 0.4% by weight of carrageenan, 0.3% by weight of xanthan gum, and 0.1% by weight of locust bean gum were mixed.

Mixed gums, citric acid, vitamin C, flavoring agent (e.g., mixed fruit flavor), and oligosaccharide and fructose as sugars are added to the drone pupa extract, honey, black garlic extract, and dragon fruit powder prepared in advance as described above. Then, the mixture was mixed by stirring in purified water at a temperature of 85 ° C for 1 hour, poured into a mold and hardened in a 4 ° C refrigerator. By removing from the mold, a jelly-like food product was prepared.

At this time, in order to improve texture and functionality, the present inventors prepared a jelly-type food while changing the contents of the drone pupa extract, honey, black garlic essence, and dragon fruit powder according to the conditions of Preparation Examples 1 to 8 shown in Table 1 below. did

raw material name comparison
yes manufacturing
Example 1 manufacturing
Example 2 manufacturing
Example 3 manufacturing
example 4 manufacturing
Example 5 manufacturing
Example 6 manufacturing
yes 7 manufacturing
yes 8 note
Drone pupa extract (mg) 0 700 700 700 700 1,400 1,400 1,400 1,400 5.9 brix,
pH6.1 Acacia honey (ml) 400 400 400 400 400 400 400 400 400 liquid Black Garlic Juice (ml) 45 0 0 45 45 0 0 45 45 liquid dragon fruit powder (mg) 45 0 45 0 45 0 45 0 45 powder Mixed gum (mg) 85 85 85 85 85 85 85 85 85 powder Citric acid (mg) 20 20 20 20 20 20 20 20 20 powder Vitamin C (mg) 10 10 10 10 10 10 10 10 10 powder Flavoring agent (mg) 30 30 30 30 30 30 30 30 30 liquid Oligosaccharides (ml) 190 190 190 190 190 190 190 190 190 liquid Fructose (mg) 750 750 750 750 750 750 750 750 750 powder Purified water (ml) 2,350 2,350 2,350 2,350 2,350 2,350 2,350 2,350 2,350 liquid

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Experimental Example 1: sensory test

The present inventors performed a sensory test on the jelly-type foods of Preparation Examples 1 to 6 prepared above with 47 evaluators aged 20 to 60 years of age, male and female (1: very bad or none ↔ 5: very good or very good).

Table 2 shows the evaluation results for the taste, aroma and texture of the jelly-type food according to the mixing ratio of the ingredients.

As a result, it can be seen that the taste, aroma, texture and overall preference of the jelly-type foods according to Preparation Examples 5, 6 and 8 of the present invention are highly evaluated, and the sensory properties are excellent.

item comparative example Preparation Example 1 Preparation Example 2 Preparation Example 3 Production Example 4 Preparation Example 5 Preparation Example 6 Preparation Example 7 Preparation Example 8 taste 2 3 3 4 5 5 5 5 5 incense 2 2 5 3 3 4 5 4 4 texture One 2 3 2 2 5 4 4 5 preference 2 2 2 One One 4 5 4 4

Experimental Example 2: Evaluation of antioxidant efficacy

In addition, the antioxidant activity was evaluated by measuring the level of DPPH radical scavenging ability of the jelly-type foods of Preparation Examples 1 to 6 prepared above. Briefly:

DPPH (1,1-Diphenyl-2-picrylhydrazyl) radical scavenging ability was measured using the method of Cho et al. (2011). After mixing 0.1 ml of samples in which all extracts were dissolved in ethanol by concentration and 0.1 ml of 0.4 mM DPPH solution, they were reacted in the dark for 30 minutes.

The absorbance value was measured at 515 nm of a microplate reader (Molecular Devices, Sunnyvale, CA, USA), and the DPPH radical scavenging ability was calculated using the following formula. At this time, it was measured using vitamin C (Ascorbic acid) as a positive control.

DPPH radical scavenging activity (%) = [(Ac-As) / Ac] × 100

Ac: blank sample absorbance, As: sample group absorbance

division vitamin C comparative example Preparation Example 1 Preparation Example 2 Preparation Example 3 Production Example 4 Preparation Example 5 Preparation Example 6 Preparation Example 7 Preparation Example 8 EC50 value (mg/mL) 0.1 3.3 1.2 2.3 1.95 1.5 0.09 0.12 0.21 0.07

As a result, as shown in Table 3, it can be confirmed that Preparation Example 8 has remarkably excellent antioxidant activity for inhibiting DPPH.

Overall, looking at the above results, the jelly according to Preparation Example 8 among the jelly foods prepared using the drone pupal extract, honey, black garlic extract, and dragon fruit powder of the present invention as active ingredients had high taste, aroma, texture, and overall acceptability. It was evaluated and it can be seen that the sensory properties are excellent.

In addition, it was confirmed that it exhibits an excellent effect on antioxidant enhancement.

Therefore, the functional jelly of the present invention can be provided as a health food that also shows the effect of functionality while satisfying the taste of consumers.

First embodiment of ODF manufacturing method

The optimal embodiment of the ODF manufacturing method using the beekeeping product containing the drone pupa extract of the present invention from the ODF manufacturing composition according to the present invention will be described with reference to FIGS. 2 to 6.

Figure 2 shows the overall flow of the ODF manufacturing method using the beekeeping product including the drone pupa extract according to the present invention.

3 is a schematic diagram of a casting process in FIG. 2, FIG. 4 is a schematic diagram of an inspection process in FIG. 2, and FIG. 5 is a schematic diagram of a printing and slitting process in FIG. 2 , FIG. 6 is a schematic diagram of the packing process of FIG. 2 .

First, referring to FIG. 2, in the first step of the ODF manufacturing method using the beekeeping product containing the drone pupa extract according to the present invention, a functional natural gel-type food composition containing the drone pupa extract is mixed with a substrate for ODF production A composition solution for ODF production is prepared.

First, the composition for preparing ODF according to the present invention is described, a water-soluble polymer, which is an element that promotes dissolution and disintegration in the oral cavity, is selected, and in addition, a plasticizer for imparting flexibility to the ODF, and a dressing for increasing the compliance of medication Flavoring agents, coloring agents and sweetening agents are additionally required.

[Table 4] shows the component ratio of the specific composition for preparing ODF, including the functional natural gel-type food composition containing the drone pupa extract.

ingredient Weight ratio (% by weight) Functional natural gel-type food composition containing drone pupa extract 1 to 30 water soluble polymer 35 to 50 plasticizer 0 to 20 Surfactants handful sweetener 3 to 6 saliva stimulants 2 to 6 flavor and color handful

1) Water-soluble polymers should consider solubility with solvents used and whether or not precipitates occur, should not react with active ingredients and other additives, and should be of a type that is easy to handle without affecting the disintegration and dissolution time of the film. As it should be used, it is largely divided into 'natural polymer' and 'synthetic polymer', and the same types as in [Table 5] are considered.

category polymer natural polymer Pullulan, starch, gelatin, pectin, sodium alginate, maltodextrin, polymerized rosin synthetic polymer Hydroxypropyl methylcellulose. Sodium carboxymethylcellulose, polyethylene oxide. Hydroxypropyl cellulose, polyvinylpyrrolidone, polyvinyl alcohol. ethyl cellulose

2) Surfactant facilitates the dissolution or disintegration of ODF and acts as a dispersing agent that allows the active ingredient to be rapidly released within a few seconds.

Types of surfactants mainly used include sodium lauryl sulfate, benzalkonium chloride, and Tweens. In addition, there are also poloxamers.

3) Solubility of sweeteners with solvents should be considered. It is classified into 'natural sweeteners' and 'artificial sweeteners'. As natural sweeteners, sucrose, glucose, fructose, liquid glucose, and isomaltose are mainly used. In particular, fructose is widely used because it is sweeter than sorbitol and mannitol, and has good texture and refreshing feeling. For this purpose, polyhydric alcohols such as sorbitol, mannitol, and isomalt may be mixed and used.

Artificial sweeteners can be classified into 1st and 2nd generation. Among the 2nd generation artificial sweeteners, acesulfame potassium shows 200 to 600 times sweeter than sucralose, and neotame and illitam are 2000 to 2000 times sweeter than sucrose. It shows about 8000 times sweetness, and Leviana is a herbal sweetener derived from vegetable stevia and has about 200 to 300 times sweetness.

4) As a saliva-stimulating ingredient, ingredients used in food manufacturing such as citric acid, malic acid, lactic acid, ascorbic acid, and tartaric acid are ingredients that have the effect of stimulating the salivary glands, and are characterized by rapid disintegration and dissolution in the oral cavity, which is a characteristic of ODF formulations. plays a good role in promoting Of these, citric acid is most preferred.

5) In addition to the sweetener, other flavors may be added to mask the taste, for example strong mint flavor, fruit flavor, or sweet confectionery flavor.

6) Finally, for clear distinction, titanium dioxide, FD&C color, EU color, natural color, etc. can be added.

Now, the ODF composition solution according to the present invention is prepared, and as shown in FIGS. 2 and 3, it is cast into a film of appropriate thickness and then dried.

Thereafter, as shown in FIG. 4, vision inspection is performed, defective products are marked by punching, etc., and sealing is performed with an outer film.

Subsequently, as shown in FIG. 5, through a printing and slitting process, it is cut into an appropriate size, packaged as shown in FIG. 6, and shipped.

In particular, in the manufacturing method of the present invention, by making these overall processes a continuous process in one line, the flowability of the process can be shortened to about one day, productivity is improved by about 20%, and maintenance costs can be reduced It became.

(Second embodiment of ODF manufacturing method)

Now, with respect to the second embodiment of the ODF manufacturing method using the beekeeping product containing the drone pupa extract of the present invention from the ODF manufacturing composition according to the present invention, reference is mainly made to FIG. 7, and FIGS. 2 to 6 are supplementarily refer to and explain.

7 is a detailed flow chart of an ODF manufacturing method using a beekeeping product including a drone pupa extract according to the present invention.

First, referring to FIGS. 2 and 7, the first step of the ODF manufacturing method using the beekeeping product containing the drone pupa extract according to the present invention is the step of preparing the drone pupa extract (S10), in more detail, First, as an example, frozen drone pupae are thawed in water at 20 to 30 ° C. (S11), and after thawing, washing is performed using washing water, and a selection process of raw materials is performed to remove foreign substances using a sieve of a certain mesh ( S12).

Thereafter, the washed drone pupa is frozen at minus 30 to 45 ° C and then freeze-dried in a freeze dryer for 15 to 24 hours at a vacuum pressure of 300 torr to 500 torr (S13). After drying, for example, freeze-drying to a water content of 4% or less. However, depending on the condition of the raw material, it may be dried for several hours more.

Thereafter, the dried material is put into a grinder and pulverized to a size of 50 to 100 mesh (S14), and 70 to 90 parts by weight of 70% ethanol (preferably 75 to 85 parts by weight) is added to 100 parts by weight of the crushed drone pupa. , Most preferably 80 parts by weight) and extracted for 4 to 8 hours at a temperature of 40 to 60 ° C. (S15).

After extraction, the extract is concentrated under a vacuum pressure of 300 torr to 500 torr until the soluble solid content (brix) of the extract is 55 to 75 brix (preferably, 60 to 70 brix) (S16).

Now, a liquid composition for preparing an ODF is prepared using the beekeeping product containing the drone pupa extract obtained by the preparation of the drone pupa extract step (S10) in the steps S11 to S16.

Each essential component and composition ratio of the composition solution for preparing ODF is as shown in [Table 6] below.

raw material name Content (parts by weight) pullulan 10 to 14 modified starch 8 to 12 Drone pupa extract 8 to 12 propylene glycol 0.5 to 2 glycerin 0.5 to 2 honey 11 to 17 propolis 2 to 4 pollen extract 3 to 7 Purified water 33 to 55 Sum 100

That is, as a beekeeping product containing 10 to 14 parts by weight of pullulan and 8 to 12 parts by weight of modified starch, 0.5 to 2 parts by weight of propylene glycol and 0.5 to 2 parts by weight of glycerin, and a drone pupa extract, 8 to 12 parts by weight of a drone pupa extract and 11 to 17 parts by weight of honey, 2 to 4 parts by weight of propolis, 3 to 7 parts by weight of pollen extract, and 33 to 55 parts by weight of purified water.

Preferably, it is a beekeeping product comprising 11 to 13 parts by weight of pullulan and 9 to 11 parts by weight of modified starch, 0.8 to 1.5 parts by weight of propylene glycol and 0.8 to 1.5 parts by weight of glycerin, and a drone pupa extract. It consists of 13 to 15 parts by weight of honey, 2.5 to 3.5 parts by weight of propolis, 4 to 6 parts by weight of pollen extract, and 40 to 50 parts by weight of purified water.

Most preferably, 12 parts by weight of pullulan and 10 parts by weight of modified starch, 1 part by weight of propylene glycol and 1 part by weight of glycerin, 10 parts by weight of drone pupa extract, 14 parts by weight of honey, 3 parts by weight of propolis and 5 parts by weight of pollen extract and 44 parts by weight of purified water.

As described above, first, the essential components as shown in [Table 6] are mixed (S21), and optionally a plasticizer to impart flexibility to the ODF, and a flavoring agent, coloring agent, and sweetener to increase the compliance of the medication. Auxiliary materials may be added (S22).

Alternatively, in the case of the composition for preparing the ODF, it may be prepared by mixing the auxiliary materials together from the beginning in the same ratio as in [Table 4]. That is, 1 to 30 parts by weight of a functional natural gel-type food composition containing a drone pupa extract, 35 to 50 parts by weight of a water-soluble polymer, 0 to 20 parts by weight of a plasticizer, 3 to 6 parts by weight of a sweetener, 2 to 6 parts by weight of a salivary stimulant, and A liquid composition may be prepared by mixing a small amount of a surfactant, fragrance, and colorant. At this time, the water-soluble polymer should not react with the active ingredient and other additives, considering solubility with the solvent used and whether or not precipitate is generated, and is easy to handle without affecting the disintegration and dissolution time of the film. Should be used, it is largely divided into 'natural polymer' and 'synthetic polymer', and the same types as in [Table 5] are considered.

Additionally, in the case of the ODF preparation composition, 500 to 2000 parts by weight of drone pupal extract, 200 to 600 parts by weight of honey, 30 to 60 parts by weight of black garlic extract, 30 to 60 parts by weight of dragon fruit powder, 50 to 100 parts by weight of gum, 1 to 30 parts by weight of the flavoring agent and 1000 to 3000 parts by weight of purified water as seaborn components, and additional components may be further included therein.

Additionally, after preparing the composition liquid, preferably, air bubbles in the composition liquid are removed through a degassing process for about 30 to 40 minutes using a vacuum defoaming machine (S23).

Now, when the composition for ODF according to the present invention is prepared, as shown in FIGS. 2 and 3, put the composition for ODF into an ODF maker and make it into a film of appropriate thickness (for example, the thickness of the film is 0.02 to 1 mm). After casting (S31), hot air drying at a temperature of 60 ~ 70 ℃ (S32), after drying, the moisture content is dried to about 4 ~ 10%.

Thereafter, as shown in FIG. 4, vision inspection is performed (S33), defective products are marked by punching, etc. (S34), and sealing is performed with an outer film (S35).

Subsequently, as shown in FIG. 5, through a printing and slitting process (S36), cutting to an appropriate size (S37), and packaging with wrapping paper such as polyethylene or aluminum paper, for example, as shown in FIG. and shipped (S38). Additionally, sterilization is performed using a UV (100-280 nm wavelength) lamp so that the surface of the finished ODF film is not contaminated during packaging. In some cases, UVC sterilization may be used.

As described above, according to the manufacturing method of the present invention, by making these processes a continuous process in one line, the flowability of the process can be shortened to about one day, productivity is also improved by about 20%, and maintenance costs are improved. can also be reduced.

So far, the present invention has been described in detail with reference to the presented embodiments, but those skilled in the art can make various modifications and variations without departing from the technical spirit of the present invention with reference to the presented embodiments. will be. The present invention is not limited by these variations and modifications, but is limited only by the claims appended below.

Claims (6)

As an ODF manufacturing method using a beekeeping product containing a drone pupa extract,
(a) preparing a drone pupa extract (S10);
(b) preparing a liquid composition for preparing ODF using beekeeping products containing the drone pupa extract obtained in step (a) (S20); and
(c) manufacturing an ODF film by using the composition solution for preparing ODF prepared in step (b) (S30);
Including,
In step (a),
(a1) thawing the frozen drone pupae (S11);
(a2) a raw material sorting process step (S12) of washing the drone pupae thawed in step (a1) with washing water and removing foreign substances using a sieve of a certain mesh;
(a3) After (a2), the washed drone pupae are frozen at minus 30 to 45 ° C and then freeze-dried in a freeze dryer at a vacuum pressure of 300 torr to 500 torr for 15 to 24 hours, and then freeze-dried so that the moisture content is less than 4% Step (S13) of doing,
(a4) putting the dried material in step (a3) into a grinder and grinding it to a size of 50 to 100 mesh (S14);
(a5) mixing 75 to 85 parts by weight of 70% ethanol with 100 parts by weight of the drone pupa crushed in step (a4) and extracting at a temperature of 40 to 60 ° C. for 4 to 8 hours (S15);
(a6) after extraction in step (a5), concentrating until the soluble solid content (brix) of the extract is 60 to 70 brix under vacuum pressure of 300 torr to 500 torr (S16)
is made including,
In step (b),
(b1) 11-13 parts by weight of pullulan and 9-11 parts by weight of modified starch, 0.8-1.5 parts by weight of propylene glycol and 0.8-1.5 parts by weight of glycerin, a beekeeping product containing 9-11 parts by weight of drone pupa extract Preparation of 'functional natural gel-type food composition containing drone pupa extract' comprising 13 to 15 parts by weight of honey, 2.5 to 3.5 parts by weight of propolis, 4 to 6 parts by weight of pollen extract, and 40 to 50 parts by weight of purified water An essential ingredient mixing step (S21) to do;
(b2) 1 to 30% by weight of the 'functional natural gel-type food composition containing a drone pupa extract' prepared in step (b1), 35 to 50% by weight of water-soluble polymer, 0 to 20% by weight of plasticizer, 3 to 6% by weight of sweetener %, a salivary stimulant 2 to 6% by weight, and a supplementary material addition step (S22) of preparing a final ODF composition solution by mixing to include the rest of the surfactant, fragrance and colorant;
(b3) including the step (S23) of removing air bubbles in the composition liquid through a degassing process for 30 to 40 minutes using a vacuum defoaming machine after preparing the ODF composition liquid in step (b2);
In step (c),
(c1) putting the ODF-manufacturing composition solution into an ODF maker and casting it into a film having a certain thickness (S31);
(c2) after the step (c1), drying with hot air at a temperature of 60 to 70 ° C, drying so that the moisture content is 4 to 10% (S32);
(c3) after step (c2), performing vision inspection (S33) and marking defective products by punching (S34);
(c4) after the step (c3), a step (S35) of performing sealing with an outer film;
(c5) after the step (c4), through a printing and slitting process (S36), a step of cutting to an appropriate size (S37);
(c6) After the step (c5), a step (S38) of packaging while sterilizing using a UV lamp with a wavelength of 100 to 280 nm so that the surface of the finished ODF film is not contaminated,
ODF manufacturing method using a beekeeping product containing a drone pupa extract, characterized in that the overall processes of steps (c1) to (c5) are performed as a continuous process in one line. delete delete delete delete delete