KR102573065B1 - Body odor adsorption device and method - Google Patents

Abstract

An adsorption device for adsorption of body odor according to an embodiment of the present invention includes a stainless steel wire coated with an adsorbent; a fixing portion for accommodating and fixing the stainless steel wire; and an adsorption patch accommodating the stainless steel wire and the fixing portion; wherein the fixing part has a body odor passage passing through the fixing part in a predetermined direction, and both ends of the stainless steel wire, in a state where the adsorbent is positioned on the body odor passage, are connected to the fixing part. It may be characterized in that it is fixed and provided.

Description

Body odor adsorption device and method {Body odor adsorption device and method}

The present specification proposes a body odor absorption device and method used to absorb body odor as a preliminary work for body odor analysis.

In the case of SPME, which is a conventional method for adsorbing body odor, it is common to use a funnel to fix the SPME (Solid Phase Micro Extraction) device on the human skin when adsorbing body odor. However, these funnels were difficult to fix/adhere on human skin, and there was a problem in that the movement of the body odor adsorption site and the body odor adsorption time were limited. Furthermore, there is a problem that the accuracy of body odor analysis decreases as external body odor flows in due to a decrease in fixing force/adhesive force.

INME (In-Needle Micro Extraction) has been proposed and used to improve the problems of the SPME method, but in order for INME to be easily applied, it is essential to introduce an adsorbent capable of adsorbing both polar and non-polar substances.

In order to solve the above conventional problems, an object of the present specification is to propose a device for adsorbing body odor with improved fixation/adhesion to the user's skin and an adsorbent capable of adsorbing both polar and non-polar substances.

An adsorption device for adsorption of body odor according to an embodiment of the present invention includes a stainless steel wire coated with an adsorbent; a fixing portion for accommodating and fixing the stainless steel wire; and an adsorption patch accommodating the stainless steel wire and the fixing portion; wherein the fixing part has a body odor passage passing through the fixing part in a predetermined direction, and both ends of the stainless steel wire, in a state where the adsorbent is positioned on the body odor passage, are connected to the fixing part. It may be characterized in that it is fixed and provided.

According to one embodiment of the present invention, there is an effect that there is no restriction on movement of the body odor adsorption site and body odor adsorption time because the fixation/adhesion force to the user's skin is excellent.

In addition, according to an embodiment of the present invention, since an adsorbent capable of adsorbing both polar and non-polar substances is used, there is an effect that the accuracy and efficiency of body odor through the INME method can be maximized.

In addition, according to one embodiment of the present invention, since the manufacture of the adsorption device is easy and convenient, there is an effect that the cost of manufacturing the adsorption device can be minimized. In the same context, the recovery of the adsorbent from the adsorption device is also easy, so there is an effect that the cost of recovering the adsorbent can also be minimized.

In addition, various effects of the present invention will be described below as examples with reference to each drawing.

1 is a view illustrating the use of an adsorption device according to an embodiment of the present invention.
2 is a side enlarged view of an adsorption device according to an embodiment of the present invention.
3 is an enlarged plan view of an adsorption device according to an embodiment of the present invention.
4 is a diagram illustrating an adsorbent according to an embodiment of the present invention.
5 to 7 are flow charts illustrating a method for preparing and coating an adsorbent according to an embodiment of the present invention.
8 is a diagram illustrating a method of manufacturing a fixing part according to an embodiment of the present invention.
9 is a diagram illustrating a fixing unit according to another embodiment of the present invention.
10 is a diagram illustrating a coupling method between a fixing part and a stainless steel wire according to another embodiment of the present invention.
11 is a diagram illustrating an adsorption patch according to an embodiment of the present invention.
12 is a diagram illustrating a method of forming an adsorption patch according to an embodiment of the present invention.
13 is a diagram illustrating a method for taking out and analyzing an adsorbent according to an embodiment of the present invention.

Since the technology to be described below can have various changes and various embodiments, specific embodiments will be illustrated in the drawings and described in detail. However, this is not intended to limit the technology described below to specific embodiments, and it should be understood to include all modifications, equivalents, or substitutes included in the spirit and scope of the technology described below.

Terms such as first, second, A, B, etc. may be used to describe various elements, but the elements are not limited by the above terms, and are merely used to distinguish one element from another. used only as For example, without departing from the scope of the technology described below, a first element may be referred to as a second element, and similarly, the second element may be referred to as a first element. The terms and/or include any combination of a plurality of related recited items or any of a plurality of related recited items. For example, 'A and/or B' may be interpreted as meaning 'at least one of A or B'. Also, '/' can be interpreted as 'and' or 'or'.

In the terms used in this specification, singular expressions should be understood to include plural expressions unless clearly interpreted differently in context, and terms such as “comprising” refer to the described features, numbers, steps, operations, and components. , parts or combinations thereof, but it should be understood that it does not exclude the possibility of the presence or addition of one or more other features or numbers, step-action components, parts or combinations thereof.

Prior to a detailed description of the drawings, it is to be clarified that the classification of components in the present specification is merely a classification for each main function in charge of each component. That is, two or more components to be described below may be combined into one component, or one component may be divided into two or more for each more subdivided function. In addition, each component to be described below may additionally perform some or all of the functions of other components in addition to its main function, and some of the main functions of each component may be performed by other components. Of course, it may be dedicated and performed by .

In addition, in performing a method or method of operation, each process constituting the method may occur in a different order from the specified order unless a specific order is clearly described in context. That is, each process may occur in the same order as specified, may be performed substantially simultaneously, or may be performed in the reverse order.

1 is a view illustrating the use of an adsorption device according to an embodiment of the present invention, FIG. 2 is an enlarged side view of an adsorption device according to an embodiment of the present invention, and FIG. 3 is a view of an adsorption device according to an embodiment of the present invention. It is a flat magnification.

Referring to FIGS. 1 to 3 , the adsorption device 100 proposed herein may include a stainless steel wire 230 , a fixing part 220 and an adsorption patch 210 .

The adsorbent 240 may be coated on the stainless steel wire 230 by a predetermined length, and both ends are fixed to the fixing part 220, thereby fixing the adsorbent 240 in the fixing part 220. .

The adsorbent 240 may be made of a material capable of adsorbing both polar and non-polar so as to be suitable for the INME body odor collection method. The adsorbent 240 proposed in this specification is manufactured to include a graphene oxide; polyaniline/zinc oxide nanorod-/ZIF-8 (Zeolitic Imidazolate Framework-8) (GO; PANI/ZNRs/ZIF-8) composite layer. A detailed description of the adsorbent fabrication/coating method will be described below with reference to FIGS. 4 to 7.

The fixing part 220 may correspond to a configuration that performs a function of accommodating and fixing the stainless steel wire 230 . The fixing part 220 proposed in this specification may be made of PDMS material, and a specific manufacturing method will be described below with reference to FIG. 8 .

In order to accommodate and fix the stainless steel wire 230, the fixing part 220 may have a passage through which the body odor passes through the fixing part 220. In the present embodiment, the fixing part 220 is exemplified as a cylindrical shape through which a body odor passage passes through in a vertical direction, but is not limited thereto.

Both ends of the stainless steel wire 230 may be fixed to the fixing part 220 and accommodated inside the fixing part 220 in a state where the adsorbent 240 is positioned on the body odor passage of the fixing part 220 . The stainless steel wire 230 may be inserted into the inside in various ways depending on the structure of the fixing part 220 .

As an embodiment, when the fixing part 220 has a cylindrical structure illustrated in FIG. 2 as an inseparable integral structure, the stainless steel wire 230 is inserted into the body odor movement passage in a bent state, and then both ends are the fixing part By being fixed to 220, it can be accommodated in the fixing part 220. At this time, both ends of the stainless steel wire 230 may be fixed to the fixing part 220 in a state where the adsorbent 240 is located in the body odor passage. As such, since the adsorbent 240 is provided on the body odor passage, the adsorbent 240 may collect body odor moving along the body odor passage.

As another embodiment, when the fixing part 220 has a detachable structure, the stainless steel wire 230 can be accommodated in the fixing part 220 due to the coupling of the separated upper and lower parts, which is illustrated in FIG. 10 . It will be described later with reference to.

In order to efficiently collect body odor and prevent contamination of the adsorbent 240 , the width/radius of the body odor movement path of the fixing unit 220 may be determined based on the length/width of the coating of the adsorbent 240 . More specifically, the body odor passage width/radius may be set to a width where both ends of the fixing part 220 to which the stainless steel wire 230 is fixed are spaced apart from both ends of the adsorbent 240 at a predetermined interval. For example, when the coating length/width of the adsorbent 240 is 2 cm, the width/radius of the body odor passage may be determined to be 3 cm.

The adsorption patch 210 may perform a patch function to be adhered/attached/fixed to the human skin 110 by accommodating the stainless steel wire 230 and the fixing part 220 therein. The adsorption patch 210 may be made of a PDMS patch. The PDMS patch may correspond to a patch formed/made of an unscented PDMS polymer material that does not cause allergic components to the skin 110 . As shown in FIG. 2 , an adhesive pattern 250 for dry adhesion to the skin 110 may be formed on one surface of the adsorbent patch 210 according to a biomimetic dry adhesive system/principle. In the present specification, a case in which the adhesive pattern 250 has a cylindrical shape is exemplified, but is not limited thereto and may be formed in various shapes. A method of forming the adhesive pattern 250 will be described in detail below with reference to FIGS. 11 and 12 .

In the adsorption patch 210, the fixing part 220 in which the stainless steel wire 230 is accommodated and fixed is a body odor movement path on one side of the adsorption patch 210 (ie, the adhesive pattern 250 is formed thereon). side) to face the other side. As a result, the body odor absorbed from one side of the adsorbent patch 210 moves along the body odor passageway, can be discharged to the outside through the other side, and can be captured/collected by the adsorbent 240 placed on the body odor passageway. .

A heat treatment to improve the fixing force of the stainless steel wire 230 may be additionally performed on the adsorption patch 210 in which the stainless steel wire 230 and the fixing part 220 are accommodated. For example, as shown in FIG. 3 , heat treatment may be performed along a guide line passing through both ends of the stainless steel wire 230 . As a result, both ends of the stainless steel wire 230 are additionally fixed not only on the fixing part 220 but also on the adsorption patch 210, so that the fixing force of the stainless steel wire 230 within the adsorption patch 210 can be improved. there is.

The body odor collected/collected through the adsorption device 100 thus equipped can be collected by the INME method and used for body odor analysis. A detailed INME-based body odor analysis method will be described below with reference to FIG. 13 .

4 is a diagram illustrating an adsorbent according to an embodiment of the present invention, and FIGS. 5 to 7 are flow charts illustrating an adsorbent manufacturing and coating method according to an embodiment of the present invention.

As illustrated in FIG. 4, an adsorbent may be coated on a stainless steel wire with a predetermined length/width, and the adsorbent to be coated is graphene oxide; polyaniline/zinc oxide nanorods-/ZIF-8 (Zeolitic Imidazolate Framework- 8) (GO;PANI/ZNRs/ZIF-8) composite layers.

In more detail, referring to FIG. 5, the method for manufacturing an adsorbent according to an embodiment of the present invention includes forming a graphene oxide; polyaniline (GO) compound layer (S510); Graphene oxide; polyaniline/zinc oxide nanorods (GO; PANI/ZNRs (Zinc nanorods)) forming a composite layer (S520) and graphene oxide; polyaniline/zinc oxide nanorods-/ZIF-8 (Zeolitic Imidazolate Framework -8) forming a (GO;PANI/ZNRs/ZIF-8) composite layer (S530).

S510 may be a step of forming a graphene oxide; polyaniline (GO;PANI) compound layer through an electrochemical polymerization of an electrolyte solution containing graphene oxide and an aniline monomer.

FIG. 6 is a flowchart illustrating S510 of FIG. 5 in detail. Referring to FIG. 6, S510 is a step of preparing an electrolyte solution containing graphene oxide (GO) and an aniline monomer (S511) and a step of coating a graphene oxide; polyaniline (GO;PANI) compound layer on the working electrode (S511). S512) may be included.

S511 may be a step of preparing an electrolyte solution to form a GO;PANI compound layer. As an embodiment, the step of preparing an electrolyte solution is to add graphene oxide (GO) to a 0.5 M sulfuric acid solvent and perform sonication for about 3 hours to obtain graphene oxide (GO). Including the process of allowing the exfoliation to proceed and the process of adding aniline and further sonicating for about 1 hour to bond the graphene oxide (GO) with aniline. can do.

As an example, in the step of preparing the electrolyte solution, multiwall carbon nanotubes (MWCNTs) may be used as a substitute for graphene oxide (GO). Multi-walled carbon nanotubes (MWCNTs) have a large surface area, so they can be easily adsorbed and can contribute to increasing thermal stability. As another embodiment, in the step of preparing the electrolyte solution, as a substitute for graphene oxide (GO), graphene formed through reduction of graphene oxide (GO) may be used. When graphene is used, stability of the conductive polymer may be increased.

On the other hand, as an embodiment, polypyrrole can be used as a substitute for polyaniline (PANI) in graphene oxide; . Polypyrrole is a conductive polymer and has the advantage of enabling electropolymerization through an oxidation reaction of cyclic voltammetry (CV).

As another example, graphene oxide produced through a combination of graphene oxide (GO) and aniline; Poly(3,4-ethylenedioxythiophene) (PEDOT) as a substitute for polyaniline (PANI) in polyaniline (GO; PANI) ) can be used. PEDOT is a conductive polymer such as polyaniline and polypyrrole that is inexpensive and has high energy density. PEDOT can be formed through an electropolymerization reaction.

S512 may be a step of coating a graphene oxide; polyaniline (GO;PANI) compound layer on the working electrode through electrochemical polymerization of the aniline monomer included in the electrolyte solution prepared through S511.

As an example, cyclic voltammetry (CV) may be used to coat a stainless steel wire with a graphene oxide; polyaniline (GO; PANI) layer. For example, after immersing a stainless steel wire, a platinum counter electrode, and a silver-silver chloride reference electrode (Ag/AgCl reference electrode) in 8 mL of electrolyte solution, 25 to 50 mV/s at 0.6 to 1.0 V It may be a process that repeats at a rate of 25 to 35 cycles. Thereafter, an electropolymerization reaction of aniline is performed so that graphene oxide; polyaniline (GO; PANI) may be coated on the stainless steel wire.

On the other hand, a process of removing unreacted materials by flowing distilled water on the wire coated with graphene oxide; polyaniline (GO; PANI) and a process of drying in an oven at 80 ° C. for 30 minutes may be additionally performed.

Referring back to FIG. 5, S520 is graphene oxide generated through S510; graphene oxide by growing zinc oxide nanorods on a polyaniline (GO;PANI) compound layer; polyaniline/zinc oxide nano It may be a step of forming a rod (GO; PANI/ZNRs) composite layer.

FIG. 7 is a flowchart illustrating S520 of FIG. 5 in detail. Referring to FIG. 7 , S520 may include a first dipping step (S521), a step of drying the stainless steel wire (S522), a second dipping step (S523), and a step of heat treating the stainless steel wire (S524). .

S521 may be a first dipping step of dipping a stainless steel wire coated with graphene oxide; polyaniline (GO; PANI) in a mixture of zinc nitrate hexahydrate and hexamethylenetetramine. . As an example, the first dipping is dipping a wire coated with graphene oxide; polyaniline (GO; PANI) in 0.5 mL of a mixed solution of 0.3 to 0.7 M zinc nitrate hexahydrate and hexamethylenetetramine for 30 seconds. can be a process.

Here, when the concentration of the mixed solution of zinc nitrate hexahydrate and hexamethylenetetramine is less than 0.3 M, there is a problem in that isopropyl palmitate, one of the five target materials, is not adsorbed during dipping. On the contrary, when the concentration of the mixed solution exceeds 0.7 M, the amount of zinc nitrate hexahydrate and hexamethylenetetramine, which are added mixtures, is considerably increased, and there is a problem in that they are not dissolved in water. In consideration of this, in the first dipping, the concentration of the mixed solution of zinc nitrate hexahydrate and hexamethylenetetramine is preferably 0.3 to 0.7 M. Meanwhile, through the first dipping, a zinc oxide seed (ZnO seed) may be formed in the graphene oxide; polyaniline (GO; PANI) layer.

As an example, in the step of forming the graphene oxide; polyaniline/zinc oxide nanorods (GO; PANI/ZNRs) composite layer, zinc acetate is used as a substitute for zinc nitrate hexahydrate. can be used

Meanwhile, the first dipping step according to S521 may be repeatedly performed at least once.

Referring back to FIG. 7 , S522 may be a step of drying the stainless steel wire after the first dipping according to S521. As an example, S522 may be a process of drying for at least 1 minute in an oven at 110 to 273° C. after the first dipping.

Here, when the temperature for drying the stainless steel wire is less than 110° C., there is a problem in that the drying of the solution is not completely performed. Conversely, when the temperature at which the stainless steel wire is dried exceeds 273° C., there is a problem in that a mass change of graphene oxide; polyaniline (GO; PANI) occurs. Considering this, the drying temperature is preferably 110 to 273 °C.

Also, when the drying time is less than 1 minute, drying may not be sufficiently performed. In consideration of this, in the drying step, the drying time may be limited to 1 minute or more. Meanwhile, the drying step according to S522 may be repeatedly performed at least once.

Referring back to FIG. 7 , S523 may be a second dipping step of dipping the dried stainless steel wire according to S220 into a mixed solution of zinc nitrate hexahydrate and hexamethylenetetramine. As an example, the second dipping may be a process of dipping the stainless steel wire dried according to S522 into a mixed solution of 0.03 to 0.07 M zinc nitrate hexahydrate and hexamethylenetetramine.

Here, when the concentration of the mixed solution of zinc nitrate hexahydrate and hexamethylenetetramine is less than 0.03 M, there is a problem in that isopropyl palmitate, one of the five target materials, is not smoothly adsorbed during dipping. On the contrary, when the concentration of the mixed solution exceeds 0.07 M, there is a problem in that the zinc oxide nanorods (ZNRs) are irregular and grow to a considerable size and do not enter the needle. Considering this, the concentration of the mixed solution of zinc nitrate hexahydrate and hexamethylenetetramine is preferably 0.03 to 0.07 M.

S524 may be a step of heat-treating the stainless steel wire after the second dipping according to S523. As an example, the heat treatment may be performed in an oven at 60 to 100° C. for 1 to 4 hours.

Here, when the reaction temperature is less than 60° C., there is a problem in that the amount of adsorption of target materials is rapidly lowered. Conversely, when the reaction temperature exceeds 100 °C, there is a problem in that the amount of adsorption of the five target materials is significantly reduced. Considering this, the reaction temperature in the heat treatment is preferably 60 ~ 100 ℃.

In addition, when the reaction time is less than 1 hour, there is a problem in that the amount of adsorption of the five target materials is greatly reduced. When the reaction time is less than 1 hour, there is a problem in that zinc oxide (ZnO) present on the surface of graphene oxide; polyaniline (GO; PANI) does not sufficiently grow into zinc oxide nanorods (ZNRs). In this case, due to the lack of zinc oxide nanorods (ZNRs) used as a zinc source in the production reaction of zeolite imidazolate framework-8 (ZIF-8), 8) may not be sufficiently produced, and thus the adsorption amount may decrease. Conversely, when the reaction time exceeds 4 hours, adsorption of 2-nonenal, hexyl salicylate, and α-hexylcinnamaldehyde among the five target materials There is a problem that the amount is significantly reduced. Considering this, the reaction time is preferably 1 to 4 hours.

Through the above processes, zinc oxide seeds (ZnO seeds) formed on the graphene oxide; polyaniline (GO; PANI) layer can grow in the form of nanorods.

Referring back to FIG. 5, S530 reacts a 2-methylimidazole (2-MI) solution with graphene oxide; polyaniline/zinc oxide nanorods (GO; PANI/ZNRs) composite layer to graphene It may be a step of forming an oxide; polyaniline/zinc oxide nanorod-/ZIF-8 (GO; PANI/ZNRs/ZIF-8) composite layer.

Through the above-described manufacturing process, an adsorbent including a graphene oxide; polyaniline/zinc oxide nanorods/ZIF-8 (GO; PANI/ZNRs/ZIF-8) composite layer can be coated on the surface of the stainless steel wire.

Meanwhile, as an example, 1,4-Benzodicarboxylic acid may be used as a substitute for 2-methylimidazole (2-MI). In this case, MOF (Metal-Organic Framework)-5 can be generated using 1,4-benzodicarboxylic acid as a ligand, centering on zinc metal.

As another example, 4,4',4"-Benzene-1,3,5-triyl-tri-benzoic acid may be used as a substitute for 2-methylimidazole (2-MI). In this case, zinc MOF-177 can be produced using 4,4',4"-benzene-1,3,5-triyl-tri-benzoic acid as a metal-centered ligand.

As another example, 1,4-Benzodicarboxylic acid may be used as a substitute for 2-methylimidazole (2-MI). In this case, UiO-66 can be produced using 1,4-benzodicarboxylic acid as a ligand, centered on zinc metal.

As another example, Benzimidazole may be used as a substitute for 2-methylimidazole (2-MI). In this case, ZIF-7 can be produced using benzimidazole as a ligand, centering on zinc metal.

As another example, 2-Imidazolate carboxaldehyde can be used as a substitute for 2-methylimidazole (2-MI). In this case, ZIF-90 can be produced using 2-Imidazolate carboxaldehyde, a ligand centered on zinc metal.

As another example, 4,4'-(Hexafluoroiso-propylidene) bis (benzoic acid) may be used as a substitute for 2-methylimidazole (2-MI). In this case, Zn-FMOF can be produced using 4,4'-(hexafluoroiso-propylidene) bis (benzoic acid) as a ligand, centered on zinc metal.

8 is a diagram illustrating a method of manufacturing a fixing part according to an embodiment of the present invention.

As illustrated in FIG. 8 , a prefabricated fixing frame 810 using 3D printing technology may be provided to manufacture the fixing part 220 having a predetermined shape. Materials/materials generally used for 3D printing may be used as the material/material of the frame of the fixing unit. This drawing illustrates a fixing part frame 810 for fabricating a fixing part 220 having a cylindrical shape with a body odor movement passage having a radius of 3 cm in the center. The specific size of the fixing part frame 810 is as illustrated in the drawing, but is not limited thereto, and may be changed depending on the purpose of use, the region of use, and the like, of course. The fixing part 220 may be manufactured by pouring PDMS into the fixing part frame 810 and curing it, and then separating the cured PDMS from the fixing part frame.

In the case of the fixing part 220 manufactured according to the present embodiment, since it has a non-separable integral structure, after the stainless steel wire is bent and inserted into the body odor movement passage, both ends are fixed to both ends of the fixing part 220, thereby fixing the fixing part can be accommodated inside.

In addition, although not shown in this figure, after separating the cured PDMS from the fixing part frame 810, through holes are formed through both sides of the cured PDMS (for example, both sides of PDMS with a heat-treated needle). A fixing part (not shown) may be manufactured by using a penetrating method. At this time, the radius of the through hole may be formed to a length exceeding the width of the adsorbent. A stainless steel wire can be inserted into the fixing part through the side of the fixing part through the formed through-hole, and both ends of the stainless steel wire are fixed on the fixing part by heat-treating both ends in a state where the adsorbent is placed on the body odor movement passage. In this way, the stainless steel wire can be accommodated and fixed to the fixing part.

In this embodiment, the fixing part 220 may be manufactured in a cylindrical shape with a body odor movement passage formed in a vertical direction at the center, but is not limited thereto. Hereinafter, various shapes of the fixing part 220 are proposed.

9 is a diagram illustrating a fixing unit according to another embodiment of the present invention.

As illustrated in FIG. 9 , the fixing part 910 may be manufactured in an hourglass shape with a central portion depressed inward. In order to manufacture the fixing part 910 of the shape illustrated in this drawing, as suggested in FIG. 8 , a fixing part frame having an hourglass shape pre-manufactured by 3D printing technology may be engraved. Since the method of manufacturing the fixing part 910 using the fixing part frame is the same as described above with reference to FIG. 8 , overlapping descriptions will be omitted.

In this embodiment, both ends of the stainless steel wire 230 are fixed to the fixing part 910 in a state in which the adsorbent 240 is located in the narrowest passage (ie, the central part recessed inside) of the body odor movement passage. It can be accommodated in a fixed part. In order to efficiently collect body odor and prevent contamination of the adsorbent 240 , the width of the narrowest passage of the fixing part 910 may exceed the length/width of the coating of the adsorbent 240 .

According to the present embodiment, body odor can be collected from a wide skin area, and the body odor must be collected intensively by the adsorbent 240 due to the central recessed structure, so that the body odor collection rate/efficiency is very excellent. Therefore, the wearing time of the adsorption device for body odor collection is remarkably reduced, resulting in an effect of increasing usability and convenience.

10 is a diagram illustrating a coupling method between a fixing part and a stainless steel wire according to another embodiment of the present invention.

Referring to FIG. 10 , the fixing unit may be formed as a separable structure in which upper and lower parts 1010-1 and 1010-2 are separated. As suggested in FIGS. 8 and 9, the fixing part 1010 of this embodiment may be manufactured in a cylindrical or hourglass shape, but unlike the above-described integral structure, the upper and lower parts 1010-1 and 1010 It can be manufactured as a separable structure separated by -2). Even in this case, of course, the manufacturing method using the fixing frame illustrated in FIG. 8 may be applied, and separate fixing frame for manufacturing the upper fixing part and the lower fixing part may be provided.

When the fixing part 1010 is manufactured in a separable structure, the stainless steel wire 230 is inserted between the upper and lower parts 1010-1 and 1010-2 as illustrated in this figure, and the upper and lower parts 1010- 1, 1010-2 may be fixed on the fixing part 1010 as they are mutually coupled. In particular, both ends of the stainless steel wire 230 are fixed on the fixing part 1010 in a state where the adsorbent 240 is placed on the body odor passage formed in the upper and lower portions 1010-1 and 1010-2. It can be accommodated and fixed in the fixing part 1010 in a manner.

The upper and lower parts 1010-1 and 1010-2 of the fixing part 1010 are heat-cured and combined by heat-treating the entire boundary line in contact with each other, or a region where both ends of the stainless steel wire 230 are sandwiched (ie, stainless steel The region where the wire 230 protrudes) may be partially heat-cured and coupled to each other by heat treatment.

In the case of the latter, since the rest of the area except for the heat-hardened area is still separable into upper and lower parts, the fixing part 1010 can be separated into upper and lower parts 1010-1 and 1010-2 through the corresponding area to easily make stainless steel. The wire 230 can be taken out.

In the case of the former, since the upper and lower parts 1010-1 and 1010-2 are combined with each other through thermal curing, the stainless steel wire 230 can be taken out in the same way as the fixing part of the integral structure. More specifically, in the case of the former, the entire stainless steel wire 230 is bent and taken out through the body odor movement passage in a state in which the fixation is released, or one side of the fixing part is cut/opened by an external force to remove the stainless steel wire 230 can be extracted.

In this embodiment, a case in which the cylindrical fixing part 1010 is manufactured in an upper-lower (1010-1, 1010-2) separable structure is exemplified, but is not limited thereto, and the hourglass-shaped fixing part is also upper-lower (1010-1, 1010-2). Of course, the above description can be applied because it is manufactured as a lower separation type structure.

In addition, although not shown in this drawing, a spiral pattern is formed on the surface of the upper inner wall and the lower outer wall of the fixing part (except for the part where the stainless steel wire is fixed) so that the upper and lower parts of the fixing part are screwed together. It could be. At this time, the stainless steel wire may be spirally coupled with the lower or upper portion while being fixed to the upper or lower portion. In order to insert and fix the stainless steel wire in the upper or lower part, recessed parts may be formed on both sides of the part where the spiral pattern is formed, and screwed together with the lower part or upper part in a state where the stainless steel wire is inserted in the corresponding recessed part. It can be. According to this embodiment, since the upper and lower parts of the fixing unit can be coupled without a separate heat treatment process, the effect of fixing and collecting the adsorbent is very easy.

11 is a diagram illustrating an adsorption patch according to an embodiment of the present invention, and FIG. 12 is a diagram illustrating a method of forming an adsorption patch according to an embodiment of the present invention.

As described above, the adsorption patch 210 may be made of the PDMS patch, which is the same material as the fixing part. Therefore, the adsorption patch 210 can also be manufactured by pouring PDMS into the adsorption patch fabrication frame 1110 and then curing it, like the fixing part. 11 is a view illustrating such an adsorption patch manufacturing frame 1110, and may be manufactured in the size illustrated in this drawing, but is not limited thereto.

Referring to FIG. 11 , the suction patch fabrication frame 1110 may include a plurality of depressions 1120 engraved with a predetermined depth and shape to form an adhesive pattern on a silicon on insulator (SOI) substrate. In this drawing, a case in which the plurality of depressions 1120 are formed in a cylindrical shape is illustrated, but is not limited thereto. The plurality of depressions 1120 may be formed in a square shape and spaced apart at predetermined intervals in the SOI substrate.

Referring to FIG. 12 , an adsorption patch 210 may be manufactured by pouring PDMS into the adsorption patch fabrication frame 1110 of FIG. 11 and then curing the PDMS. At this time, on one surface of the adsorbent patch 210, the adhesive protrudes in a predetermined height and shape (cylindrical shape in the case of FIG. A pattern can be formed. Furthermore, as shown in FIGS. 12(b) and 12(c), in order to maximize the contact surface area with the skin to improve the skin contact force of the adsorption patch 210, the bottom surface of the adhesive pattern (in the case of this embodiment, a cylindrical shape) bottom surface) may be subjected to heat processing in a direction opposite to the direction of protrusion formation. For example, the adhesive pattern of the adsorption patch 210 may be placed on a hot plate for a predetermined time, and the surface area may be improved by melting the bottom surface of the adhesive pattern flat by the heat of the hot plate. As a result, as exemplified in this figure, the shape of the adhesive pattern may become an inverted mushroom shape.

By inserting the fixing part 240 to which the stainless steel wire 230 is fixed to the inside of the adsorption patch 210 manufactured as described above, manufacturing of the adsorption device can be completed.

Although not shown in this figure, pores may be formed on the other side of the adsorbent patch, and body odor may move rapidly from one side to the other side due to a difference in air pressure through the pores, enabling more efficient and rapid collection of body odor.

13 is a diagram illustrating a method for taking out and analyzing an adsorbent according to an embodiment of the present invention.

First, the stainless steel wire 230 may be taken out from the adsorption device that is adhered to the skin for a predetermined period of time and has completed collection of body odor (FIG. 13(a)). For extraction, the adsorption band and/or the fixture may be cut/disassembled. The stainless steel wire 230 taken out of the suction band and the fixing part may be injected into the needle 1310 (FIG. 13(b)), and the stainless steel wire 230 may be injected into the needle 1310. ) may be connected to the syringe 1320 (FIG. 13(c)). Thereafter, a needle 1310 is inserted into the GM/CS inlet 1330 to desorb the body odor components collected by the adsorbent 240 using a thermal desorption method. ) and can be collected and analyzed through a collection tube connected to (FIG. 13(d)).

Although it has been described herein that 3D printing materials generally available for 3D printing technology can be used for convenience of explanation, it is not limited thereto and can be replaced with materials that can perform the same/similar functions as common 3D printing materials. Of course there is.

For example, instead of 3D printing materials, polyethylene, polypropylene, polylactic acid and/or acrylonitrile butadiene stryrene may be used, and various molds may be manufactured using the materials to manufacture the structure of the adsorption device. In the case of polyethylene, it has strong durability and has the advantage of being lightweight as a material that is resistant to impact. In the case of polypropylene, it is characterized by being thermally stable and having a smooth surface. In the case of polylactic acid, it corresponds to the most widely used and universal 3D printer material. In the case of Acrylonitrile Butadiene Stryrene, it is composed of a stable and durable material and is used as the main material for 3D printers of the applied layering method.

In addition, PDMS can also be replaced with a material capable of performing the same/similar function, and for example, can be replaced with polypropylene, polyvinylsiloxane, polyurethane acrylate and/or poly methyl methacrylate. In the case of this alternative material, it is possible to form a nano-pillar structure and has an effect of excellent skin adhesion.

For convenience of description, each drawing has been divided and described, but it is also possible to design to implement a new embodiment by merging the embodiments described in each drawing. In addition, the present invention is not limited to the configuration and method of the described embodiments as described above, but the above-described embodiments are configured by selectively combining all or part of each embodiment so that various modifications can be made. It could be.

In addition, although preferred embodiments have been shown and described above, this specification is not limited to the specific embodiments described above, and those skilled in the art in the art to which the specification pertains without departing from the subject matter claimed in the claims Of course, various modifications are possible by the person, and these modifications should not be individually understood from the technical spirit or perspective of the present specification.

Claims (11)

In the adsorption device for body odor adsorption,
adsorbent-coated stainless steel wire;
a fixing portion for accommodating and fixing the stainless steel wire; and
an adsorption patch accommodating the stainless steel wire and the fixing part; Including,
The fixing part has a body odor passage passing through the fixing part in a predetermined direction,
The adsorption device, characterized in that both ends of the stainless steel wire are fixed to the fixing part in a state where the adsorbent is located on the body odor movement passage. According to claim 1,
The adsorption device, characterized in that an adhesive pattern for dry adhesion on the skin is formed on one surface of the adsorption patch. According to claim 2,
The adsorbent patch is characterized in that made of PDMS (Polydimethylsiloxane) material, the adsorption device. According to claim 3,
The adhesive pattern,
It is formed by protruding in the first direction and is composed of a plurality of cylindrical shapes spaced apart at predetermined intervals,
Characterized in that, the skin adhesive surface corresponding to the bottom surface of the cylindrical shape is formed by thermal processing in a second direction opposite to the first direction in order to increase the contact surface area with the skin. According to claim 2,
wherein the stainless steel wire and the fixing part are accommodated in the adsorption patch in a direction in which the body odor movement passage is directed from one surface of the adsorption patch to the other surface. According to claim 1,
The adsorbent includes a graphene oxide; polyaniline/zinc oxide nanorod-/ZIF-8 (Zeolitic Imidazolate Framework-8) (GO; PANI/ZNRs/ZIF-8) composite layer. According to claim 1,
The fixing part has a cylindrical shape or an hourglass shape in which a central portion is depressed inward. According to claim 7,
When the fixing part has the hourglass shape,
The adsorption device of claim 1 , wherein both ends of the stainless steel wire are fixed to the fixing part in a state in which the adsorbent is located in the narrowest passage of the body odor movement passage. According to claim 7,
When the fixing part is configured in the cylindrical shape, the predetermined direction is a vertical direction,
The width of the body odor movement passage is set to a width in which both ends of the fixing part are spaced apart from both ends of the adsorbent at a predetermined interval. According to claim 9,
The fixing part is divided into upper and lower parts,
The stainless steel wire is inserted between the upper part and the lower part so that the adsorbent is placed on the body odor movement passage, and then the upper part and the lower part are coupled to each other in a state where both ends are sandwiched between the upper part and the lower part, so that the fixing part Adsorption device, fixed on the bed. According to claim 10,
The upper and lower ends are coupled to each other by heat curing by partially heat-treating a region where both ends of the stainless steel wire are sandwiched.

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