KR102223332B1 - Hair-dye composition comprising liposome packed L-arginie and organic fatty acids - Google Patents

Abstract

The present invention relates to a hairdye composition comprising: a first solvent which causes swelling of a cuticle scale composed of keratin of the hair epidermis; and a second solvent including a component intended to be introduced between swollen cuticle layers. In particular, provided is a composition, wherein a first solvent additionally includes a component that can supplement a cell membrane complex auxiliary component lost in a cuticle layer swelling according to an action of the first solvent with a component that can perform a function similar to that thereof, or an L-arginine component may be additionally included to supplement the lost cell membrane complex auxiliary component, and the L-arginine component that may be additionally included is packaged in liposomes. Damage to hair can be minimized.

Description

Hair-dye composition comprising liposome packed L-arginie and organic fatty acids

The present invention relates to a hair-dye composition, wherein the composition comprises a first solvent that causes swelling of overlapped cuticle scales composed of keratin of the cuticle, and a second component comprising a component that is introduced between the swollen cuticle layer. Consist of a solvent, in particular, the first solvent additionally contains a component capable of performing a function similar to the cell membrane complex contained in the hair, or in addition to the first solvent L-arginine component, in particular, the L-arginine is a liposome It provides a composition having a characteristic that is packaged as.

Dyeing of human hair occurs frequently and popularly in daily life for cosmetic or other commercial purposes. Hair growth has a constant speed, but the speed is not fast enough, so in the case of damaged hair, the time required for a healthy hair to completely replace it is significant, which can occur as a result of other hair treatments such as dyeing or perm are performed. It is a situation that is difficult to replace as the growth of healthy hair.

Accordingly, in addition to achieving the basic purpose of changing the color of the hair, the hair dye used for dyeing the hair is also required to minimize damage to the hair that may accompany the process. Hair-dying agents are largely classified into permanent hair-dying agents, semi-permanent hair-dying agents, and temporary hair-dying agents based on the characteristics of the dye used therein and the period of fixation of the dye on the hair. Among them, permanent hair dyes, in particular, have a higher share than other types of hair dyes in the current related product market, and in particular, permanent hair dyes containing oxidizing dyes are widely used. Therefore, it can be said that in the case of a permanent hair dye containing an oxidizing dye, which is the most accessible based on current consumers, the need to achieve minimal hair damage compared to other types of hair dye is required.

As the permanent hair dye using the above oxidizing dye, a product including a first solvent including an oxidizing dye precursor, a coupler, and an alkalizing agent, and a second solvent including an oxidizing agent is widely used. The alkalizing agent contained in the first solvent has traditionally been used due to the volatility inherent in ammonia, but similarly, monoethanolamine or monoisopropanolamine is used due to the inherently odor and irritation to the mucous membrane.

The permanent hair dye using the above oxidizing dye is, in the case of a permanent hair dye, when the first solvent and the second solvent are mixed and applied to the hair, the alkalizing agent contained in the first solvent reacts with the oxidizing agent contained in the second solvent. Oxygen is generated, and the generated oxygen decomposes the melanin of the hair to bleach the hair, and at the same time, the oxidizing dye containing the oxidizing dye precursor contained in the first solvent is oxidized by the oxidizing agent of the second solvent, thereby oxidizing the above. In general, a dye precursor and a coupler undergo polymerization to form a dye bath, and the formed dye bath is deposited on the hair to perform a series of dyeing processes.

The hair is composed of the parietal quality, the cortex and the epidermis in the order adjacent to the center point of the longitudinal section of the hair. The composition in which the application of the solvent used for permanent hair dyeing occurs is the cortex and the epidermis, and the cortex is composed of cortical cells, which are crystalline areas, and intermittent substances, which are non-crystalline areas, and is natural by melamine granules present in the cortex. Since the color of the hair is expressed, the color of the hair is changed according to the action of the hair dye through the destruction of the previously existing melamine granules and the retention of the dye introduced by the hair dye.

In order for the dye to reach the cortex by the hair dye, the dye must pass through the cuticle layer of the epidermis present at the outermost part of the hair. The scale that makes up the cuticle layer that makes up the epidermis is an element composed of tightly coupled keratin proteins, protrudes in the same direction as the hair growth direction and has a structure that closely overlaps each other, and the cuticle layer is epidermis from the outer surface of the hair. It forms a layered structure in the order of cuticle, exo cuticle, and endo cuticle.

In the case of epicuticle, since the overlap between the angular scales is dense, chemical resistance is strong, but it is weak in physical force, and epicuticle has a relatively large amount of fatty acids in addition to protein components, so it is relatively hydrophobic. In the case of exocuticles, a relatively large number of cysteine amino acids are retained, and there are a number of cysteine bonds formed between the cysteine amino acids. In the case of endocuticle, it has relatively few cysteine bonds, has relatively hydrophilicity, corresponds to the inner side of the epidermis, and forms an adhesive connection through the outer side of the cortex and the auxiliary component of the cell membrane complex.

Most of the current permanent hair dyes are first solvents that have the purpose of achieving diffusion of dyes and other components secured through the opening by opening the overlapped cuticle layer of the epidermis with strong chemical resistance in order to introduce the dye into the cortex. And a second solvent containing the dye and other components desired to be introduced into the cortex. The first solvent is characterized in that it contains an alkalinizing agent. When the first solvent is applied to the hair, the alkalizing agent included in the first solvent passes between the scales constituting each cuticle layer of the cuticle, such as adhesion. It loses the cell membrane complex (CMC), which is connected in a way, and in particular loses the cell membrane complex auxiliary component between the scales constituting the epicuticle in advance. Afterwards, moisture and other components contained in the first solvent are introduced into the volume occupied by the lost cell membrane complex auxiliary component of the epicuticle, and the introduced components are continuously introduced between the cell membrane complexes that are lost by the action of an alkalizing agent. The cuticle and endocuticle are reached.

In particular, moisture among the components reached increases the volume of the endocuticle layer while being absorbed by the hydrophilic endocuticle layer, and as the volume of the relatively hydrophobic epicuticle layer is kept relatively constant, it is in a direction parallel to the hair. The degree of extension of the endocuticle layer is greater than that of the epicuticle and exocuticle layers per unit length of hair, and the connection between the cuticle layers is still maintained by the adhesive connection of the auxiliary components of the cell membrane complex that are not lost by the alkalizing agent. Due to this, each scale of the entire epidermis is curved toward the outside of the hair.

The opening of the cuticle, which is meant by the curvature, is maintained while the swelling of the endocuticle layer by moisture introduced from the outside is maintained, and when the second solvent is applied to the hair that continues to be maintained, the second solvent is contained. The ingredients can more easily pass through the epidermis and reach the cortex. When the desired chemical change made in the cortex by the hair dye is finished, the curvature must be completed to properly protect the cortex and airtightness of the epidermis, so that the composition introduced into the cortex or the changed composition in the cortex is maintained, The dyeing of the hair that the hair dye is intended to achieve is completed.

On the other hand, as can be found above, the loss of the auxiliary components of the cell membrane complex due to the alkalizing agent must be accompanied by essential for achieving the purpose of the permanent hair dye, but if the loss is excessive, the swelling of the cuticle layer of the cuticle of the cuticle ends and airtightness is achieved. In the process of formation, sufficient cell membrane complex auxiliary components may not be present to perform the adhesive connection between scales constituting the cuticle layer or between each cuticle layer at a desired level. In this case, as the curvature of the cuticle layer, particularly the epicuticle layer, is maintained, the airtightness of the cuticle is poor, and thus the physicochemical resistance of the cuticle is lowered.

Accordingly, the present invention provides a composition capable of minimizing damage to hair that is essential in the dyeing process by using a solvent containing L-arginine packaged in liposomes while L-arginine plays the role of an alkalinizing agent. There is a primary purpose.

In addition, the present invention can minimize damage to the hair that is essential in the dyeing process by including an organic fatty acid selected from the group consisting of conjugated linoleic acid or alpha linolenic acid in a dispersed state in the formulation of the product, and furthermore prevent damage to the hair that occurs. It is a second object to provide a recoverable composition.

In addition, the present invention is a third object to provide a composition capable of minimizing damage to the hair that is essential in the dyeing process by using a solvent containing keratin protein extracted from human hair and further repairing the damage that has occurred. There is this.

The present invention introduces L-arginine into the hair dye composition in order to solve the above problems of the permanent hair dye. However, since L-arginine has basic properties, if it is used directly, it may damage the skin of the user to which the hair dye may come into contact during the dyeing process, such as hair and scalp, so it is packaged with liposomes. When the liposome is introduced, it binds to the hydrophobic lipids constituting the remaining cell membrane complex auxiliary components, and at the same time, L-arginine is introduced into each structure of the hair to improve the quality of the hair. Furthermore, including L-arginine that is not packaged in liposomes in the alkalizing agent required for the first solvent, it plays a significant role in the swelling of hair through the alkalinity inherent in L-arginine.

Additionally, as a means to solve the above problems, the present invention introduces a keratin protein extracted from human hair into a hair dye composition in order to supplement the keratin protein in the exocuticle layer of the epidermis that may be damaged during the dyeing process. In particular, the introduced keratin protein is a short-chain keratin protein for ease of introduction.

Additionally, as a means to solve the above problems, the present invention provides conjugated linolieic acid and alpha linolienic acid to supplement the auxiliary components of the cell membrane complex of the epidermis that may be damaged during the staining process. An organic fatty acid selected from the group comprising: is introduced into the hair dye composition. Additionally, the selected organic fatty acid is included in the product in a dispersed state in order to overcome immiscibility with the hydrophilic component included in the hair dye.

As described below and as can be seen through the following experimental examples, the hair-dye composition according to the present invention contains L-arginine, which is a hair constituent, and in particular, liposomes so that the desired effect on the hair thereof is more excellently expressed. By further including the packaged L-arginine contained above, it acts as an alkalizing agent required for hair dyes inevitably accompanied by hair damage, and has an effect of restoring hair damaged by the above, and also in mokeratin and By containing an organic fatty acid selected from the group containing conjugated linoleic acid and alpha-linolenic acid, the cell membrane complex auxiliary components lost due to the action of an alkalizing agent in the process of swelling the cuticle of the cuticle of the cuticle are supplemented and supplemented to prevent damage to the hair caused by the application of a hair dye. It provides a useful effect of preventing and restoring.

Hereinafter, the present invention will be described in more detail.

The hair dye composition according to the present invention is composed of a first solvent including an oxidation dye precursor, a coupler, and an alkalizing agent, and a second solvent including an oxidizing agent. The first solvent contains L-arginine packaged in liposomes and L-arginine not packaged in liposomes.

The L-arginine packaged with the liposome can be obtained using liposome packaging technology that is obvious to those skilled in the art. The liposomes used may include deformable liposomes, elastic liposomes, ultra-flexible liposomes, and various other commercially available vesicles. When the size of the liposome containing L-arginine exceeds 750 nm, the transmittance to the cuticle rapidly decreases, so it is limited to the upper limit, and when it is less than 200 nm, it is difficult to contain sufficient L-arginine, so it is limited to the lower limit. When the L-arginine contained as the liposome is contained in excess of 3.0% by weight with respect to the total weight of the first solvent, there is no significant difference in the effect of hair quality improvement, so it is limited to the upper limit, and when it is contained in less than 0.05% by weight, it is used as the liposome. Since the effect of improving hair quality according to the included L-arginine is not significant, this is limited to the lower limit.

L-arginine that is not included as the liposome may use L-arginine, which is available through a route that is obvious to those skilled in the art. When the L-arginine not packaged with the liposome is contained in excess of 10.0% by weight based on the total weight of the first solvent, additional hair damage is observed as the pH of the first solvent increases more than necessary, so this is limited to the upper limit, If it is contained in an amount of less than 2.00% by weight, it does not sufficiently perform the role of an alkalinizing agent and thus does not sufficiently cause the loss of auxiliary components of the cell membrane complex of the hair epidermis, so that the hair is not sufficiently swelled, so this is limited to the lower limit.

The keratin protein extracted from the human hair is processed to be applicable to human hair by artificially extracting the keratin protein found throughout the hair, and it is apparent to those skilled in the art that when applied to human hair, it provides a moisturizing effect to the entire hair. . The keratin protein extracted from the human hair includes a short-chain keratin protein that can be obtained through a route that is obvious to those skilled in the art. Keratin extracted from the human hair is limited to the upper limit because there is no significant difference in the effect of improving hair quality when it is contained in excess of 1.0% by weight based on the total weight of the first solvent, and keratin extracted from human hair when it is contained in less than 0.1% by weight Since the protein is applied to human hair and the repair action of damaged hair is not achieved at the desired level, this is limited to the lower limit.

The conjugated linoleic acid and alpha linolenic acid are types of organic acids and function as fatty acids. The conjugated linoleic acid may be extracted from beef meat, rearing, chicken meat, milk, processed milk products, and safflower seeds, and the alpha linolenic acid may be extracted from flaxseed, walnut, chia, and hemp, and the extracted conjugated linoleic acid or alpha linolenic acid is a person skilled in the art. And conjugated linoleic acid or alpha linolenic acid, which are available via a route that is obvious to them. The organic fatty acid selected from the group containing the conjugated linoleic acid and alpha linolenic acid is a cell membrane complex that is present by temporarily or permanently replenishing the auxiliary component of the cell membrane complex of the epidermis lost by the alkalizing agent including arginine contained in the first solvent. It plays the role of restoring the adhesive connection between scales formed by auxiliary ingredients. By performing an adhesive linkage between scales with the residual cell membrane complex auxiliary component excluding the cell membrane complex auxiliary component of the lost hair epidermis among the cell membrane complex auxiliary components in which an organic fatty acid selected from the group including the conjugated linoleic acid and alpha linolenic acid is present, In the case of the hair to which the hair dye of the present invention is applied, damage to the hair is improved compared to the hair dye to which the organic fatty acid selected from the group containing the conjugated linoleic acid and alpha linolenic acid is not applied, thereby significantly improving the physicochemical properties of the hair after the completion of dyeing. The organic fatty acid selected from the group containing the conjugated linoleic acid and alpha linolenic acid may be introduced between the cuticles of the cuticle and mixed with the auxiliary component of the cell membrane complex. It can be introduced between the cuticles of the cuticle.

When the organic fatty acid selected from the group containing the conjugated linoleic acid and alpha linolenic acid is contained in an amount exceeding 3.0% by weight based on the total weight of the first solvent, there is no significant difference in the effect of improving hair quality and increases the immiscibility of the formulation. It is limited, and when it is contained in an amount of less than 0.5% by weight, there is no difference in effect on hair quality improvement from the case of applying the product to which the organic fatty acid selected from the group containing the conjugated linoleic acid and alpha linolenic acid is not applied, so it is limited to the lower limit.

As for the organic fatty acid selected from the group containing the conjugated linoleic acid and alpha linolenic acid, it is preferable that both the conjugated linoleic acid and the alpha linolenic acid are contained in the first solvent. In the case of the first solvent containing both the conjugated linoleic acid and the alpha linolenic acid, the total weight of the conjugated linoleic acid and the alpha linolenic acid contained is preferably 0.5 to 3.0% by weight based on the total weight of the first solvent.

Conjugated linoleic acid, alpha linolenic acid, or a combination thereof contained in the first solvent is preferably dispersed in the solvent since it is included in the first solvent. The means of dispersing thereof may be selected from dry or wet dispersing means obvious to those skilled in the art, such as a ball mill or a bead mill.

In the first solvent according to the present invention, in addition to the above components, an oxidizing dye and an alkalizing agent, which are typically included in a permanent dye containing an oxidizing dye, may be included within the range of the usual addition.

The oxidizing dye typically includes an oxidation dye precursor and a coupler, and the oxidation dye precursor is o-aminophenol, p-aminophenol, toluene hydrochloride,-2,5-diamine, p-phenylenediamine hydrochloride, toluene-2 ,5-diamine, p-phenylenediamine, sulfuric acid p-methylenediaminophenol, sulfuric acid o-aminophenol, sulfuric acid p-aminophenol, toluene sulfate-2,5-diamine and sulfuric acid p-phenylenediamine, etc. It may be selected from the group, and the coupler is 2-methyl-5-hydroxyethyl aminophenol, p-amino-o-cresol, m-aminophenol, 2,4-diaminophenoxyethanol hydrochloride, m-phenyl hydrochloride Rendiamine, m-phenylenediamine, N-methyl-p-phenylenediamine, p-amino-o-cresol sulfate, 4-ethoxy-m-phenylenediamine sulfate, m-phenylenediamine sulfate, alpha-naphthol , Resorcinol, 2-methylresorcinol, and the like.

The alkalizing agent may be selected from the group including ammonia, monoethanolamine, aminomethylpropanol, and the like that are commonly used.

In addition to the above oxidizing dyes and alkalizing agents, fatty alcohols selected from cetyl alcohol, oleyl alcohol, and non-henyl alcohol, which are commonly added to the first solvent, are added, or selected from polyoxyethylene cetyl ether or polyoxyethylene stearyl ether. Surfactants, carboxyvinyl polymers, hydroxyethyl cellulose, guar gum or xanthan gum, a thickener selected from the group including glycerol, 1,3-butylene glycol, and polyethylene glycol. It may be additionally included, and water may be further included to form a desired viscosity and formulation.

The second solvent to be mixed with the first solvent may include an oxidizing agent commonly used in a hair-dye composition that is commonly used, including hydrogen peroxide water as an oxidizing agent. For example, the oxidizing agent may include hydrogen peroxide solution, fatty acid alcohol, surfactant, and water, and if desired, may additionally include commonly used components.

The hair-dye composition comprising the first and second solvents is a formulation selected from the group consisting of formulations typically applied to hair-dye and cosmetic compositions, including lotions, creams, pastes, gels, aerosols and aerosol foams. It can be prepared in the form of, and when the first solvent and the second solvent are mixed and applied to the hair for a desired period of time and then removed with water or the like, dyeing of the hair is terminated.

Hereinafter, the present invention will be described in more detail through the following examples, but this is presented to aid in understanding the present invention, and it should be understood that it is not intended to limit the present invention to the following examples. It should be understood that the ranges such as addition of components that can be easily included, change of the manufacturing order, and change of the device to be used are clearly included in the following examples.

Examples 1 to 9 and Comparative Examples 1 to 9

In the preparation of the first solvent, glycerin, propylene glycol, ammonium thioglycolate, butyl thioglycolate, and L-arginine (L) were added to purified water heated to 50°C. -Arginine), Polyquaternium 10 and DL-Panthenol were added and heated to 80°C to dissolve all of them, and then p-aminophenol, m-aminophenol (( -Aminophenol), m-Phenylenediamine hydrochloride, p-Phenylenediamine, Polyquaternium 7 and L-Arginine packed with liposomes ) Was added, stirred and dissolved, cetyl alcohol, oleyl alcohol, liquid paraffin, and polyoxyethylene cetyl ether were mixed, and then heated to 80°C to dissolve. Conjugated Linoleic acid or Alpha-linolenic acid is added and dissolved by stirring, and then emulsified, and then Carbomer, Monoethanolamine, and Keratin are sequentially added. Then, the mixture was stirred and dissolved, and then cooled to 15° C. to prepare a creamy first solvent.

In the preparation of the second solvent, propylene glycol, phosphoric acid, sodium pyrophosphate, and polyquaternium 10 were added to purified water heated to 50° C. and then heated to 80° C. After dissolving all by heating, cetyl alcohol, polyoxyethylene cetyl ether, and phenacetin were mixed, heated to 80°C, and the dissolved solution was added to emulsify, and then cooled to 40°C. Hydrogen peroxide solution (Hydrogen Peroxide, 35%) was added to prepare a mucous second solvent.

Table 1

Table 2

Table 3

Table 4

Experimental example

The first and second solvents prepared in Examples 1 to 9 and Comparative Examples 1 to 9 were mixed at the same volume ratio, and then applied to human hair samples obtained from five different persons, and after a certain period of time, each of the same After washing with shampoo and drying for a certain period of time, 10 professional panelists who have worked in the beauty industry for more than 10 years are judged by the naked eye for moisture and dyeing, and for fastness and moisture to the touch, which is excellent (5 points) and good (4 points). ), normal (3 points), poor (2 points), very poor (1 point), and then the average of the scores is shown in Table 5 below.

Table 5

As can be seen in Table 5 above, the result of performing hair dyeing using the hair dyes of Examples 1 to 6 prepared according to the present invention is Comparative Example 1 prepared so that the composition ratio of the specific composition was out of the scope of the present invention. Compared to the results of hair dyeing using the hair dyes of to 6, it exhibits excellent effects in terms of moisture, dyeing, moisturizing and fastness.

In particular, in the case of including L-arginine packaged as liposomes through Examples 1 to 3 and Comparative Examples 1 to 3 according to the range disclosed in the present invention, a significant difference in fastness and staining property can be confirmed compared to those outside the above range. When the size of the liposome packaging L-arginine through Examples 4 to 6 and Comparative Examples 4 to 6 is within the range disclosed in the present invention, in terms of moisture, staining, moisturizing, and fastness compared to those outside the above range, Significant differences can be identified.

In addition, in the case of including inmokeratin according to the range disclosed in the present invention through Example 7 and Comparative Example 7, a significant difference in moisturizing effect can be confirmed, and the conjugated through Examples 8 and 9 and Comparative Examples 8 and 9 When an organic fatty acid selected from the group including linoleic acid and alpha-linolenic acid is included according to the range disclosed in the present invention, a significant difference can be confirmed in terms of moisture, dyeing property, moisturizing property and fastness.

Claims (4)

In the hair-dye composition comprising a first solvent containing an oxidizing dye and an alkalizing agent and a second solvent containing an oxidizing agent,
L-arginine packaged in liposomes is contained in an amount of 0.05 to 3.0% by weight based on the total weight of the first solvent;
The combination of conjugated linoleic acid and alpha linolenic acid is contained in an amount of 1.0 to 2.5% by weight based on the total weight of the first solvent; And
The liposome packaging the L-arginine packaged with the liposome is characterized in that it is bound to the auxiliary component of the cell membrane complex of the epicuticle layer constituting the epidermis,
Hair-dye composition. The hair dye composition of claim 1, wherein the liposome packaging L-arginine packaged with the liposome has a diameter of 200 to 750 nm. The hair-dye composition according to claim 2, wherein inmokeratin is contained in an amount of 0.1 to 1.0% by weight based on the total weight of the first solvent. delete