JPWO2023048158A5 - - Google Patents
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- JPWO2023048158A5 JPWO2023048158A5 JP2023549710A JP2023549710A JPWO2023048158A5 JP WO2023048158 A5 JPWO2023048158 A5 JP WO2023048158A5 JP 2023549710 A JP2023549710 A JP 2023549710A JP 2023549710 A JP2023549710 A JP 2023549710A JP WO2023048158 A5 JPWO2023048158 A5 JP WO2023048158A5
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- frequency spectrum
- apnea syndrome
- sleep apnea
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- 201000002859 sleep apnea Diseases 0.000 claims description 26
- 238000001228 spectrum Methods 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 14
- 238000003745 diagnosis Methods 0.000 claims description 7
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 5
- 230000008667 sleep stage Effects 0.000 claims 8
Description
【０００３】
しかしながら、健常者であっても、状況によっては深い睡眠ができない場合も多々あり、睡眠中の睡眠段階が覚醒になる回数が多いからと言って、それだけで無呼吸症候群と判断することはできない。このため、無呼吸症候群をより的確な判定することが急務となっていた。
［０００９］
以上説明したように、被測定者への負担をかけずに睡眠時無呼吸症候群の判定を行うことが可能な無呼吸症候群判定装置、無呼吸症候群判定方法およびプログラムの開発が望まれていた。
課題を解決するための手段
［００１０］
本発明の睡眠時無呼吸症候群判定装置は、被測定者の睡眠中の心拍、呼吸、及び体動による生体振動データを取得する生体データ取得部と、生体データ取得部が取得した生体振動データを周波数解析して、覚醒以外と判定された箇所の周波数スペクトルの平均を取得する生体データ処理部と、生体データ処理部で得られた周波数スペクトルの平均の対数値に対する近似曲線を取得すると共に、生体データ取得部で得られた周波数スペクトルの平均の対数値が、取得した近似曲線から正の方向または負の方向に外れる量を検出し、検出した近似曲線から正の方向または負の方向に外れた量の大きさに基づいて、被測定者が睡眠時無呼吸症候群であるかの判定を行う判定部と、を備える。
［００１１］
また、本発明の睡眠時無呼吸症候群判定方法は、被測定者の睡眠中の心拍、呼吸、及び体動による生体振動データを取得する生体データ取得処理と、生体データ取得処理により取得した生体振動データを周波数解析して、覚醒以外と判定された箇所の周波数スペクトルの平均を取得する生体データ処理と、生体データ処理によ[0003]
However, even healthy people often have difficulty in deep sleep depending on the circumstances, and the fact that a person has a high number of awakenings during sleep alone is not enough to determine whether they have sleep apnea syndrome. For this reason, there has been an urgent need to develop a method for more accurate diagnosis of sleep apnea syndrome.
[0009]
As described above, there has been a demand for the development of an apnea syndrome assessment device, an apnea syndrome assessment method, and a program that are capable of assessing sleep apnea syndrome without imposing a burden on the person being measured.
Means for solving the problem [0010]
The sleep apnea syndrome diagnosis device of the present invention comprises a bio-data acquisition unit that acquires bio-vibration data from the heart rate, breathing, and body movements of the subject while sleeping, a bio-data processing unit that performs frequency analysis of the bio-vibration data acquired by the bio-data acquisition unit to acquire the average of the frequency spectra of areas determined to be other than awake, and a diagnosis unit that acquires an approximation curve for the logarithmic value of the average of the frequency spectra obtained by the bio-data processing unit and detects the amount by which the logarithmic value of the average of the frequency spectra obtained by the bio-data acquisition unit deviates in the positive or negative direction from the acquired approximation curve, and determines whether the subject has sleep apnea syndrome based on the magnitude of the deviation in the positive or negative direction from the detected approximation curve.
[0011]
The sleep apnea syndrome diagnosis method of the present invention includes a bio-data acquisition process for acquiring bio-vibration data due to the heart rate, breathing, and body movement of the subject while sleeping, a bio-data acquisition process for frequency-analyzing the bio-vibration data acquired by the bio-data acquisition process, and acquiring an average of the frequency spectrum of the part determined to be other than awake, and a bio-data acquisition process for acquiring the average of the frequency spectrum of the part determined to be other than awake.
Claims (13)
前記生体データ取得部が取得した前記生体振動データを周波数解析して、覚醒以外と判定された箇所の周波数スペクトルの平均を取得する生体データ処理部と、
前記生体データ処理部で得られた周波数スペクトルの平均の対数値の単峰性に基づいて、前記被測定者が睡眠時無呼吸症候群であるかの判定を行う睡眠時無呼吸症候群判定部と、を備える
睡眠時無呼吸症候群判定装置。 A biological data acquisition unit that acquires biological vibration data due to the heart rate, breathing, and body movement of the subject while sleeping;
A biological data processing unit that performs frequency analysis on the biological vibration data acquired by the biological data acquisition unit and acquires an average of the frequency spectrum of a portion determined to be other than awake;
and a sleep apnea syndrome determination unit that determines whether the subject has sleep apnea syndrome based on the unimodality of the logarithm of the average of the frequency spectrum obtained by the biological data processing unit.
請求項１に記載の睡眠時無呼吸症候群判定装置。 2. The sleep apnea syndrome diagnosis device according to claim 1, wherein the sleep apnea syndrome diagnosis unit calculates an approximation curve for the logarithmic value of the average of the frequency spectrum, and determines whether the logarithmic value of the average of the frequency spectrum is unimodal by comparing the logarithmic value of the average of the frequency spectrum with the approximation curve.
前記生体データ処理部は、前記入力部より入力された前記近似曲線の情報に基づいて前記近似曲線を算出する
請求項２に記載の睡眠時無呼吸症候群判定装置。 An input unit for inputting information on the approximation curve is further provided,
The sleep apnea syndrome assessment device according to claim 2 , wherein the biological data processing unit calculates the approximation curve based on information of the approximation curve inputted from the input unit.
請求項２に記載の睡眠時無呼吸症候群判定装置。 The sleep apnea syndrome assessment device according to claim 2 , wherein the approximation curve is calculated by excluding the lowest frequency component contained in the biological vibration data.
前記睡眠時無呼吸症候群判定部は、前記睡眠段階判定部が判定した睡眠段階が、覚醒以外の睡眠段階の区間、覚醒の睡眠段階の区間、並びに覚醒以外及び覚醒の双方の睡眠段階の区間のいずれかについて、周波数ごとの平均の対数値を取得して判定する
請求項１または２に記載の睡眠時無呼吸症候群判定装置。 Further, a sleep stage determination unit is provided for determining a sleep stage of the subject at regular intervals based on a result of frequency analysis of the biological vibration data.
3. The sleep apnea syndrome assessment device according to claim 1, wherein the sleep stage assessment unit assesses the sleep stage by acquiring an average logarithm of each frequency for a section of a sleep stage other than awake, a section of a awake sleep stage, or a section of both a sleep stage other than awake and a awake sleep stage.
請求項１に記載の睡眠時無呼吸症候群判定装置。 2. The sleep apnea syndrome assessment device of claim 1, wherein the sleep apnea syndrome assessment unit calculates an approximation curve for an average logarithm of the frequency spectrum obtained by the biological data acquisition unit, detects an amount by which the average logarithm of the frequency spectrum obtained by the biological data acquisition unit deviates in a positive or negative direction from the calculated approximation curve, and determines whether the subject has sleep apnea syndrome based on the magnitude of the deviation in the positive or negative direction from the detected approximation curve.
請求項６に記載の睡眠時無呼吸症候群判定装置。 7. The sleep apnea syndrome assessment device according to claim 6, wherein the sleep apnea syndrome assessment unit determines whether the subject has sleep apnea syndrome based on the amount by which the average logarithm around 3 Hz deviates from the approximation curve in a positive direction.
前記生体データ取得処理により取得した前記生体振動データを周波数解析して、覚醒以外と判定された箇所の周波数スペクトルの平均を取得する生体データ処理と、
前記生体データ処理により得られた周波数スペクトルの平均の対数値に対する近似曲線を取得する近似曲線取得処理と、
前記生体データ処理により得られた周波数スペクトルの平均の対数値の単峰性に基づいて、前記被測定者が睡眠時無呼吸症候群であるかの判定を行う判定処理と、を含む
睡眠時無呼吸症候群判定方法。 A biological data acquisition process for acquiring biological vibration data due to the heart rate, breathing, and body movement of the subject while sleeping;
A biological data process for performing frequency analysis on the biological vibration data acquired by the biological data acquisition process to acquire an average of the frequency spectrum of the portion determined to be other than awake;
an approximation curve acquisition process for acquiring an approximation curve for the logarithm of the average of the frequency spectrum obtained by the biological data processing;
and a determination process for determining whether the subject has sleep apnea syndrome based on the unimodality of the logarithmic average of the frequency spectrum obtained by the biological data processing.
前記生体データ取得手順により取得した前記生体振動データを周波数解析して、覚醒以外と判定された箇所の周波数スペクトルの平均を取得する生体データ処理手順と、
前記生体データ処理手順により得られた周波数スペクトルの平均の対数値に対する近似曲線を取得する近似曲線取得手順と、
前記生体データ処理手順により得られた周波数スペクトルの平均の対数値の単峰性に基づいて、前記被測定者が睡眠時無呼吸症候群であるかの判定を行う判定手順と、
をコンピュータに実行させるプログラム。 A bio-data acquisition procedure for acquiring bio-vibration data due to the heart rate, breathing, and body movement of the subject while sleeping;
a biological data processing step of performing frequency analysis on the biological vibration data acquired by the biological data acquisition step to acquire an average of the frequency spectrum of the portion determined to be other than awake;
an approximation curve acquisition step of acquiring an approximation curve for the average logarithm of the frequency spectrum obtained by the biometric data processing step;
a determination step of determining whether the subject has sleep apnea syndrome based on the unimodality of the logarithm of the average of the frequency spectrum obtained by the biological data processing step;
A program that causes a computer to execute the following.
請求項１に記載の睡眠時無呼吸症候群判定装置。 The sleep apnea syndrome determination device according to claim 1 , wherein the biological data processing unit further acquires an average of the frequency spectrum of the area determined to be awake or an average of the frequency spectrum of both the area determined to be awake and the area determined to be other than the area.
請求項１に記載の睡眠時無呼吸症候群判定装置。 The sleep apnea syndrome assessment device according to claim 1 , wherein the biological data acquisition unit detects biological vibration data from a pressure sensor installed on or in a mattress.
請求項８に記載の睡眠時無呼吸症候群判定方法。 The sleep apnea syndrome diagnosis method according to claim 8 , wherein the biological data processing further includes obtaining an average of the frequency spectrum of the area determined to be awake or an average of the frequency spectrum of both the area determined to be awake and the area determined to be other than the area.
請求項９に記載のプログラム。 The program according to claim 9 , wherein the biological data processing step further includes obtaining an average of the frequency spectrum of the area determined to be awake or an average of the frequency spectrum of both the area determined to be awake and the area determined to be other than awake.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021154796 | 2021-09-22 | ||
| PCT/JP2022/035080 WO2023048158A1 (en) | 2021-09-22 | 2022-09-21 | Sleep apnea syndrome determination device, sleep apnea syndrome determination method, and program |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023048158A1 JPWO2023048158A1 (en) | 2023-03-30 |
| JPWO2023048158A5 true JPWO2023048158A5 (en) | 2024-07-12 |
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| JP2023549710A Pending JPWO2023048158A1 (en) | 2021-09-22 | 2022-09-21 |
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| JP (1) | JPWO2023048158A1 (en) |
| WO (1) | WO2023048158A1 (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6168568B1 (en) * | 1996-10-04 | 2001-01-02 | Karmel Medical Acoustic Technologies Ltd. | Phonopneumograph system |
| JP2010162341A (en) * | 2008-12-15 | 2010-07-29 | Kagoshima Univ | Automatic sleep stage determination system and automatic sleep stage determination method |
| EP2457504B1 (en) * | 2009-07-24 | 2014-07-16 | Fujitsu Limited | Sleep apnea syndrome examination device and program |
| US20130190642A1 (en) * | 2010-10-01 | 2013-07-25 | Koninklijke Philips Electronics N.V. | Apparatus and method for diagnosing obstructive sleep apnea |
| JP6721153B2 (en) * | 2016-04-15 | 2020-07-08 | オムロン株式会社 | Biological information analysis device, system, and program |
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