JPS6483092A - Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component - Google Patents

Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component

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Publication number
JPS6483092A
JPS6483092A JP23925587A JP23925587A JPS6483092A JP S6483092 A JPS6483092 A JP S6483092A JP 23925587 A JP23925587 A JP 23925587A JP 23925587 A JP23925587 A JP 23925587A JP S6483092 A JPS6483092 A JP S6483092A
Authority
JP
Japan
Prior art keywords
derivative
carcinostatic
dimethyladenosine
novel
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP23925587A
Other languages
Japanese (ja)
Inventor
Shintaro Arakawa
Shuichi Ogawa
Eitaro Arakawa
Tetsuo Kato
Tsukasa Takamura
Taketoshi Kato
Kyoko Suzumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arakawa Chotaro & Co
ARAKAWACHIYOUTAROU KK
Original Assignee
Arakawa Chotaro & Co
ARAKAWACHIYOUTAROU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arakawa Chotaro & Co, ARAKAWACHIYOUTAROU KK filed Critical Arakawa Chotaro & Co
Priority to JP23925587A priority Critical patent/JPS6483092A/en
Publication of JPS6483092A publication Critical patent/JPS6483092A/en
Pending legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The N<6>,N<6>-dimethyladenosine sugar ester derivative of formula I (R is >=4C alkyl >=2C halogenated alkyl, >=4C alkyl having 1,2-dithiolane ring at the terminal, >=4C alkenyl or alkynyl) or its isopropylidene derivative at 2,3-sites of the sugar part. USE:A carcinostatic agent. PREPARATION:2',3'-0-isopropylidene-N<6>,N<6>-dimethyladenosine of formula II is made to react with carboxylic acids or carboxylic acid halides of formula III (X is OH or halogen) and, as necessary, removing the isopropylidene group by acid hydrolysis.
JP23925587A 1987-09-24 1987-09-24 Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component Pending JPS6483092A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP23925587A JPS6483092A (en) 1987-09-24 1987-09-24 Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23925587A JPS6483092A (en) 1987-09-24 1987-09-24 Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component

Publications (1)

Publication Number Publication Date
JPS6483092A true JPS6483092A (en) 1989-03-28

Family

ID=17042041

Family Applications (1)

Application Number Title Priority Date Filing Date
JP23925587A Pending JPS6483092A (en) 1987-09-24 1987-09-24 Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component

Country Status (1)

Country Link
JP (1) JPS6483092A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06511249A (en) * 1991-10-07 1994-12-15 ノルスク・ヒドロ・アーエスアー Compound
US5958309A (en) * 1996-03-06 1999-09-28 Idemitsu Petrochemical Co., Ltd. Method for manufacturing thermoplastic sheets bearing embossed patterns thereon and an apparatus therefor
US6153594A (en) * 1993-04-05 2000-11-28 Norsk Hydro As 5'-O-acylated antiviral nucleosides
USRE38495E1 (en) * 1996-03-06 2004-04-13 Idemitsu Petrochemical Co., Ltd. Method for manufacturing thermoplastic sheets bearing embossed patterns thereon and an apparatus therefor
EP2711008A1 (en) 2012-09-19 2014-03-26 Institut Univ. de Ciència i Tecnologia, S.A. N6,N6-dimethyladenosine for use in treating or preventing primary and metastatic breast cancer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06511249A (en) * 1991-10-07 1994-12-15 ノルスク・ヒドロ・アーエスアー Compound
US6548486B1 (en) 1991-10-07 2003-04-15 Norsk Hydro A.S. Fatty acid esters of nucleoside analogs
US6153594A (en) * 1993-04-05 2000-11-28 Norsk Hydro As 5'-O-acylated antiviral nucleosides
US5958309A (en) * 1996-03-06 1999-09-28 Idemitsu Petrochemical Co., Ltd. Method for manufacturing thermoplastic sheets bearing embossed patterns thereon and an apparatus therefor
USRE38495E1 (en) * 1996-03-06 2004-04-13 Idemitsu Petrochemical Co., Ltd. Method for manufacturing thermoplastic sheets bearing embossed patterns thereon and an apparatus therefor
EP2711008A1 (en) 2012-09-19 2014-03-26 Institut Univ. de Ciència i Tecnologia, S.A. N6,N6-dimethyladenosine for use in treating or preventing primary and metastatic breast cancer

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