JPS575699A - Production of glutathione - Google Patents

Production of glutathione

Info

Publication number
JPS575699A
JPS575699A JP7996280A JP7996280A JPS575699A JP S575699 A JPS575699 A JP S575699A JP 7996280 A JP7996280 A JP 7996280A JP 7996280 A JP7996280 A JP 7996280A JP S575699 A JPS575699 A JP S575699A
Authority
JP
Japan
Prior art keywords
synthetase
glutathione
cystein
glutamyl
act
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7996280A
Other languages
Japanese (ja)
Other versions
JPS6251600B2 (en
Inventor
Hidehiko Kumagai
Tatsurokuro Tochikura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP7996280A priority Critical patent/JPS575699A/en
Publication of JPS575699A publication Critical patent/JPS575699A/en
Publication of JPS6251600B2 publication Critical patent/JPS6251600B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: After brought into contact with a SH-group modifying reagent, γ-glutamyl-cystein synthetase is made to act on L-glutamic acid, L-cystein and glycine together with glutathione synthetase or produce the titled substance in high yield.
CONSTITUTION: γ-Glutamyl-cysteine synthetase is suspended in a buffer solution and brought into contact with a SH group-modifying reagent such as p-chlromercuribenzoic acid, or iodoacetic acid amide by adding the reagent to the suspension. The resultant γ-glutamy-cysteine synthetase and glutathione synthetase are made to act on L-glutamic acid, L-cystein and glycine together in an aqueous solution. An antioxidant, a surfactant and other additives may be added to the reaction mixture. The isolation and purification of glutathione from the reaction mixture is effected by a usual method.
COPYRIGHT: (C)1982,JPO&Japio
JP7996280A 1980-06-13 1980-06-13 Production of glutathione Granted JPS575699A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7996280A JPS575699A (en) 1980-06-13 1980-06-13 Production of glutathione

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7996280A JPS575699A (en) 1980-06-13 1980-06-13 Production of glutathione

Publications (2)

Publication Number Publication Date
JPS575699A true JPS575699A (en) 1982-01-12
JPS6251600B2 JPS6251600B2 (en) 1987-10-30

Family

ID=13704928

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7996280A Granted JPS575699A (en) 1980-06-13 1980-06-13 Production of glutathione

Country Status (1)

Country Link
JP (1) JPS575699A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020000072A (en) * 2018-06-27 2020-01-09 国立大学法人大阪大学 Method for producing glutathione

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08203265A (en) * 1995-01-26 1996-08-09 Nec Eng Ltd Delay circuit

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020000072A (en) * 2018-06-27 2020-01-09 国立大学法人大阪大学 Method for producing glutathione

Also Published As

Publication number Publication date
JPS6251600B2 (en) 1987-10-30

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