JPS57109787A - Pyrazoloindazole derivative - Google Patents

Pyrazoloindazole derivative

Info

Publication number
JPS57109787A
JPS57109787A JP55184106A JP18410680A JPS57109787A JP S57109787 A JPS57109787 A JP S57109787A JP 55184106 A JP55184106 A JP 55184106A JP 18410680 A JP18410680 A JP 18410680A JP S57109787 A JPS57109787 A JP S57109787A
Authority
JP
Japan
Prior art keywords
compound
pyrazoloindazole
derivative
formulai
cyano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55184106A
Other languages
English (en)
Inventor
Yasuo Fujimura
Sadao Tanaka
Isao Matsunaga
Yasushi Shiraki
Yugo Ikeda
Tamotsu Yamazaki
Yasuhiro Oba
Kazunari Sakai
Shunichi Hata
Minoru Shindo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP55184106A priority Critical patent/JPS57109787A/ja
Priority to US06/331,896 priority patent/US4415569A/en
Priority to DK564781A priority patent/DK564781A/da
Priority to CA000392734A priority patent/CA1175826A/en
Priority to AT81110654T priority patent/ATE10634T1/de
Priority to EP81110654A priority patent/EP0055450B1/en
Priority to DE8181110654T priority patent/DE3167664D1/de
Priority to DE198181110654T priority patent/DE55450T1/de
Priority to ZA818867A priority patent/ZA818867B/xx
Priority to HU813903A priority patent/HU182636B/hu
Priority to AR287947A priority patent/AR229519A1/es
Publication of JPS57109787A publication Critical patent/JPS57109787A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP55184106A 1980-12-26 1980-12-26 Pyrazoloindazole derivative Pending JPS57109787A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP55184106A JPS57109787A (en) 1980-12-26 1980-12-26 Pyrazoloindazole derivative
US06/331,896 US4415569A (en) 1980-12-26 1981-12-17 Pyrazoloindazole derivatives and pharmaceutical composition containing the same
DK564781A DK564781A (da) 1980-12-26 1981-12-18 Fremgangsmaade til fremstilling af pyrazoloindazolderivater
CA000392734A CA1175826A (en) 1980-12-26 1981-12-18 Pyrazoloindazole derivatives, process for preparing the same and pharmaceutical composition containing the same
AT81110654T ATE10634T1 (de) 1980-12-26 1981-12-21 Pyrazoloindazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung.
EP81110654A EP0055450B1 (en) 1980-12-26 1981-12-21 Pyrazoloindazole derivatives, process for preparing the same, and pharmaceutical composition containing the same
DE8181110654T DE3167664D1 (en) 1980-12-26 1981-12-21 Pyrazoloindazole derivatives, process for preparing the same, and pharmaceutical composition containing the same
DE198181110654T DE55450T1 (de) 1980-12-26 1981-12-21 Pyrazoloindazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung.
ZA818867A ZA818867B (en) 1980-12-26 1981-12-22 Pyrazoloindazole derivatives,process for preparing the same,and pharmaceutical compositions containing the same
HU813903A HU182636B (en) 1980-12-26 1981-12-22 Process for producing pyrazolo-imidazol derivatives
AR287947A AR229519A1 (es) 1980-12-26 1981-12-23 Procedimiento de preparacion de derivados de 2,3-dihidro-9-fenil-1h-pirazolo(1,2-a)-indazolio

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55184106A JPS57109787A (en) 1980-12-26 1980-12-26 Pyrazoloindazole derivative

Publications (1)

Publication Number Publication Date
JPS57109787A true JPS57109787A (en) 1982-07-08

Family

ID=16147490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55184106A Pending JPS57109787A (en) 1980-12-26 1980-12-26 Pyrazoloindazole derivative

Country Status (10)

Country Link
US (1) US4415569A (ja)
EP (1) EP0055450B1 (ja)
JP (1) JPS57109787A (ja)
AR (1) AR229519A1 (ja)
AT (1) ATE10634T1 (ja)
CA (1) CA1175826A (ja)
DE (2) DE55450T1 (ja)
DK (1) DK564781A (ja)
HU (1) HU182636B (ja)
ZA (1) ZA818867B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004513882A (ja) * 2000-07-31 2004-05-13 シグナル ファーマシューティカルズ, インコーポレイテッド Jnk阻害剤としてのインダゾール誘導体

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8907799D0 (en) * 1989-04-06 1989-05-17 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
US5260328A (en) * 1989-04-06 1993-11-09 Farmitalia Carlo Erba Srl Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis
US20050009876A1 (en) * 2000-07-31 2005-01-13 Bhagwat Shripad S. Indazole compounds, compositions thereof and methods of treatment therewith
US7211594B2 (en) 2000-07-31 2007-05-01 Signal Pharmaceuticals, Llc Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
US7429599B2 (en) * 2000-12-06 2008-09-30 Signal Pharmaceuticals, Llc Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK
AU2003217961B2 (en) * 2002-03-08 2008-02-28 Signal Pharmaceuticals, Llc Combination therapy for treating, preventing or managing proliferative disorders and cancers
US20040034084A1 (en) * 2002-05-24 2004-02-19 Celgene Corporation Methods for using JNK inhibitors for treating or preventing disease-related wasting
US7008953B2 (en) * 2003-07-30 2006-03-07 Agouron Pharmaceuticals, Inc. 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
US20050090529A1 (en) * 2003-07-31 2005-04-28 Pfizer Inc 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
WO2005051942A1 (en) 2003-11-19 2005-06-09 Signal Pharmaceuticals, Llc Indazole compounds and methods of use thereof as protein kinase inhibitors
US20070004777A1 (en) * 2005-03-23 2007-01-04 Bhagwat Shripad S Methods for treating or preventing acute myelogenous leukemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5615287A (en) * 1979-07-16 1981-02-14 Chugai Pharmaceut Co Ltd Pyrazoloindazole derivative and its preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004513882A (ja) * 2000-07-31 2004-05-13 シグナル ファーマシューティカルズ, インコーポレイテッド Jnk阻害剤としてのインダゾール誘導体

Also Published As

Publication number Publication date
EP0055450B1 (en) 1984-12-05
CA1175826A (en) 1984-10-09
DK564781A (da) 1982-06-27
US4415569A (en) 1983-11-15
HU182636B (en) 1984-02-28
AR229519A1 (es) 1983-09-15
ZA818867B (en) 1982-12-29
DE3167664D1 (en) 1985-01-17
DE55450T1 (de) 1983-03-17
EP0055450A1 (en) 1982-07-07
ATE10634T1 (de) 1984-12-15

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