JPS57109787A - Pyrazoloindazole derivative - Google Patents
Pyrazoloindazole derivativeInfo
- Publication number
- JPS57109787A JPS57109787A JP55184106A JP18410680A JPS57109787A JP S57109787 A JPS57109787 A JP S57109787A JP 55184106 A JP55184106 A JP 55184106A JP 18410680 A JP18410680 A JP 18410680A JP S57109787 A JPS57109787 A JP S57109787A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pyrazoloindazole
- derivative
- formulai
- cyano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55184106A JPS57109787A (en) | 1980-12-26 | 1980-12-26 | Pyrazoloindazole derivative |
US06/331,896 US4415569A (en) | 1980-12-26 | 1981-12-17 | Pyrazoloindazole derivatives and pharmaceutical composition containing the same |
DK564781A DK564781A (da) | 1980-12-26 | 1981-12-18 | Fremgangsmaade til fremstilling af pyrazoloindazolderivater |
CA000392734A CA1175826A (en) | 1980-12-26 | 1981-12-18 | Pyrazoloindazole derivatives, process for preparing the same and pharmaceutical composition containing the same |
AT81110654T ATE10634T1 (de) | 1980-12-26 | 1981-12-21 | Pyrazoloindazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung. |
EP81110654A EP0055450B1 (en) | 1980-12-26 | 1981-12-21 | Pyrazoloindazole derivatives, process for preparing the same, and pharmaceutical composition containing the same |
DE8181110654T DE3167664D1 (en) | 1980-12-26 | 1981-12-21 | Pyrazoloindazole derivatives, process for preparing the same, and pharmaceutical composition containing the same |
DE198181110654T DE55450T1 (de) | 1980-12-26 | 1981-12-21 | Pyrazoloindazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung. |
ZA818867A ZA818867B (en) | 1980-12-26 | 1981-12-22 | Pyrazoloindazole derivatives,process for preparing the same,and pharmaceutical compositions containing the same |
HU813903A HU182636B (en) | 1980-12-26 | 1981-12-22 | Process for producing pyrazolo-imidazol derivatives |
AR287947A AR229519A1 (es) | 1980-12-26 | 1981-12-23 | Procedimiento de preparacion de derivados de 2,3-dihidro-9-fenil-1h-pirazolo(1,2-a)-indazolio |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55184106A JPS57109787A (en) | 1980-12-26 | 1980-12-26 | Pyrazoloindazole derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57109787A true JPS57109787A (en) | 1982-07-08 |
Family
ID=16147490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55184106A Pending JPS57109787A (en) | 1980-12-26 | 1980-12-26 | Pyrazoloindazole derivative |
Country Status (10)
Country | Link |
---|---|
US (1) | US4415569A (ja) |
EP (1) | EP0055450B1 (ja) |
JP (1) | JPS57109787A (ja) |
AR (1) | AR229519A1 (ja) |
AT (1) | ATE10634T1 (ja) |
CA (1) | CA1175826A (ja) |
DE (2) | DE55450T1 (ja) |
DK (1) | DK564781A (ja) |
HU (1) | HU182636B (ja) |
ZA (1) | ZA818867B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004513882A (ja) * | 2000-07-31 | 2004-05-13 | シグナル ファーマシューティカルズ, インコーポレイテッド | Jnk阻害剤としてのインダゾール誘導体 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8907799D0 (en) * | 1989-04-06 | 1989-05-17 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases |
US5260328A (en) * | 1989-04-06 | 1993-11-09 | Farmitalia Carlo Erba Srl | Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis |
US20050009876A1 (en) * | 2000-07-31 | 2005-01-13 | Bhagwat Shripad S. | Indazole compounds, compositions thereof and methods of treatment therewith |
US7211594B2 (en) | 2000-07-31 | 2007-05-01 | Signal Pharmaceuticals, Llc | Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith |
US7429599B2 (en) * | 2000-12-06 | 2008-09-30 | Signal Pharmaceuticals, Llc | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK |
AU2003217961B2 (en) * | 2002-03-08 | 2008-02-28 | Signal Pharmaceuticals, Llc | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
US20040034084A1 (en) * | 2002-05-24 | 2004-02-19 | Celgene Corporation | Methods for using JNK inhibitors for treating or preventing disease-related wasting |
US7008953B2 (en) * | 2003-07-30 | 2006-03-07 | Agouron Pharmaceuticals, Inc. | 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
US20050090529A1 (en) * | 2003-07-31 | 2005-04-28 | Pfizer Inc | 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
WO2005051942A1 (en) | 2003-11-19 | 2005-06-09 | Signal Pharmaceuticals, Llc | Indazole compounds and methods of use thereof as protein kinase inhibitors |
US20070004777A1 (en) * | 2005-03-23 | 2007-01-04 | Bhagwat Shripad S | Methods for treating or preventing acute myelogenous leukemia |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5615287A (en) * | 1979-07-16 | 1981-02-14 | Chugai Pharmaceut Co Ltd | Pyrazoloindazole derivative and its preparation |
-
1980
- 1980-12-26 JP JP55184106A patent/JPS57109787A/ja active Pending
-
1981
- 1981-12-17 US US06/331,896 patent/US4415569A/en not_active Expired - Fee Related
- 1981-12-18 DK DK564781A patent/DK564781A/da not_active Application Discontinuation
- 1981-12-18 CA CA000392734A patent/CA1175826A/en not_active Expired
- 1981-12-21 AT AT81110654T patent/ATE10634T1/de not_active IP Right Cessation
- 1981-12-21 EP EP81110654A patent/EP0055450B1/en not_active Expired
- 1981-12-21 DE DE198181110654T patent/DE55450T1/de active Pending
- 1981-12-21 DE DE8181110654T patent/DE3167664D1/de not_active Expired
- 1981-12-22 ZA ZA818867A patent/ZA818867B/xx unknown
- 1981-12-22 HU HU813903A patent/HU182636B/hu unknown
- 1981-12-23 AR AR287947A patent/AR229519A1/es active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004513882A (ja) * | 2000-07-31 | 2004-05-13 | シグナル ファーマシューティカルズ, インコーポレイテッド | Jnk阻害剤としてのインダゾール誘導体 |
Also Published As
Publication number | Publication date |
---|---|
EP0055450B1 (en) | 1984-12-05 |
CA1175826A (en) | 1984-10-09 |
DK564781A (da) | 1982-06-27 |
US4415569A (en) | 1983-11-15 |
HU182636B (en) | 1984-02-28 |
AR229519A1 (es) | 1983-09-15 |
ZA818867B (en) | 1982-12-29 |
DE3167664D1 (en) | 1985-01-17 |
DE55450T1 (de) | 1983-03-17 |
EP0055450A1 (en) | 1982-07-07 |
ATE10634T1 (de) | 1984-12-15 |
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