JPS5682096A - Production of l-glutamic acid through fermentation process - Google Patents

Production of l-glutamic acid through fermentation process

Info

Publication number
JPS5682096A
JPS5682096A JP16011779A JP16011779A JPS5682096A JP S5682096 A JPS5682096 A JP S5682096A JP 16011779 A JP16011779 A JP 16011779A JP 16011779 A JP16011779 A JP 16011779A JP S5682096 A JPS5682096 A JP S5682096A
Authority
JP
Japan
Prior art keywords
glutamic acid
production
acid
escherichia
plasmid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16011779A
Other languages
Japanese (ja)
Inventor
Takayasu Tsuchida
Shigeru Nakamori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP16011779A priority Critical patent/JPS5682096A/en
Priority to US06/212,245 priority patent/US4393135A/en
Priority to EP80107790A priority patent/EP0030391A3/en
Publication of JPS5682096A publication Critical patent/JPS5682096A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

PURPOSE:A microorganism in Escherichia containing a plasmid in which a deoxyribonucleic acid carrying genetic information concerning the production of L- glutamic acid by Escherichia microorganism is built is cultured to produce L- glutamic acid in high efficiency. CONSTITUTION:A micdoorganism in Escherichia having a plasmid in which the above deoxyribonucleic acid (DNA) is bulit, preferably DNA carrying the genetic information concerning the production of L-glutamic acid, which has been obtained from a mutant resisting lysine analogs, is cultured. The cultivation is done in the same way as in the conventional one, that is, a usual culture medium containing carbon source, nitrogen source, minerals, when necessary, small amounts of organic nutrients such as aminoacids or vitamins is employed. The cultivation is aerobically effected under adjustment in pH to an appropriate value and continued until the accumulation of L-glutamic acid stops. The accumulated L-gultamic acid in the culture medium is collected by a usual method.
JP16011779A 1979-12-10 1979-12-10 Production of l-glutamic acid through fermentation process Pending JPS5682096A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP16011779A JPS5682096A (en) 1979-12-10 1979-12-10 Production of l-glutamic acid through fermentation process
US06/212,245 US4393135A (en) 1979-12-10 1980-12-02 Method for producing L-glutamic acid by fermentation
EP80107790A EP0030391A3 (en) 1979-12-10 1980-12-10 Method for producing l-glutamic acid by fermentation and a method for producing a new microorganism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16011779A JPS5682096A (en) 1979-12-10 1979-12-10 Production of l-glutamic acid through fermentation process

Publications (1)

Publication Number Publication Date
JPS5682096A true JPS5682096A (en) 1981-07-04

Family

ID=15708222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16011779A Pending JPS5682096A (en) 1979-12-10 1979-12-10 Production of l-glutamic acid through fermentation process

Country Status (1)

Country Link
JP (1) JPS5682096A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59232088A (en) * 1983-06-15 1984-12-26 Tanabe Seiyaku Co Ltd Production of l-aspartic acid
JPH03225017A (en) * 1990-01-31 1991-10-04 Komatsu Ltd Engine cooling device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59232088A (en) * 1983-06-15 1984-12-26 Tanabe Seiyaku Co Ltd Production of l-aspartic acid
JPH059061B2 (en) * 1983-06-15 1993-02-03 Tanabe Seiyaku Co
JPH03225017A (en) * 1990-01-31 1991-10-04 Komatsu Ltd Engine cooling device

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